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The map label for this gene is rimO

Identifier: 108760706

GI number: 108760706

Start: 1736450

End: 1737880

Strand: Reverse

Name: rimO

Synonym: MXAN_1476

Alternate gene names: 108760706

Gene position: 1737880-1736450 (Counterclockwise)

Preceding gene: 108763468

Following gene: 108762892

Centisome position: 19.01

GC content: 66.95

Gene sequence:

>1431_bases
GTGGAAACCACCACCCCCAAGAGCCTGTACATGATGACCCTCGGCTGCCCGAAGAACCGGGTGGACTCCGAGGTGATGCT
GGGCACGCTGCGCCACCGCGGCTACACGCTGGTGCAGGAGGCGTCCGACGCCCAGGTCATCGTCGTCAACACGTGCGCCT
TCATCGGTCCCGCCAAGCAGGAGTCGGTGGACTCCATCCTGGAGATGGCCGAGCTGAAGAAGTCCGGCGCCTGCAAGACG
CTGGTGGTGACGGGCTGCTTGTCCCAGCGCTACGGCGAGGAGCTGTCGAAAGAGATGCCGGAGGTCGACCACTTCCTGGG
CACCAGCGCCTACGCCCAGATTGGTGACCTGCTGGCCGCCGAGGCCTCGCCGCGTCAGGTGATTCCGGACCCGGACTACA
TCCACGACGCCAATACGCCGCGCATCAACTCGATGCCGAAGTACACGGCGTACCTCAAGATTTCCGAGGGCTGCGACAAC
GCCTGTGCCTTCTGCATCATCCCCACCCTGCGCGGCGGGCAGCGCTCGCGGCCCATCGACGACATCGTCGCCGAGGCGAA
GCAGTTGGCGGACAGCGGCGTGCAGGAGCTGAACCTCGTCGCGCAGGATTTGACGGCCTACGGGCATGACCTGCCGGGCC
GGCCGAAGCTGCATGATTTGCTCAAGGCGCTGGTGCAGGTGGACGTGAAGTGGATTCGCCTCCACTACGCCTACCCGCGC
ATCTTCCCGGACGAGCTCATCGAGGTGATGGCCTCGGAGCCGAAGATTGCCCGCTACCTGGACATGCCCGTGCAGCACGT
CAGCGACAAGCTGCTGCTGTCCATGAAGCGCGGCCGCAACTCGGAGTTCCTCAAGGGCCTGCTGACCAAGCTGCGGGAGC
GCGTGCCCGGCCTGGTGATGCGCACCTCGCTCATCGTCGGCCTGCCGGGTGAGACGGAAGAGGACTTCGAGATGCTGAAG
GAGTTCGTGAAGACGCAGCGCTTCGAGCGCCTGGGCGTCTTCCAGTACTCCGACGAAGAGGGCACCGCCGCCTACGACCT
GCCGGACAAGGTGCCGCAGAAGCTCATCGAGCGCCGCTGGCGCGAGGTCATGGCCATCCAGAAGCGCATCAACCGCGAGC
AGAACAAGAAGCTCGTGGGCAAGCGCCTGGAGGTGCTCGTGGAAGGCCCCGCGCCGGAGACGGAGCACCTGCTGGTGGGC
CGCCACCAGGGCCAGGCGCCGGACATCGACGGCATGGTCTACATCAACGACGGCCTAGCGTACCCGGGGGAGATTGTCAC
CGTGGAGGTGACGGAAGCCCACGACTACGACCTGGTCGCCCGCGTGGTGGAGCGCCCGGACCCGAAGCAGCGCGAGCACA
CCGCGCGCGACGCGCACCCGGCGCCGCTGCCGGTGGCGGCGATGCAGCGTCCGGCCCCTCGCGCGGAGTAG

Upstream 100 bases:

>100_bases
AGGGCGTGCTGTCCATCCGTTACTCGAACGGCACGTCCATGAACTTCGCCTGGAGTGGGACCCACTTCTCGCGAACCGAA
CTCGGAAAGCGGTAGACGCA

Downstream 100 bases:

>100_bases
GCGCGAAGGCCCCGGACGCCGCGGGAGCCCTCAGCGCGAGGGCTCCTCCAGCACCAGGGTGCGTCCCGGGCTGACGGCGC
GCAGGCGCTCGCGCAGCTTC

Product: putative tRNA modifying protein

Products: NA

Alternate protein names: S12 MTTase; S12 methylthiotransferase; Ribosome maturation factor RimO

Number of amino acids: Translated: 476; Mature: 476

Protein sequence:

>476_residues
METTTPKSLYMMTLGCPKNRVDSEVMLGTLRHRGYTLVQEASDAQVIVVNTCAFIGPAKQESVDSILEMAELKKSGACKT
LVVTGCLSQRYGEELSKEMPEVDHFLGTSAYAQIGDLLAAEASPRQVIPDPDYIHDANTPRINSMPKYTAYLKISEGCDN
ACAFCIIPTLRGGQRSRPIDDIVAEAKQLADSGVQELNLVAQDLTAYGHDLPGRPKLHDLLKALVQVDVKWIRLHYAYPR
IFPDELIEVMASEPKIARYLDMPVQHVSDKLLLSMKRGRNSEFLKGLLTKLRERVPGLVMRTSLIVGLPGETEEDFEMLK
EFVKTQRFERLGVFQYSDEEGTAAYDLPDKVPQKLIERRWREVMAIQKRINREQNKKLVGKRLEVLVEGPAPETEHLLVG
RHQGQAPDIDGMVYINDGLAYPGEIVTVEVTEAHDYDLVARVVERPDPKQREHTARDAHPAPLPVAAMQRPAPRAE

Sequences:

>Translated_476_residues
METTTPKSLYMMTLGCPKNRVDSEVMLGTLRHRGYTLVQEASDAQVIVVNTCAFIGPAKQESVDSILEMAELKKSGACKT
LVVTGCLSQRYGEELSKEMPEVDHFLGTSAYAQIGDLLAAEASPRQVIPDPDYIHDANTPRINSMPKYTAYLKISEGCDN
ACAFCIIPTLRGGQRSRPIDDIVAEAKQLADSGVQELNLVAQDLTAYGHDLPGRPKLHDLLKALVQVDVKWIRLHYAYPR
IFPDELIEVMASEPKIARYLDMPVQHVSDKLLLSMKRGRNSEFLKGLLTKLRERVPGLVMRTSLIVGLPGETEEDFEMLK
EFVKTQRFERLGVFQYSDEEGTAAYDLPDKVPQKLIERRWREVMAIQKRINREQNKKLVGKRLEVLVEGPAPETEHLLVG
RHQGQAPDIDGMVYINDGLAYPGEIVTVEVTEAHDYDLVARVVERPDPKQREHTARDAHPAPLPVAAMQRPAPRAE
>Mature_476_residues
METTTPKSLYMMTLGCPKNRVDSEVMLGTLRHRGYTLVQEASDAQVIVVNTCAFIGPAKQESVDSILEMAELKKSGACKT
LVVTGCLSQRYGEELSKEMPEVDHFLGTSAYAQIGDLLAAEASPRQVIPDPDYIHDANTPRINSMPKYTAYLKISEGCDN
ACAFCIIPTLRGGQRSRPIDDIVAEAKQLADSGVQELNLVAQDLTAYGHDLPGRPKLHDLLKALVQVDVKWIRLHYAYPR
IFPDELIEVMASEPKIARYLDMPVQHVSDKLLLSMKRGRNSEFLKGLLTKLRERVPGLVMRTSLIVGLPGETEEDFEMLK
EFVKTQRFERLGVFQYSDEEGTAAYDLPDKVPQKLIERRWREVMAIQKRINREQNKKLVGKRLEVLVEGPAPETEHLLVG
RHQGQAPDIDGMVYINDGLAYPGEIVTVEVTEAHDYDLVARVVERPDPKQREHTARDAHPAPLPVAAMQRPAPRAE

Specific function: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12

COG id: COG0621

COG function: function code J; 2-methylthioadenine synthetase

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 TRAM domain

Homologues:

Organism=Homo sapiens, GI28872782, Length=478, Percent_Identity=29.2887029288703, Blast_Score=196, Evalue=5e-50,
Organism=Homo sapiens, GI28872784, Length=478, Percent_Identity=29.2887029288703, Blast_Score=195, Evalue=8e-50,
Organism=Homo sapiens, GI93277076, Length=458, Percent_Identity=27.7292576419214, Blast_Score=153, Evalue=3e-37,
Organism=Escherichia coli, GI1787057, Length=453, Percent_Identity=38.8520971302428, Blast_Score=304, Evalue=1e-83,
Organism=Escherichia coli, GI1786882, Length=456, Percent_Identity=29.6052631578947, Blast_Score=199, Evalue=4e-52,
Organism=Caenorhabditis elegans, GI17553146, Length=475, Percent_Identity=26.1052631578947, Blast_Score=164, Evalue=1e-40,
Organism=Caenorhabditis elegans, GI71996771, Length=295, Percent_Identity=30.5084745762712, Blast_Score=110, Evalue=2e-24,
Organism=Drosophila melanogaster, GI21356207, Length=444, Percent_Identity=28.1531531531532, Blast_Score=180, Evalue=2e-45,
Organism=Drosophila melanogaster, GI19922432, Length=456, Percent_Identity=26.9736842105263, Blast_Score=133, Evalue=3e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RIMO_MYXXD (Q1DC90)

Other databases:

- EMBL:   CP000113
- RefSeq:   YP_629733.1
- ProteinModelPortal:   Q1DC90
- SMR:   Q1DC90
- STRING:   Q1DC90
- GeneID:   4102355
- GenomeReviews:   CP000113_GR
- KEGG:   mxa:MXAN_1476
- TIGR:   MXAN_1476
- eggNOG:   COG0621
- HOGENOM:   HBG457663
- OMA:   KADAPEI
- PhylomeDB:   Q1DC90
- ProtClustDB:   CLSK944817
- BioCyc:   MXAN246197:MXAN_1476-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01865
- InterPro:   IPR006638
- InterPro:   IPR005839
- InterPro:   IPR020612
- InterPro:   IPR013848
- InterPro:   IPR012340
- InterPro:   IPR007197
- InterPro:   IPR005840
- InterPro:   IPR002792
- Gene3D:   G3DSA:2.40.50.140
- PANTHER:   PTHR11918
- SMART:   SM00729
- TIGRFAMs:   TIGR01125
- TIGRFAMs:   TIGR00089

Pfam domain/function: PF04055 Radical_SAM; PF01938 TRAM; PF00919 UPF0004

EC number: NA

Molecular weight: Translated: 53341; Mature: 53341

Theoretical pI: Translated: 5.97; Mature: 5.97

Prosite motif: PS51449 MTTASE_N; PS01278 MTTASE_RADICAL; PS50926 TRAM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
METTTPKSLYMMTLGCPKNRVDSEVMLGTLRHRGYTLVQEASDAQVIVVNTCAFIGPAKQ
CCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHCCEEEEECCCCCEEEEEECHHHCCCCHH
ESVDSILEMAELKKSGACKTLVVTGCLSQRYGEELSKEMPEVDHFLGTSAYAQIGDLLAA
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCHHHHHHHHHHHC
EASPRQVIPDPDYIHDANTPRINSMPKYTAYLKISEGCDNACAFCIIPTLRGGQRSRPID
CCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCEEEEEEECCCCCCCCCCHH
DIVAEAKQLADSGVQELNLVAQDLTAYGHDLPGRPKLHDLLKALVQVDVKWIRLHYAYPR
HHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHEEEECCCC
IFPDELIEVMASEPKIARYLDMPVQHVSDKLLLSMKRGRNSEFLKGLLTKLRERVPGLVM
CCHHHHHHHHHCCCHHHHHHCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCEE
RTSLIVGLPGETEEDFEMLKEFVKTQRFERLGVFQYSDEEGTAAYDLPDKVPQKLIERRW
EHHEEEECCCCCHHHHHHHHHHHHHHHHHHHCCEEECCCCCCEEECCCHHHHHHHHHHHH
REVMAIQKRINREQNKKLVGKRLEVLVEGPAPETEHLLVGRHQGQAPDIDGMVYINDGLA
HHHHHHHHHHCHHHHHHHHHHHHHEEECCCCCCCCCEEEECCCCCCCCCCCEEEEECCCC
YPGEIVTVEVTEAHDYDLVARVVERPDPKQREHTARDAHPAPLPVAAMQRPAPRAE
CCCCEEEEEEECCCCHHHHHHHHHCCCCHHHHHCCCCCCCCCCCHHHHCCCCCCCC
>Mature Secondary Structure
METTTPKSLYMMTLGCPKNRVDSEVMLGTLRHRGYTLVQEASDAQVIVVNTCAFIGPAKQ
CCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHCCEEEEECCCCCEEEEEECHHHCCCCHH
ESVDSILEMAELKKSGACKTLVVTGCLSQRYGEELSKEMPEVDHFLGTSAYAQIGDLLAA
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCHHHHHHHHHHHC
EASPRQVIPDPDYIHDANTPRINSMPKYTAYLKISEGCDNACAFCIIPTLRGGQRSRPID
CCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCEEEEEEECCCCCCCCCCHH
DIVAEAKQLADSGVQELNLVAQDLTAYGHDLPGRPKLHDLLKALVQVDVKWIRLHYAYPR
HHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHEEEECCCC
IFPDELIEVMASEPKIARYLDMPVQHVSDKLLLSMKRGRNSEFLKGLLTKLRERVPGLVM
CCHHHHHHHHHCCCHHHHHHCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCEE
RTSLIVGLPGETEEDFEMLKEFVKTQRFERLGVFQYSDEEGTAAYDLPDKVPQKLIERRW
EHHEEEECCCCCHHHHHHHHHHHHHHHHHHHCCEEECCCCCCEEECCCHHHHHHHHHHHH
REVMAIQKRINREQNKKLVGKRLEVLVEGPAPETEHLLVGRHQGQAPDIDGMVYINDGLA
HHHHHHHHHHCHHHHHHHHHHHHHEEECCCCCCCCCEEEECCCCCCCCCCCEEEEECCCC
YPGEIVTVEVTEAHDYDLVARVVERPDPKQREHTARDAHPAPLPVAAMQRPAPRAE
CCCCEEEEEEECCCCHHHHHHHHHCCCCHHHHHCCCCCCCCCCCHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA