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The map label for this gene is hipA [C]

Identifier: 108761177

GI number: 108761177

Start: 111354

End: 112583

Strand: Reverse

Name: hipA [C]

Synonym: MXAN_0097

Alternate gene names: 108761177

Gene position: 112583-111354 (Counterclockwise)

Preceding gene: 108762017

Following gene: 108758711

Centisome position: 1.23

GC content: 68.29

Gene sequence:

>1230_bases
TTGGAGCCCACCCGCACCACGGCCGGAATCCTCGACGTCCACCTGGGCGACGTCCACGTCGGCACGCTGACGCTGCTGGA
GGACGAACGCATCGAGTTCGTCATCGCGGAGGAGTACCGCCAGCGCTACCCACGCCCGGTGCTGGGACAGATTTTCGAGG
ACGACCTCTCGCGCCGGCACGTCAGCCGCCTGCGCCTGCCTTCGTACTTCTCCAACCTGCTCCCGGAAGGCTCGCTGCGC
GAGCTCATCGCCGAACGCGAGCAGGTGGCCCGCCAGCGCGAGTTCTTCCTCATCGCGCGGCTGGGTGAGGACCTGCCCGG
CGCCATCGTCGTGCGGCCCGCCAGCGTGCTGTCACTCAGCGGAATGGAGCCGCTGGAGGAGCCCCAGCCGCCCCACGCGC
CGCAGGAGCAGGAGCCGCTGCGCTTCTCACTGGCGGGCGTGCAGCTCAAGTTCTCCATGCTGCGCCGGGACAAGGCGATG
ACGCTCCCGGCGGGTGGACGCGGCGGCAACTGGATTGTGAAGCTGCCGGACAACCGCTACGACCGCGTCCCGGAGAACGA
GTTCTCCATGATGACGTGGGCCCGCGCCGCCGGCATCACCGTCCCCGAAGTGGCGCTGCTGGACGTGGCCGACATCCAGG
GCCTGCCCGAAGGCATCACCCTGCGCGAGAACGTGGCCTACGCCGTGCGCCGCTTCGACCGCCCCGAGCCCGGCCGCCGG
GTCCACATGGAGGACCTGACGCAGGTGCTGGGGCTGTACGCGGATGAGAAGTACAAGAAGTACAACTACGAGACGGTCGC
CAACGTCATCTACAAGGTCGCCGGACTGGACGCGCTGCACGAGTTCCTGCGGCGGCTGGTGTTCATCACCGTCATTGGCA
ACGGGGACGCGCACCACAAGAACTGGTCCCTGCTCTACCCGGACGGCACCCGCGCCACGCTGTCACCCGCGTACGACTTG
GTGTCCACGCTCCAGTACATGCCGGCGGACACGCTCGCGCTCAACTTCGCGAAGTCAAAGCGCTTCGAGGACATCTCCCT
GGGCAGCTTCGAACGGCTGGCGCGCAAGCTGGCGCTGCCCCCCAGCGACGTGCTGCCGGTGGTGAAGTCCGCGGTGGAAG
CGTCGCTCGACACCTGGTCCTCGCTTCACGCGCAACTGCCCCTGCCGGATGAGAGCCGCCGCCGCATCGAAGCCCACTGG
AAGCGCGTGCCCCTGCTCCAGGGGCAATGA

Upstream 100 bases:

>100_bases
ATCGATAGACACATCATCGAGTTCCTGCGGGCCCGCACCCGCTACGAGGAGTCGGACCGTCCGTCCCTCCAATCGCTGGT
CGTCGAGGAGGAGGACTGAC

Downstream 100 bases:

>100_bases
ACCGGGGCCCGCCATGAGCGAAGACGCCTTCTTCACCGTCTATGGCAACCTGCCCCGTCACGGCCCTGGCAGCGACGACT
GCACCCGGGAGGCCCTGCGA

Product: HipA-like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 409; Mature: 409

Protein sequence:

>409_residues
MEPTRTTAGILDVHLGDVHVGTLTLLEDERIEFVIAEEYRQRYPRPVLGQIFEDDLSRRHVSRLRLPSYFSNLLPEGSLR
ELIAEREQVARQREFFLIARLGEDLPGAIVVRPASVLSLSGMEPLEEPQPPHAPQEQEPLRFSLAGVQLKFSMLRRDKAM
TLPAGGRGGNWIVKLPDNRYDRVPENEFSMMTWARAAGITVPEVALLDVADIQGLPEGITLRENVAYAVRRFDRPEPGRR
VHMEDLTQVLGLYADEKYKKYNYETVANVIYKVAGLDALHEFLRRLVFITVIGNGDAHHKNWSLLYPDGTRATLSPAYDL
VSTLQYMPADTLALNFAKSKRFEDISLGSFERLARKLALPPSDVLPVVKSAVEASLDTWSSLHAQLPLPDESRRRIEAHW
KRVPLLQGQ

Sequences:

>Translated_409_residues
MEPTRTTAGILDVHLGDVHVGTLTLLEDERIEFVIAEEYRQRYPRPVLGQIFEDDLSRRHVSRLRLPSYFSNLLPEGSLR
ELIAEREQVARQREFFLIARLGEDLPGAIVVRPASVLSLSGMEPLEEPQPPHAPQEQEPLRFSLAGVQLKFSMLRRDKAM
TLPAGGRGGNWIVKLPDNRYDRVPENEFSMMTWARAAGITVPEVALLDVADIQGLPEGITLRENVAYAVRRFDRPEPGRR
VHMEDLTQVLGLYADEKYKKYNYETVANVIYKVAGLDALHEFLRRLVFITVIGNGDAHHKNWSLLYPDGTRATLSPAYDL
VSTLQYMPADTLALNFAKSKRFEDISLGSFERLARKLALPPSDVLPVVKSAVEASLDTWSSLHAQLPLPDESRRRIEAHW
KRVPLLQGQ
>Mature_409_residues
MEPTRTTAGILDVHLGDVHVGTLTLLEDERIEFVIAEEYRQRYPRPVLGQIFEDDLSRRHVSRLRLPSYFSNLLPEGSLR
ELIAEREQVARQREFFLIARLGEDLPGAIVVRPASVLSLSGMEPLEEPQPPHAPQEQEPLRFSLAGVQLKFSMLRRDKAM
TLPAGGRGGNWIVKLPDNRYDRVPENEFSMMTWARAAGITVPEVALLDVADIQGLPEGITLRENVAYAVRRFDRPEPGRR
VHMEDLTQVLGLYADEKYKKYNYETVANVIYKVAGLDALHEFLRRLVFITVIGNGDAHHKNWSLLYPDGTRATLSPAYDL
VSTLQYMPADTLALNFAKSKRFEDISLGSFERLARKLALPPSDVLPVVKSAVEASLDTWSSLHAQLPLPDESRRRIEAHW
KRVPLLQGQ

Specific function: Unbalanced Or Excessive Expression Of Hipa Is Toxic To The Cell. [C]

COG id: COG3550

COG function: function code R; Uncharacterized protein related to capsule biosynthesis enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: To E.coli hipA, H.influenzae HI_0665 and y4mE [H]

Homologues:

Organism=Escherichia coli, GI1787785, Length=372, Percent_Identity=25.2688172043011, Blast_Score=96, Evalue=4e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012893
- InterPro:   IPR012894
- InterPro:   IPR017508 [H]

Pfam domain/function: PF07804 HipA_C; PF07805 HipA_N [H]

EC number: NA

Molecular weight: Translated: 46315; Mature: 46315

Theoretical pI: Translated: 6.53; Mature: 6.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEPTRTTAGILDVHLGDVHVGTLTLLEDERIEFVIAEEYRQRYPRPVLGQIFEDDLSRRH
CCCCCCCCCEEEEEECCEEEEEEEEEECCCEEEEEEHHHHHHCCCCHHHHHHHHHHHHHH
VSRLRLPSYFSNLLPEGSLRELIAEREQVARQREFFLIARLGEDLPGAIVVRPASVLSLS
HHHHCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHEEEEECCCCCCCEEEECCHHHHCCC
GMEPLEEPQPPHAPQEQEPLRFSLAGVQLKFSMLRRDKAMTLPAGGRGGNWIVKLPDNRY
CCCCCCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHCCCCEECCCCCCCCCEEEECCCCCC
DRVPENEFSMMTWARAAGITVPEVALLDVADIQGLPEGITLRENVAYAVRRFDRPEPGRR
CCCCCCHHHHHHHHHHCCCCCCCHHHEEHHHHCCCCCCCCHHHHHHHHHHHCCCCCCCCE
VHMEDLTQVLGLYADEKYKKYNYETVANVIYKVAGLDALHEFLRRLVFITVIGNGDAHHK
ECHHHHHHHHHHHHCHHHHHCCHHHHHHHHHHHHCHHHHHHHHHHHEEEEEECCCCCCCC
NWSLLYPDGTRATLSPAYDLVSTLQYMPADTLALNFAKSKRFEDISLGSFERLARKLALP
CCEEECCCCCCCCCHHHHHHHHHHHHCCCHHHEEEHHHHCCCCCCCCCHHHHHHHHHCCC
PSDVLPVVKSAVEASLDTWSSLHAQLPLPDESRRRIEAHWKRVPLLQGQ
CHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MEPTRTTAGILDVHLGDVHVGTLTLLEDERIEFVIAEEYRQRYPRPVLGQIFEDDLSRRH
CCCCCCCCCEEEEEECCEEEEEEEEEECCCEEEEEEHHHHHHCCCCHHHHHHHHHHHHHH
VSRLRLPSYFSNLLPEGSLRELIAEREQVARQREFFLIARLGEDLPGAIVVRPASVLSLS
HHHHCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHEEEEECCCCCCCEEEECCHHHHCCC
GMEPLEEPQPPHAPQEQEPLRFSLAGVQLKFSMLRRDKAMTLPAGGRGGNWIVKLPDNRY
CCCCCCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHCCCCEECCCCCCCCCEEEECCCCCC
DRVPENEFSMMTWARAAGITVPEVALLDVADIQGLPEGITLRENVAYAVRRFDRPEPGRR
CCCCCCHHHHHHHHHHCCCCCCCHHHEEHHHHCCCCCCCCHHHHHHHHHHHCCCCCCCCE
VHMEDLTQVLGLYADEKYKKYNYETVANVIYKVAGLDALHEFLRRLVFITVIGNGDAHHK
ECHHHHHHHHHHHHCHHHHHCCHHHHHHHHHHHHCHHHHHHHHHHHEEEEEECCCCCCCC
NWSLLYPDGTRATLSPAYDLVSTLQYMPADTLALNFAKSKRFEDISLGSFERLARKLALP
CCEEECCCCCCCCCHHHHHHHHHHHHCCCHHHEEEHHHHCCCCCCCCCHHHHHHHHHCCC
PSDVLPVVKSAVEASLDTWSSLHAQLPLPDESRRRIEAHWKRVPLLQGQ
CHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9163424 [H]