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The map label for this gene is ydfG [H]

Identifier: 108761786

GI number: 108761786

Start: 4829506

End: 4830366

Strand: Reverse

Name: ydfG [H]

Synonym: MXAN_3965

Alternate gene names: 108761786

Gene position: 4830366-4829506 (Counterclockwise)

Preceding gene: 108759720

Following gene: 108761964

Centisome position: 52.85

GC content: 70.85

Gene sequence:

>861_bases
ATGCGTCCTCTCCCCATCGACCAAGGAACCGTGCTGATCATCGGCGCGGCCCGGGGGATTGGCCGGGAGCTTGCCCGGCT
GCTTGCACGTCGCGTTCGGACCCTGGTGCTCGTGGACCATCAGGCCCAGGTCCTGGAGCCCCTGCGCGAGGAACTCCTGC
TGAACTACCCGACGCTGGGCGTGCTCGTCGAATCCTGCGACGTGTGCGATCCCCAGCAGGTGGACGCGCTGCTCGCTTCG
CTGGAGTCGCAGTTCGTCCGCGTGGACGTGTTGGTGAACAACGCCGCGGAAGGCGACCAGGCGCTGTATGCCCAGGAGGG
CTGGGGGCGTGTGGAAGCCATGTTGCGCGCCAACGTCTGGGTGCCCGCGCTGCTGACGCACCGGCTGCTCAAGCCCATGT
TGGAGCGTGGACGGGGCGGCATCCTCAACATCGGCTCCGGCGCGGCGCAGCTCATCCTGCCGGGCTCGGCCACCTTCTCC
GCCACCCAGCGCTTCCTGGACGGCTTCACGGAGGCGCTGCGCCTGGAGGTGGAGGGGCAGGGCGTCACGGTGACGCGCGT
AGCTCCGGGGCCGCTGTGGGAAGCGGGTGTGGAGGGCGCGGAGTCACTGGCGCCTTTCTTCCATCTGTCACTGGAGCGCT
GTGCCCGCGAGGCGCTCGCCGGCTTCGAGCGCGGCGCGGCCCTGGTGTACCCGGGCTTGGGGCACCGGTGGGTGATGCGG
CTGCTGCCACTGCTGCCACGCGGGCTCAAGCGGAGCCTGGGGCGGATGGCGCTGCGGGGCCTGCGGCGGGAGGAGTTGCT
GCTCCCACCACGGCAGGCCCCCCAGGCGCTGCCACTTTCGGGCGAGCCATCACCCGCGTGA

Upstream 100 bases:

>100_bases
CCGGTCGTCTGCTGTCCAGGCGTGCAAACCCTGCGGGGGGAGCGGCAGACCGCGCAAGGCATGCGCACGATGGGCACCTC
AACGAACGGAGGATTTTGTC

Downstream 100 bases:

>100_bases
CGCGGGGGCTCGGCTCTAGAGGCCAATCTCGGCCAGGCGCGCCTTCACGCGCGTGGCCTTCACGCCGGTGTTGGCCGTGC
CGCGGCCCTGCGAGTTGCCG

Product: short chain dehydrogenase/reductase family oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 286; Mature: 286

Protein sequence:

>286_residues
MRPLPIDQGTVLIIGAARGIGRELARLLARRVRTLVLVDHQAQVLEPLREELLLNYPTLGVLVESCDVCDPQQVDALLAS
LESQFVRVDVLVNNAAEGDQALYAQEGWGRVEAMLRANVWVPALLTHRLLKPMLERGRGGILNIGSGAAQLILPGSATFS
ATQRFLDGFTEALRLEVEGQGVTVTRVAPGPLWEAGVEGAESLAPFFHLSLERCAREALAGFERGAALVYPGLGHRWVMR
LLPLLPRGLKRSLGRMALRGLRREELLLPPRQAPQALPLSGEPSPA

Sequences:

>Translated_286_residues
MRPLPIDQGTVLIIGAARGIGRELARLLARRVRTLVLVDHQAQVLEPLREELLLNYPTLGVLVESCDVCDPQQVDALLAS
LESQFVRVDVLVNNAAEGDQALYAQEGWGRVEAMLRANVWVPALLTHRLLKPMLERGRGGILNIGSGAAQLILPGSATFS
ATQRFLDGFTEALRLEVEGQGVTVTRVAPGPLWEAGVEGAESLAPFFHLSLERCAREALAGFERGAALVYPGLGHRWVMR
LLPLLPRGLKRSLGRMALRGLRREELLLPPRQAPQALPLSGEPSPA
>Mature_286_residues
MRPLPIDQGTVLIIGAARGIGRELARLLARRVRTLVLVDHQAQVLEPLREELLLNYPTLGVLVESCDVCDPQQVDALLAS
LESQFVRVDVLVNNAAEGDQALYAQEGWGRVEAMLRANVWVPALLTHRLLKPMLERGRGGILNIGSGAAQLILPGSATFS
ATQRFLDGFTEALRLEVEGQGVTVTRVAPGPLWEAGVEGAESLAPFFHLSLERCAREALAGFERGAALVYPGLGHRWVMR
LLPLLPRGLKRSLGRMALRGLRREELLLPPRQAPQALPLSGEPSPA

Specific function: Catalyzes the NADP-dependent oxidation of L-allo- threonine and L-serine [H]

COG id: COG0300

COG function: function code R; Short-chain dehydrogenases of various substrate specificities

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI7705855, Length=186, Percent_Identity=30.1075268817204, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI7706318, Length=193, Percent_Identity=29.0155440414508, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI20149619, Length=189, Percent_Identity=27.5132275132275, Blast_Score=72, Evalue=7e-13,
Organism=Homo sapiens, GI40254992, Length=178, Percent_Identity=28.6516853932584, Blast_Score=68, Evalue=1e-11,
Organism=Escherichia coli, GI1787820, Length=184, Percent_Identity=30.4347826086957, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI1787335, Length=182, Percent_Identity=29.6703296703297, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI87082100, Length=182, Percent_Identity=28.5714285714286, Blast_Score=63, Evalue=3e-11,
Organism=Escherichia coli, GI2367175, Length=188, Percent_Identity=32.9787234042553, Blast_Score=62, Evalue=3e-11,
Organism=Escherichia coli, GI1786701, Length=189, Percent_Identity=28.5714285714286, Blast_Score=61, Evalue=7e-11,
Organism=Caenorhabditis elegans, GI25152911, Length=184, Percent_Identity=32.6086956521739, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17508895, Length=182, Percent_Identity=29.1208791208791, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17560176, Length=184, Percent_Identity=29.3478260869565, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17559552, Length=265, Percent_Identity=25.6603773584906, Blast_Score=70, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI17562908, Length=188, Percent_Identity=29.2553191489362, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17562906, Length=187, Percent_Identity=28.3422459893048, Blast_Score=65, Evalue=6e-11,
Organism=Saccharomyces cerevisiae, GI6323882, Length=187, Percent_Identity=27.2727272727273, Blast_Score=69, Evalue=7e-13,
Organism=Drosophila melanogaster, GI23397609, Length=187, Percent_Identity=31.0160427807487, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI21358495, Length=182, Percent_Identity=28.5714285714286, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI21355631, Length=167, Percent_Identity=29.3413173652695, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24580925, Length=193, Percent_Identity=33.160621761658, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI161076933, Length=186, Percent_Identity=29.5698924731183, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24584748, Length=186, Percent_Identity=29.5698924731183, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24584744, Length=187, Percent_Identity=28.3422459893048, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI28574402, Length=187, Percent_Identity=28.3422459893048, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI21357041, Length=184, Percent_Identity=27.1739130434783, Blast_Score=64, Evalue=1e-10,

Paralogues:

None

Copy number: 1300 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 31106; Mature: 31106

Theoretical pI: Translated: 8.09; Mature: 8.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRPLPIDQGTVLIIGAARGIGRELARLLARRVRTLVLVDHQAQVLEPLREELLLNYPTLG
CCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHEEECCHHHHHHHHHHHHHHCCCHHH
VLVESCDVCDPQQVDALLASLESQFVRVDVLVNNAAEGDQALYAQEGWGRVEAMLRANVW
HHHHHCCCCCHHHHHHHHHHHHHHHEEEEEEECCCCCCCHHHHHHCCHHHHHHHHHHCCC
VPALLTHRLLKPMLERGRGGILNIGSGAAQLILPGSATFSATQRFLDGFTEALRLEVEGQ
HHHHHHHHHHHHHHHHCCCCEEEECCCCEEEEECCCCHHHHHHHHHHHHHHHHEEEECCC
GVTVTRVAPGPLWEAGVEGAESLAPFFHLSLERCAREALAGFERGAALVYPGLGHRWVMR
CEEEEEECCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCHHHHHH
LLPLLPRGLKRSLGRMALRGLRREELLLPPRQAPQALPLSGEPSPA
HHHHCCHHHHHHHHHHHHHHCCHHHCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MRPLPIDQGTVLIIGAARGIGRELARLLARRVRTLVLVDHQAQVLEPLREELLLNYPTLG
CCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHEEECCHHHHHHHHHHHHHHCCCHHH
VLVESCDVCDPQQVDALLASLESQFVRVDVLVNNAAEGDQALYAQEGWGRVEAMLRANVW
HHHHHCCCCCHHHHHHHHHHHHHHHEEEEEEECCCCCCCHHHHHHCCHHHHHHHHHHCCC
VPALLTHRLLKPMLERGRGGILNIGSGAAQLILPGSATFSATQRFLDGFTEALRLEVEGQ
HHHHHHHHHHHHHHHHCCCCEEEECCCCEEEEECCCCHHHHHHHHHHHHHHHHEEEECCC
GVTVTRVAPGPLWEAGVEGAESLAPFFHLSLERCAREALAGFERGAALVYPGLGHRWVMR
CEEEEEECCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCHHHHHH
LLPLLPRGLKRSLGRMALRGLRREELLLPPRQAPQALPLSGEPSPA
HHHHCCHHHHHHHHHHHHHHCCHHHCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11677608; 12644504 [H]