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The map label for this gene is cheA4 [H]

Identifier: 108761624

GI number: 108761624

Start: 3133153

End: 3135699

Strand: Direct

Name: cheA4 [H]

Synonym: MXAN_2686

Alternate gene names: 108761624

Gene position: 3133153-3135699 (Clockwise)

Preceding gene: 108760558

Following gene: 108762209

Centisome position: 34.28

GC content: 73.26

Gene sequence:

>2547_bases
ATGGATCCTCAGCTCTTGCGCAGCATCTGGCCGGTGTTCTCCGCGGAGACGCGCGAGCAGATTCAAGCCATCGGGTCGAA
GGTGTTGGGGCTGGAGGGCCCGGCGCAGGGGCGTGAGCCGGACCTGCTCCCGTCGCTCAAGCGGCTGGTCCACAGCCTCA
AGGGCTCCGCGGCCAGCCTGGGCCTGGACGACATCGAGCAGGTGGTGCACGCCATCGAGGACGGGCTGGCCACCTTCAAT
CAGGAGGAGCGGCTGCCCCGCGACACGGTGGAGGCCATGCTGCGCGGCCTCTCCGCCATCGAAGGCGCCATGGCCCGTGG
CGACGCCGGACAGTCGCCCGTGGTGGAAGGACTGTCCTCGCTGCTGGCGGCCCTGGGCCACGAGTCCGCGGAGGCCGTCC
CCCAGACGGCGGCCTCGGGCGCGGCCGCGCAGGCGTTGGAGGTGCTGGACCTCCTCGAAGCGGGGTTGAGCGCGCTGTGC
TCGCCGGATGTGCCGGACCGGGCGGCCGTGGTGCGCACGGCGGTGGAGCGGGCCCGCACGTTGAAGGCGTCCGCCGAGTC
CGCCGGGGCGCAGAAGGTGGCCACGCTGGCGGAAGCCGCGGCGCTGGGCTTCACGCGCATGGAGCCGGGCGGTGACTCCG
CGGGGCTGGCCGCATCGGACGTGGCTGGCACGCTGGTGGACCTGCGGACGGCGTTGGAGGCCGAGGGTGGCGCAGGGGCG
GTGGCCCGCGCCGTCCATTCGCTGCGCGCGTCGCCGTCTCCCGCGCCCGTGGAAGGCGCGGCGGCACAGGGGCCCGCGGG
AGCTGCGGCCACGACGGAGTCCCGCGGACCGGCGGACCAGACGGTGCGCGTGTCGGTGAAGACGCTGGAGTCCATCGCGC
TCCAGGTGGAGCTGCTCCTGGCCGGACGCGCGCAGCAGACGCGGCGTGGCGCGGCGCACCGCGTGTTGATGGACGGCATG
CGCGAGGTGCTCATGCACCTGGAGCGCGCGTCGTCGCAGCTCGCGATGGCGGGCGGCGGTCCTGCGCTGGAGCCACTCCG
CGCGGGCGTGACGCAGATGCGCGGACTGCAGAAGCAGCTCCTGGAGCTGACGAAGGAGTCGCACCGCGACGGTGAGCAGC
TCACGCTGGTGGCCCAGGTGGCGCGCGATGATTTGCGCGACCTGCGCATGGTGCCGGCCTCGCAGGTGCTGGAGCCCCTG
CGGCGCACCGTGCGCGAGACGTCCGCGCGGCTGAACAAGCAGGTGACGCTGGAGCTGTCGGGCGGCGAGGTCCGGTTGGA
CCGGCGCATCCTCGACGCGCTGAAGGACCCGCTGCTGCACCTGGTGCGCAACGCCATCGACCACGGCCTGGAGTCCACCG
AGGAGCGGCGGGTCGCGGGCAAGTCCGAAGCGGGGCGGCTGACGGTGCGGGTGGAGCCTCGGGGCTCGCGCATCGCGGTG
GTGGTGGAGGATGACGGCTCCGGCTTGTCACCCAGCCGGGTGCGCGCCACGGCGGTGCGGCGGGGGCTGCTGCCGGCCGA
TGAGGCGGAGAAGCTGTCGGACGCGCAGGCGGCGCGGCTCATCTTCCAGCCAGGCTTCTCCACACGGGAGCAGGTGTCCG
CGACGTCCGGGCGGGGCGTGGGTCTGGATGTGGTGCAGGCGACGGCGCAACGGCTCCAGGGCTCGGTGGACGTGGCCTTC
ACGGCGGGCCGGGGCACGCGCTTCACCGTGGACCTGCCGCTGACGCTGGCCGCGGCGTTGGGGTTGCTCGTGCGCACGGG
CACCACGGTGTCCGCCATTCCCTCCGACAGCGTGAATCGCATCCTCCGGTTGAACCCGGACGACGTGGGCACCGTCGCGG
GCCGCGTGGTGGCGCGGCTGGATGGGGAGCAGCTCACGTTCCTGCCGCTGGCGGAGGCCATTGGCCTGCCCCGGCTGCCG
CTGGCGCTGGACTCCGGGAACGTGCAGGCCGCCGCGCTGCTGACGGTGGGCGAGGACAAAGTACTGTTCGCCATCGACGA
GGTGGTGGGGCAGCAGGAGATTGTCGTCCGCTCGCTGGGGCGCCACCTCAAGGGCGTGCGGCACCTGGCGGGCGCGGCGG
TGCTGGACGACGGCCGCGTGGTGCCGGTGCTCAACGCCGCGGAGTTGGTGCGCGCGGCGCGGCCGGAGACGCGCTCGGTG
GCTCGCGAGACGGCGCGGCCTCGCATCCTCGTGTGTGACGACGCGCTCACCACGCGCTTCGCCATGAAGTCGCTGCTGGA
GATTGCCGGCTACCCGGTGGTGACCGCGGCGGACGGTGAAGAGGCGTGGGGCATCCTGGAGCGCACGCCCTGCCAACTGG
TGGTCAGCGACTGGCAGATGCCCCGGCTGGACGGCGTGGGGCTGGCGCGGCGAATCAAGTCGCACCCGCAGCTGCACCGC
ACGCCCATCATCCTGGTGACGTCGCTCGACAGTCCCGAGGACCGCGCCGCTGGTCTGGAGGCGGGCGCGGACGGGTACCT
CGTCAAGCGCGAGGTGGAGCGAGGCCGCCTGCTGGAGCTGGTGCGCCAACTGCTGCCCGTGTCCTGA

Upstream 100 bases:

>100_bases
GCCCTTCTTGTTCCTCACGCCGGACCGGCTGACGGTGTTGGACCTGGAGCAGCTCGGGGGCCCGTCCGCCACGCGGCCCG
AAGGGGAGTAGGCACGCGCC

Downstream 100 bases:

>100_bases
CGGCGCCGCGCCTCACGCGTCGCGAGGCGCCACGGGCACGGTGTCATCCACCGGCAGGTGGACCACCCAGCCGTTGCCGG
TCTCCTCCGGCAACGAGAGG

Product: sensor histidine kinase/response regulator CheA4

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 848; Mature: 848

Protein sequence:

>848_residues
MDPQLLRSIWPVFSAETREQIQAIGSKVLGLEGPAQGREPDLLPSLKRLVHSLKGSAASLGLDDIEQVVHAIEDGLATFN
QEERLPRDTVEAMLRGLSAIEGAMARGDAGQSPVVEGLSSLLAALGHESAEAVPQTAASGAAAQALEVLDLLEAGLSALC
SPDVPDRAAVVRTAVERARTLKASAESAGAQKVATLAEAAALGFTRMEPGGDSAGLAASDVAGTLVDLRTALEAEGGAGA
VARAVHSLRASPSPAPVEGAAAQGPAGAAATTESRGPADQTVRVSVKTLESIALQVELLLAGRAQQTRRGAAHRVLMDGM
REVLMHLERASSQLAMAGGGPALEPLRAGVTQMRGLQKQLLELTKESHRDGEQLTLVAQVARDDLRDLRMVPASQVLEPL
RRTVRETSARLNKQVTLELSGGEVRLDRRILDALKDPLLHLVRNAIDHGLESTEERRVAGKSEAGRLTVRVEPRGSRIAV
VVEDDGSGLSPSRVRATAVRRGLLPADEAEKLSDAQAARLIFQPGFSTREQVSATSGRGVGLDVVQATAQRLQGSVDVAF
TAGRGTRFTVDLPLTLAAALGLLVRTGTTVSAIPSDSVNRILRLNPDDVGTVAGRVVARLDGEQLTFLPLAEAIGLPRLP
LALDSGNVQAAALLTVGEDKVLFAIDEVVGQQEIVVRSLGRHLKGVRHLAGAAVLDDGRVVPVLNAAELVRAARPETRSV
ARETARPRILVCDDALTTRFAMKSLLEIAGYPVVTAADGEEAWGILERTPCQLVVSDWQMPRLDGVGLARRIKSHPQLHR
TPIILVTSLDSPEDRAAGLEAGADGYLVKREVERGRLLELVRQLLPVS

Sequences:

>Translated_848_residues
MDPQLLRSIWPVFSAETREQIQAIGSKVLGLEGPAQGREPDLLPSLKRLVHSLKGSAASLGLDDIEQVVHAIEDGLATFN
QEERLPRDTVEAMLRGLSAIEGAMARGDAGQSPVVEGLSSLLAALGHESAEAVPQTAASGAAAQALEVLDLLEAGLSALC
SPDVPDRAAVVRTAVERARTLKASAESAGAQKVATLAEAAALGFTRMEPGGDSAGLAASDVAGTLVDLRTALEAEGGAGA
VARAVHSLRASPSPAPVEGAAAQGPAGAAATTESRGPADQTVRVSVKTLESIALQVELLLAGRAQQTRRGAAHRVLMDGM
REVLMHLERASSQLAMAGGGPALEPLRAGVTQMRGLQKQLLELTKESHRDGEQLTLVAQVARDDLRDLRMVPASQVLEPL
RRTVRETSARLNKQVTLELSGGEVRLDRRILDALKDPLLHLVRNAIDHGLESTEERRVAGKSEAGRLTVRVEPRGSRIAV
VVEDDGSGLSPSRVRATAVRRGLLPADEAEKLSDAQAARLIFQPGFSTREQVSATSGRGVGLDVVQATAQRLQGSVDVAF
TAGRGTRFTVDLPLTLAAALGLLVRTGTTVSAIPSDSVNRILRLNPDDVGTVAGRVVARLDGEQLTFLPLAEAIGLPRLP
LALDSGNVQAAALLTVGEDKVLFAIDEVVGQQEIVVRSLGRHLKGVRHLAGAAVLDDGRVVPVLNAAELVRAARPETRSV
ARETARPRILVCDDALTTRFAMKSLLEIAGYPVVTAADGEEAWGILERTPCQLVVSDWQMPRLDGVGLARRIKSHPQLHR
TPIILVTSLDSPEDRAAGLEAGADGYLVKREVERGRLLELVRQLLPVS
>Mature_848_residues
MDPQLLRSIWPVFSAETREQIQAIGSKVLGLEGPAQGREPDLLPSLKRLVHSLKGSAASLGLDDIEQVVHAIEDGLATFN
QEERLPRDTVEAMLRGLSAIEGAMARGDAGQSPVVEGLSSLLAALGHESAEAVPQTAASGAAAQALEVLDLLEAGLSALC
SPDVPDRAAVVRTAVERARTLKASAESAGAQKVATLAEAAALGFTRMEPGGDSAGLAASDVAGTLVDLRTALEAEGGAGA
VARAVHSLRASPSPAPVEGAAAQGPAGAAATTESRGPADQTVRVSVKTLESIALQVELLLAGRAQQTRRGAAHRVLMDGM
REVLMHLERASSQLAMAGGGPALEPLRAGVTQMRGLQKQLLELTKESHRDGEQLTLVAQVARDDLRDLRMVPASQVLEPL
RRTVRETSARLNKQVTLELSGGEVRLDRRILDALKDPLLHLVRNAIDHGLESTEERRVAGKSEAGRLTVRVEPRGSRIAV
VVEDDGSGLSPSRVRATAVRRGLLPADEAEKLSDAQAARLIFQPGFSTREQVSATSGRGVGLDVVQATAQRLQGSVDVAF
TAGRGTRFTVDLPLTLAAALGLLVRTGTTVSAIPSDSVNRILRLNPDDVGTVAGRVVARLDGEQLTFLPLAEAIGLPRLP
LALDSGNVQAAALLTVGEDKVLFAIDEVVGQQEIVVRSLGRHLKGVRHLAGAAVLDDGRVVPVLNAAELVRAARPETRSV
ARETARPRILVCDDALTTRFAMKSLLEIAGYPVVTAADGEEAWGILERTPCQLVVSDWQMPRLDGVGLARRIKSHPQLHR
TPIILVTSLDSPEDRAAGLEAGADGYLVKREVERGRLLELVRQLLPVS

Specific function: FrzE is involved in a sensory transduction pathway that controls the frequency at which cells reverse their gliding direction. FrzE seems to be capable of autophosphorylating itself on an histidine residue and then to transfer that group to an aspartate r

COG id: COG0643

COG function: function code NT; Chemotaxis protein histidine kinase and related kinases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788197, Length=355, Percent_Identity=35.4929577464789, Blast_Score=195, Evalue=8e-51,
Organism=Escherichia coli, GI1790863, Length=103, Percent_Identity=36.8932038834951, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1789809, Length=102, Percent_Identity=37.2549019607843, Blast_Score=64, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR002545
- InterPro:   IPR011006
- InterPro:   IPR004358
- InterPro:   IPR008207
- InterPro:   IPR005467
- InterPro:   IPR001789 [H]

Pfam domain/function: PF01584 CheW; PF02518 HATPase_c; PF01627 Hpt; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 89442; Mature: 89442

Theoretical pI: Translated: 6.12; Mature: 6.12

Prosite motif: PS50851 CHEW ; PS50894 HPT ; PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDPQLLRSIWPVFSAETREQIQAIGSKVLGLEGPAQGREPDLLPSLKRLVHSLKGSAASL
CCHHHHHHHHHHHCHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHC
GLDDIEQVVHAIEDGLATFNQEERLPRDTVEAMLRGLSAIEGAMARGDAGQSPVVEGLSS
CHHHHHHHHHHHHHHHHHCCHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHH
LLAALGHESAEAVPQTAASGAAAQALEVLDLLEAGLSALCSPDVPDRAAVVRTAVERART
HHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
LKASAESAGAQKVATLAEAAALGFTRMEPGGDSAGLAASDVAGTLVDLRTALEAEGGAGA
HHHHHHHCCHHHHHHHHHHHHHCCEECCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCHH
VARAVHSLRASPSPAPVEGAAAQGPAGAAATTESRGPADQTVRVSVKTLESIALQVELLL
HHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHH
AGRAQQTRRGAAHRVLMDGMREVLMHLERASSQLAMAGGGPALEPLRAGVTQMRGLQKQL
HCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCHHHHHHHHHHHHHHHHHH
LELTKESHRDGEQLTLVAQVARDDLRDLRMVPASQVLEPLRRTVRETSARLNKQVTLELS
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCEEEEEEC
GGEVRLDRRILDALKDPLLHLVRNAIDHGLESTEERRVAGKSEAGRLTVRVEPRGSRIAV
CCEEEHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCEEEEEECCCCCEEEE
VVEDDGSGLSPSRVRATAVRRGLLPADEAEKLSDAQAARLIFQPGFSTREQVSATSGRGV
EEECCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCCCC
GLDVVQATAQRLQGSVDVAFTAGRGTRFTVDLPLTLAAALGLLVRTGTTVSAIPSDSVNR
CHHHHHHHHHHHCCCCEEEEECCCCCEEEEECCHHHHHHHHHHHHCCCCEEECCCHHHCC
ILRLNPDDVGTVAGRVVARLDGEQLTFLPLAEAIGLPRLPLALDSGNVQAAALLTVGEDK
EEECCCCHHHHHHHHHHHHCCCCCEEEEEHHHHCCCCCCCEEECCCCCEEEEEEEECCCC
VLFAIDEVVGQQEIVVRSLGRHLKGVRHLAGAAVLDDGRVVPVLNAAELVRAARPETRSV
EEEEHHHHHCHHHHHHHHHHHHHHHHHHHHCCCEECCCCEEEECCHHHHHHHCCCHHHHH
ARETARPRILVCDDALTTRFAMKSLLEIAGYPVVTAADGEEAWGILERTPCQLVVSDWQM
HHHHCCCEEEEECCHHHHHHHHHHHHHHCCCCEEEECCCHHHCCHHHCCCHHEEECCCCC
PRLDGVGLARRIKSHPQLHRTPIILVTSLDSPEDRAAGLEAGADGYLVKREVERGRLLEL
CCCCCCHHHHHHHCCCCCCCCCEEEEECCCCCCHHHCCCCCCCCCCEEHHHHHHHHHHHH
VRQLLPVS
HHHHCCCC
>Mature Secondary Structure
MDPQLLRSIWPVFSAETREQIQAIGSKVLGLEGPAQGREPDLLPSLKRLVHSLKGSAASL
CCHHHHHHHHHHHCHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHC
GLDDIEQVVHAIEDGLATFNQEERLPRDTVEAMLRGLSAIEGAMARGDAGQSPVVEGLSS
CHHHHHHHHHHHHHHHHHCCHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHH
LLAALGHESAEAVPQTAASGAAAQALEVLDLLEAGLSALCSPDVPDRAAVVRTAVERART
HHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
LKASAESAGAQKVATLAEAAALGFTRMEPGGDSAGLAASDVAGTLVDLRTALEAEGGAGA
HHHHHHHCCHHHHHHHHHHHHHCCEECCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCHH
VARAVHSLRASPSPAPVEGAAAQGPAGAAATTESRGPADQTVRVSVKTLESIALQVELLL
HHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHH
AGRAQQTRRGAAHRVLMDGMREVLMHLERASSQLAMAGGGPALEPLRAGVTQMRGLQKQL
HCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCHHHHHHHHHHHHHHHHHH
LELTKESHRDGEQLTLVAQVARDDLRDLRMVPASQVLEPLRRTVRETSARLNKQVTLELS
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCEEEEEEC
GGEVRLDRRILDALKDPLLHLVRNAIDHGLESTEERRVAGKSEAGRLTVRVEPRGSRIAV
CCEEEHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCEEEEEECCCCCEEEE
VVEDDGSGLSPSRVRATAVRRGLLPADEAEKLSDAQAARLIFQPGFSTREQVSATSGRGV
EEECCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCCCC
GLDVVQATAQRLQGSVDVAFTAGRGTRFTVDLPLTLAAALGLLVRTGTTVSAIPSDSVNR
CHHHHHHHHHHHCCCCEEEEECCCCCEEEEECCHHHHHHHHHHHHCCCCEEECCCHHHCC
ILRLNPDDVGTVAGRVVARLDGEQLTFLPLAEAIGLPRLPLALDSGNVQAAALLTVGEDK
EEECCCCHHHHHHHHHHHHCCCCCEEEEEHHHHCCCCCCCEEECCCCCEEEEEEEECCCC
VLFAIDEVVGQQEIVVRSLGRHLKGVRHLAGAAVLDDGRVVPVLNAAELVRAARPETRSV
EEEEHHHHHCHHHHHHHHHHHHHHHHHHHHCCCEECCCCEEEECCHHHHHHHCCCHHHHH
ARETARPRILVCDDALTTRFAMKSLLEIAGYPVVTAADGEEAWGILERTPCQLVVSDWQM
HHHHCCCEEEEECCHHHHHHHHHHHHHHCCCCEEEECCCHHHCCHHHCCCHHEEECCCCC
PRLDGVGLARRIKSHPQLHRTPIILVTSLDSPEDRAAGLEAGADGYLVKREVERGRLLEL
CCCCCCHHHHHHHCCCCCCCCCEEEEECCCCCCHHHCCCCCCCCCCEEHHHHHHHHHHHH
VRQLLPVS
HHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2165608; 2123853 [H]