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The map label for this gene is estB [H]

Identifier: 108761197

GI number: 108761197

Start: 2485310

End: 2487415

Strand: Direct

Name: estB [H]

Synonym: MXAN_2150

Alternate gene names: 108761197

Gene position: 2485310-2487415 (Clockwise)

Preceding gene: 108758108

Following gene: 108764030

Centisome position: 27.19

GC content: 65.24

Gene sequence:

>2106_bases
TTGCTGGCCGCGGCTGAGGGGAAATGCGCGCTGGAGTCGTTTCCTGTTGGCGGTACCAACGTCAAGCAGGAGTTCTCGAG
CATGAAACCTTTCAGCATGAGGCCGCTACTGGCGGTCCTGTCAGTGCTGGTCGTATCCCTCGTGGGATGCGGGGTGCCAG
AGGAAGAGTCCCGCGACTCTTCCAGCGCCGAGTCCCAGGCACTGGCCGGTCCATATGATGCCTGGGTTGCCCGCCACGGG
CTCACCAACGCCCAATATCAGACGGAGTTCAATACGTGGGTGGGGCAAGGCTATCGTCTCTCCTATGTCAGCGGTTACGA
AGAGGGGGGCAGTGCCCGTTACGCGGCCATCTGGGAGCAGACGAGCGGCCCCGCCTGGCGCGCCTTCCACGGGCTGACTT
CCGCGCAGTATCAGACCACCGTCGTCAATCAAGACGCGCAGGGATACCGCCCGGTGGTGGTCAACGGGTACAGCGTCGGA
GGCGTCGCCTACTTCGCGGTCATCTTCCACGTGGACAGTGGTGCCGCGTGGGTGGCCCGCCATGACCTGAGCGCGTCCCA
GTACCAGACGGAGTTCAACACCTGGGCGGGGCAGGGCTACCGGCTCGTGCACGTGAGTGGCTACACGTCCGGTGGCGCGG
AGCGCTACGCGGCCATCTGGGAGCAGACGAGCGGCCCGGCCTGGCGGGCCTACCACGGGCTGACCGCGGCCCAGTACCAG
TCCACGTTCAATACCAACGCGGCCCAGGGTTACCAGCTCGCGAAGGTCAGCAGCTACAACGTGGGCGGCACGGACCGGTA
CGCGGCCATCTTCCAGGTTTCATCGGGGATTCCGACCGCCGCGCGTCATGGGCTCTCCTCCGCCGCGTATCAACAGGCCG
TGACGGACCTCAAGAACCAGGGGTATCGCCCCGTCCTGGTGGCGGCGCACAACAATGGGAGCCAGCCCGAGTTCGCCCTG
ATTTGGCAGAACCTGACGTTCAGCGCGGCCGACCTGCAGCACATTGACGACACCGTCCAGCAGGCGATGACCAGCACGAA
CACCGTCGGACTGTCGCTGGCCATCACCCGCCACGGGCGCCTCGTGTTCGCCAAGGGGTATGGACTGGCCGACCGAACCA
GCAACACGCCGGTCAACACCTCCCACCGCTTCCGCGTCGCCAGTGTGTCCAAGCCGATGACATCCATTGGCATCATGCGG
CTGATTGAAAGCGGCCAGATCCGTCTGACGGACCGCGTCTTCGGCAGGGGCGGATTGCTTGGTGAGACGTTCGGCGCGCA
GGGCACCTACGCGGACAGCCGCGTCCTGAACATCACGGTCCAGCACCTGCTCGAGCACACCGCGGGCGCATGGGACAACG
ACGGCGCAGACGGCACGGGCGACCCCATGTTCATGAACACGGGCATGACGCACGCCCAGCTCATCCAATGGGTGTTGCAG
AACGTGCCGCTCGAGTTCGCGCCTGGGACGACGTACCAGTATTCGAACTTCGGCTACAGCGTCCTTGGCCGCATCATCGA
GCGGGTCACGGGCATGACCTATGACGCCTATATGCGCGCCAACGTGTTCACGCCCAGCGGCGCCACCAGCTTCGCAGTGG
GGGGCGATACGTTGAGCGCGCGTCTGCCGAACGAGCCCGTCTACTACCAGCTTGGCACTGGAGCCTTCAGCCCGTACGGC
ATGCCGGTGCGTCGCATGGATGCGCACGGCGGCTGGGTCGTCACGCCCATCGATTTGCTGCGCGTCGCCGTGCGCGCGGA
TGGGTTCTCCACCGTCCCGGATCTGCTGAGCGCGAGCTCTCTCACCACGATGACCACACGCACGACGGCGCTCGACACCT
TGGGCAACTCCGTCAACTACGCCAAGGGCTGGTCGGTGAACAGCCTTCCCAACTGGTGGCACGGTGGCTACATCCCGGGC
ACCCGGGCCCTGTTGGTGCGCACCGATGACCGCTATGGGCCCAGCCGCTCCGAGGAGTTCACCTGGTCCGTCATGACCAA
CTCCAACAACAGCTCCGGTTCGGGCACGCCCGACATCAACCTCGACAGCCTCATGTGGAACGTCGTGAATGGCGTCAGCG
CCTGGCCCGCGCACGACCTGTTCTAA

Upstream 100 bases:

>100_bases
ACGCTTCGCTTGAAGGCCTTACCGAAGGGACTTTCCGCGATGTGGGCCAGCCTGCTGACATGCATGTGGATTTGGCGCCA
CGCGCGAGGGGGCTCTCATT

Downstream 100 bases:

>100_bases
TCAGGGGCTCCGCCGGACTTTCCGGGAGGGCTCGTAGGACCGGCGAGGCTCGCAAGGGCCTCTGCCGGTCCGTGATGCAT
CTCACTGTACCACCAGCACG

Product: beta-lactamase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 701; Mature: 701

Protein sequence:

>701_residues
MLAAAEGKCALESFPVGGTNVKQEFSSMKPFSMRPLLAVLSVLVVSLVGCGVPEEESRDSSSAESQALAGPYDAWVARHG
LTNAQYQTEFNTWVGQGYRLSYVSGYEEGGSARYAAIWEQTSGPAWRAFHGLTSAQYQTTVVNQDAQGYRPVVVNGYSVG
GVAYFAVIFHVDSGAAWVARHDLSASQYQTEFNTWAGQGYRLVHVSGYTSGGAERYAAIWEQTSGPAWRAYHGLTAAQYQ
STFNTNAAQGYQLAKVSSYNVGGTDRYAAIFQVSSGIPTAARHGLSSAAYQQAVTDLKNQGYRPVLVAAHNNGSQPEFAL
IWQNLTFSAADLQHIDDTVQQAMTSTNTVGLSLAITRHGRLVFAKGYGLADRTSNTPVNTSHRFRVASVSKPMTSIGIMR
LIESGQIRLTDRVFGRGGLLGETFGAQGTYADSRVLNITVQHLLEHTAGAWDNDGADGTGDPMFMNTGMTHAQLIQWVLQ
NVPLEFAPGTTYQYSNFGYSVLGRIIERVTGMTYDAYMRANVFTPSGATSFAVGGDTLSARLPNEPVYYQLGTGAFSPYG
MPVRRMDAHGGWVVTPIDLLRVAVRADGFSTVPDLLSASSLTTMTTRTTALDTLGNSVNYAKGWSVNSLPNWWHGGYIPG
TRALLVRTDDRYGPSRSEEFTWSVMTNSNNSSGSGTPDINLDSLMWNVVNGVSAWPAHDLF

Sequences:

>Translated_701_residues
MLAAAEGKCALESFPVGGTNVKQEFSSMKPFSMRPLLAVLSVLVVSLVGCGVPEEESRDSSSAESQALAGPYDAWVARHG
LTNAQYQTEFNTWVGQGYRLSYVSGYEEGGSARYAAIWEQTSGPAWRAFHGLTSAQYQTTVVNQDAQGYRPVVVNGYSVG
GVAYFAVIFHVDSGAAWVARHDLSASQYQTEFNTWAGQGYRLVHVSGYTSGGAERYAAIWEQTSGPAWRAYHGLTAAQYQ
STFNTNAAQGYQLAKVSSYNVGGTDRYAAIFQVSSGIPTAARHGLSSAAYQQAVTDLKNQGYRPVLVAAHNNGSQPEFAL
IWQNLTFSAADLQHIDDTVQQAMTSTNTVGLSLAITRHGRLVFAKGYGLADRTSNTPVNTSHRFRVASVSKPMTSIGIMR
LIESGQIRLTDRVFGRGGLLGETFGAQGTYADSRVLNITVQHLLEHTAGAWDNDGADGTGDPMFMNTGMTHAQLIQWVLQ
NVPLEFAPGTTYQYSNFGYSVLGRIIERVTGMTYDAYMRANVFTPSGATSFAVGGDTLSARLPNEPVYYQLGTGAFSPYG
MPVRRMDAHGGWVVTPIDLLRVAVRADGFSTVPDLLSASSLTTMTTRTTALDTLGNSVNYAKGWSVNSLPNWWHGGYIPG
TRALLVRTDDRYGPSRSEEFTWSVMTNSNNSSGSGTPDINLDSLMWNVVNGVSAWPAHDLF
>Mature_701_residues
MLAAAEGKCALESFPVGGTNVKQEFSSMKPFSMRPLLAVLSVLVVSLVGCGVPEEESRDSSSAESQALAGPYDAWVARHG
LTNAQYQTEFNTWVGQGYRLSYVSGYEEGGSARYAAIWEQTSGPAWRAFHGLTSAQYQTTVVNQDAQGYRPVVVNGYSVG
GVAYFAVIFHVDSGAAWVARHDLSASQYQTEFNTWAGQGYRLVHVSGYTSGGAERYAAIWEQTSGPAWRAYHGLTAAQYQ
STFNTNAAQGYQLAKVSSYNVGGTDRYAAIFQVSSGIPTAARHGLSSAAYQQAVTDLKNQGYRPVLVAAHNNGSQPEFAL
IWQNLTFSAADLQHIDDTVQQAMTSTNTVGLSLAITRHGRLVFAKGYGLADRTSNTPVNTSHRFRVASVSKPMTSIGIMR
LIESGQIRLTDRVFGRGGLLGETFGAQGTYADSRVLNITVQHLLEHTAGAWDNDGADGTGDPMFMNTGMTHAQLIQWVLQ
NVPLEFAPGTTYQYSNFGYSVLGRIIERVTGMTYDAYMRANVFTPSGATSFAVGGDTLSARLPNEPVYYQLGTGAFSPYG
MPVRRMDAHGGWVVTPIDLLRVAVRADGFSTVPDLLSASSLTTMTTRTTALDTLGNSVNYAKGWSVNSLPNWWHGGYIPG
TRALLVRTDDRYGPSRSEEFTWSVMTNSNNSSGSGTPDINLDSLMWNVVNGVSAWPAHDLF

Specific function: Acts on short-chain (C4-C6) fatty acid esters and triglycerides, including tertiary alcohol esters. Activity on p- nitrophenyl esters is generally higher than on o-nitrophenyl esters. Lacks beta-lactamase activity; it hydrolyzes the ester bond of cephalos

COG id: COG1680

COG function: function code V; Beta-lactamase class C and other penicillin binding proteins

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-A beta-lactamase family [H]

Homologues:

Organism=Caenorhabditis elegans, GI17550934, Length=323, Percent_Identity=41.4860681114551, Blast_Score=249, Evalue=4e-66,
Organism=Caenorhabditis elegans, GI17565630, Length=388, Percent_Identity=27.0618556701031, Blast_Score=128, Evalue=1e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR001466
- InterPro:   IPR000871 [H]

Pfam domain/function: PF00144 Beta-lactamase [H]

EC number: NA

Molecular weight: Translated: 75817; Mature: 75817

Theoretical pI: Translated: 6.66; Mature: 6.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLAAAEGKCALESFPVGGTNVKQEFSSMKPFSMRPLLAVLSVLVVSLVGCGVPEEESRDS
CCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCC
SSAESQALAGPYDAWVARHGLTNAQYQTEFNTWVGQGYRLSYVSGYEEGGSARYAAIWEQ
CCHHHHHCCCCHHHHHHHCCCCCCEEEEEHHHHHCCCEEEEEECCCCCCCCEEEEEEEEC
TSGPAWRAFHGLTSAQYQTTVVNQDAQGYRPVVVNGYSVGGVAYFAVIFHVDSGAAWVAR
CCCCHHHHHHCCCCCCEEEEEECCCCCCCCCEEEECCCCCHHEEEEEEEEECCCCEEEEE
HDLSASQYQTEFNTWAGQGYRLVHVSGYTSGGAERYAAIWEQTSGPAWRAYHGLTAAQYQ
CCCCHHHHHHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHHCCCCCCCHHHHCCCHHHHH
STFNTNAAQGYQLAKVSSYNVGGTDRYAAIFQVSSGIPTAARHGLSSAAYQQAVTDLKNQ
HHCCCCCCCCEEEEEEECCCCCCCCCEEEEEEECCCCCHHHHHCCHHHHHHHHHHHHHHC
GYRPVLVAAHNNGSQPEFALIWQNLTFSAADLQHIDDTVQQAMTSTNTVGLSLAITRHGR
CCCEEEEEECCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCEEEEEEEEECCC
LVFAKGYGLADRTSNTPVNTSHRFRVASVSKPMTSIGIMRLIESGQIRLTDRVFGRGGLL
EEEEECCCCCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHCCCCEEEEEEECCCCCCC
GETFGAQGTYADSRVLNITVQHLLEHTAGAWDNDGADGTGDPMFMNTGMTHAQLIQWVLQ
CCCCCCCCCCCCCEEEHHHHHHHHHHHCCCCCCCCCCCCCCCEEEECCCCHHHHHHHHHH
NVPLEFAPGTTYQYSNFGYSVLGRIIERVTGMTYDAYMRANVFTPSGATSFAVGGDTLSA
HCCEEECCCCCEEECCCCHHHHHHHHHHHHCCEEEHEEEEEEECCCCCCEEEECCCEEEE
RLPNEPVYYQLGTGAFSPYGMPVRRMDAHGGWVVTPIDLLRVAVRADGFSTVPDLLSASS
ECCCCCEEEEECCCCCCCCCCCCEEECCCCCEEEEHHHHHHHHHHCCCCCHHHHHHCCCC
LTTMTTRTTALDTLGNSVNYAKGWSVNSLPNWWHGGYIPGTRALLVRTDDRYGPSRSEEF
CEEEEEHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCE
TWSVMTNSNNSSGSGTPDINLDSLMWNVVNGVSAWPAHDLF
EEEEEECCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MLAAAEGKCALESFPVGGTNVKQEFSSMKPFSMRPLLAVLSVLVVSLVGCGVPEEESRDS
CCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCC
SSAESQALAGPYDAWVARHGLTNAQYQTEFNTWVGQGYRLSYVSGYEEGGSARYAAIWEQ
CCHHHHHCCCCHHHHHHHCCCCCCEEEEEHHHHHCCCEEEEEECCCCCCCCEEEEEEEEC
TSGPAWRAFHGLTSAQYQTTVVNQDAQGYRPVVVNGYSVGGVAYFAVIFHVDSGAAWVAR
CCCCHHHHHHCCCCCCEEEEEECCCCCCCCCEEEECCCCCHHEEEEEEEEECCCCEEEEE
HDLSASQYQTEFNTWAGQGYRLVHVSGYTSGGAERYAAIWEQTSGPAWRAYHGLTAAQYQ
CCCCHHHHHHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHHCCCCCCCHHHHCCCHHHHH
STFNTNAAQGYQLAKVSSYNVGGTDRYAAIFQVSSGIPTAARHGLSSAAYQQAVTDLKNQ
HHCCCCCCCCEEEEEEECCCCCCCCCEEEEEEECCCCCHHHHHCCHHHHHHHHHHHHHHC
GYRPVLVAAHNNGSQPEFALIWQNLTFSAADLQHIDDTVQQAMTSTNTVGLSLAITRHGR
CCCEEEEEECCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCEEEEEEEEECCC
LVFAKGYGLADRTSNTPVNTSHRFRVASVSKPMTSIGIMRLIESGQIRLTDRVFGRGGLL
EEEEECCCCCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHCCCCEEEEEEECCCCCCC
GETFGAQGTYADSRVLNITVQHLLEHTAGAWDNDGADGTGDPMFMNTGMTHAQLIQWVLQ
CCCCCCCCCCCCCEEEHHHHHHHHHHHCCCCCCCCCCCCCCCEEEECCCCHHHHHHHHHH
NVPLEFAPGTTYQYSNFGYSVLGRIIERVTGMTYDAYMRANVFTPSGATSFAVGGDTLSA
HCCEEECCCCCEEECCCCHHHHHHHHHHHHCCEEEHEEEEEEECCCCCCEEEECCCEEEE
RLPNEPVYYQLGTGAFSPYGMPVRRMDAHGGWVVTPIDLLRVAVRADGFSTVPDLLSASS
ECCCCCEEEEECCCCCCCCCCCCEEECCCCCEEEEHHHHHHHHHHCCCCCHHHHHHCCCC
LTTMTTRTTALDTLGNSVNYAKGWSVNSLPNWWHGGYIPGTRALLVRTDDRYGPSRSEEF
CEEEEEHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCE
TWSVMTNSNNSSGSGTPDINLDSLMWNVVNGVSAWPAHDLF
EEEEEECCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11472796; 11847270 [H]