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The map label for this gene is hisC [H]

Identifier: 108761881

GI number: 108761881

Start: 4946142

End: 4947233

Strand: Reverse

Name: hisC [H]

Synonym: MXAN_4038

Alternate gene names: 108761881

Gene position: 4947233-4946142 (Counterclockwise)

Preceding gene: 108761085

Following gene: 108760989

Centisome position: 54.13

GC content: 68.68

Gene sequence:

>1092_bases
ATGCGACCGCTCGTCCCCACCCACGTTGAGACGCTCAAGCCGTACGTGCCCGGCAAGCCCATTGAAGAGACCGAGCGTGA
GTTCGGCCTCAAGGGCGTCATCAAGCTGGCCTCGAACGAAAACCCACTGGGGCCCTCCCCGCGCGCCGTGGAGGCCATGC
GGAACGTCTCTGGCGCGACGCACCTGTACCCCGACGCCACGTCCTTCCACCTGGTGCGCAAGCTGGCCGCGCACGTGGAC
GTGAAGCCGGAGCAGGTGGTGCTGGGCAGCGGCTCCAACGAACTCATCGAGCTGCTCATCCGCACCTTCACCACGCCGGA
GGATGAAATCCTCCTGTGCCAGGGCTCCTTCTCCGCGTACCGCATCTCCGCGCAGGCCCATGGGCGGCCCTTCGTGGAGA
TGCCCATGCGCGAGGGCTTCCTGTACGACCTGGAGGCCATGGCGAAGGCCATCACCCCGCGCACGCGGATGGTGTTCCTG
GCCAACCCGGACAACCCCACGGGCACCGCGTTCAGCCGCGACGCCCTGACGCGCTTCCTGGCCGCGGTGCCGCCGGAGGT
GCTGGTGGTGCACGACGAGGCCTACTGCGAGTTCGTCGAGTGGCCCGAGTACACCAGCGCCGTGCCGCTGGTCGGCCAGC
ACCCGAACCTGGTGGCGCTGCGCACCTTCAGCAAGATTCACGGGCTGGCGGGCGTGCGCCTGGGCTATGGCATCATGGAT
GCCCGGCTGGCGGCGTACCTGCACCGCACGCGCATGCCCTTCAACCTGACGGTGCTGGCCCAGGCCGCGGGTCTGGCGGC
CCTGGAGGACACCGAGCACGTGCGCCGCACGCGTGAGGTGAACCGCGCGGGTCTGGACTACTTCGCCGCGGAGTTGCCGA
TGCTGGGCGGCACGCTCACGCACAGCCACGCCAACTTCGTGTTCGTGGACTTCGGCCGTCCCGCAGTGGCGCTGTACGAG
CAGCTGCTGCGCAAGGGCATCATCGTCCGGCCCTTCGCGGGGCAGGGGTTCCCGAACCACGTGCGCATCTCCGTGGGCAC
GCCCGCGGAGAACGCGCGCTGCGTCCAGGTGCTGAAAGAGATCCTGACATGA

Upstream 100 bases:

>100_bases
AGCTGTCGCCCGATGAACTGGTCCAGGACCGGTACGCGAAGTTTCGCGCGCTCGGTGTGTTCTCCGGACGCTGAATCCAC
CGTATCAGGGCCCTTACACC

Downstream 100 bases:

>100_bases
GCGCCCGGCCCTTCATCGTCGCCATCGACGGCCCCGCGGGCGCCGGCAAGTCCTCGGTGTCCAAGCTTCTGGCGCGCCGG
CTGGGCTTCTCGCTGGTGGA

Product: histidinol-phosphate aminotransferase

Products: NA

Alternate protein names: Imidazole acetol-phosphate transaminase [H]

Number of amino acids: Translated: 363; Mature: 363

Protein sequence:

>363_residues
MRPLVPTHVETLKPYVPGKPIEETEREFGLKGVIKLASNENPLGPSPRAVEAMRNVSGATHLYPDATSFHLVRKLAAHVD
VKPEQVVLGSGSNELIELLIRTFTTPEDEILLCQGSFSAYRISAQAHGRPFVEMPMREGFLYDLEAMAKAITPRTRMVFL
ANPDNPTGTAFSRDALTRFLAAVPPEVLVVHDEAYCEFVEWPEYTSAVPLVGQHPNLVALRTFSKIHGLAGVRLGYGIMD
ARLAAYLHRTRMPFNLTVLAQAAGLAALEDTEHVRRTREVNRAGLDYFAAELPMLGGTLTHSHANFVFVDFGRPAVALYE
QLLRKGIIVRPFAGQGFPNHVRISVGTPAENARCVQVLKEILT

Sequences:

>Translated_363_residues
MRPLVPTHVETLKPYVPGKPIEETEREFGLKGVIKLASNENPLGPSPRAVEAMRNVSGATHLYPDATSFHLVRKLAAHVD
VKPEQVVLGSGSNELIELLIRTFTTPEDEILLCQGSFSAYRISAQAHGRPFVEMPMREGFLYDLEAMAKAITPRTRMVFL
ANPDNPTGTAFSRDALTRFLAAVPPEVLVVHDEAYCEFVEWPEYTSAVPLVGQHPNLVALRTFSKIHGLAGVRLGYGIMD
ARLAAYLHRTRMPFNLTVLAQAAGLAALEDTEHVRRTREVNRAGLDYFAAELPMLGGTLTHSHANFVFVDFGRPAVALYE
QLLRKGIIVRPFAGQGFPNHVRISVGTPAENARCVQVLKEILT
>Mature_363_residues
MRPLVPTHVETLKPYVPGKPIEETEREFGLKGVIKLASNENPLGPSPRAVEAMRNVSGATHLYPDATSFHLVRKLAAHVD
VKPEQVVLGSGSNELIELLIRTFTTPEDEILLCQGSFSAYRISAQAHGRPFVEMPMREGFLYDLEAMAKAITPRTRMVFL
ANPDNPTGTAFSRDALTRFLAAVPPEVLVVHDEAYCEFVEWPEYTSAVPLVGQHPNLVALRTFSKIHGLAGVRLGYGIMD
ARLAAYLHRTRMPFNLTVLAQAAGLAALEDTEHVRRTREVNRAGLDYFAAELPMLGGTLTHSHANFVFVDFGRPAVALYE
QLLRKGIIVRPFAGQGFPNHVRISVGTPAENARCVQVLKEILT

Specific function: Histidine biosynthesis; seventh step. [C]

COG id: COG0079

COG function: function code E; Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788332, Length=363, Percent_Identity=29.2011019283747, Blast_Score=132, Evalue=4e-32,
Organism=Escherichia coli, GI1788627, Length=254, Percent_Identity=26.7716535433071, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1788722, Length=343, Percent_Identity=25.0728862973761, Blast_Score=65, Evalue=7e-12,
Organism=Saccharomyces cerevisiae, GI6322075, Length=402, Percent_Identity=30.0995024875622, Blast_Score=127, Evalue=3e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR005861
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.9 [H]

Molecular weight: Translated: 40038; Mature: 40038

Theoretical pI: Translated: 7.45; Mature: 7.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRPLVPTHVETLKPYVPGKPIEETEREFGLKGVIKLASNENPLGPSPRAVEAMRNVSGAT
CCCCCCCHHHHHCCCCCCCCHHHHHHHCCCCEEEEECCCCCCCCCCHHHHHHHHHCCCCC
HLYPDATSFHLVRKLAAHVDVKPEQVVLGSGSNELIELLIRTFTTPEDEILLCQGSFSAY
EECCCCHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHCCCCCCEEEEECCCCEE
RISAQAHGRPFVEMPMREGFLYDLEAMAKAITPRTRMVFLANPDNPTGTAFSRDALTRFL
EEEEHHCCCCCEECCCCCCCEECHHHHHHHCCCCEEEEEEECCCCCCCCCCCHHHHHHHH
AAVPPEVLVVHDEAYCEFVEWPEYTSAVPLVGQHPNLVALRTFSKIHGLAGVRLGYGIMD
HHCCCCEEEEECHHHHHHHCCCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHCCHHHH
ARLAAYLHRTRMPFNLTVLAQAAGLAALEDTEHVRRTREVNRAGLDYFAAELPMLGGTLT
HHHHHHHHHHCCCCEEEEEEHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEE
HSHANFVFVDFGRPAVALYEQLLRKGIIVRPFAGQGFPNHVRISVGTPAENARCVQVLKE
ECCCCEEEEECCCCHHHHHHHHHHCCEEEEECCCCCCCCEEEEEECCCCCCHHHHHHHHH
ILT
HHC
>Mature Secondary Structure
MRPLVPTHVETLKPYVPGKPIEETEREFGLKGVIKLASNENPLGPSPRAVEAMRNVSGAT
CCCCCCCHHHHHCCCCCCCCHHHHHHHCCCCEEEEECCCCCCCCCCHHHHHHHHHCCCCC
HLYPDATSFHLVRKLAAHVDVKPEQVVLGSGSNELIELLIRTFTTPEDEILLCQGSFSAY
EECCCCHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHCCCCCCEEEEECCCCEE
RISAQAHGRPFVEMPMREGFLYDLEAMAKAITPRTRMVFLANPDNPTGTAFSRDALTRFL
EEEEHHCCCCCEECCCCCCCEECHHHHHHHCCCCEEEEEEECCCCCCCCCCCHHHHHHHH
AAVPPEVLVVHDEAYCEFVEWPEYTSAVPLVGQHPNLVALRTFSKIHGLAGVRLGYGIMD
HHCCCCEEEEECHHHHHHHCCCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHCCHHHH
ARLAAYLHRTRMPFNLTVLAQAAGLAALEDTEHVRRTREVNRAGLDYFAAELPMLGGTLT
HHHHHHHHHHCCCCEEEEEEHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEE
HSHANFVFVDFGRPAVALYEQLLRKGIIVRPFAGQGFPNHVRISVGTPAENARCVQVLKE
ECCCCEEEEECCCCHHHHHHHHHHCCEEEEECCCCCCCCEEEEEECCCCCCHHHHHHHHH
ILT
HHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA