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The map label for this gene is pleC [H]

Identifier: 108759669

GI number: 108759669

Start: 1823753

End: 1825873

Strand: Reverse

Name: pleC [H]

Synonym: MXAN_1553

Alternate gene names: 108759669

Gene position: 1825873-1823753 (Counterclockwise)

Preceding gene: 108761596

Following gene: 108758646

Centisome position: 19.98

GC content: 69.83

Gene sequence:

>2121_bases
GTGGAGCCTGACGCAGTGGTCCCCCCCACCGCACTGCCCACCCCAACCCCCGAGCCAGACGTCGAAGCACGGCTCGCCCT
GGCCGAGCACCTGCTCGCCTGCGACGAGCCACGTCTGTGCGCGCAGCACGTGGTGGCGTGGCTCACCCGCGAGCGGCCGT
CGGACGTCGCGGCCTGCCTCGCGCGCGACAGCGGCACGGAAAGGTGGGTCTGCCTCGCGGCCCGGAACCTCTCCGAGGCC
CAGCGTGACGCCCTGGCGTTCCAGCCCGGTGAGACCTCCCATCCCCTGGCGGAGACGCTGACGCAGGGGGCGCCTCGCTT
CTTCGCCGCCCCCTGCGCCCCACTCCCAGCCGTGGGGTGCATCGCGGTACCCCTGGGCCGTCCTGGAGCGCCCGCCGCGG
GCCTGTTGCTGCTGTCCGCGGACGGCCCCACGCTGACGCCGGACGCAGCCTGGGTGAGCGCGCACGTCGGCCCCCGGCTG
GCCGCCATGCTGCCCACGGAGGACCGTGAGGTGGCGGGCGGAGAGCTGCTCCGTCGCATCATCGACACCGTGGCGGACCC
CGTGCTGCTGACGGACCTGGAGGGACGGCCCCACATCGCCAACGCCCGCGCGGAGGTATTGCTGGTGGCCGGACCGGATG
CGAGCGAAGGCCGCCGCCGGGCGACGGAGCTCAACCGGCAGGTGTTCTCCTCCGCGCTGGCCAGCTTCGCCAGCGGTGAC
ACGTCCACCGTGCGCCGCCGGGAAGTCCCGCTGGTGGACCCGGTGGAGGGAATCGACCTGCTCTTCGAGGTCGTCAGCAC
ACCCGTGCTCCAGCCGGATGGCCGCGAGTCACTGGTGAGCGTGATGCGCAACGTGACGGACCTGGGCCGCGCCACCCAGG
CGCTGGGTGAGAGCTACCGGCGCCTGCGCGACACGGAGCGGGAGGCCCGCAGCGAGCGTCACCGGCTGGACCGCGTGCTG
GACTCCGTGCCGGACCCCCTCATCCTGTCCGACCCGGCGGGCGGAATGGTGATGATGAACAGCCCGGCGGAGAAGCTCTT
CGCCACGCACCCCGACAGTGGGGAGGCGGCGCTGCGGCGGCTGCGCTCCAACAACGCGAGCTTCTCGTCGTTCCTCGCCA
ACCTGTTGGACGCGGAAGGCCGGCCCCGCTGGCGCGGACAGCTCGGGCTGGTGGACCCGGCCACGGGCGCCACGCTCCCC
ATGGAGGCCGTGGCCAACAAGGTCCTGGGCGACTCCGGTGAGCTGACGGGCATCGTCACCCTCTTCCACGACCGCAGCGA
GGCGCTGGAGAAGGCGCGGCTGTTGGAGCGGGTGAAGGAAGGTTCCGTCCACCTGGAGGCGCGCGTGCAGGCCGCCACCG
CGGAGCTGGCCGAACAGAACGAGATGCTGCGCCGGCAGGCCATCCAGGTGGAGCAGGCCAGCGCGGCCAAGTCCCAGTTC
CTGGCCAACATGTCCCATGAGTTCCGCACGCCGCTCAACGCCATCCTCGGCTACACGAACATGCTGCTGCAGGGCGTGTC
CGGCGAACTGAACCCGGCGCAGAAGCGGAACCTCACGCGCATCGACTCCAACGGCAGACACCTGCTGGAGGTCATCAACG
AGATTCTGGACATCACCCGCATCGAAGCGGGCCGCATGCCCTTGAACCTGTCGGACTTCGGCATCCCGGAGCTGCTCCAA
GAGGTGATGGCGGAGATGGACCCCATCATCGCGCGCAGCAAGCTGACGGTGAGCGCCCACCTCGGTCCGCGCGTGCCGGC
GGTGTACAGTGACCGGCAGAAGGTGAAACAAATCGTCCTCAATCTCCTGTCGAATGCGTTGAAGTTCACGCACGAAGGCT
CAGTGCAGGTGCAGGCGGAGTACGTGGCTGCTACGTCCACGCTCACCATCTCGGTGACGGACACGGGCATTGGCATCGAC
CCAGCGAACCAGGAAAAAATCTTCGAGGACTTCCAGCAGGTGGACAGCTCTCCGACCCGGGCCTATGGAGGCACGGGTCT
GGGGCTCTCCATCTGCCGTCGCCTGGCCACCATGCTGGGGGGGCGCGTCACCCTCCAGAGCACCCAGGGCGAGGGTTCGA
CATTCACCCTGCACTTTCCCAGACGCGCGAGGCGCGCATGA

Upstream 100 bases:

>100_bases
GCGAACGTCCACGGGCAGGCGCTCCAGGACTGGCCACCCGCATCCACACGCACCATCGTGGTGAAGTTCGTGGAGGTGCG
AACGCCTACCCCTCAATCCC

Downstream 100 bases:

>100_bases
TGAACCCATCTGAGACCCCGAAGCCCCTCGTGCTGGTCGTTGACGACTATCAAGATGCCCGGGAGATGTACGCCGAGTAC
CTGGAGTTCTCGGGCTTCCG

Product: sensory box histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 706; Mature: 706

Protein sequence:

>706_residues
MEPDAVVPPTALPTPTPEPDVEARLALAEHLLACDEPRLCAQHVVAWLTRERPSDVAACLARDSGTERWVCLAARNLSEA
QRDALAFQPGETSHPLAETLTQGAPRFFAAPCAPLPAVGCIAVPLGRPGAPAAGLLLLSADGPTLTPDAAWVSAHVGPRL
AAMLPTEDREVAGGELLRRIIDTVADPVLLTDLEGRPHIANARAEVLLVAGPDASEGRRRATELNRQVFSSALASFASGD
TSTVRRREVPLVDPVEGIDLLFEVVSTPVLQPDGRESLVSVMRNVTDLGRATQALGESYRRLRDTEREARSERHRLDRVL
DSVPDPLILSDPAGGMVMMNSPAEKLFATHPDSGEAALRRLRSNNASFSSFLANLLDAEGRPRWRGQLGLVDPATGATLP
MEAVANKVLGDSGELTGIVTLFHDRSEALEKARLLERVKEGSVHLEARVQAATAELAEQNEMLRRQAIQVEQASAAKSQF
LANMSHEFRTPLNAILGYTNMLLQGVSGELNPAQKRNLTRIDSNGRHLLEVINEILDITRIEAGRMPLNLSDFGIPELLQ
EVMAEMDPIIARSKLTVSAHLGPRVPAVYSDRQKVKQIVLNLLSNALKFTHEGSVQVQAEYVAATSTLTISVTDTGIGID
PANQEKIFEDFQQVDSSPTRAYGGTGLGLSICRRLATMLGGRVTLQSTQGEGSTFTLHFPRRARRA

Sequences:

>Translated_706_residues
MEPDAVVPPTALPTPTPEPDVEARLALAEHLLACDEPRLCAQHVVAWLTRERPSDVAACLARDSGTERWVCLAARNLSEA
QRDALAFQPGETSHPLAETLTQGAPRFFAAPCAPLPAVGCIAVPLGRPGAPAAGLLLLSADGPTLTPDAAWVSAHVGPRL
AAMLPTEDREVAGGELLRRIIDTVADPVLLTDLEGRPHIANARAEVLLVAGPDASEGRRRATELNRQVFSSALASFASGD
TSTVRRREVPLVDPVEGIDLLFEVVSTPVLQPDGRESLVSVMRNVTDLGRATQALGESYRRLRDTEREARSERHRLDRVL
DSVPDPLILSDPAGGMVMMNSPAEKLFATHPDSGEAALRRLRSNNASFSSFLANLLDAEGRPRWRGQLGLVDPATGATLP
MEAVANKVLGDSGELTGIVTLFHDRSEALEKARLLERVKEGSVHLEARVQAATAELAEQNEMLRRQAIQVEQASAAKSQF
LANMSHEFRTPLNAILGYTNMLLQGVSGELNPAQKRNLTRIDSNGRHLLEVINEILDITRIEAGRMPLNLSDFGIPELLQ
EVMAEMDPIIARSKLTVSAHLGPRVPAVYSDRQKVKQIVLNLLSNALKFTHEGSVQVQAEYVAATSTLTISVTDTGIGID
PANQEKIFEDFQQVDSSPTRAYGGTGLGLSICRRLATMLGGRVTLQSTQGEGSTFTLHFPRRARRA
>Mature_706_residues
MEPDAVVPPTALPTPTPEPDVEARLALAEHLLACDEPRLCAQHVVAWLTRERPSDVAACLARDSGTERWVCLAARNLSEA
QRDALAFQPGETSHPLAETLTQGAPRFFAAPCAPLPAVGCIAVPLGRPGAPAAGLLLLSADGPTLTPDAAWVSAHVGPRL
AAMLPTEDREVAGGELLRRIIDTVADPVLLTDLEGRPHIANARAEVLLVAGPDASEGRRRATELNRQVFSSALASFASGD
TSTVRRREVPLVDPVEGIDLLFEVVSTPVLQPDGRESLVSVMRNVTDLGRATQALGESYRRLRDTEREARSERHRLDRVL
DSVPDPLILSDPAGGMVMMNSPAEKLFATHPDSGEAALRRLRSNNASFSSFLANLLDAEGRPRWRGQLGLVDPATGATLP
MEAVANKVLGDSGELTGIVTLFHDRSEALEKARLLERVKEGSVHLEARVQAATAELAEQNEMLRRQAIQVEQASAAKSQF
LANMSHEFRTPLNAILGYTNMLLQGVSGELNPAQKRNLTRIDSNGRHLLEVINEILDITRIEAGRMPLNLSDFGIPELLQ
EVMAEMDPIIARSKLTVSAHLGPRVPAVYSDRQKVKQIVLNLLSNALKFTHEGSVQVQAEYVAATSTLTISVTDTGIGID
PANQEKIFEDFQQVDSSPTRAYGGTGLGLSICRRLATMLGGRVTLQSTQGEGSTFTLHFPRRARRA

Specific function: Member of the two-component regulatory system involved in the regulation of polar organelle development. PleC functions as a membrane-associated protein kinase that transfers phosphate to the response regulator pleD, leading to its activation [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1789149, Length=270, Percent_Identity=35.1851851851852, Blast_Score=168, Evalue=1e-42,
Organism=Escherichia coli, GI145693157, Length=289, Percent_Identity=32.5259515570934, Blast_Score=156, Evalue=5e-39,
Organism=Escherichia coli, GI87081816, Length=265, Percent_Identity=38.8679245283019, Blast_Score=146, Evalue=4e-36,
Organism=Escherichia coli, GI1788713, Length=393, Percent_Identity=28.7531806615776, Blast_Score=135, Evalue=1e-32,
Organism=Escherichia coli, GI48994928, Length=246, Percent_Identity=36.1788617886179, Blast_Score=134, Evalue=1e-32,
Organism=Escherichia coli, GI1786600, Length=321, Percent_Identity=26.791277258567, Blast_Score=101, Evalue=2e-22,
Organism=Escherichia coli, GI1788549, Length=417, Percent_Identity=24.220623501199, Blast_Score=100, Evalue=5e-22,
Organism=Escherichia coli, GI1787894, Length=265, Percent_Identity=27.5471698113208, Blast_Score=94, Evalue=3e-20,
Organism=Escherichia coli, GI1786912, Length=237, Percent_Identity=24.0506329113924, Blast_Score=86, Evalue=1e-17,
Organism=Escherichia coli, GI1788393, Length=247, Percent_Identity=25.9109311740891, Blast_Score=83, Evalue=6e-17,
Organism=Escherichia coli, GI1790346, Length=239, Percent_Identity=26.7782426778243, Blast_Score=83, Evalue=8e-17,
Organism=Escherichia coli, GI87082128, Length=227, Percent_Identity=28.6343612334802, Blast_Score=82, Evalue=8e-17,
Organism=Escherichia coli, GI1790436, Length=250, Percent_Identity=26.4, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1790861, Length=252, Percent_Identity=28.1746031746032, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI1788279, Length=235, Percent_Identity=22.9787234042553, Blast_Score=66, Evalue=8e-12,
Organism=Saccharomyces cerevisiae, GI6322044, Length=76, Percent_Identity=53.9473684210526, Blast_Score=86, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 76243; Mature: 76243

Theoretical pI: Translated: 5.57; Mature: 5.57

Prosite motif: PS50112 PAS ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEPDAVVPPTALPTPTPEPDVEARLALAEHLLACDEPRLCAQHVVAWLTRERPSDVAACL
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCHHHHHHH
ARDSGTERWVCLAARNLSEAQRDALAFQPGETSHPLAETLTQGAPRFFAAPCAPLPAVGC
HCCCCCCCEEEEEHHHHHHHHHHHEEECCCCCCCHHHHHHHCCCCCEEECCCCCCCCCCE
IAVPLGRPGAPAAGLLLLSADGPTLTPDAAWVSAHVGPRLAAMLPTEDREVAGGELLRRI
EEEECCCCCCCCCCEEEEECCCCCCCCCHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHH
IDTVADPVLLTDLEGRPHIANARAEVLLVAGPDASEGRRRATELNRQVFSSALASFASGD
HHHHCCCEEEECCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCC
TSTVRRREVPLVDPVEGIDLLFEVVSTPVLQPDGRESLVSVMRNVTDLGRATQALGESYR
HHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
RLRDTEREARSERHRLDRVLDSVPDPLILSDPAGGMVMMNSPAEKLFATHPDSGEAALRR
HHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCEEEECCCHHHHHCCCCCCHHHHHHH
LRSNNASFSSFLANLLDAEGRPRWRGQLGLVDPATGATLPMEAVANKVLGDSGELTGIVT
HHCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCEEEEE
LFHDRSEALEKARLLERVKEGSVHLEARVQAATAELAEQNEMLRRQAIQVEQASAAKSQF
EECCHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LANMSHEFRTPLNAILGYTNMLLQGVSGELNPAQKRNLTRIDSNGRHLLEVINEILDITR
HHHHHHHHHCHHHHHHHHHHHHHHCCCCCCCCHHHCCCCCCCCCCHHHHHHHHHHHHHHH
IEAGRMPLNLSDFGIPELLQEVMAEMDPIIARSKLTVSAHLGPRVPAVYSDRQKVKQIVL
HCCCCCCCCCCCCCHHHHHHHHHHHHCHHHHHCEEEEEECCCCCCCHHHCCHHHHHHHHH
NLLSNALKFTHEGSVQVQAEYVAATSTLTISVTDTGIGIDPANQEKIFEDFQQVDSSPTR
HHHHHHHHHCCCCCEEEEEEEEEEEEEEEEEEECCCCCCCCCCHHHHHHHHHHHCCCCCC
AYGGTGLGLSICRRLATMLGGRVTLQSTQGEGSTFTLHFPRRARRA
CCCCCCHHHHHHHHHHHHHCCEEEEEECCCCCCEEEEECCHHHCCC
>Mature Secondary Structure
MEPDAVVPPTALPTPTPEPDVEARLALAEHLLACDEPRLCAQHVVAWLTRERPSDVAACL
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCHHHHHHH
ARDSGTERWVCLAARNLSEAQRDALAFQPGETSHPLAETLTQGAPRFFAAPCAPLPAVGC
HCCCCCCCEEEEEHHHHHHHHHHHEEECCCCCCCHHHHHHHCCCCCEEECCCCCCCCCCE
IAVPLGRPGAPAAGLLLLSADGPTLTPDAAWVSAHVGPRLAAMLPTEDREVAGGELLRRI
EEEECCCCCCCCCCEEEEECCCCCCCCCHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHH
IDTVADPVLLTDLEGRPHIANARAEVLLVAGPDASEGRRRATELNRQVFSSALASFASGD
HHHHCCCEEEECCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCC
TSTVRRREVPLVDPVEGIDLLFEVVSTPVLQPDGRESLVSVMRNVTDLGRATQALGESYR
HHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
RLRDTEREARSERHRLDRVLDSVPDPLILSDPAGGMVMMNSPAEKLFATHPDSGEAALRR
HHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCEEEECCCHHHHHCCCCCCHHHHHHH
LRSNNASFSSFLANLLDAEGRPRWRGQLGLVDPATGATLPMEAVANKVLGDSGELTGIVT
HHCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCEEEEE
LFHDRSEALEKARLLERVKEGSVHLEARVQAATAELAEQNEMLRRQAIQVEQASAAKSQF
EECCHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LANMSHEFRTPLNAILGYTNMLLQGVSGELNPAQKRNLTRIDSNGRHLLEVINEILDITR
HHHHHHHHHCHHHHHHHHHHHHHHCCCCCCCCHHHCCCCCCCCCCHHHHHHHHHHHHHHH
IEAGRMPLNLSDFGIPELLQEVMAEMDPIIARSKLTVSAHLGPRVPAVYSDRQKVKQIVL
HCCCCCCCCCCCCCHHHHHHHHHHHHCHHHHHCEEEEEECCCCCCCHHHCCHHHHHHHHH
NLLSNALKFTHEGSVQVQAEYVAATSTLTISVTDTGIGIDPANQEKIFEDFQQVDSSPTR
HHHHHHHHHCCCCCEEEEEEEEEEEEEEEEEEECCCCCCCCCCHHHHHHHHHHHCCCCCC
AYGGTGLGLSICRRLATMLGGRVTLQSTQGEGSTFTLHFPRRARRA
CCCCCCHHHHHHHHHHHHHCCEEEEEECCCCCCEEEEECCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8421698; 11259647 [H]