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The map label for this gene is opuAB [H]

Identifier: 108762126

GI number: 108762126

Start: 2599863

End: 2600696

Strand: Direct

Name: opuAB [H]

Synonym: MXAN_2250

Alternate gene names: 108762126

Gene position: 2599863-2600696 (Clockwise)

Preceding gene: 108763523

Following gene: 108759018

Centisome position: 28.45

GC content: 67.99

Gene sequence:

>834_bases
ATGAGCACACTGAGAATCGGCGAAGGCTTCGAGGAGCTGATTGACTGGATGGGCACGCGCGGCGCGCCGGTGTTCGACGC
CATCCGTTCGGGGCTCACGGCCTGCATCAACGGCCTGGAGAGCGCGCTGCTCCTGCCGCCCAGCTACGCCATCATCACGG
TGTTGATGGTGCTCGCCTGGCGCCTGTCCGGCCTGGGCACGGCCGTCTTCACGGCGCTGGGCATGCTGCTCATCCAGGAC
ATGGGCCTGTGGAAGGCGACCATGGAGACGCTGGCGCTGGTCCTCAGCTCGGCGATGGTGGCGCTGGTACTGGGCATCCC
CCTGGGCATCTGGGCCGCGTACAGCCGCGTCGTGGAGCGGGTGCTGCGGCCCGCCCTGGACCTGATGCAGACGATGCCCG
CCTTCGTCTACCTCATCCCCGCGGTGCTCTTCTTCCGGCTGGGGAAGGTGCCCGGCGTGGTGGCCACCGTCATCTTCGCC
ATGCCGCCCGCGGTGCGCCTCACCAACCTGGGCATCCGGCAGGTGCCCACTGAAGTCGTGGAGGCCGCCATCGCGTTTGG
CGCGACGCCGCGTCAGACGCTGCTCAACGTCCAGCTCCCCATCGCCGTCCCCACGCTGCTGGCCGGAGTGAACCAGACCA
TCATGCTGTCGCTGTCCATGGTGGTCATCTCCGCCATGATTGGCGCGGGGGGACTGGGCGAGCAGGTCCTGAAGGGCATC
ACCCAGCTCCGCATCGGGCTGGGCTTCGAGAGCGGCATCGCGGTGGTCATCCTGGCCATCGTGTTGGACCGCCTGACTCA
TGCGCTGGGCAAGCCCCGGACGCGCTCATCATGA

Upstream 100 bases:

>100_bases
ACTCAGATTCCCATCGCCGTCGTCGCCGAGGACCAGTCGTTCCTGGGCATCGTGAGCCGCGCCACGCTGCTGGCCAGCAT
CGCGGGGGAGCAGCCCTGAC

Downstream 100 bases:

>100_bases
AGGAGACCCGTCCCGTGAAGATTTCCTCTCTCAATCGTCTGCCCCTGCTGCTCACGGCCGTGGCGGGGCTGCTCGTCGCC
CCCGGATGCAAGCAGGAGAA

Product: glycine betaine/L-proline ABC transporter permease

Products: ADP; phosphate; L-proline [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 277; Mature: 276

Protein sequence:

>277_residues
MSTLRIGEGFEELIDWMGTRGAPVFDAIRSGLTACINGLESALLLPPSYAIITVLMVLAWRLSGLGTAVFTALGMLLIQD
MGLWKATMETLALVLSSAMVALVLGIPLGIWAAYSRVVERVLRPALDLMQTMPAFVYLIPAVLFFRLGKVPGVVATVIFA
MPPAVRLTNLGIRQVPTEVVEAAIAFGATPRQTLLNVQLPIAVPTLLAGVNQTIMLSLSMVVISAMIGAGGLGEQVLKGI
TQLRIGLGFESGIAVVILAIVLDRLTHALGKPRTRSS

Sequences:

>Translated_277_residues
MSTLRIGEGFEELIDWMGTRGAPVFDAIRSGLTACINGLESALLLPPSYAIITVLMVLAWRLSGLGTAVFTALGMLLIQD
MGLWKATMETLALVLSSAMVALVLGIPLGIWAAYSRVVERVLRPALDLMQTMPAFVYLIPAVLFFRLGKVPGVVATVIFA
MPPAVRLTNLGIRQVPTEVVEAAIAFGATPRQTLLNVQLPIAVPTLLAGVNQTIMLSLSMVVISAMIGAGGLGEQVLKGI
TQLRIGLGFESGIAVVILAIVLDRLTHALGKPRTRSS
>Mature_276_residues
STLRIGEGFEELIDWMGTRGAPVFDAIRSGLTACINGLESALLLPPSYAIITVLMVLAWRLSGLGTAVFTALGMLLIQDM
GLWKATMETLALVLSSAMVALVLGIPLGIWAAYSRVVERVLRPALDLMQTMPAFVYLIPAVLFFRLGKVPGVVATVIFAM
PPAVRLTNLGIRQVPTEVVEAAIAFGATPRQTLLNVQLPIAVPTLLAGVNQTIMLSLSMVVISAMIGAGGLGEQVLKGIT
QLRIGLGFESGIAVVILAIVLDRLTHALGKPRTRSS

Specific function: Involved in a multicomponent binding-protein-dependent transport system for glycine betaine; probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG4176

COG function: function code E; ABC-type proline/glycine betaine transport system, permease component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1789033, Length=267, Percent_Identity=51.310861423221, Blast_Score=250, Evalue=7e-68,
Organism=Escherichia coli, GI1788451, Length=197, Percent_Identity=32.994923857868, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI1788449, Length=209, Percent_Identity=26.3157894736842, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 29354; Mature: 29223

Theoretical pI: Translated: 10.05; Mature: 10.05

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
STLRIGEGFEELIDWMGTRGAPVFDAIRSGLTACINGLESALLLPPSYAIITVLMVLAW
CCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
RLSGLGTAVFTALGMLLIQDMGLWKATMETLALVLSSAMVALVLGIPLGIWAAYSRVVER
HHHCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VLRPALDLMQTMPAFVYLIPAVLFFRLGKVPGVVATVIFAMPPAVRLTNLGIRQVPTEVV
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHCCHHHHHHHHH
EAAIAFGATPRQTLLNVQLPIAVPTLLAGVNQTIMLSLSMVVISAMIGAGGLGEQVLKGI
HHHHHHCCCCHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
TQLRIGLGFESGIAVVILAIVLDRLTHALGKPRTRSS
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-proline [Periplasm]; H2O [C]

Specific reaction: ATP + L-proline [Periplasm] + H2O = ADP + phosphate + L-proline [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7622480; 8969502; 9384377 [H]