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The map label for this gene is tig [H]

Identifier: 108761808

GI number: 108761808

Start: 2033033

End: 2034127

Strand: Reverse

Name: tig [H]

Synonym: MXAN_1713

Alternate gene names: 108761808

Gene position: 2034127-2033033 (Counterclockwise)

Preceding gene: 108761941

Following gene: 108757711

Centisome position: 22.26

GC content: 66.58

Gene sequence:

>1095_bases
ATGCACTCGCCTCCTGACAAGTCCAACCCAGGCCAGCCGCTCTCGATTGGGGAGTTGCAGGGCATGGGGCTGTTGAACCA
AGCGCCCGGAGCGATGGCCTTCCGCAATGCGACGAGCCCTCGACTTCCGCTCCTCCGCGAGGCCCCTTCGCTGGAGGAGC
TCCGGGTGAAGATGCCGGAGCTCGGGGGAATTTCGCCCGAGGCCATCCTTGATCGCTTCGCCACGCTATGCCGCGTGGTG
GCGCCGCGCAGGGAGCGCGAGCCGGGCGAAGCCGTTGACTCCGGAGACGACGTGCTCCTGGACGTCGTCGGCTTCGCCAA
CGGAAGGCTCATCCCGTTCTCCGCCCGCGCGGAATGGAGGACGGAAGCCACTCCCGACCCGCTGCTCCCCGGCTTCTTCG
AAGCCGTGGTGCGGGCCCGGGTTGGCGAGTCCGTAGCGGTGGACCTCGTCCTGCCTGATGACTACGCAGTGGAGTCCCTT
CGTGGCGTCCCTGCTCGCTTCGACGTGAAGATGAAGGCGGCCTACCAGGTGACGCTACTGGGGGAGTCATCTCCAGAACT
CTTCGCCGCGCTGGGACGCGGAGGCACGCTCGACGAGGTCATGGAGTACATCGCCGGGGAACTCATCGCCCAGCGGGACG
CGCAGTACCTGTGGGACTTCCAGGACCACGTGATGAGGGAGGTGGCTCGGCGCACGCATGTCGAGGTGCCACGGAGCCTC
ATCGACGAAGAAATCCGCCAGCGGTGGGCCGAGGCCGAGTATCCAATCCTGGTGAGCCTGGGCCTACCGCACGAGCGGGT
CCGGGAAGGACTGGATGGCTGGCTGCTCGACGACTCCACCCGGAGCGAACTGGAGTACCGGCTGCGGCTGGCGCTTGGGC
TTCGGGCCATCGCCGAAAGAGACCACATCCAGTCCGAGCGGGAGTCCGCGGAGGAGCTGTTCAACAGCCTCGCGGAGAGA
GCCCAACTGAGCCGCGTTGAGCTGGGGCGCCTGCTCCAGTCCGACAAGAATCTCGGCCGGAGGTTCGACACGCTGACGAT
GCACACGGCGGTCGTCAGCCACATCCTGTCCAAGGCCGACGTTTCGCGGGAGTAA

Upstream 100 bases:

>100_bases
GTCCGTGCTCGCGGCCACGAACATCCCGGTGGTGAGTCAGGTCGGCGCGGCCTTCTCCACAGTCTCCGACCTCGTCGGGA
GCTTCTTCTAGGAGCCCTCC

Downstream 100 bases:

>100_bases
TGGCAAGGCCATGGGCCCGCGGTCGTAGGGAGAAGGCGCGCGGCTCGAAGAATGGGGGCAGAGCAGTGCCCATGGCTCCC
CACTTCGAGCCGCGCTGTCA

Product: peptidyl-prolyl cis-trans isomerase domain-containing protein

Products: peptidylproline (omega=0)

Alternate protein names: TF [H]

Number of amino acids: Translated: 364; Mature: 364

Protein sequence:

>364_residues
MHSPPDKSNPGQPLSIGELQGMGLLNQAPGAMAFRNATSPRLPLLREAPSLEELRVKMPELGGISPEAILDRFATLCRVV
APRREREPGEAVDSGDDVLLDVVGFANGRLIPFSARAEWRTEATPDPLLPGFFEAVVRARVGESVAVDLVLPDDYAVESL
RGVPARFDVKMKAAYQVTLLGESSPELFAALGRGGTLDEVMEYIAGELIAQRDAQYLWDFQDHVMREVARRTHVEVPRSL
IDEEIRQRWAEAEYPILVSLGLPHERVREGLDGWLLDDSTRSELEYRLRLALGLRAIAERDHIQSERESAEELFNSLAER
AQLSRVELGRLLQSDKNLGRRFDTLTMHTAVVSHILSKADVSRE

Sequences:

>Translated_364_residues
MHSPPDKSNPGQPLSIGELQGMGLLNQAPGAMAFRNATSPRLPLLREAPSLEELRVKMPELGGISPEAILDRFATLCRVV
APRREREPGEAVDSGDDVLLDVVGFANGRLIPFSARAEWRTEATPDPLLPGFFEAVVRARVGESVAVDLVLPDDYAVESL
RGVPARFDVKMKAAYQVTLLGESSPELFAALGRGGTLDEVMEYIAGELIAQRDAQYLWDFQDHVMREVARRTHVEVPRSL
IDEEIRQRWAEAEYPILVSLGLPHERVREGLDGWLLDDSTRSELEYRLRLALGLRAIAERDHIQSERESAEELFNSLAER
AQLSRVELGRLLQSDKNLGRRFDTLTMHTAVVSHILSKADVSRE
>Mature_364_residues
MHSPPDKSNPGQPLSIGELQGMGLLNQAPGAMAFRNATSPRLPLLREAPSLEELRVKMPELGGISPEAILDRFATLCRVV
APRREREPGEAVDSGDDVLLDVVGFANGRLIPFSARAEWRTEATPDPLLPGFFEAVVRARVGESVAVDLVLPDDYAVESL
RGVPARFDVKMKAAYQVTLLGESSPELFAALGRGGTLDEVMEYIAGELIAQRDAQYLWDFQDHVMREVARRTHVEVPRSL
IDEEIRQRWAEAEYPILVSLGLPHERVREGLDGWLLDDSTRSELEYRLRLALGLRAIAERDHIQSERESAEELFNSLAER
AQLSRVELGRLLQSDKNLGRRFDTLTMHTAVVSHILSKADVSRE

Specific function: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation [H]

COG id: COG0544

COG function: function code O; FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PPIase FKBP-type domain [H]

Homologues:

None

Paralogues:

None

Copy number: 1070 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 300 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 500 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 340 Molecules/Cell In: Growth-Phase, Mini

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001179
- InterPro:   IPR005215
- InterPro:   IPR008880
- InterPro:   IPR008881 [H]

Pfam domain/function: PF00254 FKBP_C; PF05698 Trigger_C; PF05697 Trigger_N [H]

EC number: 5.2.1.8

Molecular weight: Translated: 40586; Mature: 40586

Theoretical pI: Translated: 4.78; Mature: 4.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHSPPDKSNPGQPLSIGELQGMGLLNQAPGAMAFRNATSPRLPLLREAPSLEELRVKMPE
CCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCCEECCCCCCCCCHHHCCCCHHHHHHHCCC
LGGISPEAILDRFATLCRVVAPRREREPGEAVDSGDDVLLDVVGFANGRLIPFSARAEWR
CCCCCHHHHHHHHHHHHHHHCCHHCCCCCCCCCCCCCEEHHHHHCCCCCEEEECCCCCCC
TEATPDPLLPGFFEAVVRARVGESVAVDLVLPDDYAVESLRGVPARFDVKMKAAYQVTLL
CCCCCCCCCHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHCCCCCCCCEEEEEEEEEEEE
GESSPELFAALGRGGTLDEVMEYIAGELIAQRDAQYLWDFQDHVMREVARRTHVEVPRSL
CCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IDEEIRQRWAEAEYPILVSLGLPHERVREGLDGWLLDDSTRSELEYRLRLALGLRAIAER
HHHHHHHHHHCCCCCEEEEECCCHHHHHCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHH
DHIQSERESAEELFNSLAERAQLSRVELGRLLQSDKNLGRRFDTLTMHTAVVSHILSKAD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VSRE
CCCC
>Mature Secondary Structure
MHSPPDKSNPGQPLSIGELQGMGLLNQAPGAMAFRNATSPRLPLLREAPSLEELRVKMPE
CCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCCEECCCCCCCCCHHHCCCCHHHHHHHCCC
LGGISPEAILDRFATLCRVVAPRREREPGEAVDSGDDVLLDVVGFANGRLIPFSARAEWR
CCCCCHHHHHHHHHHHHHHHCCHHCCCCCCCCCCCCCEEHHHHHCCCCCEEEECCCCCCC
TEATPDPLLPGFFEAVVRARVGESVAVDLVLPDDYAVESLRGVPARFDVKMKAAYQVTLL
CCCCCCCCCHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHCCCCCCCCEEEEEEEEEEEE
GESSPELFAALGRGGTLDEVMEYIAGELIAQRDAQYLWDFQDHVMREVARRTHVEVPRSL
CCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IDEEIRQRWAEAEYPILVSLGLPHERVREGLDGWLLDDSTRSELEYRLRLALGLRAIAER
HHHHHHHHHHCCCCCEEEEECCCHHHHHCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHH
DHIQSERESAEELFNSLAERAQLSRVELGRLLQSDKNLGRRFDTLTMHTAVVSHILSKAD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VSRE
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: peptidylproline (omega=180)

Specific reaction: peptidylproline (omega=180) = peptidylproline (omega=0)

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA