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The map label for this gene is purC [H]

Identifier: 108761229

GI number: 108761229

Start: 2414366

End: 2415325

Strand: Reverse

Name: purC [H]

Synonym: MXAN_2080

Alternate gene names: 108761229

Gene position: 2415325-2414366 (Counterclockwise)

Preceding gene: 108763831

Following gene: 108763973

Centisome position: 26.43

GC content: 67.19

Gene sequence:

>960_bases
GTGAATACCTCCGCACTTCACGCGCAGCTTCCCCTCACCCTCCAGCAGACGGACCTGCCCGCGCTCGGCCAGCACTACCG
CGGCAAGGTTCGCGAGACGTACCGACAGGATGACCAGCTCATCCTGGTGACGACGGACCGGCTGTCCGCGTTCGACCACA
TCCTCACCACCATCCCCTTCAAGGGCGAGGTGCTCAACCGGCTGTCCGCATTCTGGTTCGAGCGCACGAAGCACATCGTC
CCCAATCACGTGCTGGACGTGCCCGACGCCAACGTCACCGTGGCGCGTGCCTGTCAGCCCTTCGCCGTGGAAGTAGTGGT
GCGCGGCTACCTCACCGGCAGCCTGTGGCGCGACTACCAGAAGGGCACGCACACCGCCTACGGACTGCCCTTCCCGGACG
GCCTGCGCAAGGACGAGGCCTTCCCCGCCCCCCTCATCACCCCGTCCACCAAGGCGGAGTACGGCCTGCACGACGAGCCC
ATCTCGGAGAAGGAGCTTCTGGCGCGGGGCCTGGCCACGCCTGGTGACTGGGCGCGCATCTCCGAGGCCGCGCTGGGCCT
CTTCGCGGAGGGCCAGAAGTGGGCGCGCTCACGCGGCCTCATCCTCGTGGATACCAAGTACGAGTTCGGCAAGGTGGGCG
ACACGCTCTACGTCATCGACGAGATGCACACCCCGGACTCCAGCCGCTACTGGATGGCCGACGAGTACGAGGCGCGCTTC
GCGAAGGGCGAGGACCAGCGCATGCTGGACAAGGAGAACATCCGCCAGTGGCTCATCCGCGAGCGGAACTTCTCTGGCCA
GGGCACGCCGCCGCCCATCCCTGACGACGTGCGCGTGGACCTGGCCGCGAAGTACGTGGCGGCCTACGAGCACATCACCG
GCACCACGCTGACGCTGGAGCCGGGCGACGTGAAGACCCGCATCGAGCGCAACCTGCGTGAGAAGGGCTACCTGAAGTAG

Upstream 100 bases:

>100_bases
CTTCTTCCCTGCCCGCTTCGCTCCAGTAGAGTCGCGCGCCTCAAGTCAGGCCCCGTTTCCTCTCGCCCTTCCCGCGAGAG
AGAGGGGCCGCGAGGCGACA

Downstream 100 bases:

>100_bases
CCCTCCTCCATCATCGGCACAGGGTGCCTACGCGCTCCGGCCGAACACGCGCTGGAAGACGTCGTCCATGTGGCGCGTGT
GGTAGCCCGAGGAGAAGCAG

Product: phosphoribosylaminoimidazole-succinocarboxamide synthase

Products: NA

Alternate protein names: SAICAR synthetase [H]

Number of amino acids: Translated: 319; Mature: 319

Protein sequence:

>319_residues
MNTSALHAQLPLTLQQTDLPALGQHYRGKVRETYRQDDQLILVTTDRLSAFDHILTTIPFKGEVLNRLSAFWFERTKHIV
PNHVLDVPDANVTVARACQPFAVEVVVRGYLTGSLWRDYQKGTHTAYGLPFPDGLRKDEAFPAPLITPSTKAEYGLHDEP
ISEKELLARGLATPGDWARISEAALGLFAEGQKWARSRGLILVDTKYEFGKVGDTLYVIDEMHTPDSSRYWMADEYEARF
AKGEDQRMLDKENIRQWLIRERNFSGQGTPPPIPDDVRVDLAAKYVAAYEHITGTTLTLEPGDVKTRIERNLREKGYLK

Sequences:

>Translated_319_residues
MNTSALHAQLPLTLQQTDLPALGQHYRGKVRETYRQDDQLILVTTDRLSAFDHILTTIPFKGEVLNRLSAFWFERTKHIV
PNHVLDVPDANVTVARACQPFAVEVVVRGYLTGSLWRDYQKGTHTAYGLPFPDGLRKDEAFPAPLITPSTKAEYGLHDEP
ISEKELLARGLATPGDWARISEAALGLFAEGQKWARSRGLILVDTKYEFGKVGDTLYVIDEMHTPDSSRYWMADEYEARF
AKGEDQRMLDKENIRQWLIRERNFSGQGTPPPIPDDVRVDLAAKYVAAYEHITGTTLTLEPGDVKTRIERNLREKGYLK
>Mature_319_residues
MNTSALHAQLPLTLQQTDLPALGQHYRGKVRETYRQDDQLILVTTDRLSAFDHILTTIPFKGEVLNRLSAFWFERTKHIV
PNHVLDVPDANVTVARACQPFAVEVVVRGYLTGSLWRDYQKGTHTAYGLPFPDGLRKDEAFPAPLITPSTKAEYGLHDEP
ISEKELLARGLATPGDWARISEAALGLFAEGQKWARSRGLILVDTKYEFGKVGDTLYVIDEMHTPDSSRYWMADEYEARF
AKGEDQRMLDKENIRQWLIRERNFSGQGTPPPIPDDVRVDLAAKYVAAYEHITGTTLTLEPGDVKTRIERNLREKGYLK

Specific function: De novo purine biosynthesis; seventh step. [C]

COG id: COG0152

COG function: function code F; Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the SAICAR synthetase family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6319326, Length=300, Percent_Identity=38, Blast_Score=182, Evalue=5e-47,

Paralogues:

None

Copy number: 1680 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 13,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013816
- InterPro:   IPR001636
- InterPro:   IPR018236 [H]

Pfam domain/function: PF01259 SAICAR_synt [H]

EC number: =6.3.2.6 [H]

Molecular weight: Translated: 36181; Mature: 36181

Theoretical pI: Translated: 6.43; Mature: 6.43

Prosite motif: PS01058 SAICAR_SYNTHETASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTSALHAQLPLTLQQTDLPALGQHYRGKVRETYRQDDQLILVTTDRLSAFDHILTTIPF
CCCCCEEEECCEEEECCCCCHHHHHHHHHHHHHHCCCCCEEEEECHHHHHHHHHHHCCCC
KGEVLNRLSAFWFERTKHIVPNHVLDVPDANVTVARACQPFAVEVVVRGYLTGSLWRDYQ
CHHHHHHHHHHHHHHHHHCCCCCEECCCCCCEEHHHCCCCHHHHHHHHHHHHHHHHHHHH
KGTHTAYGLPFPDGLRKDEAFPAPLITPSTKAEYGLHDEPISEKELLARGLATPGDWARI
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCHHHH
SEAALGLFAEGQKWARSRGLILVDTKYEFGKVGDTLYVIDEMHTPDSSRYWMADEYEARF
HHHHHHHHHCCHHHHHHCCEEEEECCCCCCCCCCEEEEEECCCCCCCCCEEECCHHHHHH
AKGEDQRMLDKENIRQWLIRERNFSGQGTPPPIPDDVRVDLAAKYVAAYEHITGTTLTLE
CCCCCHHHHCHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEC
PGDVKTRIERNLREKGYLK
CCCHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MNTSALHAQLPLTLQQTDLPALGQHYRGKVRETYRQDDQLILVTTDRLSAFDHILTTIPF
CCCCCEEEECCEEEECCCCCHHHHHHHHHHHHHHCCCCCEEEEECHHHHHHHHHHHCCCC
KGEVLNRLSAFWFERTKHIVPNHVLDVPDANVTVARACQPFAVEVVVRGYLTGSLWRDYQ
CHHHHHHHHHHHHHHHHHCCCCCEECCCCCCEEHHHCCCCHHHHHHHHHHHHHHHHHHHH
KGTHTAYGLPFPDGLRKDEAFPAPLITPSTKAEYGLHDEPISEKELLARGLATPGDWARI
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCHHHH
SEAALGLFAEGQKWARSRGLILVDTKYEFGKVGDTLYVIDEMHTPDSSRYWMADEYEARF
HHHHHHHHHCCHHHHHHCCEEEEECCCCCCCCCCEEEEEECCCCCCCCCEEECCHHHHHH
AKGEDQRMLDKENIRQWLIRERNFSGQGTPPPIPDDVRVDLAAKYVAAYEHITGTTLTLE
CCCCCHHHHCHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEC
PGDVKTRIERNLREKGYLK
CCCHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA