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The map label for this gene is truD [H]

Identifier: 108762128

GI number: 108762128

Start: 6487585

End: 6488619

Strand: Reverse

Name: truD [H]

Synonym: MXAN_5195

Alternate gene names: 108762128

Gene position: 6488619-6487585 (Counterclockwise)

Preceding gene: 108763931

Following gene: 108757436

Centisome position: 70.99

GC content: 72.17

Gene sequence:

>1035_bases
GTGACGGATTCTGGTTGGCCGCGCCTGACGGCGGAGGTGCCCGGCTGTGGGGGCGCCTTCAAGCTGGTTCCCGAGGACTT
CGAGGTCGAGGAGGTTCCCGCCTACCTGCCTTCCGGCGAGGGCGAGCACCTCTACCTCTGGGTGGAGAAGCGGGGCCGTG
ACACGCGCGAGCTGGTGCGCGCGCTGGCCGCGTCACTGGGCGTGTCCGAGGATGACATTGGCGTGGCGGGGATGAAGGAC
CGGCACGCCATCACCCGGCAGTTGGTGTCCGTGCCCGCGCGCGCCGAGCCGAAGGTGCCGGAGTTCGCCTTGGACGGCGT
CCAGGTGCTGTGGACGAAGCGCCACGGCAACAAGCTCCGCACCGGGCACCTGCGGGGCAACCGCTTCCGCCTGCGCCTGC
GCGACGTGAAGGATTCCGGCGCGGCGCGGGAGACGTTCTCCCGGTTGGTGGCGCAGGGCGTGCCCAACTACTTCGGCGAG
CAGCGCTTCGGCCGGGCAGGGGACAACGCCGACCTGGGCCGGCTGCTGGTGCTGGGCCAGCGGCTGCCGAAGCGGCCGGA
CCGTTTCCAGCGCAAGTTGTACCTGTCCGCCTTCCAGTCGCGCCTCTTCAACCAGGCGCTGGCGGCGCGGCTGCACGCGG
GGACGCTGGCCACCGCGCTCGCCGGCGACGTGCTGCGCAAGGAGGAGACGGGCGGCCTCTTCGTGTGCGAGTCACCCGAG
GTGGACGGCCCCCGCGTGGCCTCCTTCGAGGTGAGCCCGGCAGGCCCGCTCTTCGGGCCGAAGATGACGGCCTCCGCCGG
AGCCGTGGCCGAGCTCGAGGCGCGGCTGCTGGCGGAAGCGGGCGTCACGCCGGAGGACTTCAAGCGCGGCGGTGGTGAGA
CGGAAGGCAGCCGCCGCCCCTACCGCGTCCGCCTGGGCTCGCCCGAGCTGACCGCGGAGAAGACGGCGGACGGCGAGGAC
CTCTGGCTCACCTTCGAGTTGCCTCGGGGCGCGTATGCCACCGAGGTCCTCCACGAGCTGCTCAAGGACGGCTGA

Upstream 100 bases:

>100_bases
TGTTCTTCCTGCTCTTCCAGGCCGGTGAGTTGCTGGAGTCACGCGCGGACGAGGACCTGGCCCGCCGCGTGAAGGAACTG
CTGTCCACGCTCGAGGTATC

Downstream 100 bases:

>100_bases
GCCCCGAAACGACGACGCCTCCGCAGGCGCGAGGCCCCGGAGGCGTCTGGTGCGTCGTGCCCCGGCCAGGTGCGGCCGGG
GCAGGGCGGTTGTTACTCCG

Product: tRNA pseudouridine synthase D

Products: NA

Alternate protein names: tRNA pseudouridylate synthase D; tRNA-uridine isomerase D [H]

Number of amino acids: Translated: 344; Mature: 343

Protein sequence:

>344_residues
MTDSGWPRLTAEVPGCGGAFKLVPEDFEVEEVPAYLPSGEGEHLYLWVEKRGRDTRELVRALAASLGVSEDDIGVAGMKD
RHAITRQLVSVPARAEPKVPEFALDGVQVLWTKRHGNKLRTGHLRGNRFRLRLRDVKDSGAARETFSRLVAQGVPNYFGE
QRFGRAGDNADLGRLLVLGQRLPKRPDRFQRKLYLSAFQSRLFNQALAARLHAGTLATALAGDVLRKEETGGLFVCESPE
VDGPRVASFEVSPAGPLFGPKMTASAGAVAELEARLLAEAGVTPEDFKRGGGETEGSRRPYRVRLGSPELTAEKTADGED
LWLTFELPRGAYATEVLHELLKDG

Sequences:

>Translated_344_residues
MTDSGWPRLTAEVPGCGGAFKLVPEDFEVEEVPAYLPSGEGEHLYLWVEKRGRDTRELVRALAASLGVSEDDIGVAGMKD
RHAITRQLVSVPARAEPKVPEFALDGVQVLWTKRHGNKLRTGHLRGNRFRLRLRDVKDSGAARETFSRLVAQGVPNYFGE
QRFGRAGDNADLGRLLVLGQRLPKRPDRFQRKLYLSAFQSRLFNQALAARLHAGTLATALAGDVLRKEETGGLFVCESPE
VDGPRVASFEVSPAGPLFGPKMTASAGAVAELEARLLAEAGVTPEDFKRGGGETEGSRRPYRVRLGSPELTAEKTADGED
LWLTFELPRGAYATEVLHELLKDG
>Mature_343_residues
TDSGWPRLTAEVPGCGGAFKLVPEDFEVEEVPAYLPSGEGEHLYLWVEKRGRDTRELVRALAASLGVSEDDIGVAGMKDR
HAITRQLVSVPARAEPKVPEFALDGVQVLWTKRHGNKLRTGHLRGNRFRLRLRDVKDSGAARETFSRLVAQGVPNYFGEQ
RFGRAGDNADLGRLLVLGQRLPKRPDRFQRKLYLSAFQSRLFNQALAARLHAGTLATALAGDVLRKEETGGLFVCESPEV
DGPRVASFEVSPAGPLFGPKMTASAGAVAELEARLLAEAGVTPEDFKRGGGETEGSRRPYRVRLGSPELTAEKTADGEDL
WLTFELPRGAYATEVLHELLKDG

Specific function: Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs [H]

COG id: COG0585

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 TRUD domain [H]

Homologues:

Organism=Escherichia coli, GI1789102, Length=333, Percent_Identity=34.8348348348348, Blast_Score=155, Evalue=3e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020103
- InterPro:   IPR001656
- InterPro:   IPR020119
- InterPro:   IPR011760 [H]

Pfam domain/function: PF01142 TruD [H]

EC number: NA

Molecular weight: Translated: 37625; Mature: 37494

Theoretical pI: Translated: 7.67; Mature: 7.67

Prosite motif: PS50984 TRUD ; PS01268 UPF0024

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDSGWPRLTAEVPGCGGAFKLVPEDFEVEEVPAYLPSGEGEHLYLWVEKRGRDTRELVR
CCCCCCCEEEEECCCCCCEEEECCCCCCHHHCCCCCCCCCCCEEEEEEECCCCCHHHHHH
ALAASLGVSEDDIGVAGMKDRHAITRQLVSVPARAEPKVPEFALDGVQVLWTKRHGNKLR
HHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHCCEEEEEEECCCCCEE
TGHLRGNRFRLRLRDVKDSGAARETFSRLVAQGVPNYFGEQRFGRAGDNADLGRLLVLGQ
ECCCCCCEEEEEEECCCCCCHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCHHHHHHHHH
RLPKRPDRFQRKLYLSAFQSRLFNQALAARLHAGTLATALAGDVLRKEETGGLFVCESPE
HCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCC
VDGPRVASFEVSPAGPLFGPKMTASAGAVAELEARLLAEAGVTPEDFKRGGGETEGSRRP
CCCCEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHCCCCCCCCCCCC
YRVRLGSPELTAEKTADGEDLWLTFELPRGAYATEVLHELLKDG
EEEEECCCCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHCC
>Mature Secondary Structure 
TDSGWPRLTAEVPGCGGAFKLVPEDFEVEEVPAYLPSGEGEHLYLWVEKRGRDTRELVR
CCCCCCEEEEECCCCCCEEEECCCCCCHHHCCCCCCCCCCCEEEEEEECCCCCHHHHHH
ALAASLGVSEDDIGVAGMKDRHAITRQLVSVPARAEPKVPEFALDGVQVLWTKRHGNKLR
HHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHCCEEEEEEECCCCCEE
TGHLRGNRFRLRLRDVKDSGAARETFSRLVAQGVPNYFGEQRFGRAGDNADLGRLLVLGQ
ECCCCCCEEEEEEECCCCCCHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCHHHHHHHHH
RLPKRPDRFQRKLYLSAFQSRLFNQALAARLHAGTLATALAGDVLRKEETGGLFVCESPE
HCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCC
VDGPRVASFEVSPAGPLFGPKMTASAGAVAELEARLLAEAGVTPEDFKRGGGETEGSRRP
CCCCEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHCCCCCCCCCCCC
YRVRLGSPELTAEKTADGEDLWLTFELPRGAYATEVLHELLKDG
EEEEECCCCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA