Click here to switch to the map view.

The map label for this gene is panE [C]

Identifier: 108760447

GI number: 108760447

Start: 3657095

End: 3658051

Strand: Reverse

Name: panE [C]

Synonym: MXAN_3121

Alternate gene names: 108760447

Gene position: 3658051-3657095 (Counterclockwise)

Preceding gene: 108758031

Following gene: 108758152

Centisome position: 40.02

GC content: 70.32

Gene sequence:

>957_bases
ATGCGATTCGCCATCTTGGGGTCTGGAGGCGTCGGTGGTTTCTTCGGCGCGAAGCTGGTCCGCGCCGGGCATGACGTGAC
GTTCCTCGCGCGCGGAGCGCACCTGCGCGCCATGCGGGAACACGGGCTCACCATCCACGGCGCCGAAGGAGACTTCACGG
TCGCGGTCAAGGCCGACGATGACGTCCAGCGCTTCGGCCCCGTGGACGTCGTGGTCCTCGCGGTGAAGAACTACGACGTC
GCTTCCGTGCTCCCCGCGGTGAAGACGTTGCTCTCCGCGCGAGGCGCACCGGCGCCGGGCGAAACGCCGCCCTTCGTGCT
CACCTTGCAGAACGGCGTGGACAGCCCCTCCGAAGTGGCCGCCGCCGTGGGCGAAGCCGCCGTCCTGGGCGGCACCACGT
ACATCTCCACCGCCATCAGCGAGCCAGGCGTCATCACCCAGACCGGAACGAACCATCGAATCGTGCTCGGAGAAGTATTC
GGTGACACCTCGCGCATCTCCGACCGGGCACAGTCCCTGCGGGACGCGCTGGCCGGCGCGGGCATCACCGTGGAGGCCGT
GGCGGATGCGCGCGGAGCGCTCTGGGACAAGCTGTCCTTCCTCGCCTGCATGTCCGCGTTCAGCACCGCGTCCCGGCTGC
CCGTGGGCGCCCTCCGGGACAATCCGGCCTTCCGCGAGGTGTTCCGGCAAGCCGCCGCCGAGGTGCTCAGCGTCGCCGCC
GCGGAGGGCATCACCACCACGCGCACGCCGGACGCCCTGGTGCAGTACATGGACGGGCTGCCCGCCCACATGCGCCCATC
CATGCTGGGCGACCTGGAGAACGGCAAGCCGCTGGAGGTCGAATACCTCCAGGGCTCGGTGGTGCGCCGGGGCCGCGCGC
GGGGCGTCCCCACGCCGGTGATGAGCACCCTCTATGTCCTGCTGCAGCCCCACGCCCAGGGGGAACGAAAGGCCTGA

Upstream 100 bases:

>100_bases
CGACTGTGCTCCAACACAGCGGCCTCGCTCGCTGATGCGCGAAGTGCGAGCGCGTGATTCAACCCTGCCCCGCTGGGGAC
GTGCGGTTATCTTCCGCGCC

Downstream 100 bases:

>100_bases
GCCACGACGCCCGGCTGGAGGCCAGCCAACACCCTCCCCGCCTTCAGGGCTCGCGCAATCGCCGGGCCCGATGGGCATAT
GAACGTCATATGACCGAGCC

Product: 2-dehydropantoate 2-reductase

Products: NA

Alternate protein names: Ketopantoate reductase; KPA reductase; KPR [H]

Number of amino acids: Translated: 318; Mature: 318

Protein sequence:

>318_residues
MRFAILGSGGVGGFFGAKLVRAGHDVTFLARGAHLRAMREHGLTIHGAEGDFTVAVKADDDVQRFGPVDVVVLAVKNYDV
ASVLPAVKTLLSARGAPAPGETPPFVLTLQNGVDSPSEVAAAVGEAAVLGGTTYISTAISEPGVITQTGTNHRIVLGEVF
GDTSRISDRAQSLRDALAGAGITVEAVADARGALWDKLSFLACMSAFSTASRLPVGALRDNPAFREVFRQAAAEVLSVAA
AEGITTTRTPDALVQYMDGLPAHMRPSMLGDLENGKPLEVEYLQGSVVRRGRARGVPTPVMSTLYVLLQPHAQGERKA

Sequences:

>Translated_318_residues
MRFAILGSGGVGGFFGAKLVRAGHDVTFLARGAHLRAMREHGLTIHGAEGDFTVAVKADDDVQRFGPVDVVVLAVKNYDV
ASVLPAVKTLLSARGAPAPGETPPFVLTLQNGVDSPSEVAAAVGEAAVLGGTTYISTAISEPGVITQTGTNHRIVLGEVF
GDTSRISDRAQSLRDALAGAGITVEAVADARGALWDKLSFLACMSAFSTASRLPVGALRDNPAFREVFRQAAAEVLSVAA
AEGITTTRTPDALVQYMDGLPAHMRPSMLGDLENGKPLEVEYLQGSVVRRGRARGVPTPVMSTLYVLLQPHAQGERKA
>Mature_318_residues
MRFAILGSGGVGGFFGAKLVRAGHDVTFLARGAHLRAMREHGLTIHGAEGDFTVAVKADDDVQRFGPVDVVVLAVKNYDV
ASVLPAVKTLLSARGAPAPGETPPFVLTLQNGVDSPSEVAAAVGEAAVLGGTTYISTAISEPGVITQTGTNHRIVLGEVF
GDTSRISDRAQSLRDALAGAGITVEAVADARGALWDKLSFLACMSAFSTASRLPVGALRDNPAFREVFRQAAAEVLSVAA
AEGITTTRTPDALVQYMDGLPAHMRPSMLGDLENGKPLEVEYLQGSVVRRGRARGVPTPVMSTLYVLLQPHAQGERKA

Specific function: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid [H]

COG id: COG1893

COG function: function code H; Ketopantoate reductase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ketopantoate reductase family [H]

Homologues:

Organism=Escherichia coli, GI1786627, Length=314, Percent_Identity=24.203821656051, Blast_Score=75, Evalue=5e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR003710
- InterPro:   IPR013752
- InterPro:   IPR013332
- InterPro:   IPR013328
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02558 ApbA; PF08546 ApbA_C [H]

EC number: =1.1.1.169 [H]

Molecular weight: Translated: 33237; Mature: 33237

Theoretical pI: Translated: 6.90; Mature: 6.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRFAILGSGGVGGFFGAKLVRAGHDVTFLARGAHLRAMREHGLTIHGAEGDFTVAVKADD
CEEEEEECCCCCHHHHHHHHHCCCCEEEEECCHHHHHHHHCCCEEEECCCCEEEEEECCC
DVQRFGPVDVVVLAVKNYDVASVLPAVKTLLSARGAPAPGETPPFVLTLQNGVDSPSEVA
CHHHHCCEEEEEEEECCCCHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCCHHHHH
AAVGEAAVLGGTTYISTAISEPGVITQTGTNHRIVLGEVFGDTSRISDRAQSLRDALAGA
HHHCCHHHCCCHHHHHHHCCCCCEEEECCCCCEEEEEECCCCHHHHHHHHHHHHHHHHCC
GITVEAVADARGALWDKLSFLACMSAFSTASRLPVGALRDNPAFREVFRQAAAEVLSVAA
CEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
AEGITTTRTPDALVQYMDGLPAHMRPSMLGDLENGKPLEVEYLQGSVVRRGRARGVPTPV
HCCCCCCCCHHHHHHHHCCCCCCCCCHHHCCCCCCCCEEEEECCCHHHHCCCCCCCCHHH
MSTLYVLLQPHAQGERKA
HHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MRFAILGSGGVGGFFGAKLVRAGHDVTFLARGAHLRAMREHGLTIHGAEGDFTVAVKADD
CEEEEEECCCCCHHHHHHHHHCCCCEEEEECCHHHHHHHHCCCEEEECCCCEEEEEECCC
DVQRFGPVDVVVLAVKNYDVASVLPAVKTLLSARGAPAPGETPPFVLTLQNGVDSPSEVA
CHHHHCCEEEEEEEECCCCHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCCHHHHH
AAVGEAAVLGGTTYISTAISEPGVITQTGTNHRIVLGEVFGDTSRISDRAQSLRDALAGA
HHHCCHHHCCCHHHHHHHCCCCCEEEECCCCCEEEEEECCCCHHHHHHHHHHHHHHHHCC
GITVEAVADARGALWDKLSFLACMSAFSTASRLPVGALRDNPAFREVFRQAAAEVLSVAA
CEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
AEGITTTRTPDALVQYMDGLPAHMRPSMLGDLENGKPLEVEYLQGSVVRRGRARGVPTPV
HCCCCCCCCHHHHHHHHCCCCCCCCCHHHCCCCCCCCEEEEECCCHHHHCCCCCCCCHHH
MSTLYVLLQPHAQGERKA
HHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11759840 [H]