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The map label for this gene is yfkN [H]

Identifier: 108760051

GI number: 108760051

Start: 6674228

End: 6675838

Strand: Direct

Name: yfkN [H]

Synonym: MXAN_5361

Alternate gene names: 108760051

Gene position: 6674228-6675838 (Clockwise)

Preceding gene: 108762871

Following gene: 108761124

Centisome position: 73.02

GC content: 72.19

Gene sequence:

>1611_bases
ATGACGAAGAAGACAGCGCTGGCCCGACGTGAGGCCCTGCTCGCGTTGGCCGCGGTCCTTGCCAGCGGATGCGCCACGAG
CCCCCCCTCCCCCACGCCCGCACCGCCTTCCGGCACGGTGCGCCTGACGCTCCTTCACCTAGCGGACGTCTACCAGGTCC
AGGCCGTCGAGGAAGGAAGGGGGGGCATGGCCCGCGCCGCCACGCTGCGCAAGCAGGTGCTTCGCGAGAGCCCCCACGTC
CTGACGCTGATGGGGGGCGACACGCTGTCTCCGTCCGTGGAGTCGCTGGTGGAGGTGGACGGCAAGGCGCTCAAGGGCCG
GCACATGGTGGACGCGTGGAATGCGTTCGGCCTGGACTATGCGGTGCTGGGCAACCACGAGTTCGACTTCGGCGACGATG
TCCTGCGTGAGCGCATCCGCGATTCCCGCTTCACGTGGCTCGGGGCCAACGTGCGGGACACGAAGTCCGGGGGCCTCTTC
GCGGGGGTCCAGGCCTCCGCGGTGCGGGAGTTGGGCGGCATCAAGCTGGGCCTCTTCGGCGTGGTGCTCCAGGAGACGAA
GGCCACCACGAAGGCCGGCAAGGACACGCTCTTCGGGGACGTCTGCGAGGCGGCCCGGGGCGAGGTGGCGAAGCTGCGCG
AGGCCGGCGCCCAGGTGGTGGTGGCCCTCACCCACCTGACGGCGGACCAGGACCGGGCGCTCACCCGCTGCGTCAAGGTG
GACGCGGTGCTCGGGGGACATGACCACGAGGCGCTGGAGGACCGCAGCACGGGCACGCCCATCTTCAAGGTGGCGGCGGA
CGCGGTGGACCTGGGCCGGCTCACGCTGGACGTGGACGCGGCGACGGCCACGGTGCGCCAGGTGACGTGGCAGACGCTGC
CGGTGACGCGGCAGGTGCCGGAGGACGCGGCCTTCAACGCGGCCATGCAGCCCTATGCCGCGCTGTTCAACCAGCTGTCC
GAGCACGTAGGCCGCTCCCCCGTGCCCCTGGAAGCGCGGGCCGCGATGGTGCGCACCCAGGAGACGAACCTGGGCTCGTT
CGTCGCGGATGCGTTCCGCGCGGCGGCCAGGGCGGACGTGGCGCTGGTCAACGCCGGGGCGCTGCGCGCGGACGCGGTGC
TGCCCGCGGGTGGTGTCACCCGGCGGGATTTGCACGCCATCCTGCCGTACGCGGATGAGCTGGTGGTGCTGGAGGTGAAG
GGGGACACGCTGCGCGCGGCGCTGGAGAACGGCGTCAGCCTCAGCCGCGAGGACTCACGGCCGGGCCGCTTTCCGCAGGT
GTCCGGGCTGGAGTTCACCTTCGATTCGGACCGGCCCGCCGGACAGCGGGTGCTGGGCGTGAAGGTGGGCGGCAGGCCGT
TGGACAAGGCGGCCACGTACCGGCTGGCGACGCTGAGCTTCCTCGCCAGCGGCAAGGACGGCTACGACATGCTGCGGAAC
CAGCCGTCCACGCCGGCCAGGGTGACGGGTAACTCGCCCCTGGACGTGCTGGCGGAGGCGTTCCGCACCGGCACGCCGTC
GCCGCATGCCCAGGCGGATGGCCGTATCTCCCGGCTCGGCACTGGCGCCCTGGCTCCCGACGCGCGTCAGCCGCCCGCGC
CGCTGAAGTAG

Upstream 100 bases:

>100_bases
ACGCGCGAGAAGTTCCCAGCGCTCGCCATCGACGCATGAGTGCGATACGCCCCACACGTTGCGCCCCACCCAGGGAGCGC
GCTGGGGAGAGCGACGCACG

Downstream 100 bases:

>100_bases
GACGGGGCGCGGCGCTCAAGGCGCCGTCCAGCCTCGCACGCGATACACCGCACGCCCCGCCAGCTCGCGCAGGGCGTCGG
TGCTCAGGTTGAGGGCCCCA

Product: putative 5`-nucleotidase

Products: NA

Alternate protein names: 2',3'-cyclic-nucleotide 2'-phosphodiesterase/3'-nucleotidase; 5'-nucleotidase [H]

Number of amino acids: Translated: 536; Mature: 535

Protein sequence:

>536_residues
MTKKTALARREALLALAAVLASGCATSPPSPTPAPPSGTVRLTLLHLADVYQVQAVEEGRGGMARAATLRKQVLRESPHV
LTLMGGDTLSPSVESLVEVDGKALKGRHMVDAWNAFGLDYAVLGNHEFDFGDDVLRERIRDSRFTWLGANVRDTKSGGLF
AGVQASAVRELGGIKLGLFGVVLQETKATTKAGKDTLFGDVCEAARGEVAKLREAGAQVVVALTHLTADQDRALTRCVKV
DAVLGGHDHEALEDRSTGTPIFKVAADAVDLGRLTLDVDAATATVRQVTWQTLPVTRQVPEDAAFNAAMQPYAALFNQLS
EHVGRSPVPLEARAAMVRTQETNLGSFVADAFRAAARADVALVNAGALRADAVLPAGGVTRRDLHAILPYADELVVLEVK
GDTLRAALENGVSLSREDSRPGRFPQVSGLEFTFDSDRPAGQRVLGVKVGGRPLDKAATYRLATLSFLASGKDGYDMLRN
QPSTPARVTGNSPLDVLAEAFRTGTPSPHAQADGRISRLGTGALAPDARQPPAPLK

Sequences:

>Translated_536_residues
MTKKTALARREALLALAAVLASGCATSPPSPTPAPPSGTVRLTLLHLADVYQVQAVEEGRGGMARAATLRKQVLRESPHV
LTLMGGDTLSPSVESLVEVDGKALKGRHMVDAWNAFGLDYAVLGNHEFDFGDDVLRERIRDSRFTWLGANVRDTKSGGLF
AGVQASAVRELGGIKLGLFGVVLQETKATTKAGKDTLFGDVCEAARGEVAKLREAGAQVVVALTHLTADQDRALTRCVKV
DAVLGGHDHEALEDRSTGTPIFKVAADAVDLGRLTLDVDAATATVRQVTWQTLPVTRQVPEDAAFNAAMQPYAALFNQLS
EHVGRSPVPLEARAAMVRTQETNLGSFVADAFRAAARADVALVNAGALRADAVLPAGGVTRRDLHAILPYADELVVLEVK
GDTLRAALENGVSLSREDSRPGRFPQVSGLEFTFDSDRPAGQRVLGVKVGGRPLDKAATYRLATLSFLASGKDGYDMLRN
QPSTPARVTGNSPLDVLAEAFRTGTPSPHAQADGRISRLGTGALAPDARQPPAPLK
>Mature_535_residues
TKKTALARREALLALAAVLASGCATSPPSPTPAPPSGTVRLTLLHLADVYQVQAVEEGRGGMARAATLRKQVLRESPHVL
TLMGGDTLSPSVESLVEVDGKALKGRHMVDAWNAFGLDYAVLGNHEFDFGDDVLRERIRDSRFTWLGANVRDTKSGGLFA
GVQASAVRELGGIKLGLFGVVLQETKATTKAGKDTLFGDVCEAARGEVAKLREAGAQVVVALTHLTADQDRALTRCVKVD
AVLGGHDHEALEDRSTGTPIFKVAADAVDLGRLTLDVDAATATVRQVTWQTLPVTRQVPEDAAFNAAMQPYAALFNQLSE
HVGRSPVPLEARAAMVRTQETNLGSFVADAFRAAARADVALVNAGALRADAVLPAGGVTRRDLHAILPYADELVVLEVKG
DTLRAALENGVSLSREDSRPGRFPQVSGLEFTFDSDRPAGQRVLGVKVGGRPLDKAATYRLATLSFLASGKDGYDMLRNQ
PSTPARVTGNSPLDVLAEAFRTGTPSPHAQADGRISRLGTGALAPDARQPPAPLK

Specific function: Catalyzes the release of inorganic phosphate from 2',3'- cyclic nucleotides through consecutive 2',3'-phosphodiesterase and 3'- (or 2') nucleotidase activities. Also possesses a 5'- nucleotidase activity. Does not catalyze the release of inorganic phospha

COG id: COG0737

COG function: function code F; 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases

Gene ontology:

Cell location: Secreted, cell wall; Peptidoglycan-anchor (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 5'-nucleotidase family [H]

Homologues:

Organism=Homo sapiens, GI4505467, Length=539, Percent_Identity=25.2319109461967, Blast_Score=139, Evalue=9e-33,
Organism=Escherichia coli, GI1786687, Length=532, Percent_Identity=25.3759398496241, Blast_Score=114, Evalue=1e-26,
Organism=Escherichia coli, GI1790658, Length=517, Percent_Identity=23.5976789168279, Blast_Score=80, Evalue=5e-16,
Organism=Drosophila melanogaster, GI19921980, Length=447, Percent_Identity=36.6890380313199, Blast_Score=259, Evalue=3e-69,
Organism=Drosophila melanogaster, GI24652512, Length=447, Percent_Identity=36.6890380313199, Blast_Score=259, Evalue=4e-69,
Organism=Drosophila melanogaster, GI161076508, Length=447, Percent_Identity=36.6890380313199, Blast_Score=258, Evalue=6e-69,
Organism=Drosophila melanogaster, GI19922446, Length=481, Percent_Identity=27.027027027027, Blast_Score=140, Evalue=2e-33,
Organism=Drosophila melanogaster, GI24654424, Length=481, Percent_Identity=27.027027027027, Blast_Score=140, Evalue=2e-33,
Organism=Drosophila melanogaster, GI221329836, Length=502, Percent_Identity=26.2948207171315, Blast_Score=132, Evalue=5e-31,
Organism=Drosophila melanogaster, GI28573524, Length=465, Percent_Identity=26.2365591397849, Blast_Score=116, Evalue=3e-26,
Organism=Drosophila melanogaster, GI24641187, Length=473, Percent_Identity=24.9471458773784, Blast_Score=112, Evalue=7e-25,
Organism=Drosophila melanogaster, GI19922444, Length=530, Percent_Identity=24.3396226415094, Blast_Score=111, Evalue=1e-24,

Paralogues:

None

Copy number: 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). 20 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008334
- InterPro:   IPR006146
- InterPro:   IPR006179
- InterPro:   IPR019931
- InterPro:   IPR004843
- InterPro:   IPR001899 [H]

Pfam domain/function: PF02872 5_nucleotid_C; PF00149 Metallophos [H]

EC number: =3.1.3.6; =3.1.4.16; =3.1.3.5 [H]

Molecular weight: Translated: 56684; Mature: 56553

Theoretical pI: Translated: 7.72; Mature: 7.72

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKKTALARREALLALAAVLASGCATSPPSPTPAPPSGTVRLTLLHLADVYQVQAVEEGR
CCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEEHHHHHHHHHHHHCCC
GGMARAATLRKQVLRESPHVLTLMGGDTLSPSVESLVEVDGKALKGRHMVDAWNAFGLDY
CCHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHCCHHHCCCCHHHHHHHCCCCE
AVLGNHEFDFGDDVLRERIRDSRFTWLGANVRDTKSGGLFAGVQASAVRELGGIKLGLFG
EEECCCCCCCCHHHHHHHHHCCCEEEECCCCCCCCCCCEEECCHHHHHHHHCCCEEHHHH
VVLQETKATTKAGKDTLFGDVCEAARGEVAKLREAGAQVVVALTHLTADQDRALTRCVKV
HHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHCCCEEEEEEEHHCCCHHHHHHHHHHH
DAVLGGHDHEALEDRSTGTPIFKVAADAVDLGRLTLDVDAATATVRQVTWQTLPVTRQVP
HHHCCCCCHHHHHCCCCCCCCEEEHHHHHHHCEEEEEECHHHHHHHHHHHHCCCCCCCCC
EDAAFNAAMQPYAALFNQLSEHVGRSPVPLEARAAMVRTQETNLGSFVADAFRAAARADV
CHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHEECCCCHHHHHHHHHHHHHHCCE
ALVNAGALRADAVLPAGGVTRRDLHAILPYADELVVLEVKGDTLRAALENGVSLSREDSR
EEEECCCCCCCCCCCCCCCCHHHHHHHCCCCCCEEEEEECCCHHHHHHHCCCCCCCCCCC
PGRFPQVSGLEFTFDSDRPAGQRVLGVKVGGRPLDKAATYRLATLSFLASGKDGYDMLRN
CCCCCCCCCEEEEECCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCHHHHHC
QPSTPARVTGNSPLDVLAEAFRTGTPSPHAQADGRISRLGTGALAPDARQPPAPLK
CCCCCCEECCCCCHHHHHHHHHCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TKKTALARREALLALAAVLASGCATSPPSPTPAPPSGTVRLTLLHLADVYQVQAVEEGR
CCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEEHHHHHHHHHHHHCCC
GGMARAATLRKQVLRESPHVLTLMGGDTLSPSVESLVEVDGKALKGRHMVDAWNAFGLDY
CCHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHCCHHHCCCCHHHHHHHCCCCE
AVLGNHEFDFGDDVLRERIRDSRFTWLGANVRDTKSGGLFAGVQASAVRELGGIKLGLFG
EEECCCCCCCCHHHHHHHHHCCCEEEECCCCCCCCCCCEEECCHHHHHHHHCCCEEHHHH
VVLQETKATTKAGKDTLFGDVCEAARGEVAKLREAGAQVVVALTHLTADQDRALTRCVKV
HHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHCCCEEEEEEEHHCCCHHHHHHHHHHH
DAVLGGHDHEALEDRSTGTPIFKVAADAVDLGRLTLDVDAATATVRQVTWQTLPVTRQVP
HHHCCCCCHHHHHCCCCCCCCEEEHHHHHHHCEEEEEECHHHHHHHHHHHHCCCCCCCCC
EDAAFNAAMQPYAALFNQLSEHVGRSPVPLEARAAMVRTQETNLGSFVADAFRAAARADV
CHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHEECCCCHHHHHHHHHHHHHHCCE
ALVNAGALRADAVLPAGGVTRRDLHAILPYADELVVLEVKGDTLRAALENGVSLSREDSR
EEEECCCCCCCCCCCCCCCCHHHHHHHCCCCCCEEEEEECCCHHHHHHHCCCCCCCCCCC
PGRFPQVSGLEFTFDSDRPAGQRVLGVKVGGRPLDKAATYRLATLSFLASGKDGYDMLRN
CCCCCCCCCEEEEECCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCHHHHHC
QPSTPARVTGNSPLDVLAEAFRTGTPSPHAQADGRISRLGTGALAPDARQPPAPLK
CCCCCCEECCCCCHHHHHHHHHCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969503; 9384377 [H]