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The map label for this gene is glcD [H]

Identifier: 108762255

GI number: 108762255

Start: 3463546

End: 3464964

Strand: Direct

Name: glcD [H]

Synonym: MXAN_2956

Alternate gene names: 108762255

Gene position: 3463546-3464964 (Clockwise)

Preceding gene: 108763166

Following gene: 108760754

Centisome position: 37.9

GC content: 69.34

Gene sequence:

>1419_bases
ATGAGTGCGCCCCTGCCGCGCGTGGAGCCCGAGCGCGTGGCCCGCGTGCGCGAGGCGCTGGCCGCCGTTCTGGCTCCGGA
GCAGCTGCGCGTGGATGACGCCGCGCTGGCCGCCTACGCCCGTGACGAGTCCGACAGTGGCGTCCATGCGCCCGACCTCG
TCGTCTTCCCCGCGGACACGCGGCAGGTGTCGGAGGTCTTCAAGGCGTGCGCGGTGCACGGCGTGCCCTTCACCCCCTGT
GGCGCGCGCAGCGGCAAGAGCGGCGGCTCGCTGCCCTTGCACGGGGGGGTGGCGGTGAGCCTGGAGCGGATGAACCGCAT
CCTCTCCATCTCCCCCGAGGACCTCACCGCGGTGGTGCAGCCCGGCGTCATCACCGGCGACCTGATGAAGGCCGTGGAAG
CGGTAGGGCTCTTCTATCCACCGGACCCGAACTCCTGGGAGGTGTGCACGCTGGGCGGCAACGTGGCGGAGAACGCCGGC
GGGCCTCGGGCACTCAAATACGGTGTCACGCGCGACTACGTCATCGGACTGGAGTGGGTGCTCCCGGACGGCGAGGTGGT
GCGGGTGGGCCGGCGCACCATCAAGGGTGTGGCGGGTTATGACCTGGTGGGCCTCTTCGTCGGCTCGGAGGGCACGCTGG
GGGTCGCCACCGAAATCACCGTCCAGCTCATCCCGCTGCCGCGCGAGGTGCTGACGGCCCTGGTGGTTTTTCCGTCCGTG
CTGCACGCCGCGCGCGCGGTGTCCGCCGTGCTGGCCGCGGGCATCCTCCCGCGTTGCCTGGAGCTCATCGATGACGTGGC
CCTGCGGGCTGTGGACGGCCGCGGCTTCCAGTTCCCTCCGGGCGCGGGCTCCGCTGTCATCGTCGAGGTGGACGGCAACG
GCCGCGAGGGCTTGCTCGCTGAGCTGTCTCAGTTGGGTGACATCTGTGCCAGCCAGGGCGCCACCGAGACGCTGGTGGCC
CAGGATGCCTCCCAGCGCGAGAAGCTCTGGGCCGCGCGCAGGGTGATTTCCCCAGCCCTCCGGGCCCTCAAGCCTCACAA
GATTTCCGAGGACATCGTCGTGCCCCGCTCGAAGATTCCGGAGGTCATCGAGCGCTTGAAGGCCATGGGCGCGGAGCTGG
GGCTCACCGTGGCCACGTATGGCCATGCGGGCGACGGGAACCTGCACGCCAACATCCTCTACGAGGGCGCCCACCAACGG
CCGCTGGTGGAGGAGGCCCTGCGGCGCATGCTGGTGATGACCGTGGAACTGGGCGGAACCATCACAGGCGAGCACGGTGT
GGGGCACGCGAAGCGGGAATATCTTTCGCTGGAGCAGTCCCCCGCGCTCATCGACCTGCAGCGCAGGCTCAAGGCCTTCT
TCGATCCATCAGGGTTGCTCAACCCTTCGAAAATCTTCCCCGCGCTCATGCGTTCTTGA

Upstream 100 bases:

>100_bases
AGCAGCGCGACGCCGTCACTCACGCGGAGGCCTATGAAGGCACCCTGCGGCGCGACGGCCCCCTGCGCCGTGAGCTGTGG
GCCCGGTTGGGGGCCCGGCG

Downstream 100 bases:

>100_bases
TTCGTGGCCGACGCGGCTCGTTTTTGTCCCGGCGTCGAGCGGCTTACCGTCCAAAGCGTGGGAAGGGCTGGGAATGTCGC
GCGAAATGCCTAATCGGACC

Product: putative glycolate oxidase, GlcD subunit

Products: 2-oxo acid; H2O2

Alternate protein names: NA

Number of amino acids: Translated: 472; Mature: 471

Protein sequence:

>472_residues
MSAPLPRVEPERVARVREALAAVLAPEQLRVDDAALAAYARDESDSGVHAPDLVVFPADTRQVSEVFKACAVHGVPFTPC
GARSGKSGGSLPLHGGVAVSLERMNRILSISPEDLTAVVQPGVITGDLMKAVEAVGLFYPPDPNSWEVCTLGGNVAENAG
GPRALKYGVTRDYVIGLEWVLPDGEVVRVGRRTIKGVAGYDLVGLFVGSEGTLGVATEITVQLIPLPREVLTALVVFPSV
LHAARAVSAVLAAGILPRCLELIDDVALRAVDGRGFQFPPGAGSAVIVEVDGNGREGLLAELSQLGDICASQGATETLVA
QDASQREKLWAARRVISPALRALKPHKISEDIVVPRSKIPEVIERLKAMGAELGLTVATYGHAGDGNLHANILYEGAHQR
PLVEEALRRMLVMTVELGGTITGEHGVGHAKREYLSLEQSPALIDLQRRLKAFFDPSGLLNPSKIFPALMRS

Sequences:

>Translated_472_residues
MSAPLPRVEPERVARVREALAAVLAPEQLRVDDAALAAYARDESDSGVHAPDLVVFPADTRQVSEVFKACAVHGVPFTPC
GARSGKSGGSLPLHGGVAVSLERMNRILSISPEDLTAVVQPGVITGDLMKAVEAVGLFYPPDPNSWEVCTLGGNVAENAG
GPRALKYGVTRDYVIGLEWVLPDGEVVRVGRRTIKGVAGYDLVGLFVGSEGTLGVATEITVQLIPLPREVLTALVVFPSV
LHAARAVSAVLAAGILPRCLELIDDVALRAVDGRGFQFPPGAGSAVIVEVDGNGREGLLAELSQLGDICASQGATETLVA
QDASQREKLWAARRVISPALRALKPHKISEDIVVPRSKIPEVIERLKAMGAELGLTVATYGHAGDGNLHANILYEGAHQR
PLVEEALRRMLVMTVELGGTITGEHGVGHAKREYLSLEQSPALIDLQRRLKAFFDPSGLLNPSKIFPALMRS
>Mature_471_residues
SAPLPRVEPERVARVREALAAVLAPEQLRVDDAALAAYARDESDSGVHAPDLVVFPADTRQVSEVFKACAVHGVPFTPCG
ARSGKSGGSLPLHGGVAVSLERMNRILSISPEDLTAVVQPGVITGDLMKAVEAVGLFYPPDPNSWEVCTLGGNVAENAGG
PRALKYGVTRDYVIGLEWVLPDGEVVRVGRRTIKGVAGYDLVGLFVGSEGTLGVATEITVQLIPLPREVLTALVVFPSVL
HAARAVSAVLAAGILPRCLELIDDVALRAVDGRGFQFPPGAGSAVIVEVDGNGREGLLAELSQLGDICASQGATETLVAQ
DASQREKLWAARRVISPALRALKPHKISEDIVVPRSKIPEVIERLKAMGAELGLTVATYGHAGDGNLHANILYEGAHQRP
LVEEALRRMLVMTVELGGTITGEHGVGHAKREYLSLEQSPALIDLQRRLKAFFDPSGLLNPSKIFPALMRS

Specific function: Unknown

COG id: COG0277

COG function: function code C; FAD/FMN-containing dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding PCMH-type domain [H]

Homologues:

Organism=Homo sapiens, GI37595756, Length=460, Percent_Identity=36.304347826087, Blast_Score=260, Evalue=2e-69,
Organism=Homo sapiens, GI37595754, Length=485, Percent_Identity=34.8453608247423, Blast_Score=249, Evalue=3e-66,
Organism=Homo sapiens, GI119964728, Length=470, Percent_Identity=30.6382978723404, Blast_Score=196, Evalue=4e-50,
Organism=Homo sapiens, GI4501993, Length=458, Percent_Identity=23.5807860262009, Blast_Score=96, Evalue=1e-19,
Organism=Escherichia coli, GI1789351, Length=425, Percent_Identity=38.5882352941176, Blast_Score=271, Evalue=9e-74,
Organism=Escherichia coli, GI1787977, Length=508, Percent_Identity=27.1653543307087, Blast_Score=128, Evalue=9e-31,
Organism=Escherichia coli, GI48994907, Length=449, Percent_Identity=24.9443207126949, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI48994914, Length=127, Percent_Identity=37.7952755905512, Blast_Score=77, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI71992373, Length=458, Percent_Identity=31.4410480349345, Blast_Score=223, Evalue=2e-58,
Organism=Caenorhabditis elegans, GI71992381, Length=458, Percent_Identity=30.3493449781659, Blast_Score=206, Evalue=3e-53,
Organism=Caenorhabditis elegans, GI17534361, Length=485, Percent_Identity=28.659793814433, Blast_Score=188, Evalue=6e-48,
Organism=Caenorhabditis elegans, GI71992392, Length=383, Percent_Identity=31.5926892950392, Blast_Score=183, Evalue=2e-46,
Organism=Caenorhabditis elegans, GI17556096, Length=219, Percent_Identity=26.9406392694064, Blast_Score=96, Evalue=3e-20,
Organism=Saccharomyces cerevisiae, GI6320027, Length=485, Percent_Identity=31.9587628865979, Blast_Score=220, Evalue=3e-58,
Organism=Saccharomyces cerevisiae, GI6320023, Length=469, Percent_Identity=27.2921108742004, Blast_Score=176, Evalue=8e-45,
Organism=Saccharomyces cerevisiae, GI6320764, Length=465, Percent_Identity=28.1720430107527, Blast_Score=167, Evalue=3e-42,
Organism=Drosophila melanogaster, GI18921117, Length=426, Percent_Identity=31.924882629108, Blast_Score=186, Evalue=2e-47,
Organism=Drosophila melanogaster, GI24639277, Length=426, Percent_Identity=31.924882629108, Blast_Score=186, Evalue=2e-47,
Organism=Drosophila melanogaster, GI24639275, Length=426, Percent_Identity=31.924882629108, Blast_Score=186, Evalue=2e-47,
Organism=Drosophila melanogaster, GI24653753, Length=219, Percent_Identity=30.5936073059361, Blast_Score=96, Evalue=8e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016166
- InterPro:   IPR016167
- InterPro:   IPR016164
- InterPro:   IPR016168
- InterPro:   IPR004113
- InterPro:   IPR004490
- InterPro:   IPR006094
- InterPro:   IPR016171 [H]

Pfam domain/function: PF02913 FAD-oxidase_C; PF01565 FAD_binding_4 [H]

EC number: 1.1.3.15

Molecular weight: Translated: 50024; Mature: 49893

Theoretical pI: Translated: 6.03; Mature: 6.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAPLPRVEPERVARVREALAAVLAPEQLRVDDAALAAYARDESDSGVHAPDLVVFPADT
CCCCCCCCCHHHHHHHHHHHHHHHCCHHHCCCHHHHHHHHCCCCCCCCCCCCEEEECCCH
RQVSEVFKACAVHGVPFTPCGARSGKSGGSLPLHGGVAVSLERMNRILSISPEDLTAVVQ
HHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCEEEEHHHHHHHHCCCCHHHHHHHC
PGVITGDLMKAVEAVGLFYPPDPNSWEVCTLGGNVAENAGGPRALKYGVTRDYVIGLEWV
CCCCCHHHHHHHHHHCCEECCCCCCEEEEEECCCHHCCCCCCCEEEECCCCCEEEEEEEE
LPDGEVVRVGRRTIKGVAGYDLVGLFVGSEGTLGVATEITVQLIPLPREVLTALVVFPSV
CCCCCEEHHHHHHHHCCCCCEEEEEEECCCCCEEEEEEEEEEEECCCHHHHHHHHHHHHH
LHAARAVSAVLAAGILPRCLELIDDVALRAVDGRGFQFPPGAGSAVIVEVDGNGREGLLA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCCCEEEEEECCCCCCHHHH
ELSQLGDICASQGATETLVAQDASQREKLWAARRVISPALRALKPHKISEDIVVPRSKIP
HHHHHHHHHHCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHH
EVIERLKAMGAELGLTVATYGHAGDGNLHANILYEGAHQRPLVEEALRRMLVMTVELGGT
HHHHHHHHCCHHCCEEEEECCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHEEEECCCE
ITGEHGVGHAKREYLSLEQSPALIDLQRRLKAFFDPSGLLNPSKIFPALMRS
EECCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHCC
>Mature Secondary Structure 
SAPLPRVEPERVARVREALAAVLAPEQLRVDDAALAAYARDESDSGVHAPDLVVFPADT
CCCCCCCCHHHHHHHHHHHHHHHCCHHHCCCHHHHHHHHCCCCCCCCCCCCEEEECCCH
RQVSEVFKACAVHGVPFTPCGARSGKSGGSLPLHGGVAVSLERMNRILSISPEDLTAVVQ
HHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCEEEEHHHHHHHHCCCCHHHHHHHC
PGVITGDLMKAVEAVGLFYPPDPNSWEVCTLGGNVAENAGGPRALKYGVTRDYVIGLEWV
CCCCCHHHHHHHHHHCCEECCCCCCEEEEEECCCHHCCCCCCCEEEECCCCCEEEEEEEE
LPDGEVVRVGRRTIKGVAGYDLVGLFVGSEGTLGVATEITVQLIPLPREVLTALVVFPSV
CCCCCEEHHHHHHHHCCCCCEEEEEEECCCCCEEEEEEEEEEEECCCHHHHHHHHHHHHH
LHAARAVSAVLAAGILPRCLELIDDVALRAVDGRGFQFPPGAGSAVIVEVDGNGREGLLA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCCCEEEEEECCCCCCHHHH
ELSQLGDICASQGATETLVAQDASQREKLWAARRVISPALRALKPHKISEDIVVPRSKIP
HHHHHHHHHHCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHH
EVIERLKAMGAELGLTVATYGHAGDGNLHANILYEGAHQRPLVEEALRRMLVMTVELGGT
HHHHHHHHCCHHCCEEEEECCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHEEEECCCE
ITGEHGVGHAKREYLSLEQSPALIDLQRRLKAFFDPSGLLNPSKIFPALMRS
EECCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: (S)-2-hydroxy acid; O2

Specific reaction: (S)-2-hydroxy acid + O2 = 2-oxo acid + H2O2

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969504; 9384377 [H]