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The map label for this gene is rsmB [H]

Identifier: 108760909

GI number: 108760909

Start: 4454816

End: 4456102

Strand: Direct

Name: rsmB [H]

Synonym: MXAN_3739

Alternate gene names: 108760909

Gene position: 4454816-4456102 (Clockwise)

Preceding gene: 108757664

Following gene: 108761682

Centisome position: 48.74

GC content: 70.71

Gene sequence:

>1287_bases
GTGCTTCGCGGCGAGCCTTTGAAGGCCGCGCTTGCCAACGCCTTGCGAGAGGCCAATGGCCTGGGCGGCCAGGAGCGGCG
CTTCGCCGCCATGGCCGTGCGCGAGCTGTCCCGGCACCAGCGCTTGTTGGACCTGGCGGCCCGGTTGCTGGGCCACACCA
TGGGTAAGGTGGGGTTGACGGAGGACCAGGCGCTGGTGCGCTACGCCCTCTGGCGCCGCATCTTCTGTGGTGAGGGCTGG
GCCCGCATCGGTCCCGAGGTCCGCTTGCCGGGGCCCGTGCGTCCGCGCACCATCAAGGACGATCTGCTCCAGCGCGTGGT
GGAACAGCCGCTGCCGGAGGCGCCGCTCCCGGAGTCCCAGACGGAGCGGCTGGCCATTCGCTACTCGTTCCCCAACTGGT
TGGTGCAGCGCCTGGCCCAGGTGTACCCGGAGGATGTGCTGGAAGGGCTGCTGGCGTCGCTCGATGAGGAGCCGTCGCTG
CACTTCCGCGTGCGGCCCCCGGGGACCCGGGACGCGGTGCTGGCGGCGCTGAAGGAAGAGGGCGTCAACGCCGAACCGGT
GGCCGCGGCGCCGGATGCTGTGCGGGTGACGGACTCCAGCCACCGCGTCTTCGAGACTCGGATGATGAAGTCCGGCCGGC
TCCAGGTGCAGGACGTGGGCAGCCAGCTCATCTCCGAGCTGTGCCGTCCCCGGGAGGGCTCGCTGGAGGGCTTCACCGTG
GCGGACGTGTGCGCCGGCGCGGGCGGCAAGACGCTGGCGTTGGCGGACTTCGTCGGGCCCCAGGGCAGGGTGCTGGCTGG
GGACCGTTCGCGGCGTCGGCTGGCTGAGGCGCGCGAGCGCGTGCGCCACTTCTCTCTCCGGCAGGTCGCCTTTCCGCATC
CGCTTCCGCTGTCCGACGCGGACGTCCTTCTGATCGATGCGCCGTGCAGCGGCACGGGTTCCCTGGCGCGCGAGCCGGAT
CAGAAGTGGAAGCTCACCGCTCAGGAAATCGCCAAGTACCAGGCCACGCAGTCAGAGTTGCTGGATGAGGTGTCACGCCA
GGCGAAGCCGGGGGCACTCATCGTCTATGCGACCTGCTCGGTGATGCCGGAGGAGGACGAGGCGGTGGTGGAGGCCTTCC
TCGCGAAGCATCCGGACTTCACGCTGGAGCCGGTCGAGGACGTACTCGGCGCGGAGCGGGCGGCGCTCGCCGCGCAGGGG
CCCTATCTGAAGGCGTTGCCTCCCAAGGTTCCCGGGGGAGGATTCTTCGCGGCCCGGCTGCGGAGGACAGGGGCGGGGCC
GGGTTGA

Upstream 100 bases:

>100_bases
CAACGTGGATTCCGTCTGGCCGGTAACGCCCGTAGACCCGGACCGCCTGGGTCGTCCTTCCCGTCGTGGTGCGACGGCGG
CACTCGAAGCGCACATCGCG

Downstream 100 bases:

>100_bases
CAGGCTCCGAGAACGCACGCTACGCAATCGTTGATTTCTCAAGGAGTGTGACTGACTTGGCGGCCGACTCGAAGCAGTCC
GAGGTGGTGAAGCAGATCAA

Product: RsmB/NOP family methyltransferase

Products: NA

Alternate protein names: rRNA (cytosine-C(5)-)-methyltransferase rsmB [H]

Number of amino acids: Translated: 428; Mature: 428

Protein sequence:

>428_residues
MLRGEPLKAALANALREANGLGGQERRFAAMAVRELSRHQRLLDLAARLLGHTMGKVGLTEDQALVRYALWRRIFCGEGW
ARIGPEVRLPGPVRPRTIKDDLLQRVVEQPLPEAPLPESQTERLAIRYSFPNWLVQRLAQVYPEDVLEGLLASLDEEPSL
HFRVRPPGTRDAVLAALKEEGVNAEPVAAAPDAVRVTDSSHRVFETRMMKSGRLQVQDVGSQLISELCRPREGSLEGFTV
ADVCAGAGGKTLALADFVGPQGRVLAGDRSRRRLAEARERVRHFSLRQVAFPHPLPLSDADVLLIDAPCSGTGSLAREPD
QKWKLTAQEIAKYQATQSELLDEVSRQAKPGALIVYATCSVMPEEDEAVVEAFLAKHPDFTLEPVEDVLGAERAALAAQG
PYLKALPPKVPGGGFFAARLRRTGAGPG

Sequences:

>Translated_428_residues
MLRGEPLKAALANALREANGLGGQERRFAAMAVRELSRHQRLLDLAARLLGHTMGKVGLTEDQALVRYALWRRIFCGEGW
ARIGPEVRLPGPVRPRTIKDDLLQRVVEQPLPEAPLPESQTERLAIRYSFPNWLVQRLAQVYPEDVLEGLLASLDEEPSL
HFRVRPPGTRDAVLAALKEEGVNAEPVAAAPDAVRVTDSSHRVFETRMMKSGRLQVQDVGSQLISELCRPREGSLEGFTV
ADVCAGAGGKTLALADFVGPQGRVLAGDRSRRRLAEARERVRHFSLRQVAFPHPLPLSDADVLLIDAPCSGTGSLAREPD
QKWKLTAQEIAKYQATQSELLDEVSRQAKPGALIVYATCSVMPEEDEAVVEAFLAKHPDFTLEPVEDVLGAERAALAAQG
PYLKALPPKVPGGGFFAARLRRTGAGPG
>Mature_428_residues
MLRGEPLKAALANALREANGLGGQERRFAAMAVRELSRHQRLLDLAARLLGHTMGKVGLTEDQALVRYALWRRIFCGEGW
ARIGPEVRLPGPVRPRTIKDDLLQRVVEQPLPEAPLPESQTERLAIRYSFPNWLVQRLAQVYPEDVLEGLLASLDEEPSL
HFRVRPPGTRDAVLAALKEEGVNAEPVAAAPDAVRVTDSSHRVFETRMMKSGRLQVQDVGSQLISELCRPREGSLEGFTV
ADVCAGAGGKTLALADFVGPQGRVLAGDRSRRRLAEARERVRHFSLRQVAFPHPLPLSDADVLLIDAPCSGTGSLAREPD
QKWKLTAQEIAKYQATQSELLDEVSRQAKPGALIVYATCSVMPEEDEAVVEAFLAKHPDFTLEPVEDVLGAERAALAAQG
PYLKALPPKVPGGGFFAARLRRTGAGPG

Specific function: Unknown

COG id: COG0144

COG function: function code J; tRNA and rRNA cytosine-C5-methylases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. RsmB/NOP family [H]

Homologues:

Organism=Homo sapiens, GI76150625, Length=265, Percent_Identity=30.188679245283, Blast_Score=100, Evalue=5e-21,
Organism=Homo sapiens, GI76150623, Length=265, Percent_Identity=30.188679245283, Blast_Score=100, Evalue=5e-21,
Organism=Homo sapiens, GI32698918, Length=199, Percent_Identity=30.1507537688442, Blast_Score=84, Evalue=3e-16,
Organism=Escherichia coli, GI2367212, Length=306, Percent_Identity=32.0261437908497, Blast_Score=137, Evalue=1e-33,
Organism=Escherichia coli, GI87081985, Length=201, Percent_Identity=33.8308457711443, Blast_Score=97, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI17536757, Length=267, Percent_Identity=26.9662921348315, Blast_Score=75, Evalue=5e-14,
Organism=Saccharomyces cerevisiae, GI6324268, Length=318, Percent_Identity=27.0440251572327, Blast_Score=87, Evalue=4e-18,
Organism=Drosophila melanogaster, GI22024126, Length=330, Percent_Identity=26.969696969697, Blast_Score=80, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24668781, Length=167, Percent_Identity=27.5449101796407, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI21356513, Length=167, Percent_Identity=27.5449101796407, Blast_Score=67, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001678
- InterPro:   IPR018314
- InterPro:   IPR006027
- InterPro:   IPR004573 [H]

Pfam domain/function: PF01189 Nol1_Nop2_Fmu; PF01029 NusB [H]

EC number: NA

Molecular weight: Translated: 46699; Mature: 46699

Theoretical pI: Translated: 7.54; Mature: 7.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLRGEPLKAALANALREANGLGGQERRFAAMAVRELSRHQRLLDLAARLLGHTMGKVGLT
CCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
EDQALVRYALWRRIFCGEGWARIGPEVRLPGPVRPRTIKDDLLQRVVEQPLPEAPLPESQ
CHHHHHHHHHHHHHHHCCCHHHCCCCEECCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCC
TERLAIRYSFPNWLVQRLAQVYPEDVLEGLLASLDEEPSLHFRVRPPGTRDAVLAALKEE
CCEEEEEECCHHHHHHHHHHHCHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHC
GVNAEPVAAAPDAVRVTDSSHRVFETRMMKSGRLQVQDVGSQLISELCRPREGSLEGFTV
CCCCCCCCCCCCCEEEECCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCCCH
ADVCAGAGGKTLALADFVGPQGRVLAGDRSRRRLAEARERVRHFSLRQVAFPHPLPLSDA
HHHHCCCCCCEEEEEHHCCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
DVLLIDAPCSGTGSLAREPDQKWKLTAQEIAKYQATQSELLDEVSRQAKPGALIVYATCS
CEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEC
VMPEEDEAVVEAFLAKHPDFTLEPVEDVLGAERAALAAQGPYLKALPPKVPGGGFFAARL
CCCCCHHHHHHHHHHCCCCCCCCHHHHHHCCHHHHHHCCCCCCCCCCCCCCCCCHHHHHH
RRTGAGPG
HHCCCCCC
>Mature Secondary Structure
MLRGEPLKAALANALREANGLGGQERRFAAMAVRELSRHQRLLDLAARLLGHTMGKVGLT
CCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
EDQALVRYALWRRIFCGEGWARIGPEVRLPGPVRPRTIKDDLLQRVVEQPLPEAPLPESQ
CHHHHHHHHHHHHHHHCCCHHHCCCCEECCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCC
TERLAIRYSFPNWLVQRLAQVYPEDVLEGLLASLDEEPSLHFRVRPPGTRDAVLAALKEE
CCEEEEEECCHHHHHHHHHHHCHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHC
GVNAEPVAAAPDAVRVTDSSHRVFETRMMKSGRLQVQDVGSQLISELCRPREGSLEGFTV
CCCCCCCCCCCCCEEEECCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCCCH
ADVCAGAGGKTLALADFVGPQGRVLAGDRSRRRLAEARERVRHFSLRQVAFPHPLPLSDA
HHHHCCCCCCEEEEEHHCCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
DVLLIDAPCSGTGSLAREPDQKWKLTAQEIAKYQATQSELLDEVSRQAKPGALIVYATCS
CEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEC
VMPEEDEAVVEAFLAKHPDFTLEPVEDVLGAERAALAAQGPYLKALPPKVPGGGFFAARL
CCCCCHHHHHHHHHHCCCCCCCCHHHHHHCCHHHHHHCCCCCCCCCCCCCCCCCHHHHHH
RRTGAGPG
HHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]