Click here to switch to the map view.

The map label for this gene is asd [H]

Identifier: 108761611

GI number: 108761611

Start: 3578878

End: 3579966

Strand: Direct

Name: asd [H]

Synonym: MXAN_3050

Alternate gene names: 108761611

Gene position: 3578878-3579966 (Clockwise)

Preceding gene: 108758330

Following gene: 108762705

Centisome position: 39.16

GC content: 67.49

Gene sequence:

>1089_bases
ATGGCCAGGCTTCGTGCGGCCCTCATCGGTGCCACTGGACTCGCCGGACAGCAATTCATCGCCGCCCTGAAGAATCACCC
CTCCATCGAACTGACGGGGCTCGCGGCCTCGCCTCGCTCGGCGGGCAAGACGTATGCGGAGGCGCTGAAAACGGCGAGTG
GCATGACGGCCTGGTTCGTCCCGGAGCCGCTGCCCGCCGAGCTCGCCGGCATGAAGGTGGTGGCCGGTGACGCGCTCGAG
GCCAAGGATTACGACCTGGTCTTCTCCGCCGTGGAGGCGGACGTGGCACGCGAGCTGGAGCCTCGGCTGGCGAAGGACAT
CCCCGTCTTTTCCGCCGCCAGCGCGTTCCGATACGAAGACGACGTCCCGTTGCTGATTCCCCCCGTCAACGCCGCGCACG
CGCCCCTCATCCGGGAGCAGCAGCGCCGGCGTGGCTGGAAGGGCTTCATCGTCCCCATCCCCAACTGCACGACCACCGGC
CTGGCGGTGACGCTGGCGCCGCTGGTGGAGCGCTTCGGGGTGAAGGCGGTGCTGATGACCAGCCTCCAGGCCATGTCCGG
CGCCGGCCGCTCGCCGGGCGTCATCGGCATGGACATCCTCGACAACGTCATCCCCTATATTCCCAAGGAGGAGCACAAGG
TCGAGGTGGAGACGAAGAAGATTCTCGGCGCGCTGCGTCCAGCGGGTGACGGCCTCACGCCGCATGACGTTCGGGTGTCC
TGCACCTGCACCCGCGTGGCGGTGATGGAGGGCCACACCGAGTCCGTCTTCGTCTCATTGGACAAGAAGGCGACTGTGGC
CGAAGTGACCCAGGCCCTGCGGGAGTGGAAGGGTGCCGAGCTGGCTCGGAACCTGCCGTCCGCCGCACCGCGCTGGATTG
AAGTGCTGGACGATCCTTTCCGACCCCAGCCCCGTTTGGACCGGGACACGCATGGCGGTATGGCCACCACCGTCGGACGC
ATCCGCGAGGATGGCGTCCTGGAGAACGGCTTCAAGTACGTGCTGGTGTCGCACAACACCAAGATGGGAGCCGCGCGAGG
CGCCATCCTCGTGGCCGAGCTGCTGTTGGCCCAGGGCTTGGTGGGCTGA

Upstream 100 bases:

>100_bases
CGCCGCGATTCCCCGCTGAGCACCAGGGTGGGTGCGGTGCGTCGTCAAACGGTGTTATGGAGCGGCGACATCCTCCTCTG
GAGACTGGAGAAACGCCCCC

Downstream 100 bases:

>100_bases
GCCCCGCTACCGGCGAAGGGGTGGCACAGATTCAGAGTGCCATCGTCAGCTCGAACCACTACTCTGCGCGCCCACGGACG
CGCCTGGTTTCAACCGAGAG

Product: aspartate-semialdehyde dehydrogenase

Products: NA

Alternate protein names: ASA dehydrogenase; ASADH [H]

Number of amino acids: Translated: 362; Mature: 361

Protein sequence:

>362_residues
MARLRAALIGATGLAGQQFIAALKNHPSIELTGLAASPRSAGKTYAEALKTASGMTAWFVPEPLPAELAGMKVVAGDALE
AKDYDLVFSAVEADVARELEPRLAKDIPVFSAASAFRYEDDVPLLIPPVNAAHAPLIREQQRRRGWKGFIVPIPNCTTTG
LAVTLAPLVERFGVKAVLMTSLQAMSGAGRSPGVIGMDILDNVIPYIPKEEHKVEVETKKILGALRPAGDGLTPHDVRVS
CTCTRVAVMEGHTESVFVSLDKKATVAEVTQALREWKGAELARNLPSAAPRWIEVLDDPFRPQPRLDRDTHGGMATTVGR
IREDGVLENGFKYVLVSHNTKMGAARGAILVAELLLAQGLVG

Sequences:

>Translated_362_residues
MARLRAALIGATGLAGQQFIAALKNHPSIELTGLAASPRSAGKTYAEALKTASGMTAWFVPEPLPAELAGMKVVAGDALE
AKDYDLVFSAVEADVARELEPRLAKDIPVFSAASAFRYEDDVPLLIPPVNAAHAPLIREQQRRRGWKGFIVPIPNCTTTG
LAVTLAPLVERFGVKAVLMTSLQAMSGAGRSPGVIGMDILDNVIPYIPKEEHKVEVETKKILGALRPAGDGLTPHDVRVS
CTCTRVAVMEGHTESVFVSLDKKATVAEVTQALREWKGAELARNLPSAAPRWIEVLDDPFRPQPRLDRDTHGGMATTVGR
IREDGVLENGFKYVLVSHNTKMGAARGAILVAELLLAQGLVG
>Mature_361_residues
ARLRAALIGATGLAGQQFIAALKNHPSIELTGLAASPRSAGKTYAEALKTASGMTAWFVPEPLPAELAGMKVVAGDALEA
KDYDLVFSAVEADVARELEPRLAKDIPVFSAASAFRYEDDVPLLIPPVNAAHAPLIREQQRRRGWKGFIVPIPNCTTTGL
AVTLAPLVERFGVKAVLMTSLQAMSGAGRSPGVIGMDILDNVIPYIPKEEHKVEVETKKILGALRPAGDGLTPHDVRVSC
TCTRVAVMEGHTESVFVSLDKKATVAEVTQALREWKGAELARNLPSAAPRWIEVLDDPFRPQPRLDRDTHGGMATTVGRI
REDGVLENGFKYVLVSHNTKMGAARGAILVAELLLAQGLVG

Specific function: This enzyme catalyzes the second step in the common metabolic pathway to synthesize Thr and Met from Asp [H]

COG id: COG0136

COG function: function code E; Aspartate-semialdehyde dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aspartate-semialdehyde dehydrogenase family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6320362, Length=368, Percent_Identity=42.9347826086957, Blast_Score=268, Evalue=1e-72,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000319
- InterPro:   IPR005676
- InterPro:   IPR012080
- InterPro:   IPR016040
- InterPro:   IPR000534
- InterPro:   IPR012280 [H]

Pfam domain/function: PF01118 Semialdhyde_dh; PF02774 Semialdhyde_dhC [H]

EC number: =1.2.1.11 [H]

Molecular weight: Translated: 38715; Mature: 38584

Theoretical pI: Translated: 7.63; Mature: 7.63

Prosite motif: PS01103 ASD

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARLRAALIGATGLAGQQFIAALKNHPSIELTGLAASPRSAGKTYAEALKTASGMTAWFV
CCCHHHHHHCCCCCCHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHCCCEEEEC
PEPLPAELAGMKVVAGDALEAKDYDLVFSAVEADVARELEPRLAKDIPVFSAASAFRYED
CCCCCHHHCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCC
DVPLLIPPVNAAHAPLIREQQRRRGWKGFIVPIPNCTTTGLAVTLAPLVERFGVKAVLMT
CCCEEECCCCCCCCHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHHHCCHHHHHH
SLQAMSGAGRSPGVIGMDILDNVIPYIPKEEHKVEVETKKILGALRPAGDGLTPHDVRVS
HHHHHHCCCCCCCEEEHHHHHHHHCCCCCCCCEEEHHHHHHHHHHCCCCCCCCCCCEEEE
CTCTRVAVMEGHTESVFVSLDKKATVAEVTQALREWKGAELARNLPSAAPRWIEVLDDPF
EEEEEEEEECCCCCEEEEEECCCCHHHHHHHHHHHCCCHHHHHCCCCCCHHHHHHHCCCC
RPQPRLDRDTHGGMATTVGRIREDGVLENGFKYVLVSHNTKMGAARGAILVAELLLAQGL
CCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHCC
VG
CC
>Mature Secondary Structure 
ARLRAALIGATGLAGQQFIAALKNHPSIELTGLAASPRSAGKTYAEALKTASGMTAWFV
CCHHHHHHCCCCCCHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHCCCEEEEC
PEPLPAELAGMKVVAGDALEAKDYDLVFSAVEADVARELEPRLAKDIPVFSAASAFRYED
CCCCCHHHCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCC
DVPLLIPPVNAAHAPLIREQQRRRGWKGFIVPIPNCTTTGLAVTLAPLVERFGVKAVLMT
CCCEEECCCCCCCCHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHHHCCHHHHHH
SLQAMSGAGRSPGVIGMDILDNVIPYIPKEEHKVEVETKKILGALRPAGDGLTPHDVRVS
HHHHHHCCCCCCCEEEHHHHHHHHCCCCCCCCEEEHHHHHHHHHHCCCCCCCCCCCEEEE
CTCTRVAVMEGHTESVFVSLDKKATVAEVTQALREWKGAELARNLPSAAPRWIEVLDDPF
EEEEEEEEECCCCCEEEEEECCCCHHHHHHHHHHHCCCHHHHHCCCCCCHHHHHHHCCCC
RPQPRLDRDTHGGMATTVGRIREDGVLENGFKYVLVSHNTKMGAARGAILVAELLLAQGL
CCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHCC
VG
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9371463 [H]