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The map label for this gene is eryA [H]

Identifier: 108761430

GI number: 108761430

Start: 5633013

End: 5638601

Strand: Reverse

Name: eryA [H]

Synonym: MXAN_4529

Alternate gene names: 108761430

Gene position: 5638601-5633013 (Counterclockwise)

Preceding gene: 108760644

Following gene: 108760271

Centisome position: 61.69

GC content: 70.82

Gene sequence:

>5589_bases
ATGACGACGTTCGCGGAGAAGATTGCGCAGTACTCCCCCAAGCGGCTCGCGCTGCTGGCGATGGACCTCAAGTCGCGGCT
CGACGCGGTGGAGGGCAGCCGGTCGGAGCCCGTGGCCATCATCGGCATGGGCTGCCGCTTCCCGGGCGGAGGGAACGACC
CGGCGTCGTACTGGAACCTCCTGTGCAACGGCGTGGATGCCGTCACCGAGGTGCCATCCTCGCGGTGGACCCGTGAGGAC
ATGGCGCGGATGGACCCCGAGGCCCAGGAGAAGCTGGGCGCGAAGTGGGGTGCCTTCATCAACGCGGTGGACCAGTTCGA
CGCGGATTTCTTCGGCATCTCTCCGCACGAAGCGCACCGGATGGACCCGCAGCAGCGCATCCTCCTGGAAGTGGCGTGGG
AGGCGCTGGAGAACGCGGGCCAGGACATGTCTCGGCTGGCAGGGAGCCGCACGGGCGTGTTCGTGGGCGTGTACAGCGAT
GACTACGCGCTGTTGCAGGTGGGAAATCCGGCGGCGCGCGACTCCAGCAGTGTGACGGGCGCCATCAACTGCGTGGTGCC
GGGGCGGCTGTCGTACCTCCTGGACTTCCAGGGACCCAGCCTGTCCGTGGACACCGCGTGTTCGTCATCCCTGGTGGCGC
TGCATCTGGCCGCGCAGAGCCTCCGGCAGCAAGAGTGCACCATGGCGCTGGCGTGCGGCGTCAACCTCATCCTGTCGCCG
CTGTCGTCGAGCCGCGTGTCCCGTGCGCAGGCGCTCGCGCCGGATGGACGCTGCAAGACCTTCGATGCCCGCGCCAACGG
CTTCGTGCGGGGCGAGGGCTGCGGCGTGGTCGTCCTCAAGCGGCTGTCGGATGCGCTGGCGGCGGGGGACACCGTCCTAG
CGCTCATCCGGGGGTCTGCCGTCAACCAGGATGGCAAGTCGGCGGGATTGACGGCGCCCAACGTGCTCGCGCAGAAGGCG
CTCATCCGCCAGGCGCTCCAGAGCGCGAACCTGGAGCCCGCCGACATCGACTGCGTTGAGGCCCATGGCACCGGGACGTC
GCTGGGCGACCCCATCGAGCTGGAGGCGCTCCACGAGGTGTACGCCCAGGGGCGCACCGCGGAGCAGTCGCTGGTGGTGG
GCGCGGCGAAGACGAACATCGGCCACCTGGAGTCGGCCGCCGGCATCGCTGGCATCATCAAGATGGTCCTGTCGATGCAG
CACGGGGCCGTCCCGCCGCTCGCGCACTTCCAGCGGCTCAACCCGCGCATCGACTTCGGCGGTGAGGCCCTCACTGTCCC
TACGAAGCTGCACCCCTGGCCCGCGCGGGAGACGCGCAAGCGCCGGGGGGCGGTCAGCTCGTTTGGCATCAGCGGCACGA
ATGCCCATGTGATTCTCGAAGAGGCCCCCGTGGCCGCGGCGGCGCCCGCTGCGCCTTCTCGCGGGGCGTACCTGCTGCCG
CTGTCCGCGCGCTCACCCTCCGCGCTTCAAGCATTGGCCCGGAAGTACGCGGACGTCCTCACGTCGTCCCCGGAGATGTC
GCTCCGGGATGTCTGCTTCACCGCGGCGCTGCGGCGGACCCATCACGAGTACCGGACGGCGGTCGCGGGGGACTCGGCGG
ACGCTGTGGCGCGGCAGCTTCGGGAGTTCGCCTTGGAGGGGCCTGCTCCGGCGGCGACGGACACGGATACCCGGCGCAAG
GCGGTCTTCGTGTTCCCGGGGCAGGGCTCGCAGTGGGCCGGCATGGGGCGGCAGCTCCTCGAACAGGAGCCTGTCTTCCG
TGAGGCCGTGGAGCGCATCGACGAGGCCATGCGGCCCCACGTCACGTGGCGTCTGATTGACGTGCTGCGCGCCCCTGCCG
AGGACTCCCGGCTCCAGGACATCGACGTCGTGCAGCCGGTGTTGTTCGCCATGGCGGTGGCGCTGTCCGCACTCTGGCGC
TCCTGGGGCGTCGAGCCGGACGCGGTGGTGGGGCACAGCATGGGCGAGGTGGCCGCGGCGCACGTCGCGGGCGCGCTCTC
CCTGGAGGACGCGGCGCGCATCATCTGCCTGCGCAGCCAGCTCCTGCGGCGCATCAGCGGCCAGGGGGCCATGCTCGCGA
CGGAGCTGACCCTGGAGGACGCGCGCAAGACGCTGGCGGGCCGCGAGGACCGCGTGGCCATCGCGGTCAGCAACAGTCCG
ACCTCCACGGTGCTGTCGGGAGAGAATGCCGCGCTCGAATCGATTCGCGCCGACCTGGAGTCGCGCAACGTCTTCTGCCG
CTGGGTGAAGGTCGACGTCGCCTCGCACAGTCCGCAGGTGGACCCGCTGCGGGACGAGCTGCTCTCGGTGCTCTCGGCGG
TGCGGCCCGGACGCTCCAGCGTGCCCATTCACTCCACGGTGACCGGCGCCTCCTGTGACGGCTCCGGCTTCGATGCCGCC
TACTGGGTCCGCAATCTGCGCGACCCGGTGCTCTTCTCCTCGTCGGTGCTGCAACTCGCCGAGGCTGGGCACTCCGTTTT
CCTGGAGATGAGCCCGCACCCGATTCTGCTGCCCGCTGTGGAGCGATGCCTGCAGCACGCGGGCCGCGAGGGCGTGACGC
TTCCGTCCCTGCGCCGCGAGGAGGCTGAGCGGACCGTGCTGCTGGAGTCCGTGGGCGCGCTGTACCGCGCGGGACTCCCC
GTGCAGTGGAAGCGCTTCTTCCCGGGGGGTGGGACGCCGCTCCCGCTGCCCACCTATCCCTGGCAGCACAAGCGGTACTG
GTTGGACGCGGTGGCCACGCCCGTGGCCGCGATGGTCGAGCCGGTGACGTCCCTCAAGGGCCGGCCGGTGAGCGTGGCTC
ACGGCGTCGATGGCCAGGTCTTCGAGCTGGAGCTGGGGAGCAACTCGCTGCCGTGGCTTGGTGCTCACCGGTTGGGTGGC
GTCGCGGTCGTTCCTGCCTCGGCGTTGGTGGAGCTCGGGCTGAGCGCCGCCGCCGATGCGTTGGGCCCTGGGGGACGGGG
GCTGTCCGGCGTCGAGTTCGAGCGGGCGCTGGTGCTGCCGGAGACCCCGCGGCGGCTCGTGCAGGTCCACCTCTCTTCCG
AGGCAGGAGGCAAGCACGAGTTCCACATCCACAGCCGCGCGGTGGGCGGGGCCTCGTCCGAGGCGGGGTGGGTGCGGCAT
TGCCGGGGCCATGTCCAGGTGCTCAGTGCCGCGATGGGCGCGTTGGCGTCCATCGACGCGGTCCGTGCGCGCTGTGTGGA
GCACGTCCCGGGCGCGGCGGTCTACGGCGAGCTGGAGCGCTGCAACGTCCAGTACGACGAGCCGCTGCGGACACTGGACG
AGGCGTGGCGGCGGCCGGGGGAGGCGCTGGGCCGGGTGGTGCTGGGCGCGGAGCGACTTCAGGAGGCGTCCCAGTATCAG
TTGCATCCCGCGTTGCTGGACGCCGCGCTCCAGACGCTGGCGCTCGCGCTGGCGGCCGAACCGGGGCAGGCGGCGCTCTT
CATGCCCCTGGGGCTCGAATCATTCGAGTGCGTCCCTGGCAGCGCGGACGTTCGGTGGGCTCACGTCTCCATTTCGCCCG
CGTCTCGTCCTGAGGAGCGGCTGGGCACATTGTCCCTGCTGGACGCGGAGGGTCGCCCGGTCGCGGTGGCGCGCGGTGTC
CGGTTGCGGCACGTGGCGGTGGAGCGGCTGCTCGAGGTGTTGGGGGAAGTCCGCGCGCAGGACTGGTTCCACGACGTGTC
GTGGGAGCCGCGGCCGGCGGGGACACCCCAGTCGGCCCCCGCGGATTGGCTTGTGTTCGCGGACCGGGGTGGTTGGGGCG
CGGCATTCGCCGAGGAGCTGCGGCGTCAGAACACCCCTTTTGTCATGGTGACCGCGGGGGACGCCTTCCAGCGCCTGGGA
ACGCGGAGCTTCGTGGTGGACCCACAGCGGCCGGAGGACATGGCGCGCTTGCTGCGAGAGCTTCCAGCGCTCGCGGCTGG
GCACGAAGGCCGGGCGCTCTTCCTGTGGGGCCTCGACGAAACGTTGGATGGGCAGACGGCAGTGCCCGCGTCCACGGTGG
CGGCGCTGCACCTGGTGAAGGCCCTCATGGAGGTGTCAGGGCATGCGCGGCTTTGGGTGGTGACGCGGGGCGCGCAGGTC
ACGGGCGTGGGAACCGAACGTGTGTCGCTGGCCCAGTCACCCCTTTGGGGCATGGGCCGGAGCGTCTCGCTGGAACAGCC
GGGCGTTTGGGGCGGCCTCATCGACCTGCCGCCGACTCGGTCGCCGGATGAAGTCACCTCGGTGCTGCGGGAAGTCTCCG
CGTTCGGAACGGATGGAGAGGACCAGTTCGCCTTCCGCGATGGGCGCTCGCTGGTCCCCCGGCTTACACGGGGAAGGGCA
GGGACGGCCGAGGAGGCACTGCGCCTGCGCTCGGATGCGACGTACCTGGTCTCGGGCGGCCTGGGCGGGCTGGGGCTGAA
GGTGGCGCGGTGGCTGGTGGAGCGGGGCGCGCGGCACCTGGTGCTGCTGGGCCGCAGTGGGGTCTCCGGTGCGGACGATG
CGGCGTCGGTGCGGCGCCGCGAGGAGCTCGAGTCGATCCGGGTGATCGGGGCGACTGTCACGCCCATGGCCGTGGACGTA
GCGGACCGCGAGCGGATGGCGGCGCTCCTGCGCGACATGGCGGCGACGCTGCCTCCGTTGCGCGGCGTGATTCATGCCGC
CGCGCTCATCACGGAGTGCCGGTTGGAGGACCTGGATGTCGCCGCCACGACGGCGATGATGCGTCCGAAGGTGCTCGGGA
GCTGGGTGTTGCACGACCTGACGCGCGGCCTCTCGCTCGACTTCTTCGTGATGTTCTCGTCGACGTCCACGTTGTGGGGC
GCTTCCGGCTTGGCGCATTACGCGGCGGGCAACCAGTTCCTGGAAGCGCTGGCGCATCACCGCCGGGCCGAAGGGCTGCC
CGCGACCACCATTCACTGGGGGACGTGGGACGAGATTGGCGGAGAGCGCGCCGACAACGCGCGGGGCTACGCCCGCTTCG
GGCTGAACCCCATGGCCTCGGAGCGCGCGCTCGATGCGATGGGACAGGTGCTGCGGTCGGGCGCGAGCCATAAGACGGTC
GCCTCCGTGGACTGGTCCGTACTCAAGCCCATCTGGGAGGCTCGGCGTCGCCGGCCCTTCCTGCTGAACATGGGCGCGGC
GTCGCTGGCCACGAACGGTGGTGCCACTTCGCGGGCACGGTTGCTCTCGGAGTTGAAGGCGCTCCCTGCTGAGCGCCGGT
TCGACACGCTCGTGCAACGCATCCAGGGCGAGGTGGGGCGCATTCTCGGCTTCGCTCCCGCCGACTTGCCCCCCGTGGAC
CGCGGCTTCTTCCAGATGGGGATGACGTCCCAGATGTCCGTGGAGCTGCGCAACGTGTTGCAGCGCGGACTCGAGAAGGA
GCTGCCCGCGAGCCTCGCGTTCGACCACCCCACCGTCGTGGCGCTGGCGAAGCGCCTGGCGGGGAGCGTCACCGCGGTGG
ACATCCCGTTGCCCACGGTGGCGGCGGCTCCGGTGCAGAAGTCATCCCCGGTGCCTGCGGACGTCGGCGACCTGTCGGAG
CGGCTGGCGCAAGTCTCGGAGCTGTCGGACGACGAAGTCGAGCGGTTGATTGCCCTGAAGTTGAGCTGA

Upstream 100 bases:

>100_bases
CGGTGAAGGCCTCCCAGGCGGATGTGACGGCCAGCGAGATTGACGACCTGTCGGAAGAGGAAGTCGAGCGGCTGTTCGCT
CAGAGGATGGCGCAAGGCTC

Downstream 100 bases:

>100_bases
ATCGGACGACTGCGATGAGCAAGGAATTCTACGAGAAGATTTCGAACCTCTCTCCCAAGAGGCTCGCGCTGCTGGCGCTC
GACCTGCACGCGGAGAGCGA

Product: polyketide synthase type I

Products: NA

Alternate protein names: 6-deoxyerythronolide B synthase II; DEBS 2; ORF 2 [H]

Number of amino acids: Translated: 1862; Mature: 1861

Protein sequence:

>1862_residues
MTTFAEKIAQYSPKRLALLAMDLKSRLDAVEGSRSEPVAIIGMGCRFPGGGNDPASYWNLLCNGVDAVTEVPSSRWTRED
MARMDPEAQEKLGAKWGAFINAVDQFDADFFGISPHEAHRMDPQQRILLEVAWEALENAGQDMSRLAGSRTGVFVGVYSD
DYALLQVGNPAARDSSSVTGAINCVVPGRLSYLLDFQGPSLSVDTACSSSLVALHLAAQSLRQQECTMALACGVNLILSP
LSSSRVSRAQALAPDGRCKTFDARANGFVRGEGCGVVVLKRLSDALAAGDTVLALIRGSAVNQDGKSAGLTAPNVLAQKA
LIRQALQSANLEPADIDCVEAHGTGTSLGDPIELEALHEVYAQGRTAEQSLVVGAAKTNIGHLESAAGIAGIIKMVLSMQ
HGAVPPLAHFQRLNPRIDFGGEALTVPTKLHPWPARETRKRRGAVSSFGISGTNAHVILEEAPVAAAAPAAPSRGAYLLP
LSARSPSALQALARKYADVLTSSPEMSLRDVCFTAALRRTHHEYRTAVAGDSADAVARQLREFALEGPAPAATDTDTRRK
AVFVFPGQGSQWAGMGRQLLEQEPVFREAVERIDEAMRPHVTWRLIDVLRAPAEDSRLQDIDVVQPVLFAMAVALSALWR
SWGVEPDAVVGHSMGEVAAAHVAGALSLEDAARIICLRSQLLRRISGQGAMLATELTLEDARKTLAGREDRVAIAVSNSP
TSTVLSGENAALESIRADLESRNVFCRWVKVDVASHSPQVDPLRDELLSVLSAVRPGRSSVPIHSTVTGASCDGSGFDAA
YWVRNLRDPVLFSSSVLQLAEAGHSVFLEMSPHPILLPAVERCLQHAGREGVTLPSLRREEAERTVLLESVGALYRAGLP
VQWKRFFPGGGTPLPLPTYPWQHKRYWLDAVATPVAAMVEPVTSLKGRPVSVAHGVDGQVFELELGSNSLPWLGAHRLGG
VAVVPASALVELGLSAAADALGPGGRGLSGVEFERALVLPETPRRLVQVHLSSEAGGKHEFHIHSRAVGGASSEAGWVRH
CRGHVQVLSAAMGALASIDAVRARCVEHVPGAAVYGELERCNVQYDEPLRTLDEAWRRPGEALGRVVLGAERLQEASQYQ
LHPALLDAALQTLALALAAEPGQAALFMPLGLESFECVPGSADVRWAHVSISPASRPEERLGTLSLLDAEGRPVAVARGV
RLRHVAVERLLEVLGEVRAQDWFHDVSWEPRPAGTPQSAPADWLVFADRGGWGAAFAEELRRQNTPFVMVTAGDAFQRLG
TRSFVVDPQRPEDMARLLRELPALAAGHEGRALFLWGLDETLDGQTAVPASTVAALHLVKALMEVSGHARLWVVTRGAQV
TGVGTERVSLAQSPLWGMGRSVSLEQPGVWGGLIDLPPTRSPDEVTSVLREVSAFGTDGEDQFAFRDGRSLVPRLTRGRA
GTAEEALRLRSDATYLVSGGLGGLGLKVARWLVERGARHLVLLGRSGVSGADDAASVRRREELESIRVIGATVTPMAVDV
ADRERMAALLRDMAATLPPLRGVIHAAALITECRLEDLDVAATTAMMRPKVLGSWVLHDLTRGLSLDFFVMFSSTSTLWG
ASGLAHYAAGNQFLEALAHHRRAEGLPATTIHWGTWDEIGGERADNARGYARFGLNPMASERALDAMGQVLRSGASHKTV
ASVDWSVLKPIWEARRRRPFLLNMGAASLATNGGATSRARLLSELKALPAERRFDTLVQRIQGEVGRILGFAPADLPPVD
RGFFQMGMTSQMSVELRNVLQRGLEKELPASLAFDHPTVVALAKRLAGSVTAVDIPLPTVAAAPVQKSSPVPADVGDLSE
RLAQVSELSDDEVERLIALKLS

Sequences:

>Translated_1862_residues
MTTFAEKIAQYSPKRLALLAMDLKSRLDAVEGSRSEPVAIIGMGCRFPGGGNDPASYWNLLCNGVDAVTEVPSSRWTRED
MARMDPEAQEKLGAKWGAFINAVDQFDADFFGISPHEAHRMDPQQRILLEVAWEALENAGQDMSRLAGSRTGVFVGVYSD
DYALLQVGNPAARDSSSVTGAINCVVPGRLSYLLDFQGPSLSVDTACSSSLVALHLAAQSLRQQECTMALACGVNLILSP
LSSSRVSRAQALAPDGRCKTFDARANGFVRGEGCGVVVLKRLSDALAAGDTVLALIRGSAVNQDGKSAGLTAPNVLAQKA
LIRQALQSANLEPADIDCVEAHGTGTSLGDPIELEALHEVYAQGRTAEQSLVVGAAKTNIGHLESAAGIAGIIKMVLSMQ
HGAVPPLAHFQRLNPRIDFGGEALTVPTKLHPWPARETRKRRGAVSSFGISGTNAHVILEEAPVAAAAPAAPSRGAYLLP
LSARSPSALQALARKYADVLTSSPEMSLRDVCFTAALRRTHHEYRTAVAGDSADAVARQLREFALEGPAPAATDTDTRRK
AVFVFPGQGSQWAGMGRQLLEQEPVFREAVERIDEAMRPHVTWRLIDVLRAPAEDSRLQDIDVVQPVLFAMAVALSALWR
SWGVEPDAVVGHSMGEVAAAHVAGALSLEDAARIICLRSQLLRRISGQGAMLATELTLEDARKTLAGREDRVAIAVSNSP
TSTVLSGENAALESIRADLESRNVFCRWVKVDVASHSPQVDPLRDELLSVLSAVRPGRSSVPIHSTVTGASCDGSGFDAA
YWVRNLRDPVLFSSSVLQLAEAGHSVFLEMSPHPILLPAVERCLQHAGREGVTLPSLRREEAERTVLLESVGALYRAGLP
VQWKRFFPGGGTPLPLPTYPWQHKRYWLDAVATPVAAMVEPVTSLKGRPVSVAHGVDGQVFELELGSNSLPWLGAHRLGG
VAVVPASALVELGLSAAADALGPGGRGLSGVEFERALVLPETPRRLVQVHLSSEAGGKHEFHIHSRAVGGASSEAGWVRH
CRGHVQVLSAAMGALASIDAVRARCVEHVPGAAVYGELERCNVQYDEPLRTLDEAWRRPGEALGRVVLGAERLQEASQYQ
LHPALLDAALQTLALALAAEPGQAALFMPLGLESFECVPGSADVRWAHVSISPASRPEERLGTLSLLDAEGRPVAVARGV
RLRHVAVERLLEVLGEVRAQDWFHDVSWEPRPAGTPQSAPADWLVFADRGGWGAAFAEELRRQNTPFVMVTAGDAFQRLG
TRSFVVDPQRPEDMARLLRELPALAAGHEGRALFLWGLDETLDGQTAVPASTVAALHLVKALMEVSGHARLWVVTRGAQV
TGVGTERVSLAQSPLWGMGRSVSLEQPGVWGGLIDLPPTRSPDEVTSVLREVSAFGTDGEDQFAFRDGRSLVPRLTRGRA
GTAEEALRLRSDATYLVSGGLGGLGLKVARWLVERGARHLVLLGRSGVSGADDAASVRRREELESIRVIGATVTPMAVDV
ADRERMAALLRDMAATLPPLRGVIHAAALITECRLEDLDVAATTAMMRPKVLGSWVLHDLTRGLSLDFFVMFSSTSTLWG
ASGLAHYAAGNQFLEALAHHRRAEGLPATTIHWGTWDEIGGERADNARGYARFGLNPMASERALDAMGQVLRSGASHKTV
ASVDWSVLKPIWEARRRRPFLLNMGAASLATNGGATSRARLLSELKALPAERRFDTLVQRIQGEVGRILGFAPADLPPVD
RGFFQMGMTSQMSVELRNVLQRGLEKELPASLAFDHPTVVALAKRLAGSVTAVDIPLPTVAAAPVQKSSPVPADVGDLSE
RLAQVSELSDDEVERLIALKLS
>Mature_1861_residues
TTFAEKIAQYSPKRLALLAMDLKSRLDAVEGSRSEPVAIIGMGCRFPGGGNDPASYWNLLCNGVDAVTEVPSSRWTREDM
ARMDPEAQEKLGAKWGAFINAVDQFDADFFGISPHEAHRMDPQQRILLEVAWEALENAGQDMSRLAGSRTGVFVGVYSDD
YALLQVGNPAARDSSSVTGAINCVVPGRLSYLLDFQGPSLSVDTACSSSLVALHLAAQSLRQQECTMALACGVNLILSPL
SSSRVSRAQALAPDGRCKTFDARANGFVRGEGCGVVVLKRLSDALAAGDTVLALIRGSAVNQDGKSAGLTAPNVLAQKAL
IRQALQSANLEPADIDCVEAHGTGTSLGDPIELEALHEVYAQGRTAEQSLVVGAAKTNIGHLESAAGIAGIIKMVLSMQH
GAVPPLAHFQRLNPRIDFGGEALTVPTKLHPWPARETRKRRGAVSSFGISGTNAHVILEEAPVAAAAPAAPSRGAYLLPL
SARSPSALQALARKYADVLTSSPEMSLRDVCFTAALRRTHHEYRTAVAGDSADAVARQLREFALEGPAPAATDTDTRRKA
VFVFPGQGSQWAGMGRQLLEQEPVFREAVERIDEAMRPHVTWRLIDVLRAPAEDSRLQDIDVVQPVLFAMAVALSALWRS
WGVEPDAVVGHSMGEVAAAHVAGALSLEDAARIICLRSQLLRRISGQGAMLATELTLEDARKTLAGREDRVAIAVSNSPT
STVLSGENAALESIRADLESRNVFCRWVKVDVASHSPQVDPLRDELLSVLSAVRPGRSSVPIHSTVTGASCDGSGFDAAY
WVRNLRDPVLFSSSVLQLAEAGHSVFLEMSPHPILLPAVERCLQHAGREGVTLPSLRREEAERTVLLESVGALYRAGLPV
QWKRFFPGGGTPLPLPTYPWQHKRYWLDAVATPVAAMVEPVTSLKGRPVSVAHGVDGQVFELELGSNSLPWLGAHRLGGV
AVVPASALVELGLSAAADALGPGGRGLSGVEFERALVLPETPRRLVQVHLSSEAGGKHEFHIHSRAVGGASSEAGWVRHC
RGHVQVLSAAMGALASIDAVRARCVEHVPGAAVYGELERCNVQYDEPLRTLDEAWRRPGEALGRVVLGAERLQEASQYQL
HPALLDAALQTLALALAAEPGQAALFMPLGLESFECVPGSADVRWAHVSISPASRPEERLGTLSLLDAEGRPVAVARGVR
LRHVAVERLLEVLGEVRAQDWFHDVSWEPRPAGTPQSAPADWLVFADRGGWGAAFAEELRRQNTPFVMVTAGDAFQRLGT
RSFVVDPQRPEDMARLLRELPALAAGHEGRALFLWGLDETLDGQTAVPASTVAALHLVKALMEVSGHARLWVVTRGAQVT
GVGTERVSLAQSPLWGMGRSVSLEQPGVWGGLIDLPPTRSPDEVTSVLREVSAFGTDGEDQFAFRDGRSLVPRLTRGRAG
TAEEALRLRSDATYLVSGGLGGLGLKVARWLVERGARHLVLLGRSGVSGADDAASVRRREELESIRVIGATVTPMAVDVA
DRERMAALLRDMAATLPPLRGVIHAAALITECRLEDLDVAATTAMMRPKVLGSWVLHDLTRGLSLDFFVMFSSTSTLWGA
SGLAHYAAGNQFLEALAHHRRAEGLPATTIHWGTWDEIGGERADNARGYARFGLNPMASERALDAMGQVLRSGASHKTVA
SVDWSVLKPIWEARRRRPFLLNMGAASLATNGGATSRARLLSELKALPAERRFDTLVQRIQGEVGRILGFAPADLPPVDR
GFFQMGMTSQMSVELRNVLQRGLEKELPASLAFDHPTVVALAKRLAGSVTAVDIPLPTVAAAPVQKSSPVPADVGDLSER
LAQVSELSDDEVERLIALKLS

Specific function: Catalyzes The Condensation Reaction Of Fatty Acid Synthesis By The Addition To An Acyl Acceptor Of Two Carbons From Malonyl-Acp. Has A Preference For Short Chain Acid Substrates And May Function To Supply The Octanoic Substrates For Lipoic Acid Biosynthe

COG id: COG3321

COG function: function code Q; Polyketide synthase modules and related proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 acyl carrier domains [H]

Homologues:

Organism=Homo sapiens, GI41872631, Length=1008, Percent_Identity=31.3492063492063, Blast_Score=372, Evalue=1e-102,
Organism=Homo sapiens, GI8923559, Length=279, Percent_Identity=30.1075268817204, Blast_Score=108, Evalue=5e-23,
Organism=Homo sapiens, GI310129082, Length=107, Percent_Identity=38.3177570093458, Blast_Score=74, Evalue=2e-12,
Organism=Homo sapiens, GI310109937, Length=107, Percent_Identity=38.3177570093458, Blast_Score=74, Evalue=2e-12,
Organism=Homo sapiens, GI239744023, Length=107, Percent_Identity=38.3177570093458, Blast_Score=74, Evalue=2e-12,
Organism=Escherichia coli, GI1787337, Length=381, Percent_Identity=26.7716535433071, Blast_Score=99, Evalue=3e-21,
Organism=Escherichia coli, GI1787334, Length=304, Percent_Identity=29.9342105263158, Blast_Score=94, Evalue=6e-20,
Organism=Escherichia coli, GI1788663, Length=292, Percent_Identity=26.7123287671233, Blast_Score=85, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI212642053, Length=980, Percent_Identity=28.6734693877551, Blast_Score=375, Evalue=1e-103,
Organism=Caenorhabditis elegans, GI17550940, Length=499, Percent_Identity=34.8697394789579, Blast_Score=266, Evalue=1e-70,
Organism=Caenorhabditis elegans, GI71983541, Length=284, Percent_Identity=29.9295774647887, Blast_Score=119, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI71983535, Length=264, Percent_Identity=31.0606060606061, Blast_Score=117, Evalue=8e-26,
Organism=Saccharomyces cerevisiae, GI6320904, Length=445, Percent_Identity=26.2921348314607, Blast_Score=119, Evalue=4e-27,
Organism=Drosophila melanogaster, GI221330659, Length=986, Percent_Identity=30.6288032454361, Blast_Score=367, Evalue=1e-101,
Organism=Drosophila melanogaster, GI19920632, Length=985, Percent_Identity=30.6598984771574, Blast_Score=367, Evalue=1e-101,
Organism=Drosophila melanogaster, GI24581345, Length=988, Percent_Identity=29.6558704453441, Blast_Score=337, Evalue=7e-92,
Organism=Drosophila melanogaster, GI24644341, Length=281, Percent_Identity=31.6725978647687, Blast_Score=100, Evalue=9e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001227
- InterPro:   IPR009081
- InterPro:   IPR014043
- InterPro:   IPR016035
- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR000794
- InterPro:   IPR002198
- InterPro:   IPR015357
- InterPro:   IPR011032
- InterPro:   IPR018201
- InterPro:   IPR014031
- InterPro:   IPR014030
- InterPro:   IPR016036
- InterPro:   IPR016040
- InterPro:   IPR006163
- InterPro:   IPR020842
- InterPro:   IPR020801
- InterPro:   IPR020841
- InterPro:   IPR020807
- InterPro:   IPR020843
- InterPro:   IPR020806
- InterPro:   IPR015083
- InterPro:   IPR006162
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF00698 Acyl_transf_1; PF08240 ADH_N; PF00106 adh_short; PF00107 ADH_zinc_N; PF08990 Docking; PF09277 Erythro-docking; PF00109 ketoacyl-synt; PF02801 Ketoacyl-synt_C; PF00550 PP-binding [H]

EC number: =2.3.1.94 [H]

Molecular weight: Translated: 199352; Mature: 199221

Theoretical pI: Translated: 6.59; Mature: 6.59

Prosite motif: PS50075 ACP_DOMAIN ; PS00606 B_KETOACYL_SYNTHASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTFAEKIAQYSPKRLALLAMDLKSRLDAVEGSRSEPVAIIGMGCRFPGGGNDPASYWNL
CCCHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCHHHHHHH
LCNGVDAVTEVPSSRWTREDMARMDPEAQEKLGAKWGAFINAVDQFDADFFGISPHEAHR
HHCCHHHHHHCCCCCCCHHHHHHCCCHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCHHHC
MDPQQRILLEVAWEALENAGQDMSRLAGSRTGVFVGVYSDDYALLQVGNPAARDSSSVTG
CCHHHHHHHHHHHHHHHHCCHHHHHHCCCCCEEEEEEECCCEEEEEECCCCCCCCCCCCE
AINCVVPGRLSYLLDFQGPSLSVDTACSSSLVALHLAAQSLRQQECTMALACGVNLILSP
EEEEEECCCEEEEEECCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHCC
LSSSRVSRAQALAPDGRCKTFDARANGFVRGEGCGVVVLKRLSDALAAGDTVLALIRGSA
CHHHHHHHHHHCCCCCCCEEEECCCCCEEECCCCCHHHHHHHHHHHHCCCHHEEHHHCCC
VNQDGKSAGLTAPNVLAQKALIRQALQSANLEPADIDCVEAHGTGTSLGDPIELEALHEV
CCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCCCCCHHHHHHHHH
YAQGRTAEQSLVVGAAKTNIGHLESAAGIAGIIKMVLSMQHGAVPPLAHFQRLNPRIDFG
HHCCCCCCHHEEEEEHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCC
GEALTVPTKLHPWPARETRKRRGAVSSFGISGTNAHVILEEAPVAAAAPAAPSRGAYLLP
CCEEECCCCCCCCCCHHHHHHCCCCHHCCCCCCCCEEEEECCCCCCCCCCCCCCCEEEEE
LSARSPSALQALARKYADVLTSSPEMSLRDVCFTAALRRTHHEYRTAVAGDSADAVARQL
ECCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
REFALEGPAPAATDTDTRRKAVFVFPGQGSQWAGMGRQLLEQEPVFREAVERIDEAMRPH
HHHHHCCCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHCCC
VTWRLIDVLRAPAEDSRLQDIDVVQPVLFAMAVALSALWRSWGVEPDAVVGHSMGEVAAA
HHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCHHHHHHH
HVAGALSLEDAARIICLRSQLLRRISGQGAMLATELTLEDARKTLAGREDRVAIAVSNSP
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHCCCCCEEEEEECCCC
TSTVLSGENAALESIRADLESRNVFCRWVKVDVASHSPQVDPLRDELLSVLSAVRPGRSS
CCEEECCCHHHHHHHHHHHHCCCEEEEEEEEEECCCCCCCCHHHHHHHHHHHHHCCCCCC
VPIHSTVTGASCDGSGFDAAYWVRNLRDPVLFSSSVLQLAEAGHSVFLEMSPHPILLPAV
CCCEEEECCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHCCCEEEEEECCCCEEHHHH
ERCLQHAGREGVTLPSLRREEAERTVLLESVGALYRAGLPVQWKRFFPGGGTPLPLPTYP
HHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEHEECCCCCCCCCCCCCC
WQHKRYWLDAVATPVAAMVEPVTSLKGRPVSVAHGVDGQVFELELGSNSLPWLGAHRLGG
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCEEEEEEECCCCCCCCCHHHCCC
VAVVPASALVELGLSAAADALGPGGRGLSGVEFERALVLPETPRRLVQVHLSSEAGGKHE
EEEECHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEECCCCCHHHEEEEECCCCCCCEE
FHIHSRAVGGASSEAGWVRHCRGHVQVLSAAMGALASIDAVRARCVEHVPGAAVYGELER
EEEEHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCHHH
CNVQYDEPLRTLDEAWRRPGEALGRVVLGAERLQEASQYQLHPALLDAALQTLALALAAE
CCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PGQAALFMPLGLESFECVPGSADVRWAHVSISPASRPEERLGTLSLLDAEGRPVAVARGV
CCCEEEEEECCCCCCCCCCCCCCEEEEEEEECCCCCCHHHCCCEEEECCCCCCEEECCCC
RLRHVAVERLLEVLGEVRAQDWFHDVSWEPRPAGTPQSAPADWLVFADRGGWGAAFAEEL
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEECCCCCHHHHHHHH
RRQNTPFVMVTAGDAFQRLGTRSFVVDPQRPEDMARLLRELPALAAGHEGRALFLWGLDE
HHCCCCEEEEECCHHHHHCCCCCEEECCCCHHHHHHHHHHHHHHHCCCCCCEEEEEECCC
TLDGQTAVPASTVAALHLVKALMEVSGHARLWVVTRGAQVTGVGTERVSLAQSPLWGMGR
CCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEEECCCEEECCCHHHHHHHCCCCCCCCC
SVSLEQPGVWGGLIDLPPTRSPDEVTSVLREVSAFGTDGEDQFAFRDGRSLVPRLTRGRA
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEECCCCHHHHHHHCCCC
GTAEEALRLRSDATYLVSGGLGGLGLKVARWLVERGARHLVLLGRSGVSGADDAASVRRR
CCHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHCCCCEEEEEECCCCCCCCHHHHHHHH
EELESIRVIGATVTPMAVDVADRERMAALLRDMAATLPPLRGVIHAAALITECRLEDLDV
HHHHHHHHCCCEECCEEEEHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCH
AATTAMMRPKVLGSWVLHDLTRGLSLDFFVMFSSTSTLWGASGLAHYAAGNQFLEALAHH
HHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHH
RRAEGLPATTIHWGTWDEIGGERADNARGYARFGLNPMASERALDAMGQVLRSGASHKTV
HHCCCCCCCEEECCCHHHHCCCCCCCCCCEEECCCCCCHHHHHHHHHHHHHHCCCCCCEE
ASVDWSVLKPIWEARRRRPFLLNMGAASLATNGGATSRARLLSELKALPAERRFDTLVQR
ECCCHHHHHHHHHHHCCCCEEEECCCHHHCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHH
IQGEVGRILGFAPADLPPVDRGFFQMGMTSQMSVELRNVLQRGLEKELPASLAFDHPTVV
HHHHHHHHEECCCCCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHCCCHHCCCCHHHH
ALAKRLAGSVTAVDIPLPTVAAAPVQKSSPVPADVGDLSERLAQVSELSDDEVERLIALK
HHHHHHCCCCEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHEE
LS
CC
>Mature Secondary Structure 
TTFAEKIAQYSPKRLALLAMDLKSRLDAVEGSRSEPVAIIGMGCRFPGGGNDPASYWNL
CCHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCHHHHHHH
LCNGVDAVTEVPSSRWTREDMARMDPEAQEKLGAKWGAFINAVDQFDADFFGISPHEAHR
HHCCHHHHHHCCCCCCCHHHHHHCCCHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCHHHC
MDPQQRILLEVAWEALENAGQDMSRLAGSRTGVFVGVYSDDYALLQVGNPAARDSSSVTG
CCHHHHHHHHHHHHHHHHCCHHHHHHCCCCCEEEEEEECCCEEEEEECCCCCCCCCCCCE
AINCVVPGRLSYLLDFQGPSLSVDTACSSSLVALHLAAQSLRQQECTMALACGVNLILSP
EEEEEECCCEEEEEECCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHCC
LSSSRVSRAQALAPDGRCKTFDARANGFVRGEGCGVVVLKRLSDALAAGDTVLALIRGSA
CHHHHHHHHHHCCCCCCCEEEECCCCCEEECCCCCHHHHHHHHHHHHCCCHHEEHHHCCC
VNQDGKSAGLTAPNVLAQKALIRQALQSANLEPADIDCVEAHGTGTSLGDPIELEALHEV
CCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCCCCCHHHHHHHHH
YAQGRTAEQSLVVGAAKTNIGHLESAAGIAGIIKMVLSMQHGAVPPLAHFQRLNPRIDFG
HHCCCCCCHHEEEEEHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCC
GEALTVPTKLHPWPARETRKRRGAVSSFGISGTNAHVILEEAPVAAAAPAAPSRGAYLLP
CCEEECCCCCCCCCCHHHHHHCCCCHHCCCCCCCCEEEEECCCCCCCCCCCCCCCEEEEE
LSARSPSALQALARKYADVLTSSPEMSLRDVCFTAALRRTHHEYRTAVAGDSADAVARQL
ECCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
REFALEGPAPAATDTDTRRKAVFVFPGQGSQWAGMGRQLLEQEPVFREAVERIDEAMRPH
HHHHHCCCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHCCC
VTWRLIDVLRAPAEDSRLQDIDVVQPVLFAMAVALSALWRSWGVEPDAVVGHSMGEVAAA
HHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCHHHHHHH
HVAGALSLEDAARIICLRSQLLRRISGQGAMLATELTLEDARKTLAGREDRVAIAVSNSP
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHCCCCCEEEEEECCCC
TSTVLSGENAALESIRADLESRNVFCRWVKVDVASHSPQVDPLRDELLSVLSAVRPGRSS
CCEEECCCHHHHHHHHHHHHCCCEEEEEEEEEECCCCCCCCHHHHHHHHHHHHHCCCCCC
VPIHSTVTGASCDGSGFDAAYWVRNLRDPVLFSSSVLQLAEAGHSVFLEMSPHPILLPAV
CCCEEEECCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHCCCEEEEEECCCCEEHHHH
ERCLQHAGREGVTLPSLRREEAERTVLLESVGALYRAGLPVQWKRFFPGGGTPLPLPTYP
HHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEHEECCCCCCCCCCCCCC
WQHKRYWLDAVATPVAAMVEPVTSLKGRPVSVAHGVDGQVFELELGSNSLPWLGAHRLGG
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCEEEEEEECCCCCCCCCHHHCCC
VAVVPASALVELGLSAAADALGPGGRGLSGVEFERALVLPETPRRLVQVHLSSEAGGKHE
EEEECHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEECCCCCHHHEEEEECCCCCCCEE
FHIHSRAVGGASSEAGWVRHCRGHVQVLSAAMGALASIDAVRARCVEHVPGAAVYGELER
EEEEHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCHHH
CNVQYDEPLRTLDEAWRRPGEALGRVVLGAERLQEASQYQLHPALLDAALQTLALALAAE
CCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PGQAALFMPLGLESFECVPGSADVRWAHVSISPASRPEERLGTLSLLDAEGRPVAVARGV
CCCEEEEEECCCCCCCCCCCCCCEEEEEEEECCCCCCHHHCCCEEEECCCCCCEEECCCC
RLRHVAVERLLEVLGEVRAQDWFHDVSWEPRPAGTPQSAPADWLVFADRGGWGAAFAEEL
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEECCCCCHHHHHHHH
RRQNTPFVMVTAGDAFQRLGTRSFVVDPQRPEDMARLLRELPALAAGHEGRALFLWGLDE
HHCCCCEEEEECCHHHHHCCCCCEEECCCCHHHHHHHHHHHHHHHCCCCCCEEEEEECCC
TLDGQTAVPASTVAALHLVKALMEVSGHARLWVVTRGAQVTGVGTERVSLAQSPLWGMGR
CCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEEECCCEEECCCHHHHHHHCCCCCCCCC
SVSLEQPGVWGGLIDLPPTRSPDEVTSVLREVSAFGTDGEDQFAFRDGRSLVPRLTRGRA
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEECCCCHHHHHHHCCCC
GTAEEALRLRSDATYLVSGGLGGLGLKVARWLVERGARHLVLLGRSGVSGADDAASVRRR
CCHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHCCCCEEEEEECCCCCCCCHHHHHHHH
EELESIRVIGATVTPMAVDVADRERMAALLRDMAATLPPLRGVIHAAALITECRLEDLDV
HHHHHHHHCCCEECCEEEEHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCH
AATTAMMRPKVLGSWVLHDLTRGLSLDFFVMFSSTSTLWGASGLAHYAAGNQFLEALAHH
HHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHH
RRAEGLPATTIHWGTWDEIGGERADNARGYARFGLNPMASERALDAMGQVLRSGASHKTV
HHCCCCCCCEEECCCHHHHCCCCCCCCCCEEECCCCCCHHHHHHHHHHHHHHCCCCCCEE
ASVDWSVLKPIWEARRRRPFLLNMGAASLATNGGATSRARLLSELKALPAERRFDTLVQR
ECCCHHHHHHHHHHHCCCCEEEECCCHHHCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHH
IQGEVGRILGFAPADLPPVDRGFFQMGMTSQMSVELRNVLQRGLEKELPASLAFDHPTVV
HHHHHHHHEECCCCCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHCCCHHCCCCHHHH
ALAKRLAGSVTAVDIPLPTVAAAPVQKSSPVPADVGDLSERLAQVSELSDDEVERLIALK
HHHHHHCCCCEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHEE
LS
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2024119; 1740151 [H]