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The map label for this gene is hppA [H]

Identifier: 108759896

GI number: 108759896

Start: 1973887

End: 1975965

Strand: Reverse

Name: hppA [H]

Synonym: MXAN_1671

Alternate gene names: 108759896

Gene position: 1975965-1973887 (Counterclockwise)

Preceding gene: 108757613

Following gene: 108759174

Centisome position: 21.62

GC content: 69.55

Gene sequence:

>2079_bases
ATGGAGTTGTCGAGTCTCGAGTCGAGTTTCTGGGCAATCGCACCGGGCGTGGTCGGCGCCGTGGGGCTGCTCTTCGCTGC
GGTCTTCTACTTCCGCGTCAAGGCGCTCCCGGAGGGTGACGCGACGATGAACCGCATCGCGGGCTACATCCGCGACGGCG
CGATGGCGTTCCTCGTCCGCGAGTACAAGGTGCTCGCCGCGTACTGCGCGGTCATCGCGGTGCTCATCGGCCTGGCGCTG
GGGCCGCTCGCCAGCGGGAGCTTCGTGCTCGGCGCGTTCCTCTCGCTGCTGGCCGGCTACATCGGCATGAAGGCCGCGAC
GTTCGCGAACGTGCGCACCGCGCAGGCCGCGCGCACCGGCTCCAAGCCGAACGCGCTGCTGGTCGCGCTCGACGGTGGCG
CGGTCATGGGCCTCGCCGTCGCCGGCCTGGGCCTCATCGGCATGGGCGGCGTCTACTACGCCTTCCAGGGGCATCCGCAG
CTTTCCCCCGTCCTCCACTCCTTCGCCGTGGGCGCCAGCTCCATCGCGCTCTTCGCCCGCGTGGGCGGCGGCATCTACAC
CAAGGCCGCTGACGTCGGCTCCGACATCGCCGGCAAGGTCATTGAGAACATCCCCGAGGACGACCCGCGCAACCCGGGCG
TCATCGCCGACAACGTGGGCGACAACGTGGGTGACGTGGCCGGCATGGGCGCCGACATCTACGAGTCCATGGTGGCCGCG
ATTGTCGCCGCCATGGCCATCGCGCTGACCGCCAGCGCCGCGGACCTCTCCCGCCTCGTGGTGGACCCCTCCGCGATCGG
AAGCGCGAAGGTGGCGGGCGTGGTGATCCCGCTGGTGCTGTCCGCCGTGGGCCTGGTGGTCAGCCTGCTGAGCATCTTCA
TCGCGCGCGCGCTCAAGCACATGAACCCCGCGCAGGTGCTGCGCAGCGCCCTCATCCTGCCCCCGGTCATCCTGGTGGGT
CTGTCCTTCGTGATGATGCAGGTGTTCGGCCTGTCCCAGGCCATCACGGTGGCGCTGGCCGCGGGCGCCTTCGGCGGCGC
CATCATCGGCCTCGTCACGGACTACTACACGTCGTCCACGCCGGTGCAGCGCATCGCGGAGGCCTCCGTCACGGGTGCCG
GCACCAACCTCATCCGCGGCCTCGCCGTCGGCATGGAGAGCGTGGGCATCCCGATGGCCACCATCGCCGTGGTGGCCTAC
ATCGCCGACCAGGCGCTTGGCCTGTACGGCATCGCGCTGGCGGCCGTGGGCATGCTGGGCGGCACCGCCGTGGTGATGAC
CGTGGATGCCTACGGCCCCATCTCCGACAACGCCGGTGGCATCTCCGAGATGTCCGGCCTGGGCCCCGAGGTCCGCGCCA
TCACCGATGAGCTGGACGCGGTGGGCAACACCACGGCGGCCATCGGCAAGGGCTTCGCCATCGGCTCGGCGACGCTCACC
GTCATCGCGCTCTTCTCCGCCTTCAACCTCGAGGTCAACCACACGCGCATCGCCGCTGGCCTGCCGGAGATGAGCCTGCA
ACTGACCAACCCGAACGTCATCGTCGGCCTGCTGCTGGGCTCCATCCTCCCGTTCCTGGTGGGCGCCTCCACGATGCTCG
CCGTGGGTCGCGCGGCCGGTGCCATCGTCGAGGAGATTGGCCGTCAGTTCCGCGAGATTCCGGGGCTGATGGAGCTCAAG
GCGGACCCGGACCCCAAGAAGATCGTCGACATCGCCACCAAGAGCGCCCTGCAAGAGATGGTCTTCCCGGGCATCATCGC
CGTCGCCGCCCCGCCCCTGGTGGGCTACCTGCTGGGCCCTGGTGCGCTGGCGGGTCTGCTGGCCGGCTCGCTCGTCGTCG
GCGCCACGATGGCCCTCTACATGGCCAACGCGGGCGGCGCGTGGGACAACGCCAAGAAGTTCATCGAGAAGGGCAAGCTG
CCGGGCCACGCGAAGGGCTCCGCGGTCCACAAGGCCGCCGTCGTCGGTGACATGGTCGGTGACCCGTTCAAGGACACCTC
CGGTCCTGGCGTGGCCATCCTCATCAAGGTCATGAGCGTCGTGTCCCTGCTCGTGGCCTCGCTCATCGCGCTGCGGTAG

Upstream 100 bases:

>100_bases
ATTGCGCTGAAATCAACTATACGCGCTCCGTACAAATTTCGCGGCACACGAGCGACCCGGTCGGCGAGGTCAGGCTCCCG
GGACGTCTCTGGAGGATTGG

Downstream 100 bases:

>100_bases
TCGCACCGGTGCAGCGCCTCGGATGCCGAGGCGCCGCGCCCCCCCGGCAGCTCGCACCGCGCGGCCCCATCAGCCGCGCG
GTGCTCCGGAGCGCTGGAGG

Product: membrane-bound proton-translocating pyrophosphatase

Products: NA

Alternate protein names: Membrane-bound sodium-translocating pyrophosphatase; Pyrophosphate-energized inorganic pyrophosphatase; Na(+)-PPase [H]

Number of amino acids: Translated: 692; Mature: 692

Protein sequence:

>692_residues
MELSSLESSFWAIAPGVVGAVGLLFAAVFYFRVKALPEGDATMNRIAGYIRDGAMAFLVREYKVLAAYCAVIAVLIGLAL
GPLASGSFVLGAFLSLLAGYIGMKAATFANVRTAQAARTGSKPNALLVALDGGAVMGLAVAGLGLIGMGGVYYAFQGHPQ
LSPVLHSFAVGASSIALFARVGGGIYTKAADVGSDIAGKVIENIPEDDPRNPGVIADNVGDNVGDVAGMGADIYESMVAA
IVAAMAIALTASAADLSRLVVDPSAIGSAKVAGVVIPLVLSAVGLVVSLLSIFIARALKHMNPAQVLRSALILPPVILVG
LSFVMMQVFGLSQAITVALAAGAFGGAIIGLVTDYYTSSTPVQRIAEASVTGAGTNLIRGLAVGMESVGIPMATIAVVAY
IADQALGLYGIALAAVGMLGGTAVVMTVDAYGPISDNAGGISEMSGLGPEVRAITDELDAVGNTTAAIGKGFAIGSATLT
VIALFSAFNLEVNHTRIAAGLPEMSLQLTNPNVIVGLLLGSILPFLVGASTMLAVGRAAGAIVEEIGRQFREIPGLMELK
ADPDPKKIVDIATKSALQEMVFPGIIAVAAPPLVGYLLGPGALAGLLAGSLVVGATMALYMANAGGAWDNAKKFIEKGKL
PGHAKGSAVHKAAVVGDMVGDPFKDTSGPGVAILIKVMSVVSLLVASLIALR

Sequences:

>Translated_692_residues
MELSSLESSFWAIAPGVVGAVGLLFAAVFYFRVKALPEGDATMNRIAGYIRDGAMAFLVREYKVLAAYCAVIAVLIGLAL
GPLASGSFVLGAFLSLLAGYIGMKAATFANVRTAQAARTGSKPNALLVALDGGAVMGLAVAGLGLIGMGGVYYAFQGHPQ
LSPVLHSFAVGASSIALFARVGGGIYTKAADVGSDIAGKVIENIPEDDPRNPGVIADNVGDNVGDVAGMGADIYESMVAA
IVAAMAIALTASAADLSRLVVDPSAIGSAKVAGVVIPLVLSAVGLVVSLLSIFIARALKHMNPAQVLRSALILPPVILVG
LSFVMMQVFGLSQAITVALAAGAFGGAIIGLVTDYYTSSTPVQRIAEASVTGAGTNLIRGLAVGMESVGIPMATIAVVAY
IADQALGLYGIALAAVGMLGGTAVVMTVDAYGPISDNAGGISEMSGLGPEVRAITDELDAVGNTTAAIGKGFAIGSATLT
VIALFSAFNLEVNHTRIAAGLPEMSLQLTNPNVIVGLLLGSILPFLVGASTMLAVGRAAGAIVEEIGRQFREIPGLMELK
ADPDPKKIVDIATKSALQEMVFPGIIAVAAPPLVGYLLGPGALAGLLAGSLVVGATMALYMANAGGAWDNAKKFIEKGKL
PGHAKGSAVHKAAVVGDMVGDPFKDTSGPGVAILIKVMSVVSLLVASLIALR
>Mature_692_residues
MELSSLESSFWAIAPGVVGAVGLLFAAVFYFRVKALPEGDATMNRIAGYIRDGAMAFLVREYKVLAAYCAVIAVLIGLAL
GPLASGSFVLGAFLSLLAGYIGMKAATFANVRTAQAARTGSKPNALLVALDGGAVMGLAVAGLGLIGMGGVYYAFQGHPQ
LSPVLHSFAVGASSIALFARVGGGIYTKAADVGSDIAGKVIENIPEDDPRNPGVIADNVGDNVGDVAGMGADIYESMVAA
IVAAMAIALTASAADLSRLVVDPSAIGSAKVAGVVIPLVLSAVGLVVSLLSIFIARALKHMNPAQVLRSALILPPVILVG
LSFVMMQVFGLSQAITVALAAGAFGGAIIGLVTDYYTSSTPVQRIAEASVTGAGTNLIRGLAVGMESVGIPMATIAVVAY
IADQALGLYGIALAAVGMLGGTAVVMTVDAYGPISDNAGGISEMSGLGPEVRAITDELDAVGNTTAAIGKGFAIGSATLT
VIALFSAFNLEVNHTRIAAGLPEMSLQLTNPNVIVGLLLGSILPFLVGASTMLAVGRAAGAIVEEIGRQFREIPGLMELK
ADPDPKKIVDIATKSALQEMVFPGIIAVAAPPLVGYLLGPGALAGLLAGSLVVGATMALYMANAGGAWDNAKKFIEKGKL
PGHAKGSAVHKAAVVGDMVGDPFKDTSGPGVAILIKVMSVVSLLVASLIALR

Specific function: Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na(+) movement across the membrane [H]

COG id: COG3808

COG function: function code C; Inorganic pyrophosphatase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-stimulated subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004131 [H]

Pfam domain/function: PF03030 H_PPase [H]

EC number: =3.6.1.1 [H]

Molecular weight: Translated: 69715; Mature: 69715

Theoretical pI: Translated: 5.72; Mature: 5.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELSSLESSFWAIAPGVVGAVGLLFAAVFYFRVKALPEGDATMNRIAGYIRDGAMAFLVR
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHH
EYKVLAAYCAVIAVLIGLALGPLASGSFVLGAFLSLLAGYIGMKAATFANVRTAQAARTG
HHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
SKPNALLVALDGGAVMGLAVAGLGLIGMGGVYYAFQGHPQLSPVLHSFAVGASSIALFAR
CCCCEEEEEECCCHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHCHHHHHHHHH
VGGGIYTKAADVGSDIAGKVIENIPEDDPRNPGVIADNVGDNVGDVAGMGADIYESMVAA
HCCCCEEHHHHCCCHHHHHHHHCCCCCCCCCCCEEECCCCCCHHHHHCCCHHHHHHHHHH
IVAAMAIALTASAADLSRLVVDPSAIGSAKVAGVVIPLVLSAVGLVVSLLSIFIARALKH
HHHHHHHHHHHHHHHHHHHHCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
MNPAQVLRSALILPPVILVGLSFVMMQVFGLSQAITVALAAGAFGGAIIGLVTDYYTSST
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
PVQRIAEASVTGAGTNLIRGLAVGMESVGIPMATIAVVAYIADQALGLYGIALAAVGMLG
HHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GTAVVMTVDAYGPISDNAGGISEMSGLGPEVRAITDELDAVGNTTAAIGKGFAIGSATLT
CCEEEEEEECCCCCCCCCCCHHHHHCCCCHHHHHHHHHHHCCCCHHHHCCCCCCHHHHHH
VIALFSAFNLEVNHTRIAAGLPEMSLQLTNPNVIVGLLLGSILPFLVGASTMLAVGRAAG
HHHHHHHHCCEECCEEHCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AIVEEIGRQFREIPGLMELKADPDPKKIVDIATKSALQEMVFPGIIAVAAPPLVGYLLGP
HHHHHHHHHHHHCCCCEEECCCCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCH
GALAGLLAGSLVVGATMALYMANAGGAWDNAKKFIEKGKLPGHAKGSAVHKAAVVGDMVG
HHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCC
DPFKDTSGPGVAILIKVMSVVSLLVASLIALR
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MELSSLESSFWAIAPGVVGAVGLLFAAVFYFRVKALPEGDATMNRIAGYIRDGAMAFLVR
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHH
EYKVLAAYCAVIAVLIGLALGPLASGSFVLGAFLSLLAGYIGMKAATFANVRTAQAARTG
HHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
SKPNALLVALDGGAVMGLAVAGLGLIGMGGVYYAFQGHPQLSPVLHSFAVGASSIALFAR
CCCCEEEEEECCCHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHCHHHHHHHHH
VGGGIYTKAADVGSDIAGKVIENIPEDDPRNPGVIADNVGDNVGDVAGMGADIYESMVAA
HCCCCEEHHHHCCCHHHHHHHHCCCCCCCCCCCEEECCCCCCHHHHHCCCHHHHHHHHHH
IVAAMAIALTASAADLSRLVVDPSAIGSAKVAGVVIPLVLSAVGLVVSLLSIFIARALKH
HHHHHHHHHHHHHHHHHHHHCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
MNPAQVLRSALILPPVILVGLSFVMMQVFGLSQAITVALAAGAFGGAIIGLVTDYYTSST
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
PVQRIAEASVTGAGTNLIRGLAVGMESVGIPMATIAVVAYIADQALGLYGIALAAVGMLG
HHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GTAVVMTVDAYGPISDNAGGISEMSGLGPEVRAITDELDAVGNTTAAIGKGFAIGSATLT
CCEEEEEEECCCCCCCCCCCHHHHHCCCCHHHHHHHHHHHCCCCHHHHCCCCCCHHHHHH
VIALFSAFNLEVNHTRIAAGLPEMSLQLTNPNVIVGLLLGSILPFLVGASTMLAVGRAAG
HHHHHHHHCCEECCEEHCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AIVEEIGRQFREIPGLMELKADPDPKKIVDIATKSALQEMVFPGIIAVAAPPLVGYLLGP
HHHHHHHHHHHHCCCCEEECCCCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCH
GALAGLLAGSLVVGATMALYMANAGGAWDNAKKFIEKGKLPGHAKGSAVHKAAVVGDMVG
HHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCC
DPFKDTSGPGVAILIKVMSVVSLLVASLIALR
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA