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The map label for this gene is yycG [H]

Identifier: 108761495

GI number: 108761495

Start: 3844556

End: 3846148

Strand: Reverse

Name: yycG [H]

Synonym: MXAN_3290

Alternate gene names: 108761495

Gene position: 3846148-3844556 (Counterclockwise)

Preceding gene: 108760676

Following gene: 108762554

Centisome position: 42.08

GC content: 69.18

Gene sequence:

>1593_bases
GTGGAAGCGGATGTTGCTCACCGCGCCCTGCTGGAGATGTCGCGGCACCTGACGGACAACGCGGGGCCCACCGAAGCGCT
CCGCGCCCACCTGCAGACCATCCACACACTCCTCAAGCCGAAGGTCTGCTACGTGGCGCGCTACTTCCCATCCCGGGAGC
AGCTCCACGTCGAGCACGTGCGAGGCCGTTACGACGACCGCGTCACCGCCGCCGTCCCCGGTGAGGGCGTGGTGGGCCGG
GCCTTCTCCCAGAAGGCGCTGCTGCGTGATGGGGACACAGTCGCCGTGCCACTCGAGGGCCCGCAAGGCGTCGGTGGCGT
CCTGGTGGTGCTGGGCTCCCGGCGCGAGCCGTCCGACACGCTGTTGCAGTCACTGGCGGCGCAGCTCACCGCCGCCTACG
AGGTGGCGCGCCTGCGTGACGACAGCGCCCGCCGCAACAAGGACCTGCAGACGGCCATCGCTGGCCTCAAGAGCCTGGAG
CAGAACCGCGAGGAGCTGCTGGGCAACGTCTCGCACGACCTGAAGAACCCGCTCACCACCATCAAGTCCTACCTGGCGAT
GATGGGCCGCGAGAAGCTGGGGCCCCTCACGGATGCCCAGCGCCGCGCGGTGCAGATCTGCGACCGGAACTCGGACCGGA
TGCTGCGCATGGTGAACGATTTGCTGCTCATGTCCCGGCTCCAGTCCGGGAAGATGCAGCTCAATCAGCGTCCCTTCGGC
CTCAAGGCCGTGGCGGAGGAAGTGGTGCGCTCACTGGGGGCGCTCGCGGAGCACTGCAAGGTACGCGTGGTGATTCCCCC
CTGCCCCGAGGTGTTCGTCCGCGGCGACCGCGAGCGCATCGCCGAGGCCATCCACAACCTCGTGGAGAACGGCATCCACC
ACAGCGAGGCGGACGACACCGTCGAGGTGCGCGTCTCCGCCGAGGACGGCCTGGCGATGCTGACCGTGAAGGACAGCGGC
CCGGGCATGTCCAGCGAGGCCCTGGAGCACGTCTTCGACGCCTTCTACCGCGCCACCCCGGGCATGCCCCGGCCGCCTGG
TGCGGGGCTCGGGTTGCCGCTGGTAGGGAAGATTGTCGCCCTCCATGGCGGACGAATGGAGAGCGCCAGCGTCCTGGGCG
AGGGCAGCACGTTCCAGATGGTGCTCCCCATGTTCGCCGGCGCCGTCAGCGCGCCGGAGATGGCCCAGGCGGCGCCCAAG
AGCGGCGGCATCCTGCTGGTGGAGGACGACGCCGACTGCCGGGAGGTGCTGCAGCAGGTGCTGGAGCAGGAGGGCTACCG
GGTGATGGCCACCTCGGGCGCATCCGAGGCACGGTCCATTCTCTCTCACATCCGGCCAGCCATGGTCCTGCTCGACCTGC
GGCTGAGCGAGGAGGATGGGCAATCGGTGCTCCGCTACATCCGTGGCAACGAGTCGCTGGCGGACATCGTCGTGTACATC
ATCTCCGGAGCCACCGAGGTGGCGTCACTCACCTCGGGCCAGGGGCTGGAGCGCATCGACGGCTTCTTCGAAAAGCCCCT
CAACCTGCCCAAGCTGCTGGACACCGTCTCTGCGGTGGTCCGGCCCAGCCGGCGAGCCCCCGCCGTGCCGTGA

Upstream 100 bases:

>100_bases
CTCAAAGAAGAAGGGGACGCTGGCGGAAGTCGTACCGCTGCGTCCGGTTGCGAAGGCGGCCAAGAAGACTCCGAAGCGGC
CCGCGAAGCCGCTCCCCTCG

Downstream 100 bases:

>100_bases
CTGGGGGATTCGCCGCGGGCGCGAACAAGAGGTGGCCGGAAGCCACCTCGGTTTGTCTAGTATCCCCGCAGCCCCATGAG
CACATCCGTCTACTCCCGTT

Product: sensor histidine kinase/response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 530; Mature: 530

Protein sequence:

>530_residues
MEADVAHRALLEMSRHLTDNAGPTEALRAHLQTIHTLLKPKVCYVARYFPSREQLHVEHVRGRYDDRVTAAVPGEGVVGR
AFSQKALLRDGDTVAVPLEGPQGVGGVLVVLGSRREPSDTLLQSLAAQLTAAYEVARLRDDSARRNKDLQTAIAGLKSLE
QNREELLGNVSHDLKNPLTTIKSYLAMMGREKLGPLTDAQRRAVQICDRNSDRMLRMVNDLLLMSRLQSGKMQLNQRPFG
LKAVAEEVVRSLGALAEHCKVRVVIPPCPEVFVRGDRERIAEAIHNLVENGIHHSEADDTVEVRVSAEDGLAMLTVKDSG
PGMSSEALEHVFDAFYRATPGMPRPPGAGLGLPLVGKIVALHGGRMESASVLGEGSTFQMVLPMFAGAVSAPEMAQAAPK
SGGILLVEDDADCREVLQQVLEQEGYRVMATSGASEARSILSHIRPAMVLLDLRLSEEDGQSVLRYIRGNESLADIVVYI
ISGATEVASLTSGQGLERIDGFFEKPLNLPKLLDTVSAVVRPSRRAPAVP

Sequences:

>Translated_530_residues
MEADVAHRALLEMSRHLTDNAGPTEALRAHLQTIHTLLKPKVCYVARYFPSREQLHVEHVRGRYDDRVTAAVPGEGVVGR
AFSQKALLRDGDTVAVPLEGPQGVGGVLVVLGSRREPSDTLLQSLAAQLTAAYEVARLRDDSARRNKDLQTAIAGLKSLE
QNREELLGNVSHDLKNPLTTIKSYLAMMGREKLGPLTDAQRRAVQICDRNSDRMLRMVNDLLLMSRLQSGKMQLNQRPFG
LKAVAEEVVRSLGALAEHCKVRVVIPPCPEVFVRGDRERIAEAIHNLVENGIHHSEADDTVEVRVSAEDGLAMLTVKDSG
PGMSSEALEHVFDAFYRATPGMPRPPGAGLGLPLVGKIVALHGGRMESASVLGEGSTFQMVLPMFAGAVSAPEMAQAAPK
SGGILLVEDDADCREVLQQVLEQEGYRVMATSGASEARSILSHIRPAMVLLDLRLSEEDGQSVLRYIRGNESLADIVVYI
ISGATEVASLTSGQGLERIDGFFEKPLNLPKLLDTVSAVVRPSRRAPAVP
>Mature_530_residues
MEADVAHRALLEMSRHLTDNAGPTEALRAHLQTIHTLLKPKVCYVARYFPSREQLHVEHVRGRYDDRVTAAVPGEGVVGR
AFSQKALLRDGDTVAVPLEGPQGVGGVLVVLGSRREPSDTLLQSLAAQLTAAYEVARLRDDSARRNKDLQTAIAGLKSLE
QNREELLGNVSHDLKNPLTTIKSYLAMMGREKLGPLTDAQRRAVQICDRNSDRMLRMVNDLLLMSRLQSGKMQLNQRPFG
LKAVAEEVVRSLGALAEHCKVRVVIPPCPEVFVRGDRERIAEAIHNLVENGIHHSEADDTVEVRVSAEDGLAMLTVKDSG
PGMSSEALEHVFDAFYRATPGMPRPPGAGLGLPLVGKIVALHGGRMESASVLGEGSTFQMVLPMFAGAVSAPEMAQAAPK
SGGILLVEDDADCREVLQQVLEQEGYRVMATSGASEARSILSHIRPAMVLLDLRLSEEDGQSVLRYIRGNESLADIVVYI
ISGATEVASLTSGQGLERIDGFFEKPLNLPKLLDTVSAVVRPSRRAPAVP

Specific function: Member of the two-component regulatory system YycG/YycF involved in the regulation of the ftsAZ operon, the yocH and ykvT, cwlO, lytE, ydjM, yjeA, yoeB genes and the tagAB and tagDEF operons. Probably phosphorylates YycF [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1786600, Length=233, Percent_Identity=29.1845493562232, Blast_Score=99, Evalue=1e-21,
Organism=Escherichia coli, GI1788393, Length=253, Percent_Identity=26.8774703557312, Blast_Score=92, Evalue=9e-20,
Organism=Escherichia coli, GI1789149, Length=225, Percent_Identity=29.7777777777778, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI145693157, Length=290, Percent_Identity=24.1379310344828, Blast_Score=90, Evalue=3e-19,
Organism=Escherichia coli, GI87081816, Length=318, Percent_Identity=24.5283018867925, Blast_Score=89, Evalue=7e-19,
Organism=Escherichia coli, GI1790346, Length=236, Percent_Identity=27.1186440677966, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1786912, Length=240, Percent_Identity=29.1666666666667, Blast_Score=83, Evalue=5e-17,
Organism=Escherichia coli, GI1788713, Length=344, Percent_Identity=21.8023255813953, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI1788549, Length=222, Percent_Identity=23.8738738738739, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1790436, Length=224, Percent_Identity=28.125, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI48994928, Length=377, Percent_Identity=24.1379310344828, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1786783, Length=221, Percent_Identity=26.2443438914027, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1789808, Length=231, Percent_Identity=27.2727272727273, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1789403, Length=204, Percent_Identity=28.4313725490196, Blast_Score=65, Evalue=9e-12,
Organism=Escherichia coli, GI1787894, Length=237, Percent_Identity=24.0506329113924, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI87082128, Length=233, Percent_Identity=24.0343347639485, Blast_Score=63, Evalue=4e-11,
Organism=Escherichia coli, GI1790551, Length=229, Percent_Identity=25.3275109170306, Blast_Score=62, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 57470; Mature: 57470

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEADVAHRALLEMSRHLTDNAGPTEALRAHLQTIHTLLKPKVCYVARYFPSREQLHVEHV
CCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHCCCHHHHHHHHH
RGRYDDRVTAAVPGEGVVGRAFSQKALLRDGDTVAVPLEGPQGVGGVLVVLGSRREPSDT
CCCCCCCEEEECCCCCCCCHHHHHHHHHCCCCEEEEECCCCCCCCCEEEEECCCCCCHHH
LLQSLAAQLTAAYEVARLRDDSARRNKDLQTAIAGLKSLEQNREELLGNVSHDLKNPLTT
HHHHHHHHHHHHHHHHHHCCCHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IKSYLAMMGREKLGPLTDAQRRAVQICDRNSDRMLRMVNDLLLMSRLQSGKMQLNQRPFG
HHHHHHHHHHHHCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCHHHCCCCCC
LKAVAEEVVRSLGALAEHCKVRVVIPPCPEVFVRGDRERIAEAIHNLVENGIHHSEADDT
HHHHHHHHHHHHHHHHHHCEEEEEECCCCHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCE
VEVRVSAEDGLAMLTVKDSGPGMSSEALEHVFDAFYRATPGMPRPPGAGLGLPLVGKIVA
EEEEEECCCCEEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHH
LHGGRMESASVLGEGSTFQMVLPMFAGAVSAPEMAQAAPKSGGILLVEDDADCREVLQQV
HCCCCCCHHHHHCCCCHHHHHHHHHHCCCCCCHHHHCCCCCCCEEEEECCHHHHHHHHHH
LEQEGYRVMATSGASEARSILSHIRPAMVLLDLRLSEEDGQSVLRYIRGNESLADIVVYI
HHHCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHH
ISGATEVASLTSGQGLERIDGFFEKPLNLPKLLDTVSAVVRPSRRAPAVP
HHCCHHHHHHCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MEADVAHRALLEMSRHLTDNAGPTEALRAHLQTIHTLLKPKVCYVARYFPSREQLHVEHV
CCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHCCCHHHHHHHHH
RGRYDDRVTAAVPGEGVVGRAFSQKALLRDGDTVAVPLEGPQGVGGVLVVLGSRREPSDT
CCCCCCCEEEECCCCCCCCHHHHHHHHHCCCCEEEEECCCCCCCCCEEEEECCCCCCHHH
LLQSLAAQLTAAYEVARLRDDSARRNKDLQTAIAGLKSLEQNREELLGNVSHDLKNPLTT
HHHHHHHHHHHHHHHHHHCCCHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IKSYLAMMGREKLGPLTDAQRRAVQICDRNSDRMLRMVNDLLLMSRLQSGKMQLNQRPFG
HHHHHHHHHHHHCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCHHHCCCCCC
LKAVAEEVVRSLGALAEHCKVRVVIPPCPEVFVRGDRERIAEAIHNLVENGIHHSEADDT
HHHHHHHHHHHHHHHHHHCEEEEEECCCCHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCE
VEVRVSAEDGLAMLTVKDSGPGMSSEALEHVFDAFYRATPGMPRPPGAGLGLPLVGKIVA
EEEEEECCCCEEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHH
LHGGRMESASVLGEGSTFQMVLPMFAGAVSAPEMAQAAPKSGGILLVEDDADCREVLQQV
HCCCCCCHHHHHCCCCHHHHHHHHHHCCCCCCHHHHCCCCCCCEEEEECCHHHHHHHHHH
LEQEGYRVMATSGASEARSILSHIRPAMVLLDLRLSEEDGQSVLRYIRGNESLADIVVYI
HHHCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHH
ISGATEVASLTSGQGLERIDGFFEKPLNLPKLLDTVSAVVRPSRRAPAVP
HHCCHHHHHHCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377; 9829949; 10878122; 11758928 [H]