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The map label for this gene is ywlC [H]

Identifier: 108760186

GI number: 108760186

Start: 1815402

End: 1816403

Strand: Reverse

Name: ywlC [H]

Synonym: MXAN_1545

Alternate gene names: 108760186

Gene position: 1816403-1815402 (Counterclockwise)

Preceding gene: 108757879

Following gene: 108757038

Centisome position: 19.87

GC content: 70.16

Gene sequence:

>1002_bases
TTGCCCATGTTCCCTCCTGGGGCGACAGTGCGGCGGCGCATGATTGCTCCAGAGTCCCTTGAACGCGCGGTGGAATTGCT
GCGGCACGGTGGTGTCGTCGCCCTGCCGACGGAAACCGTCTACGGTCTGTCCGCCAACGCGGAGGACGAACTGGCCGTGC
GCCGCGTCTTCGCCATCAAGGGCCGCCCCGCCACCCACCCGCTCATCGTCCACATCCCAGGCGTCGAGCACCTGAACACG
TGGGCACGTGAGGTCCCGGAGGCCGCACGGAAGCTGGCCGAAGCCTTCTGGCCCGGGCCGTTGACGCTGGTGCTGCCGCG
CACGGCGCGGGCCACGGATGCCGTCACGGGTGGGCAGGACACGGTGGCTCTGCGCGTGCCGAATCACCCGGTGGCGCTCG
CAGTGCTCCAAAAGCTGGGTGGAGGGCTGGCCGCGCCGAGCGCGAACCGGTTCGGCAAGGTGAGCCCCACCACGGCGGAG
CACGTGCGGGAGGACCTGGGCGGAGACGTGGACCTCGTCCTGGATGGAGGCCCGTGCACGGTGGGGGTGGAGTCGACCAT
CGTGGACTTGAGCTCGAATGAGCCCGCGATTCTCCGGCCCGGAGGTCTGGCCGCGGAGGACGTGGAGCGGGTGCTGGGAC
GCAAGGTGCCGGTGAGGACTTCGTCCAAGGTGCGCGTGTCAGGCTCGCTGGAGTCACACTACGCGCCGCGTGCCGGCGTG
GTGCTGACCGAGCCTGTGCAGGCTGTAGCGCGCGTCCAGGAACTCCGCGGACAGGGATTGCGCGTGGGTGTCCTCGGACC
AGCGAGCCTTGCGTTGCCACCCGACGTGCCGCGCTTCGATGTGCCGGATGAGCCCGCGGGTGCCGCGCGTGTGCTGTACG
CCCGGCTGCGTGAGGCGGATACACAAGGGCACGACGTGCTGGTGGCGTGTCTTCCAGCGGAAAGCGGCCTGGGTATCGCT
GTCCGCGACAGGCTGTCGCGTGCCGCCGCTCCGCGCGGGTAG

Upstream 100 bases:

>100_bases
GGGGGGCGTCAGGCGTTCGAACGCCCCCTCCCGGGCATGCCAGGCGAAGAGGTCCTTGGCCGTGACGGGCATCCGAGTGC
GAGCATCGAAGACGTGCGAC

Downstream 100 bases:

>100_bases
CGATTACGCCAAGCAGCATGGGTCTGCCTTTGAAGGTAGGGCTTGGGGTAGCTTCCGACTGACGCCTGCACGACGTGAGT
CCGGAAAGGCCCATACTCTT

Product: Sua5/YciO/YrdC/YwlC family protein

Products: NA

Alternate protein names: t(6)A37 threonylcarbamoyladenosine biosynthesis protein YwlC [H]

Number of amino acids: Translated: 333; Mature: 332

Protein sequence:

>333_residues
MPMFPPGATVRRRMIAPESLERAVELLRHGGVVALPTETVYGLSANAEDELAVRRVFAIKGRPATHPLIVHIPGVEHLNT
WAREVPEAARKLAEAFWPGPLTLVLPRTARATDAVTGGQDTVALRVPNHPVALAVLQKLGGGLAAPSANRFGKVSPTTAE
HVREDLGGDVDLVLDGGPCTVGVESTIVDLSSNEPAILRPGGLAAEDVERVLGRKVPVRTSSKVRVSGSLESHYAPRAGV
VLTEPVQAVARVQELRGQGLRVGVLGPASLALPPDVPRFDVPDEPAGAARVLYARLREADTQGHDVLVACLPAESGLGIA
VRDRLSRAAAPRG

Sequences:

>Translated_333_residues
MPMFPPGATVRRRMIAPESLERAVELLRHGGVVALPTETVYGLSANAEDELAVRRVFAIKGRPATHPLIVHIPGVEHLNT
WAREVPEAARKLAEAFWPGPLTLVLPRTARATDAVTGGQDTVALRVPNHPVALAVLQKLGGGLAAPSANRFGKVSPTTAE
HVREDLGGDVDLVLDGGPCTVGVESTIVDLSSNEPAILRPGGLAAEDVERVLGRKVPVRTSSKVRVSGSLESHYAPRAGV
VLTEPVQAVARVQELRGQGLRVGVLGPASLALPPDVPRFDVPDEPAGAARVLYARLREADTQGHDVLVACLPAESGLGIA
VRDRLSRAAAPRG
>Mature_332_residues
PMFPPGATVRRRMIAPESLERAVELLRHGGVVALPTETVYGLSANAEDELAVRRVFAIKGRPATHPLIVHIPGVEHLNTW
AREVPEAARKLAEAFWPGPLTLVLPRTARATDAVTGGQDTVALRVPNHPVALAVLQKLGGGLAAPSANRFGKVSPTTAEH
VREDLGGDVDLVLDGGPCTVGVESTIVDLSSNEPAILRPGGLAAEDVERVLGRKVPVRTSSKVRVSGSLESHYAPRAGVV
LTEPVQAVARVQELRGQGLRVGVLGPASLALPPDVPRFDVPDEPAGAARVLYARLREADTQGHDVLVACLPAESGLGIAV
RDRLSRAAAPRG

Specific function: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (Probable) [H]

COG id: COG0009

COG function: function code J; Putative translation factor (SUA5)

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 YrdC-like domain [H]

Homologues:

Organism=Homo sapiens, GI58761510, Length=208, Percent_Identity=36.0576923076923, Blast_Score=88, Evalue=9e-18,
Organism=Escherichia coli, GI87081864, Length=188, Percent_Identity=29.2553191489362, Blast_Score=85, Evalue=8e-18,
Organism=Escherichia coli, GI2367210, Length=153, Percent_Identity=32.0261437908497, Blast_Score=84, Evalue=9e-18,
Organism=Caenorhabditis elegans, GI17537239, Length=197, Percent_Identity=35.0253807106599, Blast_Score=100, Evalue=1e-21,
Organism=Saccharomyces cerevisiae, GI6321269, Length=357, Percent_Identity=33.0532212885154, Blast_Score=164, Evalue=2e-41,
Organism=Drosophila melanogaster, GI78707274, Length=182, Percent_Identity=29.6703296703297, Blast_Score=72, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017945
- InterPro:   IPR005145
- InterPro:   IPR004388
- InterPro:   IPR006070
- InterPro:   IPR010923 [H]

Pfam domain/function: PF03481 SUA5; PF01300 Sua5_yciO_yrdC [H]

EC number: NA

Molecular weight: Translated: 35021; Mature: 34889

Theoretical pI: Translated: 8.27; Mature: 8.27

Prosite motif: PS51163 YRDC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPMFPPGATVRRRMIAPESLERAVELLRHGGVVALPTETVYGLSANAEDELAVRRVFAIK
CCCCCCCHHHHHHHCCHHHHHHHHHHHHCCCEEEECCCEEEECCCCCCHHHHHHHHEEEC
GRPATHPLIVHIPGVEHLNTWAREVPEAARKLAEAFWPGPLTLVLPRTARATDAVTGGQD
CCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCC
TVALRVPNHPVALAVLQKLGGGLAAPSANRFGKVSPTTAEHVREDLGGDVDLVLDGGPCT
EEEEECCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCEEEEEECCCEE
VGVESTIVDLSSNEPAILRPGGLAAEDVERVLGRKVPVRTSSKVRVSGSLESHYAPRAGV
ECCCEEEEEECCCCCEEECCCCCCHHHHHHHHCCCCCCCCCCEEEEECCHHHCCCCCCCE
VLTEPVQAVARVQELRGQGLRVGVLGPASLALPPDVPRFDVPDEPAGAARVLYARLREAD
EEEHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCC
TQGHDVLVACLPAESGLGIAVRDRLSRAAAPRG
CCCCEEEEEEECCCCCCCHHHHHHHHHHCCCCC
>Mature Secondary Structure 
PMFPPGATVRRRMIAPESLERAVELLRHGGVVALPTETVYGLSANAEDELAVRRVFAIK
CCCCCCHHHHHHHCCHHHHHHHHHHHHCCCEEEECCCEEEECCCCCCHHHHHHHHEEEC
GRPATHPLIVHIPGVEHLNTWAREVPEAARKLAEAFWPGPLTLVLPRTARATDAVTGGQD
CCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCC
TVALRVPNHPVALAVLQKLGGGLAAPSANRFGKVSPTTAEHVREDLGGDVDLVLDGGPCT
EEEEECCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCEEEEEECCCEE
VGVESTIVDLSSNEPAILRPGGLAAEDVERVLGRKVPVRTSSKVRVSGSLESHYAPRAGV
ECCCEEEEEECCCCCEEECCCCCCHHHHHHHHCCCCCCCCCCEEEEECCHHHCCCCCCCE
VLTEPVQAVARVQELRGQGLRVGVLGPASLALPPDVPRFDVPDEPAGAARVLYARLREAD
EEEHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCC
TQGHDVLVACLPAESGLGIAVRDRLSRAAAPRG
CCCCEEEEEEECCCCCCCHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]