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The map label for this gene is mdtA [H]

Identifier: 108762045

GI number: 108762045

Start: 6289051

End: 6290184

Strand: Direct

Name: mdtA [H]

Synonym: MXAN_5031

Alternate gene names: 108762045

Gene position: 6289051-6290184 (Clockwise)

Preceding gene: 108758394

Following gene: 108761223

Centisome position: 68.81

GC content: 72.05

Gene sequence:

>1134_bases
ATGTGGGGTGTCACCCTGCTGGCGGTGGTGGCGGGCTGTTCGGCCCAGAAGGCCGCCCCGCCGGCCCCTCCGCCCCGCGA
GGTGGAAATCGTGACGCTCACCCCGCGCGAGGTGCGCGAAACGGGGGAGTACCTGGGCTCGCTGATGTCGCGGCAGAGCG
TCAACGTGCTGCCCCAGGTCGCGGGCTACGTGCGCAAGATTCACGTGCGTCCCGGTGACAAGGTGGAGGCCGGCGCCGCG
CTCATCGAGGTGGACTCGCGCGAAGGCACCGCCGCGCTCGACAGCGCGCAGGCGCAGCTCAGCTCCACCCAGGTGAGCCT
GGAGCTGGCGCGCCGCACGCTGGAGCGCACCGAGGCGCTCTACAAGGAAGGGCTCGCGAGCGCGCAGGAGCTGGAGCAGG
GCCGCGCGCAGGTGGAGGCAGCCCAGGCCGCGGCGCGTTCATCCGCCGCGCAGGTGACGCAGCGCCAGGTGCAGCTCCAG
TACCACGTGGTGCGCGCGCCCTTCGCCGGCACGATGGGCGACGTGCTGGTGCGGCTGGGTGACTACGTGGGCATGACGAC
GCCGCTCACCAGCGTGGCGCAGTCGGACGTGCTCGAGGTGAGCGTGTCGGTGCCGTCGCCGCGCGCCCGGTCGATGAAGC
CCGACACCGCGCTCGAAATCCTCGACAGCACGGGCAAGGTGCTGATCACCAGCAACGTCTTCTACATCGCGCCCCAGGCG
GACCCCCGTACCCAGTTGGTGGAGGTGAAGGCCGCCTTCCGCAACACCGTGGGCCTGCGGCCCAGCGAGCTGGTGCGCGC
GCGGCTCGTGTACTCGGCCCGGGATGCGCTGCAGATTCCCGCGCTCGCCATCGTGCGGCAGAGCGGTCAGCCCTTCGCGC
TGGTGGTCCTGGCGAAGGACGGGAAGACGGTGGTGGAGCGCCGCCCCATCACGCTCGGCGCGCTGGGCGAGATGGCCTAC
GTGGTGGAGAGCGGGCTCCAGTCGGGCGACCAGGTCGCCGTGTCCTCGCTGCAAGCGCTGCGTGACGGCATGGCGGTGAA
ACCCAAGCAGGCCAACGCCCCCAACGCCCCCACTGGCAGCGGCCCGCCCCGGGCCTCTGGCAATGGTGGCGGCACTGTCG
GCGGGAGCCGCTGA

Upstream 100 bases:

>100_bases
CGGAGCTGACCCTGGTGCTGCGTGAATTCGAGCTCGTCCAGGCGCGCCTGGACGCATTCCTGACGGAGGCGCGGTGCGAC
TGGTGAATCAGATGAAGGCG

Downstream 100 bases:

>100_bases
ACGAAGGGCCGGATAGAGCACCATGTTCGTCGATTTCTTCATCCGTAGGCCCGTCTTCGCCATCGTCTGCTCCATCCTGC
TGACGCTGGTGGGGCTGATT

Product: HAE1 family efflux transporter MFP subunit

Products: NA

Alternate protein names: Multidrug transporter mdtA [H]

Number of amino acids: Translated: 377; Mature: 377

Protein sequence:

>377_residues
MWGVTLLAVVAGCSAQKAAPPAPPPREVEIVTLTPREVRETGEYLGSLMSRQSVNVLPQVAGYVRKIHVRPGDKVEAGAA
LIEVDSREGTAALDSAQAQLSSTQVSLELARRTLERTEALYKEGLASAQELEQGRAQVEAAQAAARSSAAQVTQRQVQLQ
YHVVRAPFAGTMGDVLVRLGDYVGMTTPLTSVAQSDVLEVSVSVPSPRARSMKPDTALEILDSTGKVLITSNVFYIAPQA
DPRTQLVEVKAAFRNTVGLRPSELVRARLVYSARDALQIPALAIVRQSGQPFALVVLAKDGKTVVERRPITLGALGEMAY
VVESGLQSGDQVAVSSLQALRDGMAVKPKQANAPNAPTGSGPPRASGNGGGTVGGSR

Sequences:

>Translated_377_residues
MWGVTLLAVVAGCSAQKAAPPAPPPREVEIVTLTPREVRETGEYLGSLMSRQSVNVLPQVAGYVRKIHVRPGDKVEAGAA
LIEVDSREGTAALDSAQAQLSSTQVSLELARRTLERTEALYKEGLASAQELEQGRAQVEAAQAAARSSAAQVTQRQVQLQ
YHVVRAPFAGTMGDVLVRLGDYVGMTTPLTSVAQSDVLEVSVSVPSPRARSMKPDTALEILDSTGKVLITSNVFYIAPQA
DPRTQLVEVKAAFRNTVGLRPSELVRARLVYSARDALQIPALAIVRQSGQPFALVVLAKDGKTVVERRPITLGALGEMAY
VVESGLQSGDQVAVSSLQALRDGMAVKPKQANAPNAPTGSGPPRASGNGGGTVGGSR
>Mature_377_residues
MWGVTLLAVVAGCSAQKAAPPAPPPREVEIVTLTPREVRETGEYLGSLMSRQSVNVLPQVAGYVRKIHVRPGDKVEAGAA
LIEVDSREGTAALDSAQAQLSSTQVSLELARRTLERTEALYKEGLASAQELEQGRAQVEAAQAAARSSAAQVTQRQVQLQ
YHVVRAPFAGTMGDVLVRLGDYVGMTTPLTSVAQSDVLEVSVSVPSPRARSMKPDTALEILDSTGKVLITSNVFYIAPQA
DPRTQLVEVKAAFRNTVGLRPSELVRARLVYSARDALQIPALAIVRQSGQPFALVVLAKDGKTVVERRPITLGALGEMAY
VVESGLQSGDQVAVSSLQALRDGMAVKPKQANAPNAPTGSGPPRASGNGGGTVGGSR

Specific function: Unknown

COG id: COG0845

COG function: function code M; Membrane-fusion protein

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI87082036, Length=370, Percent_Identity=27.2972972972973, Blast_Score=109, Evalue=3e-25,
Organism=Escherichia coli, GI1789929, Length=373, Percent_Identity=29.2225201072386, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI1786668, Length=395, Percent_Identity=30.8860759493671, Blast_Score=99, Evalue=4e-22,
Organism=Escherichia coli, GI1789665, Length=361, Percent_Identity=30.1939058171745, Blast_Score=96, Evalue=4e-21,
Organism=Escherichia coli, GI87081951, Length=149, Percent_Identity=30.8724832214765, Blast_Score=72, Evalue=5e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022824
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 39673; Mature: 39673

Theoretical pI: Translated: 9.70; Mature: 9.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MWGVTLLAVVAGCSAQKAAPPAPPPREVEIVTLTPREVRETGEYLGSLMSRQSVNVLPQV
CCHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECHHHHHHHHHHHHHHHHCCHHHHHHHH
AGYVRKIHVRPGDKVEAGAALIEVDSREGTAALDSAQAQLSSTQVSLELARRTLERTEAL
HHHHEEEECCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YKEGLASAQELEQGRAQVEAAQAAARSSAAQVTQRQVQLQYHVVRAPFAGTMGDVLVRLG
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCHHHHHHHHHH
DYVGMTTPLTSVAQSDVLEVSVSVPSPRARSMKPDTALEILDSTGKVLITSNVFYIAPQA
HHCCCCCCHHHHHHCCEEEEEEECCCCCCCCCCCHHHHHHHHCCCCEEEECCEEEEECCC
DPRTQLVEVKAAFRNTVGLRPSELVRARLVYSARDALQIPALAIVRQSGQPFALVVLAKD
CCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCHHHEECCCCCCEEEEEEECC
GKTVVERRPITLGALGEMAYVVESGLQSGDQVAVSSLQALRDGMAVKPKQANAPNAPTGS
CCCHHHCCCCEEEHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
GPPRASGNGGGTVGGSR
CCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MWGVTLLAVVAGCSAQKAAPPAPPPREVEIVTLTPREVRETGEYLGSLMSRQSVNVLPQV
CCHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECHHHHHHHHHHHHHHHHCCHHHHHHHH
AGYVRKIHVRPGDKVEAGAALIEVDSREGTAALDSAQAQLSSTQVSLELARRTLERTEAL
HHHHEEEECCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YKEGLASAQELEQGRAQVEAAQAAARSSAAQVTQRQVQLQYHVVRAPFAGTMGDVLVRLG
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCHHHHHHHHHH
DYVGMTTPLTSVAQSDVLEVSVSVPSPRARSMKPDTALEILDSTGKVLITSNVFYIAPQA
HHCCCCCCHHHHHHCCEEEEEEECCCCCCCCCCCHHHHHHHHCCCCEEEECCEEEEECCC
DPRTQLVEVKAAFRNTVGLRPSELVRARLVYSARDALQIPALAIVRQSGQPFALVVLAKD
CCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCHHHEECCCCCCEEEEEEECC
GKTVVERRPITLGALGEMAYVVESGLQSGDQVAVSSLQALRDGMAVKPKQANAPNAPTGS
CCCHHHCCCCEEEHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
GPPRASGNGGGTVGGSR
CCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA