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The map label for this gene is aatA [H]

Identifier: 108760679

GI number: 108760679

Start: 3935172

End: 3936362

Strand: Direct

Name: aatA [H]

Synonym: MXAN_3386

Alternate gene names: 108760679

Gene position: 3935172-3936362 (Clockwise)

Preceding gene: 108763591

Following gene: 108763738

Centisome position: 43.06

GC content: 68.77

Gene sequence:

>1191_bases
ATGAAACTCGCTCACCGGCTCCAGGCCATCAAGCCGTCTCCGACGCTCGCTCTCAACTCGCGCGCCAAGGCGCTCGTCGC
CAAGGGTGTGGATGTAGTAGTCCTGGCCGCGGGAGAGCCGGACTTCGACACGCCGGATTACGTGAAGCAGGCCGCGGTGG
ACGCACTGCGAGCGGGCTTCACCAAGTACACCCCGACCAACGGCATCCCGGAGCTGCGCGAGGCCATCTGCGCCAAGCTC
GAGCGGGACAACGGCTTGCGCTACACGCCGGACCAGGTGCTCGTCACGTCCGGTGGCAAGCAGGGCCTCTACAACTTCTG
CCAGGCGGCGCTGGAGGAGGGGGACGAGGTCATCATCTTCGCGCCCTTCTGGGTCAGCTACCCGGACATGGTGCGGCTGG
CGGGTGCCACGCCCGTCATCGTCCCCACGCGCGAGGAGGACGGCTTCGCGCCGGACCCGGACGCCATCCGCCGCGCGCTC
ACGCCGCGCACGCGCGCCGTCATCATCAACAGCCCAGGCAATCCCACCGGCGCCGTCTATTCGCGCGCGGCGCTGGAGCG
CATCGCGGAGGTGCTGCGGCCCCACGACTGCCTCATCGTCACGGACGACATCTACGAGAAGCTGCTCTACACCGACGAAC
GCCTGGGCATCAGCGACGTAGCGCCGGACCTGGTGCCGCGGCTGGTGGTCGTGAACGGCATGAGCAAGGCGTACTCCATG
ACGGGCTGGCGCATGGGCTACGTCGCCGGGCCCAAGCCGCTTTTGGCCGGCATGCAGATGGTGCAGGACCAGTCCACGTC
CAACGCCTCCTCCATTGGCCAGAAGGCCGCGCTGGCGGCGTTGCAGGGGCCGCCGGACACCATCGCCGCCATGGTGAAGG
AGTACCGCGAGCGCCGTGACTTCTTCATCGCGGGACTGAACGCGCTGGATGGCGTGCGCTGCCGGATGCCCGAGGGCGCC
TTCTACGCCTTCGCGGACGTGCGGGGCCTGCTGGGCCGGTCGTACAAGGGCAAGCCGGTGACGTCCGCGATGCAGCTGTC
GGAAATCCTCCTCGACGACTTCCGCGTCGCCGCCGTGCCCGGCGAGCCGTTCGGCGCGGAGGGCTACGTGCGCATGAGCT
TCGTCACCTCGCGCGAGGTGCTGCAGAAGGGCCTTGCCCGGCTGGGTGAGCTGGTCAAGGCCCTGAGCTGA

Upstream 100 bases:

>100_bases
TGCCGCCCAACGTGCACGAAGGTTTGAAGGCCAAGTTCGCTGGACGGAAGTAGCAGGCAGTCCCCTTGTCCGGAGTGGGG
CTCCGCGTTAGGCAGGGGAC

Downstream 100 bases:

>100_bases
CCGCTCAGTCCGTGTAGGCGAAGGCGCGGAACTCGTCGCGGTACTTGCGGTAGACGAGGACAGCGGGGCGGCCGGAGATG
TTACCCACGGCCGTCCACAC

Product: putative aspartate aminotransferase

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 396; Mature: 396

Protein sequence:

>396_residues
MKLAHRLQAIKPSPTLALNSRAKALVAKGVDVVVLAAGEPDFDTPDYVKQAAVDALRAGFTKYTPTNGIPELREAICAKL
ERDNGLRYTPDQVLVTSGGKQGLYNFCQAALEEGDEVIIFAPFWVSYPDMVRLAGATPVIVPTREEDGFAPDPDAIRRAL
TPRTRAVIINSPGNPTGAVYSRAALERIAEVLRPHDCLIVTDDIYEKLLYTDERLGISDVAPDLVPRLVVVNGMSKAYSM
TGWRMGYVAGPKPLLAGMQMVQDQSTSNASSIGQKAALAALQGPPDTIAAMVKEYRERRDFFIAGLNALDGVRCRMPEGA
FYAFADVRGLLGRSYKGKPVTSAMQLSEILLDDFRVAAVPGEPFGAEGYVRMSFVTSREVLQKGLARLGELVKALS

Sequences:

>Translated_396_residues
MKLAHRLQAIKPSPTLALNSRAKALVAKGVDVVVLAAGEPDFDTPDYVKQAAVDALRAGFTKYTPTNGIPELREAICAKL
ERDNGLRYTPDQVLVTSGGKQGLYNFCQAALEEGDEVIIFAPFWVSYPDMVRLAGATPVIVPTREEDGFAPDPDAIRRAL
TPRTRAVIINSPGNPTGAVYSRAALERIAEVLRPHDCLIVTDDIYEKLLYTDERLGISDVAPDLVPRLVVVNGMSKAYSM
TGWRMGYVAGPKPLLAGMQMVQDQSTSNASSIGQKAALAALQGPPDTIAAMVKEYRERRDFFIAGLNALDGVRCRMPEGA
FYAFADVRGLLGRSYKGKPVTSAMQLSEILLDDFRVAAVPGEPFGAEGYVRMSFVTSREVLQKGLARLGELVKALS
>Mature_396_residues
MKLAHRLQAIKPSPTLALNSRAKALVAKGVDVVVLAAGEPDFDTPDYVKQAAVDALRAGFTKYTPTNGIPELREAICAKL
ERDNGLRYTPDQVLVTSGGKQGLYNFCQAALEEGDEVIIFAPFWVSYPDMVRLAGATPVIVPTREEDGFAPDPDAIRRAL
TPRTRAVIINSPGNPTGAVYSRAALERIAEVLRPHDCLIVTDDIYEKLLYTDERLGISDVAPDLVPRLVVVNGMSKAYSM
TGWRMGYVAGPKPLLAGMQMVQDQSTSNASSIGQKAALAALQGPPDTIAAMVKEYRERRDFFIAGLNALDGVRCRMPEGA
FYAFADVRGLLGRSYKGKPVTSAMQLSEILLDDFRVAAVPGEPFGAEGYVRMSFVTSREVLQKGLARLGELVKALS

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI56713254, Length=398, Percent_Identity=29.6482412060301, Blast_Score=171, Evalue=1e-42,
Organism=Homo sapiens, GI56713256, Length=398, Percent_Identity=29.6482412060301, Blast_Score=171, Evalue=1e-42,
Organism=Homo sapiens, GI95147551, Length=345, Percent_Identity=28.9855072463768, Blast_Score=155, Evalue=5e-38,
Organism=Homo sapiens, GI169881279, Length=345, Percent_Identity=28.9855072463768, Blast_Score=155, Evalue=5e-38,
Organism=Homo sapiens, GI169881281, Length=344, Percent_Identity=23.8372093023256, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI7705897, Length=363, Percent_Identity=24.7933884297521, Blast_Score=79, Evalue=7e-15,
Organism=Homo sapiens, GI33469970, Length=363, Percent_Identity=24.7933884297521, Blast_Score=79, Evalue=7e-15,
Organism=Homo sapiens, GI4507369, Length=377, Percent_Identity=22.2811671087533, Blast_Score=79, Evalue=1e-14,
Organism=Homo sapiens, GI215599424, Length=394, Percent_Identity=22.8426395939086, Blast_Score=79, Evalue=1e-14,
Organism=Homo sapiens, GI19263340, Length=394, Percent_Identity=22.8426395939086, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI4885351, Length=375, Percent_Identity=24.8, Blast_Score=65, Evalue=8e-11,
Organism=Escherichia coli, GI1786816, Length=375, Percent_Identity=29.0666666666667, Blast_Score=167, Evalue=9e-43,
Organism=Escherichia coli, GI1788627, Length=369, Percent_Identity=30.3523035230352, Blast_Score=142, Evalue=4e-35,
Organism=Escherichia coli, GI1788722, Length=406, Percent_Identity=26.1083743842365, Blast_Score=137, Evalue=2e-33,
Organism=Caenorhabditis elegans, GI17567369, Length=383, Percent_Identity=26.1096605744125, Blast_Score=132, Evalue=4e-31,
Organism=Caenorhabditis elegans, GI71994472, Length=326, Percent_Identity=26.3803680981595, Blast_Score=120, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI71994476, Length=326, Percent_Identity=26.3803680981595, Blast_Score=120, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI17567663, Length=384, Percent_Identity=23.9583333333333, Blast_Score=96, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI71981209, Length=371, Percent_Identity=21.5633423180593, Blast_Score=70, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6322401, Length=392, Percent_Identity=25.765306122449, Blast_Score=132, Evalue=1e-31,
Organism=Saccharomyces cerevisiae, GI6320317, Length=355, Percent_Identity=22.8169014084507, Blast_Score=76, Evalue=1e-14,
Organism=Drosophila melanogaster, GI28573069, Length=416, Percent_Identity=30.2884615384615, Blast_Score=157, Evalue=1e-38,
Organism=Drosophila melanogaster, GI24646114, Length=416, Percent_Identity=30.2884615384615, Blast_Score=157, Evalue=1e-38,
Organism=Drosophila melanogaster, GI28573067, Length=416, Percent_Identity=30.2884615384615, Blast_Score=157, Evalue=1e-38,
Organism=Drosophila melanogaster, GI28573065, Length=416, Percent_Identity=30.2884615384615, Blast_Score=157, Evalue=1e-38,
Organism=Drosophila melanogaster, GI24641770, Length=368, Percent_Identity=23.6413043478261, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24641760, Length=368, Percent_Identity=23.6413043478261, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24641768, Length=368, Percent_Identity=23.6413043478261, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24641766, Length=368, Percent_Identity=23.6413043478261, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24641764, Length=368, Percent_Identity=23.6413043478261, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI18859735, Length=388, Percent_Identity=21.3917525773196, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI45551451, Length=368, Percent_Identity=23.6413043478261, Blast_Score=71, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 42893; Mature: 42893

Theoretical pI: Translated: 7.29; Mature: 7.29

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLAHRLQAIKPSPTLALNSRAKALVAKGVDVVVLAAGEPDFDTPDYVKQAAVDALRAGF
CCHHHHHHHCCCCCCEEECCHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHCC
TKYTPTNGIPELREAICAKLERDNGLRYTPDQVLVTSGGKQGLYNFCQAALEEGDEVIIF
CCCCCCCCCHHHHHHHHHHHHCCCCCEECCCEEEEECCCCHHHHHHHHHHHHCCCEEEEE
APFWVSYPDMVRLAGATPVIVPTREEDGFAPDPDAIRRALTPRTRAVIINSPGNPTGAVY
CCHHHCCHHHHHHCCCCEEEEECCCCCCCCCCHHHHHHHCCCCCEEEEEECCCCCCHHHH
SRAALERIAEVLRPHDCLIVTDDIYEKLLYTDERLGISDVAPDLVPRLVVVNGMSKAYSM
HHHHHHHHHHHHCCCCEEEEEHHHHHHHHHCCCCCCHHHCCHHHHHHHHHHCCCHHHHHC
TGWRMGYVAGPKPLLAGMQMVQDQSTSNASSIGQKAALAALQGPPDTIAAMVKEYRERRD
CCCEEEECCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHC
FFIAGLNALDGVRCRMPEGAFYAFADVRGLLGRSYKGKPVTSAMQLSEILLDDFRVAAVP
EEEECCCHHCCCEEECCCCCEEHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCEEEECC
GEPFGAEGYVRMSFVTSREVLQKGLARLGELVKALS
CCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKLAHRLQAIKPSPTLALNSRAKALVAKGVDVVVLAAGEPDFDTPDYVKQAAVDALRAGF
CCHHHHHHHCCCCCCEEECCHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHCC
TKYTPTNGIPELREAICAKLERDNGLRYTPDQVLVTSGGKQGLYNFCQAALEEGDEVIIF
CCCCCCCCCHHHHHHHHHHHHCCCCCEECCCEEEEECCCCHHHHHHHHHHHHCCCEEEEE
APFWVSYPDMVRLAGATPVIVPTREEDGFAPDPDAIRRALTPRTRAVIINSPGNPTGAVY
CCHHHCCHHHHHHCCCCEEEEECCCCCCCCCCHHHHHHHCCCCCEEEEEECCCCCCHHHH
SRAALERIAEVLRPHDCLIVTDDIYEKLLYTDERLGISDVAPDLVPRLVVVNGMSKAYSM
HHHHHHHHHHHHCCCCEEEEEHHHHHHHHHCCCCCCHHHCCHHHHHHHHHHCCCHHHHHC
TGWRMGYVAGPKPLLAGMQMVQDQSTSNASSIGQKAALAALQGPPDTIAAMVKEYRERRD
CCCEEEECCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHC
FFIAGLNALDGVRCRMPEGAFYAFADVRGLLGRSYKGKPVTSAMQLSEILLDDFRVAAVP
EEEECCCHHCCCEEECCCCCEEHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCEEEECC
GEPFGAEGYVRMSFVTSREVLQKGLARLGELVKALS
CCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA