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The map label for this gene is clpC [H]

Identifier: 108762006

GI number: 108762006

Start: 5129944

End: 5132463

Strand: Direct

Name: clpC [H]

Synonym: MXAN_4178

Alternate gene names: 108762006

Gene position: 5129944-5132463 (Clockwise)

Preceding gene: 108757892

Following gene: 108763596

Centisome position: 56.13

GC content: 72.1

Gene sequence:

>2520_bases
ATGGTCGATAGCACGGACCTCGCGCAGGTCCTCCACGAAGCGAATGACATCGCACAGAGCGTGGTTCAGAGGGTCACCTC
CGCCCACGTGCTCCTGGCGCTCTTCACGGTGGAGAACCGTGCACAGCTGCTGCTCAAGGAGCGAGGCGTGGACGAGGACG
CCATCCTCCAGCTGCTGACGGCCGCTCCCGCGGAGCCGGACAGCCTGCTCCGGGAGCTGCGCGAGAAGACCCGGGAGATC
GCCTCCAATGTGGGCTCCCAGGAGGCGGACTGCCTCCACCTGCTCATCGCCGTGGCCCGGGTGCGCTGCGCGGCCCAGGA
GCTGCTGCTGCAGGCCGGGCTGGACCTGGGCGGCCTCATGCGCATGGCGATGTCCTATTTCACCAGTGGTCACATGCCGC
GCCGCCTCCAACTGGGCCGGTCACAGACCCTGGGGCCCCGGCCCGCGAGCCGCCCCCTGGGCGCGCCGCCGTCTCCCCTT
CCGGCCTCCGCCATCACGCTGAGCCTGCCGCGCTCCCGGCCTGGCGCCCCGCCGTCGTCGCCCCCGCCCTTCACCGCGCC
GCCACCGCCGCCGCGCTACAGCACGCCCGCGCTGTCGCCGCGCGATCTCATCGATGTGGACGAGGAGCCGGAGGCGCCGC
CGCCCGAGCCCGTGGCACGCGCCGCGCCGTCCCCTGCCCCGACCTCCAAGGCCGCCCCCGCACCCGCGGGCCGGCAGGCG
CAGTCCGCCGCCGCGTCGCCCGTGCTCGACGCCAAGGCCTACCCCCTGCTCACCTCGCTGGGCCGAAACCTGAGCCAGGC
CGCCCACGAGGGCCGCCTGGACCCGGTGGTGGGCCGCGCGCGCGAGGTCGAGGAGGTCATCGACATCCTGGGCAAGCGGC
GCACCAACAACCCCTGCCTGCTGGGCGAGCCTGGCGTGGGCAAGACGGCGGTGGTGGAGGGCGTGGCGCAGCGCCTGCTC
GAGCTGCGTGGGTCGCTGTCGGAGAAGGTGCTGGTGGAGCTGGACATGGCCACGCTGGTGGCCGGCACGCAGCTGCGCGG
CTCGTTCTCCGAGAAGCTCAACGCGCTGAAGGAAGAGGTCCGCCGCGCCGAGGGCCGCGTGGTGGTCTTCATCGACGAAA
TCCACACGCTGGTGGGCGCGGGCTCCACGGGTGACGGTCCGCAGGACGCGGCCAACGAGCTGAAGACGGCCATGGCGCGC
GGTGAGTTCCCCTGCATCGGCGCCACCACGCACGACGAGTACCGCAAGTTCATCAGCACCGACCCGGCCCTGGAGCGCCG
CTTCACCCCCGTGGTGGTCAACGAGCCCTCCGTACCGGAGACGGTGGAGATCCTCCGCGGCATCATCGGCCGCTACGAGG
AGCACCACGGGCTGCGCTACACGCCCGAGGCGCTGGAGGCCGCGACGTCCCTGGCCAGCCGCTACGTGACGGACCGCTTC
ATGCCGGACAAGGCCATCTCCGTGGTGGACCTGGCGGGCAGCCGCTGCCACCGCGAGGGCCGCGACGTGGTGGAGCCCGC
CGACGTGGCGCGCGTGGTGGCCAAGCTCGCGGGCGTCCCCGAGGAGCGCCTGCTGATGAACGACTCGTCGCGTCTGCTCC
GGCTGGAGCAGGACCTGGCGGAGCGCGTCATCGGGCACTCGGAGGCAGTCACGCGCATCGCCCGGGTCATCCGCCGCAAC
TACGCGGGCTTCGCGTCGCGCCGCCCCATGGGCAGCTTCCTCTTCCTGGGCCCCACGGGCGTGGGCAAGACGGAGATGGC
CCGCGCGCTGGCGGACGTGCTGTTCGGCAGCCGCGACTCGCTGGTGCGCCTGGACATGAGCGAGATGTCCGAACAGCACG
GCGTCTCGCGCCTCATCGGCTCGCCCGCCGGCTACGTGGGCTTCGGTGAGGGCGGACAGCTCACGGAGCCCGTGCGCCGC
CGGCCCTCGTCGGTGGTGGTGCTGGACGAAATCGAGAAGGCGCACCGCGAGGTGCAGATGCTCCTCCTCCAGGTCCTGGA
GGAAGGCCGCCTGACGGACGGCAAGGGGCGCCACATCGACTTCTCCAACACCGTCATCGTCATGACGACGAACCTGGGTG
CGGAGGCCTTCTCCCGCACCGGCCGCCCGGTGGGCTTCGGCGCGGACTCCGCGGGCCCCGGGGACGCCATGGACATGGCA
TCTTCGGTGGCGCGCAAGGCGCTGCCGCCGGAGCTGTGGAACCGCATCGACGAACGGCTCCCCTTCCGTCCCCTGGCGGA
GGTGGAGGTGGCACGCATCGCCACGCTGCTGCTGGAGGAGAGCAGCAAGCGCCTGACCACCGAACGCGGCATTGAATACG
TGGCGGGCGACGACGTGGTCGGCCACCTGCTGAAGTCCGGCGGCTTCGACCCGCAACTGGGCGCGCGCCCCATGCGACAG
ATGGTGCAGCGGCTGGTGGAGGGCCCCCTCGCGGAGCGCATCCTGTCGGGCGAGTTCGTCACGGGCGACCGCGTGCGCAT
CGCGGTGAACTCCGGACAGCTCCAGTTCCAGCGCGAGTGA

Upstream 100 bases:

>100_bases
CTCCAGGGCTTTACGGCACATGTAGCGGCCTGTAGCGGAAATTTTGCCGGACGCCCCAAGAGGGTGTATTGCGCTCGTCT
GGTCGCTTGCCGGAGTTCGA

Downstream 100 bases:

>100_bases
TGAGCCCCAGCCCCCGCCCCCGCGCAGGGCCTTCGAAACGGCGCCCACCCGTCGTGATTGTCGGGATGGGCCGCCTGGGG
GGCGCCCTCGGGCTGGCGCT

Product: ClpA/B family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 839; Mature: 839

Protein sequence:

>839_residues
MVDSTDLAQVLHEANDIAQSVVQRVTSAHVLLALFTVENRAQLLLKERGVDEDAILQLLTAAPAEPDSLLRELREKTREI
ASNVGSQEADCLHLLIAVARVRCAAQELLLQAGLDLGGLMRMAMSYFTSGHMPRRLQLGRSQTLGPRPASRPLGAPPSPL
PASAITLSLPRSRPGAPPSSPPPFTAPPPPPRYSTPALSPRDLIDVDEEPEAPPPEPVARAAPSPAPTSKAAPAPAGRQA
QSAAASPVLDAKAYPLLTSLGRNLSQAAHEGRLDPVVGRAREVEEVIDILGKRRTNNPCLLGEPGVGKTAVVEGVAQRLL
ELRGSLSEKVLVELDMATLVAGTQLRGSFSEKLNALKEEVRRAEGRVVVFIDEIHTLVGAGSTGDGPQDAANELKTAMAR
GEFPCIGATTHDEYRKFISTDPALERRFTPVVVNEPSVPETVEILRGIIGRYEEHHGLRYTPEALEAATSLASRYVTDRF
MPDKAISVVDLAGSRCHREGRDVVEPADVARVVAKLAGVPEERLLMNDSSRLLRLEQDLAERVIGHSEAVTRIARVIRRN
YAGFASRRPMGSFLFLGPTGVGKTEMARALADVLFGSRDSLVRLDMSEMSEQHGVSRLIGSPAGYVGFGEGGQLTEPVRR
RPSSVVVLDEIEKAHREVQMLLLQVLEEGRLTDGKGRHIDFSNTVIVMTTNLGAEAFSRTGRPVGFGADSAGPGDAMDMA
SSVARKALPPELWNRIDERLPFRPLAEVEVARIATLLLEESSKRLTTERGIEYVAGDDVVGHLLKSGGFDPQLGARPMRQ
MVQRLVEGPLAERILSGEFVTGDRVRIAVNSGQLQFQRE

Sequences:

>Translated_839_residues
MVDSTDLAQVLHEANDIAQSVVQRVTSAHVLLALFTVENRAQLLLKERGVDEDAILQLLTAAPAEPDSLLRELREKTREI
ASNVGSQEADCLHLLIAVARVRCAAQELLLQAGLDLGGLMRMAMSYFTSGHMPRRLQLGRSQTLGPRPASRPLGAPPSPL
PASAITLSLPRSRPGAPPSSPPPFTAPPPPPRYSTPALSPRDLIDVDEEPEAPPPEPVARAAPSPAPTSKAAPAPAGRQA
QSAAASPVLDAKAYPLLTSLGRNLSQAAHEGRLDPVVGRAREVEEVIDILGKRRTNNPCLLGEPGVGKTAVVEGVAQRLL
ELRGSLSEKVLVELDMATLVAGTQLRGSFSEKLNALKEEVRRAEGRVVVFIDEIHTLVGAGSTGDGPQDAANELKTAMAR
GEFPCIGATTHDEYRKFISTDPALERRFTPVVVNEPSVPETVEILRGIIGRYEEHHGLRYTPEALEAATSLASRYVTDRF
MPDKAISVVDLAGSRCHREGRDVVEPADVARVVAKLAGVPEERLLMNDSSRLLRLEQDLAERVIGHSEAVTRIARVIRRN
YAGFASRRPMGSFLFLGPTGVGKTEMARALADVLFGSRDSLVRLDMSEMSEQHGVSRLIGSPAGYVGFGEGGQLTEPVRR
RPSSVVVLDEIEKAHREVQMLLLQVLEEGRLTDGKGRHIDFSNTVIVMTTNLGAEAFSRTGRPVGFGADSAGPGDAMDMA
SSVARKALPPELWNRIDERLPFRPLAEVEVARIATLLLEESSKRLTTERGIEYVAGDDVVGHLLKSGGFDPQLGARPMRQ
MVQRLVEGPLAERILSGEFVTGDRVRIAVNSGQLQFQRE
>Mature_839_residues
MVDSTDLAQVLHEANDIAQSVVQRVTSAHVLLALFTVENRAQLLLKERGVDEDAILQLLTAAPAEPDSLLRELREKTREI
ASNVGSQEADCLHLLIAVARVRCAAQELLLQAGLDLGGLMRMAMSYFTSGHMPRRLQLGRSQTLGPRPASRPLGAPPSPL
PASAITLSLPRSRPGAPPSSPPPFTAPPPPPRYSTPALSPRDLIDVDEEPEAPPPEPVARAAPSPAPTSKAAPAPAGRQA
QSAAASPVLDAKAYPLLTSLGRNLSQAAHEGRLDPVVGRAREVEEVIDILGKRRTNNPCLLGEPGVGKTAVVEGVAQRLL
ELRGSLSEKVLVELDMATLVAGTQLRGSFSEKLNALKEEVRRAEGRVVVFIDEIHTLVGAGSTGDGPQDAANELKTAMAR
GEFPCIGATTHDEYRKFISTDPALERRFTPVVVNEPSVPETVEILRGIIGRYEEHHGLRYTPEALEAATSLASRYVTDRF
MPDKAISVVDLAGSRCHREGRDVVEPADVARVVAKLAGVPEERLLMNDSSRLLRLEQDLAERVIGHSEAVTRIARVIRRN
YAGFASRRPMGSFLFLGPTGVGKTEMARALADVLFGSRDSLVRLDMSEMSEQHGVSRLIGSPAGYVGFGEGGQLTEPVRR
RPSSVVVLDEIEKAHREVQMLLLQVLEEGRLTDGKGRHIDFSNTVIVMTTNLGAEAFSRTGRPVGFGADSAGPGDAMDMA
SSVARKALPPELWNRIDERLPFRPLAEVEVARIATLLLEESSKRLTTERGIEYVAGDDVVGHLLKSGGFDPQLGARPMRQ
MVQRLVEGPLAERILSGEFVTGDRVRIAVNSGQLQFQRE

Specific function: ATP-Dependent Specificity Component Of The Clpp Protease. It Directs The Protease To Specific Substrates. The Primary Function Of The Clpa-Clpp Complex Appears To Be The Degradation Of Unfolded Or Abnormal Proteins. [C]

COG id: COG0542

COG function: function code O; ATPases with chaperone activity, ATP-binding subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 UVR domain [H]

Homologues:

Organism=Homo sapiens, GI13540606, Length=324, Percent_Identity=31.7901234567901, Blast_Score=169, Evalue=1e-41,
Organism=Escherichia coli, GI1787109, Length=581, Percent_Identity=39.4148020654045, Blast_Score=409, Evalue=1e-115,
Organism=Escherichia coli, GI1788943, Length=335, Percent_Identity=48.3582089552239, Blast_Score=311, Evalue=1e-85,
Organism=Saccharomyces cerevisiae, GI6320464, Length=334, Percent_Identity=41.6167664670659, Blast_Score=266, Evalue=8e-72,
Organism=Saccharomyces cerevisiae, GI6323002, Length=426, Percent_Identity=31.4553990610329, Blast_Score=221, Evalue=4e-58,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR003959
- InterPro:   IPR018368
- InterPro:   IPR001270
- InterPro:   IPR019489
- InterPro:   IPR004176
- InterPro:   IPR023150
- InterPro:   IPR001943 [H]

Pfam domain/function: PF00004 AAA; PF07724 AAA_2; PF02861 Clp_N; PF10431 ClpB_D2-small; PF02151 UVR [H]

EC number: NA

Molecular weight: Translated: 90609; Mature: 90609

Theoretical pI: Translated: 6.27; Mature: 6.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVDSTDLAQVLHEANDIAQSVVQRVTSAHVLLALFTVENRAQLLLKERGVDEDAILQLLT
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
AAPAEPDSLLRELREKTREIASNVGSQEADCLHLLIAVARVRCAAQELLLQAGLDLGGLM
HCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
RMAMSYFTSGHMPRRLQLGRSQTLGPRPASRPLGAPPSPLPASAITLSLPRSRPGAPPSS
HHHHHHHHCCCCCHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCC
PPPFTAPPPPPRYSTPALSPRDLIDVDEEPEAPPPEPVARAAPSPAPTSKAAPAPAGRQA
CCCCCCCCCCCCCCCCCCCCHHCCCCCCCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCHH
QSAAASPVLDAKAYPLLTSLGRNLSQAAHEGRLDPVVGRAREVEEVIDILGKRRTNNPCL
HHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCCEE
LGEPGVGKTAVVEGVAQRLLELRGSLSEKVLVELDMATLVAGTQLRGSFSEKLNALKEEV
ECCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHEEHHHHHHHCHHHHCHHHHHHHHHHHHH
RRAEGRVVVFIDEIHTLVGAGSTGDGPQDAANELKTAMARGEFPCIGATTHDEYRKFIST
HHHCCCEEEEHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCEECCCCHHHHHHHHCC
DPALERRFTPVVVNEPSVPETVEILRGIIGRYEEHHGLRYTPEALEAATSLASRYVTDRF
CHHHHHCCCCEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHC
MPDKAISVVDLAGSRCHREGRDVVEPADVARVVAKLAGVPEERLLMNDSSRLLRLEQDLA
CCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCHHHHHHCCCHHHHHHHHHHH
ERVIGHSEAVTRIARVIRRNYAGFASRRPMGSFLFLGPTGVGKTEMARALADVLFGSRDS
HHHHCCHHHHHHHHHHHHHHHCCHHCCCCCCCEEEECCCCCCHHHHHHHHHHHHHCCCCC
LVRLDMSEMSEQHGVSRLIGSPAGYVGFGEGGQLTEPVRRRPSSVVVLDEIEKAHREVQM
EEEECHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHCCCCCEEEHHHHHHHHHHHHH
LLLQVLEEGRLTDGKGRHIDFSNTVIVMTTNLGAEAFSRTGRPVGFGADSAGPGDAMDMA
HHHHHHHHCCCCCCCCCEEECCCEEEEEEECCCHHHHHHCCCCCCCCCCCCCCCHHHHHH
SSVARKALPPELWNRIDERLPFRPLAEVEVARIATLLLEESSKRLTTERGIEYVAGDDVV
HHHHHHCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCHHH
GHLLKSGGFDPQLGARPMRQMVQRLVEGPLAERILSGEFVTGDRVRIAVNSGQLQFQRE
HHHHHCCCCCCCCCCHHHHHHHHHHHHCHHHHHHHCCCCCCCCEEEEEEECCCEEEECC
>Mature Secondary Structure
MVDSTDLAQVLHEANDIAQSVVQRVTSAHVLLALFTVENRAQLLLKERGVDEDAILQLLT
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
AAPAEPDSLLRELREKTREIASNVGSQEADCLHLLIAVARVRCAAQELLLQAGLDLGGLM
HCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
RMAMSYFTSGHMPRRLQLGRSQTLGPRPASRPLGAPPSPLPASAITLSLPRSRPGAPPSS
HHHHHHHHCCCCCHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCC
PPPFTAPPPPPRYSTPALSPRDLIDVDEEPEAPPPEPVARAAPSPAPTSKAAPAPAGRQA
CCCCCCCCCCCCCCCCCCCCHHCCCCCCCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCHH
QSAAASPVLDAKAYPLLTSLGRNLSQAAHEGRLDPVVGRAREVEEVIDILGKRRTNNPCL
HHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCCEE
LGEPGVGKTAVVEGVAQRLLELRGSLSEKVLVELDMATLVAGTQLRGSFSEKLNALKEEV
ECCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHEEHHHHHHHCHHHHCHHHHHHHHHHHHH
RRAEGRVVVFIDEIHTLVGAGSTGDGPQDAANELKTAMARGEFPCIGATTHDEYRKFIST
HHHCCCEEEEHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCEECCCCHHHHHHHHCC
DPALERRFTPVVVNEPSVPETVEILRGIIGRYEEHHGLRYTPEALEAATSLASRYVTDRF
CHHHHHCCCCEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHC
MPDKAISVVDLAGSRCHREGRDVVEPADVARVVAKLAGVPEERLLMNDSSRLLRLEQDLA
CCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCHHHHHHCCCHHHHHHHHHHH
ERVIGHSEAVTRIARVIRRNYAGFASRRPMGSFLFLGPTGVGKTEMARALADVLFGSRDS
HHHHCCHHHHHHHHHHHHHHHCCHHCCCCCCCEEEECCCCCCHHHHHHHHHHHHHCCCCC
LVRLDMSEMSEQHGVSRLIGSPAGYVGFGEGGQLTEPVRRRPSSVVVLDEIEKAHREVQM
EEEECHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHCCCCCEEEHHHHHHHHHHHHH
LLLQVLEEGRLTDGKGRHIDFSNTVIVMTTNLGAEAFSRTGRPVGFGADSAGPGDAMDMA
HHHHHHHHCCCCCCCCCEEECCCEEEEEEECCCHHHHHHCCCCCCCCCCCCCCCHHHHHH
SSVARKALPPELWNRIDERLPFRPLAEVEVARIATLLLEESSKRLTTERGIEYVAGDDVV
HHHHHHCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCHHH
GHLLKSGGFDPQLGARPMRQMVQRLVEGPLAERILSGEFVTGDRVRIAVNSGQLQFQRE
HHHHHCCCCCCCCCCHHHHHHHHHHHHCHHHHHHHCCCCCCCCEEEEEEECCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]