Click here to switch to the map view.

The map label for this gene is asnC

Identifier: 108761851

GI number: 108761851

Start: 2671512

End: 2672912

Strand: Direct

Name: asnC

Synonym: MXAN_2298

Alternate gene names: 108761851

Gene position: 2671512-2672912 (Clockwise)

Preceding gene: 108762361

Following gene: 108763130

Centisome position: 29.23

GC content: 65.17

Gene sequence:

>1401_bases
ATGCAGGTCGTCAGTGTGAAGAAGGCCCTCGCGGGAGGGGTGGAGGAGGGGACGAAGGTGGAGGTCCGCGGCTGGGTGCG
CACGCGCCGCGACTCCAAGGCGGGCATCAGCTTCGTCAACGTCAGCGACGGGTCGACGTTCGACCCCATCCAGGTCGTCG
CTCCGAATTCGCTGCCCAACTACGAGAAGGAAATCCTGCACCTCACCGCGGGCTGCTCGGTCATCAGCCGGGGCACGCTG
GTGAAGTCCCAGGGCAAGGGGCAGGCCTATGAAGTCCAGGCGGACGAAGTCCAGGTGCTGGGCTTCGTGGACGACCCGGA
CACGTACCCCATCCAGCCCAAGCAGCACACGCTGGAGTTCCTGCGCGACGTGGCCCACCTGCGCGTGCGCACCAACACGT
TCAGCGCCGTCACGCGCGTGCGGCACCGCGCCGCCCAGGCCGTCCACCGCTTCTTCGACGAGGAGGGCTTCTTCTGGGTC
AACACGCCCATCATCACCGCGAGCGACGCGGAGGGCGCCGGGCAGATGTTCCGCGTCTCCACGCTGGACGCGGTGAATCC
GCCGCGCACGTCGGACGGGAAGATTGACTGGCACAAGGACTTCTTCGGCAAGGAGGCGTACCTGACCGTCTCTGGCCAGC
TCAACGCGGAGGCCTACGCCCTGGCTATGTCCAAGGTGTACACGTTCGGCCCCACGTTCCGGGCGGAGAACTCCAACACC
ACGCGGCACCTGGCCGAGTTCTGGATGATCGAGCCGGAGGTTGCCTTCGCGGACCTCAACGAGGACGCGAACCTGGCCGA
GCGCTTCCTCAAGCATGTCTTCAAGGCGGTGCTCAATGACTGTGCGCCGGACCTGAAGTTCTTCGAGGAGCGGGTGCAGA
AAGGCGTCATCGAGCGCATGGAGAAGTTCATCAACTCCAGCTTCGAGCGCATCGACTACACCGAGGCCGTCGAAATCCTG
AAGAAGGCCAAGAAGAAGTTCGAGTTCGAGCCCGAGTGGGGCAAGGACCTCCAGACGGAGCACGAGCGCTATCTCACCGA
GGAGCACGTGGGCCGGCCGGTGGTGGTGATGAACTACCCGGAGGCCATCAAGTCCTTCTACATGCGCCTGAACGATGACG
GGAAGACGGTCGCCGCCATGGACGTGCTCGCCCCGGGCATTGGCGAAATCATCGGCGGCAGCCAGCGCGAGGAGCGCCTG
GATGTGCTGGATCAGCGCATCCAGAAGTTCGGCCTGAAGCCGGAGAGCTACCAGTGGTACCGCGACCTGCGGCGCTACGG
CTCCGTGCCACACGCGGGCTTCGGGCTCGGCTTCGAGCGGCTCATCGTCTACATGTGCGGTCTGCAGAACATCCGGGACG
CGATTCCCTACCCGCGCGTGCCGGGCTCCGCGGCGTTCTAA

Upstream 100 bases:

>100_bases
GGGCGGCCAGGGCGGCGAGGCTTGGGGCACAGCGCCCTTGTCCTCGGGGCCGGGGCCCGGCTAACTCGCAGTCCCCGAAA
CGGCTCAAGGGAGAGCGTCA

Downstream 100 bases:

>100_bases
ACCGCCGTCCGAGTGTCCCCTCCACCGAGGGAGGGGACACCCGCCCGTTCAGGGCAACTGGCTCTCCAGCGCGTCCCAGC
GGGTCCGAATCCACTGGCGC

Product: asparaginyl-tRNA synthetase

Products: NA

Alternate protein names: Asparagine--tRNA ligase; AsnRS

Number of amino acids: Translated: 466; Mature: 466

Protein sequence:

>466_residues
MQVVSVKKALAGGVEEGTKVEVRGWVRTRRDSKAGISFVNVSDGSTFDPIQVVAPNSLPNYEKEILHLTAGCSVISRGTL
VKSQGKGQAYEVQADEVQVLGFVDDPDTYPIQPKQHTLEFLRDVAHLRVRTNTFSAVTRVRHRAAQAVHRFFDEEGFFWV
NTPIITASDAEGAGQMFRVSTLDAVNPPRTSDGKIDWHKDFFGKEAYLTVSGQLNAEAYALAMSKVYTFGPTFRAENSNT
TRHLAEFWMIEPEVAFADLNEDANLAERFLKHVFKAVLNDCAPDLKFFEERVQKGVIERMEKFINSSFERIDYTEAVEIL
KKAKKKFEFEPEWGKDLQTEHERYLTEEHVGRPVVVMNYPEAIKSFYMRLNDDGKTVAAMDVLAPGIGEIIGGSQREERL
DVLDQRIQKFGLKPESYQWYRDLRRYGSVPHAGFGLGFERLIVYMCGLQNIRDAIPYPRVPGSAAF

Sequences:

>Translated_466_residues
MQVVSVKKALAGGVEEGTKVEVRGWVRTRRDSKAGISFVNVSDGSTFDPIQVVAPNSLPNYEKEILHLTAGCSVISRGTL
VKSQGKGQAYEVQADEVQVLGFVDDPDTYPIQPKQHTLEFLRDVAHLRVRTNTFSAVTRVRHRAAQAVHRFFDEEGFFWV
NTPIITASDAEGAGQMFRVSTLDAVNPPRTSDGKIDWHKDFFGKEAYLTVSGQLNAEAYALAMSKVYTFGPTFRAENSNT
TRHLAEFWMIEPEVAFADLNEDANLAERFLKHVFKAVLNDCAPDLKFFEERVQKGVIERMEKFINSSFERIDYTEAVEIL
KKAKKKFEFEPEWGKDLQTEHERYLTEEHVGRPVVVMNYPEAIKSFYMRLNDDGKTVAAMDVLAPGIGEIIGGSQREERL
DVLDQRIQKFGLKPESYQWYRDLRRYGSVPHAGFGLGFERLIVYMCGLQNIRDAIPYPRVPGSAAF
>Mature_466_residues
MQVVSVKKALAGGVEEGTKVEVRGWVRTRRDSKAGISFVNVSDGSTFDPIQVVAPNSLPNYEKEILHLTAGCSVISRGTL
VKSQGKGQAYEVQADEVQVLGFVDDPDTYPIQPKQHTLEFLRDVAHLRVRTNTFSAVTRVRHRAAQAVHRFFDEEGFFWV
NTPIITASDAEGAGQMFRVSTLDAVNPPRTSDGKIDWHKDFFGKEAYLTVSGQLNAEAYALAMSKVYTFGPTFRAENSNT
TRHLAEFWMIEPEVAFADLNEDANLAERFLKHVFKAVLNDCAPDLKFFEERVQKGVIERMEKFINSSFERIDYTEAVEIL
KKAKKKFEFEPEWGKDLQTEHERYLTEEHVGRPVVVMNYPEAIKSFYMRLNDDGKTVAAMDVLAPGIGEIIGGSQREERL
DVLDQRIQKFGLKPESYQWYRDLRRYGSVPHAGFGLGFERLIVYMCGLQNIRDAIPYPRVPGSAAF

Specific function: Unknown

COG id: COG0017

COG function: function code J; Aspartyl/asparaginyl-tRNA synthetases

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family

Homologues:

Organism=Homo sapiens, GI226491502, Length=465, Percent_Identity=44.7311827956989, Blast_Score=405, Evalue=1e-113,
Organism=Homo sapiens, GI4758762, Length=451, Percent_Identity=28.159645232816, Blast_Score=186, Evalue=5e-47,
Organism=Homo sapiens, GI45439306, Length=345, Percent_Identity=28.9855072463768, Blast_Score=123, Evalue=5e-28,
Organism=Escherichia coli, GI1787161, Length=466, Percent_Identity=66.9527896995708, Blast_Score=664, Evalue=0.0,
Organism=Escherichia coli, GI1790571, Length=469, Percent_Identity=22.8144989339019, Blast_Score=62, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI71984122, Length=454, Percent_Identity=30.6167400881057, Blast_Score=202, Evalue=3e-52,
Organism=Caenorhabditis elegans, GI17556372, Length=424, Percent_Identity=32.0754716981132, Blast_Score=199, Evalue=3e-51,
Organism=Caenorhabditis elegans, GI17551876, Length=348, Percent_Identity=28.1609195402299, Blast_Score=111, Evalue=7e-25,
Organism=Saccharomyces cerevisiae, GI6319872, Length=474, Percent_Identity=37.5527426160338, Blast_Score=308, Evalue=2e-84,
Organism=Saccharomyces cerevisiae, GI6321807, Length=457, Percent_Identity=32.3851203501094, Blast_Score=211, Evalue=3e-55,
Organism=Saccharomyces cerevisiae, GI6323011, Length=344, Percent_Identity=29.0697674418605, Blast_Score=123, Evalue=7e-29,
Organism=Drosophila melanogaster, GI19922416, Length=457, Percent_Identity=34.5733041575492, Blast_Score=272, Evalue=4e-73,
Organism=Drosophila melanogaster, GI19921528, Length=464, Percent_Identity=29.3103448275862, Blast_Score=190, Evalue=2e-48,
Organism=Drosophila melanogaster, GI17136276, Length=394, Percent_Identity=27.6649746192893, Blast_Score=112, Evalue=5e-25,

Paralogues:

None

Copy number: 80 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): SYN_MYXXD (Q1DA04)

Other databases:

- EMBL:   CP000113
- RefSeq:   YP_630519.1
- ProteinModelPortal:   Q1DA04
- SMR:   Q1DA04
- STRING:   Q1DA04
- GeneID:   4105595
- GenomeReviews:   CP000113_GR
- KEGG:   mxa:MXAN_2298
- TIGR:   MXAN_2298
- eggNOG:   COG0017
- HOGENOM:   HBG745843
- OMA:   EPEMAFC
- PhylomeDB:   Q1DA04
- ProtClustDB:   PRK03932
- BioCyc:   MXAN246197:MXAN_2298-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00534
- InterPro:   IPR004364
- InterPro:   IPR018150
- InterPro:   IPR006195
- InterPro:   IPR004522
- InterPro:   IPR002312
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR004365
- Gene3D:   G3DSA:2.40.50.140
- PANTHER:   PTHR22594
- PRINTS:   PR01042
- TIGRFAMs:   TIGR00457

Pfam domain/function: PF00152 tRNA-synt_2; PF01336 tRNA_anti; SSF50249 Nucleic_acid_OB

EC number: =6.1.1.22

Molecular weight: Translated: 52753; Mature: 52753

Theoretical pI: Translated: 6.31; Mature: 6.31

Prosite motif: PS50862 AA_TRNA_LIGASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQVVSVKKALAGGVEEGTKVEVRGWVRTRRDSKAGISFVNVSDGSTFDPIQVVAPNSLPN
CCCHHHHHHHHCCCCCCCEEEEEHHHHHCCCCCCCEEEEEECCCCCCCCEEEECCCCCCC
YEKEILHLTAGCSVISRGTLVKSQGKGQAYEVQADEVQVLGFVDDPDTYPIQPKQHTLEF
HHHHHHHHHHCCHHHHCCCEEECCCCCCEEEEECCCEEEEEEECCCCCCCCCCHHHHHHH
LRDVAHLRVRTNTFSAVTRVRHRAAQAVHRFFDEEGFFWVNTPIITASDAEGAGQMFRVS
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCEEEECCCCCCCCEEEEE
TLDAVNPPRTSDGKIDWHKDFFGKEAYLTVSGQLNAEAYALAMSKVYTFGPTFRAENSNT
ECCCCCCCCCCCCCCEECHHHCCCEEEEEEECCCCCHHHHHHHHHHHHCCCCEECCCCCH
TRHLAEFWMIEPEVAFADLNEDANLAERFLKHVFKAVLNDCAPDLKFFEERVQKGVIERM
HHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
EKFINSSFERIDYTEAVEILKKAKKKFEFEPEWGKDLQTEHERYLTEEHVGRPVVVMNYP
HHHHCCHHHHCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEECCH
EAIKSFYMRLNDDGKTVAAMDVLAPGIGEIIGGSQREERLDVLDQRIQKFGLKPESYQWY
HHHHHHHHHCCCCCCEEEHHHHHCCCHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCHHHH
RDLRRYGSVPHAGFGLGFERLIVYMCGLQNIRDAIPYPRVPGSAAF
HHHHHHCCCCCCCCCCCHHHHHHHHHCHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MQVVSVKKALAGGVEEGTKVEVRGWVRTRRDSKAGISFVNVSDGSTFDPIQVVAPNSLPN
CCCHHHHHHHHCCCCCCCEEEEEHHHHHCCCCCCCEEEEEECCCCCCCCEEEECCCCCCC
YEKEILHLTAGCSVISRGTLVKSQGKGQAYEVQADEVQVLGFVDDPDTYPIQPKQHTLEF
HHHHHHHHHHCCHHHHCCCEEECCCCCCEEEEECCCEEEEEEECCCCCCCCCCHHHHHHH
LRDVAHLRVRTNTFSAVTRVRHRAAQAVHRFFDEEGFFWVNTPIITASDAEGAGQMFRVS
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCEEEECCCCCCCCEEEEE
TLDAVNPPRTSDGKIDWHKDFFGKEAYLTVSGQLNAEAYALAMSKVYTFGPTFRAENSNT
ECCCCCCCCCCCCCCEECHHHCCCEEEEEEECCCCCHHHHHHHHHHHHCCCCEECCCCCH
TRHLAEFWMIEPEVAFADLNEDANLAERFLKHVFKAVLNDCAPDLKFFEERVQKGVIERM
HHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
EKFINSSFERIDYTEAVEILKKAKKKFEFEPEWGKDLQTEHERYLTEEHVGRPVVVMNYP
HHHHCCHHHHCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEECCH
EAIKSFYMRLNDDGKTVAAMDVLAPGIGEIIGGSQREERLDVLDQRIQKFGLKPESYQWY
HHHHHHHHHCCCCCCEEEHHHHHCCCHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCHHHH
RDLRRYGSVPHAGFGLGFERLIVYMCGLQNIRDAIPYPRVPGSAAF
HHHHHHCCCCCCCCCCCHHHHHHHHHCHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA