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The map label for this gene is kdtA [H]

Identifier: 108761887

GI number: 108761887

Start: 5907090

End: 5908373

Strand: Reverse

Name: kdtA [H]

Synonym: MXAN_4714

Alternate gene names: 108761887

Gene position: 5908373-5907090 (Counterclockwise)

Preceding gene: 108764005

Following gene: 108763150

Centisome position: 64.64

GC content: 69.86

Gene sequence:

>1284_bases
ATGCGCGTCCTCTACGTCCTCGTCACCTACCTGCTCTTCGCAGTCCTGTTCCCGGTGCTCGCACTGCACCGGAAGACGCG
CCATGGGCTGATGGAGCGCTTGGGCTTCTATGGCCCGCACAGCCACCTGCCTCCCGGGGACGGGCCCGTCCTCTGGCTGC
ATGGCGCGAGCGCCGGGGACCTGCTGGCCCTCTCGCCGATGTTCGGCCCGCTGCGGGCTCGTTTCCCGGGCTGCCGCCTG
TTGCTGTCGACCATGACGGACAGCGGCTACGCGATGGCGAAGGGCCGGCTGGCCAACGACATCGACGGGGTCGTCTACGT
GCCCTATGACCTCTGGGGCGCGACGCGGCGAGCGGTCCGGGCCATCCGTCCGGACGTACTGGTGCTGGAGTACACCGAAA
TCTGGCCCAACCTCATCCGCGCGGCGAAGCGGGGTGGGGCGCGAGTGGTGATGACGAACGGGCGCTTTTCGCCCGCGAAC
GTCGGGAAGTACCAGACGCTGTTCCGCCTCATCGGCAACCCGCTGCGGGATTTGGACCTCCTCCTCATGCGCGAGGAGGA
CGAAGCCGTCCGTGCGCGGCAGCTCGGTGCCAGGCCGGACTGGGTGAAGGTGACGGGGAACACGAAGTTCGACGCGCTCG
CCGCGGGCCCGGTGCCCGAGGACGAGAACCTTCGCACGGCGCTGGGCCTGACGCCGGGCGAGCGGGTATGGATTGCCGGA
AGCACCCATGAGGGCGAGGAAGCCCAGCTCCTGGGGGTGTACGCGCGGCTGCGCGAGCGGTGGCCGGAGCTGCGGTTGGT
GATTGCCCCCAGGTACGTGGACCGGGCGGCGCGAATCGTGACGCTTGCGCGCGAGGCGGGACTGAGCGTGGGGCTGCGCT
CGCAGGGCAATCCGGAGCGGGGCCAGGTCGTGGTGCTGGACACCATCGGCGAGCTGTCGAGGGCCTACCGGCTGGCGACG
GTGGTGTTCGTCGGCGGCTCGTTCACGACGCGCGGCGGGCAGAACATCCTGGAGCCCGCGGGGCAGGGGAAGCCGGTGCT
CTACGGGCCGCACATGGACAACTTCCGGGACAGTGTCGCGTTGCTGACAGGGCAGGGTGGGCTCCAGGTTCAGGACGCCG
CGGCCTTGGAGCAGGCGCTCGTGTCGCTGCTCGAATCACCGGAGCGGCTCGCGAGCCTGGGTGCCCAGGCGCTGGAGACG
GTGGGCCGTATTTCGGGCGCCAGTGAAAGGAACGCGGAGGCGATGACGACGTTGTTTCCGCACGGGAGGCCGGACCCGCG
ATGA

Upstream 100 bases:

>100_bases
CGCTTCTTCGGGACGGAATGGCGGCCCTGGTTGGTGCCCAGCCCCGTGCGCGTGCTGCCCCCGGGGCCGGGCATCTGATA
GACGGCGCGACCAGCCGCCC

Downstream 100 bases:

>100_bases
CACTCATCGTCCATCCGCATTTCCACCACCGCTACACGGGCGTGACGCGCCACGTGGAGACGGTGGTACCCGCGCTCGTC
CGGGATTCAGGCTCGGAGAC

Product: 3-deoxy-D-manno-octulosonic-acid transferase

Products: NA

Alternate protein names: KDO transferase [H]

Number of amino acids: Translated: 427; Mature: 427

Protein sequence:

>427_residues
MRVLYVLVTYLLFAVLFPVLALHRKTRHGLMERLGFYGPHSHLPPGDGPVLWLHGASAGDLLALSPMFGPLRARFPGCRL
LLSTMTDSGYAMAKGRLANDIDGVVYVPYDLWGATRRAVRAIRPDVLVLEYTEIWPNLIRAAKRGGARVVMTNGRFSPAN
VGKYQTLFRLIGNPLRDLDLLLMREEDEAVRARQLGARPDWVKVTGNTKFDALAAGPVPEDENLRTALGLTPGERVWIAG
STHEGEEAQLLGVYARLRERWPELRLVIAPRYVDRAARIVTLAREAGLSVGLRSQGNPERGQVVVLDTIGELSRAYRLAT
VVFVGGSFTTRGGQNILEPAGQGKPVLYGPHMDNFRDSVALLTGQGGLQVQDAAALEQALVSLLESPERLASLGAQALET
VGRISGASERNAEAMTTLFPHGRPDPR

Sequences:

>Translated_427_residues
MRVLYVLVTYLLFAVLFPVLALHRKTRHGLMERLGFYGPHSHLPPGDGPVLWLHGASAGDLLALSPMFGPLRARFPGCRL
LLSTMTDSGYAMAKGRLANDIDGVVYVPYDLWGATRRAVRAIRPDVLVLEYTEIWPNLIRAAKRGGARVVMTNGRFSPAN
VGKYQTLFRLIGNPLRDLDLLLMREEDEAVRARQLGARPDWVKVTGNTKFDALAAGPVPEDENLRTALGLTPGERVWIAG
STHEGEEAQLLGVYARLRERWPELRLVIAPRYVDRAARIVTLAREAGLSVGLRSQGNPERGQVVVLDTIGELSRAYRLAT
VVFVGGSFTTRGGQNILEPAGQGKPVLYGPHMDNFRDSVALLTGQGGLQVQDAAALEQALVSLLESPERLASLGAQALET
VGRISGASERNAEAMTTLFPHGRPDPR
>Mature_427_residues
MRVLYVLVTYLLFAVLFPVLALHRKTRHGLMERLGFYGPHSHLPPGDGPVLWLHGASAGDLLALSPMFGPLRARFPGCRL
LLSTMTDSGYAMAKGRLANDIDGVVYVPYDLWGATRRAVRAIRPDVLVLEYTEIWPNLIRAAKRGGARVVMTNGRFSPAN
VGKYQTLFRLIGNPLRDLDLLLMREEDEAVRARQLGARPDWVKVTGNTKFDALAAGPVPEDENLRTALGLTPGERVWIAG
STHEGEEAQLLGVYARLRERWPELRLVIAPRYVDRAARIVTLAREAGLSVGLRSQGNPERGQVVVLDTIGELSRAYRLAT
VVFVGGSFTTRGGQNILEPAGQGKPVLYGPHMDNFRDSVALLTGQGGLQVQDAAALEQALVSLLESPERLASLGAQALET
VGRISGASERNAEAMTTLFPHGRPDPR

Specific function: Essential step in lipopolysaccharides biosynthesis. Acts at transfer of 3-deoxy-D-mono octulonic acid (KDO) from CMP-KDO to a tetraacyldisaccharide 1,4'-bisphosphate precursor of lipid A (lipid IVA). Transfers two molecules of KDO to lipid IVA [H]

COG id: COG1519

COG function: function code M; 3-deoxy-D-manno-octulosonic-acid transferase

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 1 family [H]

Homologues:

Organism=Escherichia coli, GI1790064, Length=392, Percent_Identity=35.969387755102, Blast_Score=218, Evalue=4e-58,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001296
- InterPro:   IPR007507 [H]

Pfam domain/function: PF00534 Glycos_transf_1; PF04413 Glycos_transf_N [H]

EC number: 2.-.-.-

Molecular weight: Translated: 46628; Mature: 46628

Theoretical pI: Translated: 9.85; Mature: 9.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVLYVLVTYLLFAVLFPVLALHRKTRHGLMERLGFYGPHSHLPPGDGPVLWLHGASAGD
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEECCCCCC
LLALSPMFGPLRARFPGCRLLLSTMTDSGYAMAKGRLANDIDGVVYVPYDLWGATRRAVR
EEEECCCCCHHHHCCCHHHHHHHHHCCCCCEEECCCCCCCCCCEEEECHHHHHHHHHHHH
AIRPDVLVLEYTEIWPNLIRAAKRGGARVVMTNGRFSPANVGKYQTLFRLIGNPLRDLDL
HCCCCEEEEEHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCHHHHHHHHHHCCCHHCCCE
LLMREEDEAVRARQLGARPDWVKVTGNTKFDALAAGPVPEDENLRTALGLTPGERVWIAG
EEECCCHHHHHHHHCCCCCCEEEEECCCCCCEEECCCCCCCCCCEEEECCCCCCEEEEEC
STHEGEEAQLLGVYARLRERWPELRLVIAPRYVDRAARIVTLAREAGLSVGLRSQGNPER
CCCCCCHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHCCCEEECCCCCCCCC
GQVVVLDTIGELSRAYRLATVVFVGGSFTTRGGQNILEPAGQGKPVLYGPHMDNFRDSVA
CCEEEEECHHHHHHHHHEEEEEEECCCEECCCCCHHHCCCCCCCCEEECCCCCCCCCCEE
LLTGQGGLQVQDAAALEQALVSLLESPERLASLGAQALETVGRISGASERNAEAMTTLFP
EEECCCCCEEHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHCCC
HGRPDPR
CCCCCCC
>Mature Secondary Structure
MRVLYVLVTYLLFAVLFPVLALHRKTRHGLMERLGFYGPHSHLPPGDGPVLWLHGASAGD
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEECCCCCC
LLALSPMFGPLRARFPGCRLLLSTMTDSGYAMAKGRLANDIDGVVYVPYDLWGATRRAVR
EEEECCCCCHHHHCCCHHHHHHHHHCCCCCEEECCCCCCCCCCEEEECHHHHHHHHHHHH
AIRPDVLVLEYTEIWPNLIRAAKRGGARVVMTNGRFSPANVGKYQTLFRLIGNPLRDLDL
HCCCCEEEEEHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCHHHHHHHHHHCCCHHCCCE
LLMREEDEAVRARQLGARPDWVKVTGNTKFDALAAGPVPEDENLRTALGLTPGERVWIAG
EEECCCHHHHHHHHCCCCCCEEEEECCCCCCEEECCCCCCCCCCEEEECCCCCCEEEEEC
STHEGEEAQLLGVYARLRERWPELRLVIAPRYVDRAARIVTLAREAGLSVGLRSQGNPER
CCCCCCHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHCCCEEECCCCCCCCC
GQVVVLDTIGELSRAYRLATVVFVGGSFTTRGGQNILEPAGQGKPVLYGPHMDNFRDSVA
CCEEEEECHHHHHHHHHEEEEEEECCCEECCCCCHHHCCCCCCCCEEECCCCCCCCCCEE
LLTGQGGLQVQDAAALEQALVSLLESPERLASLGAQALETVGRISGASERNAEAMTTLFP
EEECCCCCEEHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHCCC
HGRPDPR
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Transferring phosphorus-containing groups [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]