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The map label for this gene is zraR [H]

Identifier: 108761717

GI number: 108761717

Start: 414440

End: 415900

Strand: Direct

Name: zraR [H]

Synonym: MXAN_0353

Alternate gene names: 108761717

Gene position: 414440-415900 (Clockwise)

Preceding gene: 108760368

Following gene: 108760670

Centisome position: 4.53

GC content: 64.68

Gene sequence:

>1461_bases
GTGGGGGGCCTTTGCTATCCTCGTGCGCAGATGAGTGCTCCCCCTCTGCACCCTGACGACATCCACACCAGTCCCGGCGA
CGTCGGACAAGACCTGAACCACTCTCCGTTGTTGGGCGAAACGCTCGTGGTGGACCCGCGCACCACGGTGAAGCTCCACA
AGTGCCGCCTGGCCGTCACCTCCGGACCGGACACCGGCCGCTCGGTGGTGAGCGACAAGGAGCGGCTGCGTTGCGGCGCG
CATCCAGGCAATGACCTGGTGCTGGTGGAGGACCGCACCGCCAGCCGTCACCACTTCGAAATCCAGTTCACCGAGCGCGG
CTATCTGCTGGTGGACCTGGGCTCCACCAACGGCACCTTCCTGGATGGCCGGCGCATCGAGCGGGCCTACCTGTCACCCG
GCTCGCAGATTCGCGCGGGCTCGTCGGTGCTGACCTTCGCGCCACTGGATGAGGAAGTCACCATCGAGCCCGACCGCGAG
GGCGAGCTGTGCGGCATGGTGGGGCAGAGCATGAAGATGCGGCAGATATTCGGCCTCATCAAGAAGATCGCCCCCATGGG
AGTGTCCGTCATCATCCAAGGTGAGACGGGCACCGGGAAGGAGCTGGTGGCACGCGCCATCCATGAGCTGTCCGGCCGCA
CGAAGGGGCCCATGGAGGTGCTGGACTGCGGCGCCATTCCGCCCAACCTCATCGAAAGCGAGTTGTTCGGCCATGAGAAG
GGCGCCTTCACCGGCGCGGTGAGCAGCCGGCCAGGCGCCTTCGAGCGCGCGCACGGGGGCACCATCTTCCTGGACGAACT
GGGCGAGCTGCGGCTGGACCTTCAGCCCAAGCTGCTGCGCGTGCTGGAGAACCATGAAGTGCGGCGCGTGGGTGGCAACG
ACGTCATCGAGGTGGACTGCCGCGTCATCGCCGCCACCAACCGCGACCTGATGAAGGAGATTCAGGTCGGCGGCTTTCGC
GAGGACCTCTACTTCCGCTTGTCCGTCATCACCATCCAGCTGCCGCCGCTGCGACAGCGCCGCGACGACATCCCCCTCAT
CCTCAAGCGCGCGCTCGCGGACCCGGAAGTGGTGGGCAAGCACGGCAAGAAGCGTTTCTCCGCGGAGTCCCTGGGCCTGC
TGATGTCGTATTCATGGCCGGGCAACGTGCGTGAGCTGATGAACGTGTTGTCTCACGTCCTCACCTTCAGTGAGGGCGAG
GAGATTCAGCCCGCGCACCTGCCGCCTCGCGTGCGGGGACAGGTCCGCGAAGGGCCGCTGCCCTTCAACGAGCACCTCTC
CTTCAAAAACGCCAAGGAGCAACTGCTGGAGAACTTCGAGCGTGAATACATCACCAGCGTTTTGACGCGCTGCGAAGGAA
ACCTGTCTCGCGCCGCGCGTGAGAGTGGGCTCCACCGGAAGTCGATTGAACGGCTGGTGAAAAAGTACCAGTTGGACACA
AAGGGGATGAAGTCACGTTAG

Upstream 100 bases:

>100_bases
GGGACCCGGGCAGGACCGGGACCTTCTTCGGCTTCACTTTGCGCGGAGACATGGGCGGGGCACGAGAGCCTAGCACGGAC
GCCCGCGAGGGGCGGGCCTC

Downstream 100 bases:

>100_bases
CCCCATGAGTCAGCGGTGGATGCTGTAACTCGGTTGTTTCACGCCAGAAAAGCGCGTTTGTCGCAGAGCCGTGTTCTCCT
GTTCGCGATGCAAGGAACGC

Product: sigma-54 dependent trancsriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 486; Mature: 485

Protein sequence:

>486_residues
MGGLCYPRAQMSAPPLHPDDIHTSPGDVGQDLNHSPLLGETLVVDPRTTVKLHKCRLAVTSGPDTGRSVVSDKERLRCGA
HPGNDLVLVEDRTASRHHFEIQFTERGYLLVDLGSTNGTFLDGRRIERAYLSPGSQIRAGSSVLTFAPLDEEVTIEPDRE
GELCGMVGQSMKMRQIFGLIKKIAPMGVSVIIQGETGTGKELVARAIHELSGRTKGPMEVLDCGAIPPNLIESELFGHEK
GAFTGAVSSRPGAFERAHGGTIFLDELGELRLDLQPKLLRVLENHEVRRVGGNDVIEVDCRVIAATNRDLMKEIQVGGFR
EDLYFRLSVITIQLPPLRQRRDDIPLILKRALADPEVVGKHGKKRFSAESLGLLMSYSWPGNVRELMNVLSHVLTFSEGE
EIQPAHLPPRVRGQVREGPLPFNEHLSFKNAKEQLLENFEREYITSVLTRCEGNLSRAARESGLHRKSIERLVKKYQLDT
KGMKSR

Sequences:

>Translated_486_residues
MGGLCYPRAQMSAPPLHPDDIHTSPGDVGQDLNHSPLLGETLVVDPRTTVKLHKCRLAVTSGPDTGRSVVSDKERLRCGA
HPGNDLVLVEDRTASRHHFEIQFTERGYLLVDLGSTNGTFLDGRRIERAYLSPGSQIRAGSSVLTFAPLDEEVTIEPDRE
GELCGMVGQSMKMRQIFGLIKKIAPMGVSVIIQGETGTGKELVARAIHELSGRTKGPMEVLDCGAIPPNLIESELFGHEK
GAFTGAVSSRPGAFERAHGGTIFLDELGELRLDLQPKLLRVLENHEVRRVGGNDVIEVDCRVIAATNRDLMKEIQVGGFR
EDLYFRLSVITIQLPPLRQRRDDIPLILKRALADPEVVGKHGKKRFSAESLGLLMSYSWPGNVRELMNVLSHVLTFSEGE
EIQPAHLPPRVRGQVREGPLPFNEHLSFKNAKEQLLENFEREYITSVLTRCEGNLSRAARESGLHRKSIERLVKKYQLDT
KGMKSR
>Mature_485_residues
GGLCYPRAQMSAPPLHPDDIHTSPGDVGQDLNHSPLLGETLVVDPRTTVKLHKCRLAVTSGPDTGRSVVSDKERLRCGAH
PGNDLVLVEDRTASRHHFEIQFTERGYLLVDLGSTNGTFLDGRRIERAYLSPGSQIRAGSSVLTFAPLDEEVTIEPDREG
ELCGMVGQSMKMRQIFGLIKKIAPMGVSVIIQGETGTGKELVARAIHELSGRTKGPMEVLDCGAIPPNLIESELFGHEKG
AFTGAVSSRPGAFERAHGGTIFLDELGELRLDLQPKLLRVLENHEVRRVGGNDVIEVDCRVIAATNRDLMKEIQVGGFRE
DLYFRLSVITIQLPPLRQRRDDIPLILKRALADPEVVGKHGKKRFSAESLGLLMSYSWPGNVRELMNVLSHVLTFSEGEE
IQPAHLPPRVRGQVREGPLPFNEHLSFKNAKEQLLENFEREYITSVLTRCEGNLSRAARESGLHRKSIERLVKKYQLDTK
GMKSR

Specific function: Member of the two-component regulatory system zraS/zraR. When activated by zraS it acts in conjunction with sigma-54 to regulate the expression of zraP. Positively autoregulates the expression of the zraSR operon [H]

COG id: COG2204

COG function: function code T; Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1790437, Length=305, Percent_Identity=44.2622950819672, Blast_Score=260, Evalue=2e-70,
Organism=Escherichia coli, GI1788550, Length=331, Percent_Identity=43.5045317220544, Blast_Score=256, Evalue=3e-69,
Organism=Escherichia coli, GI1788905, Length=320, Percent_Identity=40.3125, Blast_Score=243, Evalue=2e-65,
Organism=Escherichia coli, GI87082117, Length=317, Percent_Identity=43.5331230283912, Blast_Score=238, Evalue=5e-64,
Organism=Escherichia coli, GI1790299, Length=338, Percent_Identity=39.6449704142012, Blast_Score=229, Evalue=4e-61,
Organism=Escherichia coli, GI1789087, Length=246, Percent_Identity=47.1544715447154, Blast_Score=226, Evalue=3e-60,
Organism=Escherichia coli, GI1789233, Length=336, Percent_Identity=40.7738095238095, Blast_Score=226, Evalue=3e-60,
Organism=Escherichia coli, GI87082152, Length=322, Percent_Identity=42.2360248447205, Blast_Score=223, Evalue=2e-59,
Organism=Escherichia coli, GI1786524, Length=325, Percent_Identity=40.9230769230769, Blast_Score=204, Evalue=9e-54,
Organism=Escherichia coli, GI87081872, Length=327, Percent_Identity=38.2262996941896, Blast_Score=194, Evalue=1e-50,
Organism=Escherichia coli, GI1787583, Length=321, Percent_Identity=36.4485981308411, Blast_Score=186, Evalue=4e-48,
Organism=Escherichia coli, GI1789828, Length=232, Percent_Identity=37.5, Blast_Score=130, Evalue=1e-31,
Organism=Escherichia coli, GI87081858, Length=331, Percent_Identity=28.0966767371601, Blast_Score=125, Evalue=9e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR011006
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02954 HTH_8; PF00072 Response_reg; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 53897; Mature: 53765

Theoretical pI: Translated: 7.67; Mature: 7.67

Prosite motif: PS50006 FHA_DOMAIN ; PS00675 SIGMA54_INTERACT_1 ; PS00676 SIGMA54_INTERACT_2 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGGLCYPRAQMSAPPLHPDDIHTSPGDVGQDLNHSPLLGETLVVDPRTTVKLHKCRLAVT
CCCCCCCCHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCEEEEEEEEEEE
SGPDTGRSVVSDKERLRCGAHPGNDLVLVEDRTASRHHFEIQFTERGYLLVDLGSTNGTF
CCCCCCHHHHCCHHHHEECCCCCCCEEEEECCCCCCEEEEEEEECCCEEEEEECCCCCCE
LDGRRIERAYLSPGSQIRAGSSVLTFAPLDEEVTIEPDREGELCGMVGQSMKMRQIFGLI
ECCCHHHHHHCCCCCCCCCCCCEEEEECCCCCEEECCCCCCCHHHHHHCCHHHHHHHHHH
KKIAPMGVSVIIQGETGTGKELVARAIHELSGRTKGPMEVLDCGAIPPNLIESELFGHEK
HHHHCCCEEEEEECCCCCCHHHHHHHHHHHCCCCCCCHHHHHCCCCCHHHHHHHHHCCCC
GAFTGAVSSRPGAFERAHGGTIFLDELGELRLDLQPKLLRVLENHEVRRVGGNDVIEVDC
CCEECCCCCCCCCCHHCCCCEEEEECCCCCEECCCHHHHHHHCCCCEEECCCCCEEEEEE
RVIAATNRDLMKEIQVGGFREDLYFRLSVITIQLPPLRQRRDDIPLILKRALADPEVVGK
EEEEECCHHHHHHHHCCCCCCCCEEEEEEEEEECCCCHHCCCCHHHHHHHHHCCHHHHHH
HGKKRFSAESLGLLMSYSWPGNVRELMNVLSHVLTFSEGEEIQPAHLPPRVRGQVREGPL
CCHHHCCHHHCCEEEEECCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCHHHCCCCCCCCC
PFNEHLSFKNAKEQLLENFEREYITSVLTRCEGNLSRAARESGLHRKSIERLVKKYQLDT
CHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCHHHHHHHHHHHHCCC
KGMKSR
CCCCCC
>Mature Secondary Structure 
GGLCYPRAQMSAPPLHPDDIHTSPGDVGQDLNHSPLLGETLVVDPRTTVKLHKCRLAVT
CCCCCCCHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCEEEEEEEEEEE
SGPDTGRSVVSDKERLRCGAHPGNDLVLVEDRTASRHHFEIQFTERGYLLVDLGSTNGTF
CCCCCCHHHHCCHHHHEECCCCCCCEEEEECCCCCCEEEEEEEECCCEEEEEECCCCCCE
LDGRRIERAYLSPGSQIRAGSSVLTFAPLDEEVTIEPDREGELCGMVGQSMKMRQIFGLI
ECCCHHHHHHCCCCCCCCCCCCEEEEECCCCCEEECCCCCCCHHHHHHCCHHHHHHHHHH
KKIAPMGVSVIIQGETGTGKELVARAIHELSGRTKGPMEVLDCGAIPPNLIESELFGHEK
HHHHCCCEEEEEECCCCCCHHHHHHHHHHHCCCCCCCHHHHHCCCCCHHHHHHHHHCCCC
GAFTGAVSSRPGAFERAHGGTIFLDELGELRLDLQPKLLRVLENHEVRRVGGNDVIEVDC
CCEECCCCCCCCCCHHCCCCEEEEECCCCCEECCCHHHHHHHCCCCEEECCCCCEEEEEE
RVIAATNRDLMKEIQVGGFREDLYFRLSVITIQLPPLRQRRDDIPLILKRALADPEVVGK
EEEEECCHHHHHHHHCCCCCCCCEEEEEEEEEECCCCHHCCCCHHHHHHHHHCCHHHHHH
HGKKRFSAESLGLLMSYSWPGNVRELMNVLSHVLTFSEGEEIQPAHLPPRVRGQVREGPL
CCHHHCCHHHCCEEEEECCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCHHHCCCCCCCCC
PFNEHLSFKNAKEQLLENFEREYITSVLTRCEGNLSRAARESGLHRKSIERLVKKYQLDT
CHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCHHHHHHHHHHHHCCC
KGMKSR
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11243806 [H]