Click here to switch to the map view.

The map label for this gene is mfnA [H]

Identifier: 108761404

GI number: 108761404

Start: 4677504

End: 4679666

Strand: Reverse

Name: mfnA [H]

Synonym: MXAN_3891

Alternate gene names: 108761404

Gene position: 4679666-4677504 (Counterclockwise)

Preceding gene: 108759825

Following gene: 108760634

Centisome position: 51.2

GC content: 60.8

Gene sequence:

>2163_bases
ATGCGGCAGGTAGCGACCGCCAGCAACATTTCAGGACTGGATGGAGCTGGTACCCGCGCAGTGGAAGCGTGGTTCTTGGG
GCCCAAGGGCGAAAACGCGGATGTCTTGGAGTCTCTCATTGTAGAGGCCATTCGGGACCAGGTGTTCTGGCGCCGCAACT
TTCACCCGGGAGACCCGACTCACATCACAGAGGAGATAAAACGCAGCCCCGAATATATCGAGGCCCTTGATGCGCTCGTT
GCCGGACACCGCTCGCTGTTGGCATTCCTGAAGAAGTCCGTTCCCTTTTTCAGCATGCGCTACCAGGGGCATATGAATTG
GGACCTCACGCTGCCAGGGGTTGTCGGGTACTTCTCCGCGATGCTGTACAATCCGAACAACGTTGCCTTCGAGGGCTCCA
CGGCAACGACGCTGCTCGAAATCCTCGTCGGTGACGACTTGTGCCGGATGCTTGGCTATACCATTCCGGACACCGGCGGC
CTGGCTGCCGGTGCCCTCCGACCCTGGGGCCACATTACGTGCGATGGGTCGGTGGCCAACATCGAGGCCATCTGGGCGGC
GCGAAACCTGAAGCTTCTGCCCGTTGCCCTCCAGGCCGCGCTTCGGGAGGACGCATCGATTGCGCTCGGCAGAGACCTCA
CGGTGCCCGTTCCTCAAGGAGGAACAGCGAAGCTCGTGGAGCTCGACACCTGGTCCCTGTTGAACCTTCCAGAAGACACC
GTGCTGGCCCTTTTCGGACGACTGACTCGGGAGTTCCAGATCCCCCGAGATACCCTCACTGAGGTGCTGGCTCGCTTCTC
GCTGCAAAACCTCGGCATGATCGAGTTCTCACGCCGCTTCTTGGGAGACGTTCCCGAGCCTCCAGTATTCCTGGTGCCGG
GCACGCGTCACTATTCGTTCCCGAAGGCCGCGGCGGTGCTGGGGATCGGCGCCTCGAATATGATCGATGTGCCCGTGGAC
CTCGATGCGCGCATGGATCTCACCGCCGTGCGTCGAATCCTGGAGGACTGCCTCACGCGGCGAAGGCCGGTTTACGCCGT
CGTTGCGGTCATTGGCAGTACCGAAGAGAGCGCCATTGATCCATTGAAGGAGCTCCTGGCTTTGCGTGACGAGTACCGAA
GCCGAGGACTCGACTTCCACGTTCATGCGGACGCAGCCTGGGGGGGATATCATGCGTCCTGTATCCGCGAGGATTTCGCA
ATGCTGGAGCCCTTGACGCGTGGCTTCGCCGCCGCTCCACCTCCCGCCATGCCACTGAGCCGGTATGCGACGGAGCAGCT
CCGCGCACTAGAGGGCGCGGACTCCATTACCGTGGACCCACACAAGTCGGGCTACATCCCTTATCCAGCTGGCGCGCTCT
GCTACCGCAACTCGGCCATGCGCGATCTGGTCACCTTCAGCGCCCCCGTGGTCTTTCACGGAGACGCAGAGCCCACAGTT
GGCATCTACGGGCTCGAGGGCTCAAAGCCGGGCGCTGCCGCTGCGGCCGTGTATTTGAGCCACCGGGTCATTCGTCCCAC
CCGAAGTGGATACGGGAAGATCATTGGGCAGGCGCTCTTCAGTTGCAAACGCCTCTATGTGCGTCTGCTCTGCATGGCGA
AGGAAGGGGACCCATTCGTGGTCGTTCCGGTGTCGCGGCTTCCGGCAGAGGCAAACGGTGGAAATATAGTAGAGCAGCTC
CAATTTCTTCGTGAGCGCATTGATCGGGCGACGTCTGCGCAACTGGAGAAGGATCCGGAGGCAATGGCGTTGCTGCGAGA
GCTCGGCCCGGATGAGAATATCCTTGCATACGCGTTCAACTTCCGGACTGCCACGGGGGAGCTCAACCGGGACCTTGCGC
TGGCCAACCAGCTCAACAAGGCAATTTATGATCGGCTTAGCATCGATCCGGGATCGGACATCTATGGCTATGACTTGATC
GTCAGCACGACGGATTTGTCTGGCCCGGGTTACGGTCGTGGCTTCATCGAGAACTACAAGGCCCGGCTCGGAGTAGGTGG
CTCGCCGGGCGACAACATCACGGTGCTGCGTTCGGTGACGATGGACCCCTGGGTTACCGAAACGAAGGAGGGATCCTTTA
TCGACGTGTTGGAGGTTGAGTTCCGCAAGGTGGTGTGTGCGGCTCTTGAGGAACTCATTCCCACTCGAGACAGGGGCTAC
TGA

Upstream 100 bases:

>100_bases
GAGCGGGCGCTCATTCGGTCGCGGTTCTGTAGCAAGGGAGCTGGTCATGAAATCACGACGGGATTTCAGAGGTCCGAGCT
TTGCGAGGCTCCGTGAGGGA

Downstream 100 bases:

>100_bases
GATGGCCGGGCGTCGCTTTCTATTGTACTTTGCATGGAGTCGCGTGCTCGAAGAGAAGGCGTCGCTGGGTACTCTGGAAA
ACCGCTATCCAGCGCTTTTT

Product: group II decarboxylase family protein

Products: NA

Alternate protein names: TDC [H]

Number of amino acids: Translated: 720; Mature: 720

Protein sequence:

>720_residues
MRQVATASNISGLDGAGTRAVEAWFLGPKGENADVLESLIVEAIRDQVFWRRNFHPGDPTHITEEIKRSPEYIEALDALV
AGHRSLLAFLKKSVPFFSMRYQGHMNWDLTLPGVVGYFSAMLYNPNNVAFEGSTATTLLEILVGDDLCRMLGYTIPDTGG
LAAGALRPWGHITCDGSVANIEAIWAARNLKLLPVALQAALREDASIALGRDLTVPVPQGGTAKLVELDTWSLLNLPEDT
VLALFGRLTREFQIPRDTLTEVLARFSLQNLGMIEFSRRFLGDVPEPPVFLVPGTRHYSFPKAAAVLGIGASNMIDVPVD
LDARMDLTAVRRILEDCLTRRRPVYAVVAVIGSTEESAIDPLKELLALRDEYRSRGLDFHVHADAAWGGYHASCIREDFA
MLEPLTRGFAAAPPPAMPLSRYATEQLRALEGADSITVDPHKSGYIPYPAGALCYRNSAMRDLVTFSAPVVFHGDAEPTV
GIYGLEGSKPGAAAAAVYLSHRVIRPTRSGYGKIIGQALFSCKRLYVRLLCMAKEGDPFVVVPVSRLPAEANGGNIVEQL
QFLRERIDRATSAQLEKDPEAMALLRELGPDENILAYAFNFRTATGELNRDLALANQLNKAIYDRLSIDPGSDIYGYDLI
VSTTDLSGPGYGRGFIENYKARLGVGGSPGDNITVLRSVTMDPWVTETKEGSFIDVLEVEFRKVVCAALEELIPTRDRGY

Sequences:

>Translated_720_residues
MRQVATASNISGLDGAGTRAVEAWFLGPKGENADVLESLIVEAIRDQVFWRRNFHPGDPTHITEEIKRSPEYIEALDALV
AGHRSLLAFLKKSVPFFSMRYQGHMNWDLTLPGVVGYFSAMLYNPNNVAFEGSTATTLLEILVGDDLCRMLGYTIPDTGG
LAAGALRPWGHITCDGSVANIEAIWAARNLKLLPVALQAALREDASIALGRDLTVPVPQGGTAKLVELDTWSLLNLPEDT
VLALFGRLTREFQIPRDTLTEVLARFSLQNLGMIEFSRRFLGDVPEPPVFLVPGTRHYSFPKAAAVLGIGASNMIDVPVD
LDARMDLTAVRRILEDCLTRRRPVYAVVAVIGSTEESAIDPLKELLALRDEYRSRGLDFHVHADAAWGGYHASCIREDFA
MLEPLTRGFAAAPPPAMPLSRYATEQLRALEGADSITVDPHKSGYIPYPAGALCYRNSAMRDLVTFSAPVVFHGDAEPTV
GIYGLEGSKPGAAAAAVYLSHRVIRPTRSGYGKIIGQALFSCKRLYVRLLCMAKEGDPFVVVPVSRLPAEANGGNIVEQL
QFLRERIDRATSAQLEKDPEAMALLRELGPDENILAYAFNFRTATGELNRDLALANQLNKAIYDRLSIDPGSDIYGYDLI
VSTTDLSGPGYGRGFIENYKARLGVGGSPGDNITVLRSVTMDPWVTETKEGSFIDVLEVEFRKVVCAALEELIPTRDRGY
>Mature_720_residues
MRQVATASNISGLDGAGTRAVEAWFLGPKGENADVLESLIVEAIRDQVFWRRNFHPGDPTHITEEIKRSPEYIEALDALV
AGHRSLLAFLKKSVPFFSMRYQGHMNWDLTLPGVVGYFSAMLYNPNNVAFEGSTATTLLEILVGDDLCRMLGYTIPDTGG
LAAGALRPWGHITCDGSVANIEAIWAARNLKLLPVALQAALREDASIALGRDLTVPVPQGGTAKLVELDTWSLLNLPEDT
VLALFGRLTREFQIPRDTLTEVLARFSLQNLGMIEFSRRFLGDVPEPPVFLVPGTRHYSFPKAAAVLGIGASNMIDVPVD
LDARMDLTAVRRILEDCLTRRRPVYAVVAVIGSTEESAIDPLKELLALRDEYRSRGLDFHVHADAAWGGYHASCIREDFA
MLEPLTRGFAAAPPPAMPLSRYATEQLRALEGADSITVDPHKSGYIPYPAGALCYRNSAMRDLVTFSAPVVFHGDAEPTV
GIYGLEGSKPGAAAAAVYLSHRVIRPTRSGYGKIIGQALFSCKRLYVRLLCMAKEGDPFVVVPVSRLPAEANGGNIVEQL
QFLRERIDRATSAQLEKDPEAMALLRELGPDENILAYAFNFRTATGELNRDLALANQLNKAIYDRLSIDPGSDIYGYDLI
VSTTDLSGPGYGRGFIENYKARLGVGGSPGDNITVLRSVTMDPWVTETKEGSFIDVLEVEFRKVVCAALEELIPTRDRGY

Specific function: Specifically catalyzes the decarboxylation of L-tyrosine to produce tyramine [H]

COG id: COG0076

COG function: function code E; Glutamate decarboxylase and related PLP-dependent proteins

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the group II decarboxylase family. Archaeal L-tyrosine decarboxylase subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002129
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422
- InterPro:   IPR020931 [H]

Pfam domain/function: PF00282 Pyridoxal_deC [H]

EC number: =4.1.1.25 [H]

Molecular weight: Translated: 78770; Mature: 78770

Theoretical pI: Translated: 5.19; Mature: 5.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRQVATASNISGLDGAGTRAVEAWFLGPKGENADVLESLIVEAIRDQVFWRRNFHPGDPT
CCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCH
HITEEIKRSPEYIEALDALVAGHRSLLAFLKKSVPFFSMRYQGHMNWDLTLPGVVGYFSA
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCEEEECCHHHHHHHH
MLYNPNNVAFEGSTATTLLEILVGDDLCRMLGYTIPDTGGLAAGALRPWGHITCDGSVAN
HEECCCCEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEECCCCCC
IEAIWAARNLKLLPVALQAALREDASIALGRDLTVPVPQGGTAKLVELDTWSLLNLPEDT
EEEEEEECCCEEHHHHHHHHHHCCCCEEECCCCEEECCCCCCEEEEEECCCCCCCCCHHH
VLALFGRLTREFQIPRDTLTEVLARFSLQNLGMIEFSRRFLGDVPEPPVFLVPGTRHYSF
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCEEEECCCCCCCC
PKAAAVLGIGASNMIDVPVDLDARMDLTAVRRILEDCLTRRRPVYAVVAVIGSTEESAID
CHHHHEEECCCCCEEECCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHH
PLKELLALRDEYRSRGLDFHVHADAAWGGYHASCIREDFAMLEPLTRGFAAAPPPAMPLS
HHHHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHH
RYATEQLRALEGADSITVDPHKSGYIPYPAGALCYRNSAMRDLVTFSAPVVFHGDAEPTV
HHHHHHHHHHCCCCCEEECCCCCCCCCCCCCHHHHCCHHHHHHHHHCCCEEEECCCCCCE
GIYGLEGSKPGAAAAAVYLSHRVIRPTRSGYGKIIGQALFSCKRLYVRLLCMAKEGDPFV
EEEECCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEE
VVPVSRLPAEANGGNIVEQLQFLRERIDRATSAQLEKDPEAMALLRELGPDENILAYAFN
EEEHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCEEEEEEE
FRTATGELNRDLALANQLNKAIYDRLSIDPGSDIYGYDLIVSTTDLSGPGYGRGFIENYK
EEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEEECCCCCCCCCCHHHHHHH
ARLGVGGSPGDNITVLRSVTMDPWVTETKEGSFIDVLEVEFRKVVCAALEELIPTRDRGY
HHCCCCCCCCCCEEEEEEECCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MRQVATASNISGLDGAGTRAVEAWFLGPKGENADVLESLIVEAIRDQVFWRRNFHPGDPT
CCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCH
HITEEIKRSPEYIEALDALVAGHRSLLAFLKKSVPFFSMRYQGHMNWDLTLPGVVGYFSA
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCEEEECCHHHHHHHH
MLYNPNNVAFEGSTATTLLEILVGDDLCRMLGYTIPDTGGLAAGALRPWGHITCDGSVAN
HEECCCCEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEECCCCCC
IEAIWAARNLKLLPVALQAALREDASIALGRDLTVPVPQGGTAKLVELDTWSLLNLPEDT
EEEEEEECCCEEHHHHHHHHHHCCCCEEECCCCEEECCCCCCEEEEEECCCCCCCCCHHH
VLALFGRLTREFQIPRDTLTEVLARFSLQNLGMIEFSRRFLGDVPEPPVFLVPGTRHYSF
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCEEEECCCCCCCC
PKAAAVLGIGASNMIDVPVDLDARMDLTAVRRILEDCLTRRRPVYAVVAVIGSTEESAID
CHHHHEEECCCCCEEECCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHH
PLKELLALRDEYRSRGLDFHVHADAAWGGYHASCIREDFAMLEPLTRGFAAAPPPAMPLS
HHHHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHH
RYATEQLRALEGADSITVDPHKSGYIPYPAGALCYRNSAMRDLVTFSAPVVFHGDAEPTV
HHHHHHHHHHCCCCCEEECCCCCCCCCCCCCHHHHCCHHHHHHHHHCCCEEEECCCCCCE
GIYGLEGSKPGAAAAAVYLSHRVIRPTRSGYGKIIGQALFSCKRLYVRLLCMAKEGDPFV
EEEECCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEE
VVPVSRLPAEANGGNIVEQLQFLRERIDRATSAQLEKDPEAMALLRELGPDENILAYAFN
EEEHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCEEEEEEE
FRTATGELNRDLALANQLNKAIYDRLSIDPGSDIYGYDLIVSTTDLSGPGYGRGFIENYK
EEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEEECCCCCCCCCCHHHHHHH
ARLGVGGSPGDNITVLRSVTMDPWVTETKEGSFIDVLEVEFRKVVCAALEELIPTRDRGY
HHCCCCCCCCCCEEEEEEECCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9371463 [H]