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The map label for this gene is mhpA [H]

Identifier: 108759611

GI number: 108759611

Start: 1872312

End: 1873889

Strand: Reverse

Name: mhpA [H]

Synonym: MXAN_1594

Alternate gene names: 108759611

Gene position: 1873889-1872312 (Counterclockwise)

Preceding gene: 108762246

Following gene: 108757117

Centisome position: 20.5

GC content: 72.37

Gene sequence:

>1578_bases
ATGTCGGCCGACATCGAGGAAGTGGATGTGGTCATCGCGGGAGGCGGGCCGGTGGGTGTGCTCACCGCCAACCTCCTGGG
ACTCCAGGGCGTGCGCGTGCTCGTCCTCGAACGGGAGGCCGCGCCGCATGGCCAACCCCGGGCCTTCTCCTGTGACGACG
AGGCCCTGCGCATCTACCAGGCCGCGGGGCTGCTCGACGTGCTGAAGCCCGACCTGCGCCAGGGCCGCCACGTCACCTTC
ACCGGCGTGGGCGGCCAACCCATTGCCCAGGTCCAACTGGGTCAGGTGGACTTCGGCTACGGCCACGCGCCCATCTGGTT
CTTCCACCAGCCGCTCCTGGAGAAGGCGCTGCGCGAGGGGCTCTCCCGCTTCCCCGCCGCTGAGCTGCGCACGGGCACCG
AGGTGGAATCACTGGAACAGGACGGCGCGGGCGTCACCGTGCGGTACCTCACGTCCGGAGTCCGGCACGGGGTGCGCGCC
CGCTACCTGGTGGCCTGTGACGGTGGGCGGAGCACGGTGCGCGCGCTGTTGGGCATCCCCATGGAAGGCCGCGGCGGCCA
GGAGCCGTGGATTGCCATCTCCGGCACCGTGGCCGAGGAAGACGCCCCCGCCGAATGTCATGTCGTCTGCGACCCGGTCC
GCCCCGGCTTCGTCGGGCGTGGTCCCGTGGGGCGGTTCCGCTGGGAGTTCCGCCTGCGCCTGGGCGAGACGGGCGAGGAG
ATGACGCAGCCCGGCACGATTCGCCGTCTGATTGGGCCTTATGTGAATCCAGACCGGGTGACGGTGGAGCGAGCGCAGCT
CTATAGCTTTCATTCGGTGGTGGCGCAGCGCTGGCGCGTGGGCCGCACCTTCCTGGCGGGAGACGCGGCCCACCTGTTGC
CGCCCTTCCTGGGTCAGGGCCTGGTGTCCGGGCTGCGCGACGCGGCGAACCTCGCGTGGAAGCTGGCGTGGGTCCTCCAG
GGCCGCGCCCCCGAGGCGCTGCTGGACACCTACGCCGTGGAGCGCCGTCCGCACGTGCGCGCCTTGCTGGAAGCCACCGC
GCGGCTGGGCTCCGTGTTCACCGCGCGCAGCACGCCCATGGCCTGGGTACGTGACACCGTGCTCCGGGGCCTCCAGGCCG
TTCCGGCCGCGCGCCGCTTCGTGGAGGGATTCCGCTTCAAGCCGGCGCCCGCCATCGAGGAAGGCTGGATGCTGGGCGGC
CGCCGCTCGGGTCGGAAGGCCGCTGAAGGCAGCTACCTTCCCCAACCGCGCGTGCGTCGTGCGTCCGGTGAGGAACACCT
GTTGGATGACAGCCTGGGCTCCGGCTTCGCCGTGCTGAGCCGGGGCGGCAGCCCGGGGACGGAGGTGGCCCGTGAGCTGG
CCGAATCCCTGGGGGCCCGCGCCGTCACCGTGCGCTCCGCGGGTGTCCCGGGCCTGGGCGACAACAGCGTGGAGGACCAC
ACCGGCAGGCTGTCCGAGTGGTTCCGAGAGCACGGCGCCGACGTGGCCGTGGTGCGGCCGGACCGCTTCGTCTTCGGCGC
GGTGCCCCTGGCCCGGATGCCCGAGCTGCGCGCGGCGCTGGGCGTGGAAGAGGCCTGA

Upstream 100 bases:

>100_bases
CTCGCTGCGCATCTTCCGCGAATCCTCGCCCATCCTCCCCGCGGGGGGCCAAGGACGTTAGACTTCTCCCCGCAGCGGAC
CTGCTTCCGGGGGGAAGTCC

Downstream 100 bases:

>100_bases
GCCGTTGCACAGACGACAGACATTGCGAGCACGGGGTCCGGAAGACCTCGGGATGCAATCTCTGACTCGCCCAAGCACAA
TCACTCTCAGCTGTCCACAC

Product: PheA/TfdB family FAD-binding monooxygenase

Products: NA

Alternate protein names: 3-HCI hydroxylase; 3-HPP hydroxylase [H]

Number of amino acids: Translated: 525; Mature: 524

Protein sequence:

>525_residues
MSADIEEVDVVIAGGGPVGVLTANLLGLQGVRVLVLEREAAPHGQPRAFSCDDEALRIYQAAGLLDVLKPDLRQGRHVTF
TGVGGQPIAQVQLGQVDFGYGHAPIWFFHQPLLEKALREGLSRFPAAELRTGTEVESLEQDGAGVTVRYLTSGVRHGVRA
RYLVACDGGRSTVRALLGIPMEGRGGQEPWIAISGTVAEEDAPAECHVVCDPVRPGFVGRGPVGRFRWEFRLRLGETGEE
MTQPGTIRRLIGPYVNPDRVTVERAQLYSFHSVVAQRWRVGRTFLAGDAAHLLPPFLGQGLVSGLRDAANLAWKLAWVLQ
GRAPEALLDTYAVERRPHVRALLEATARLGSVFTARSTPMAWVRDTVLRGLQAVPAARRFVEGFRFKPAPAIEEGWMLGG
RRSGRKAAEGSYLPQPRVRRASGEEHLLDDSLGSGFAVLSRGGSPGTEVARELAESLGARAVTVRSAGVPGLGDNSVEDH
TGRLSEWFREHGADVAVVRPDRFVFGAVPLARMPELRAALGVEEA

Sequences:

>Translated_525_residues
MSADIEEVDVVIAGGGPVGVLTANLLGLQGVRVLVLEREAAPHGQPRAFSCDDEALRIYQAAGLLDVLKPDLRQGRHVTF
TGVGGQPIAQVQLGQVDFGYGHAPIWFFHQPLLEKALREGLSRFPAAELRTGTEVESLEQDGAGVTVRYLTSGVRHGVRA
RYLVACDGGRSTVRALLGIPMEGRGGQEPWIAISGTVAEEDAPAECHVVCDPVRPGFVGRGPVGRFRWEFRLRLGETGEE
MTQPGTIRRLIGPYVNPDRVTVERAQLYSFHSVVAQRWRVGRTFLAGDAAHLLPPFLGQGLVSGLRDAANLAWKLAWVLQ
GRAPEALLDTYAVERRPHVRALLEATARLGSVFTARSTPMAWVRDTVLRGLQAVPAARRFVEGFRFKPAPAIEEGWMLGG
RRSGRKAAEGSYLPQPRVRRASGEEHLLDDSLGSGFAVLSRGGSPGTEVARELAESLGARAVTVRSAGVPGLGDNSVEDH
TGRLSEWFREHGADVAVVRPDRFVFGAVPLARMPELRAALGVEEA
>Mature_524_residues
SADIEEVDVVIAGGGPVGVLTANLLGLQGVRVLVLEREAAPHGQPRAFSCDDEALRIYQAAGLLDVLKPDLRQGRHVTFT
GVGGQPIAQVQLGQVDFGYGHAPIWFFHQPLLEKALREGLSRFPAAELRTGTEVESLEQDGAGVTVRYLTSGVRHGVRAR
YLVACDGGRSTVRALLGIPMEGRGGQEPWIAISGTVAEEDAPAECHVVCDPVRPGFVGRGPVGRFRWEFRLRLGETGEEM
TQPGTIRRLIGPYVNPDRVTVERAQLYSFHSVVAQRWRVGRTFLAGDAAHLLPPFLGQGLVSGLRDAANLAWKLAWVLQG
RAPEALLDTYAVERRPHVRALLEATARLGSVFTARSTPMAWVRDTVLRGLQAVPAARRFVEGFRFKPAPAIEEGWMLGGR
RSGRKAAEGSYLPQPRVRRASGEEHLLDDSLGSGFAVLSRGGSPGTEVARELAESLGARAVTVRSAGVPGLGDNSVEDHT
GRLSEWFREHGADVAVVRPDRFVFGAVPLARMPELRAALGVEEA

Specific function: Catalyzes the insertion of one atom of molecular oxygen into position 2 of the phenyl ring of 3-(3- hydroxyphenyl)propionate (3-HPP) and hydroxycinnamic acid (3HCI) [H]

COG id: COG0654

COG function: function code HC; 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pheA/tfdB FAD monooxygenase family [H]

Homologues:

Organism=Escherichia coli, GI1786543, Length=512, Percent_Identity=37.6953125, Blast_Score=311, Evalue=5e-86,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002938
- InterPro:   IPR003042 [H]

Pfam domain/function: PF01494 FAD_binding_3 [H]

EC number: 1.14.13.-

Molecular weight: Translated: 56735; Mature: 56604

Theoretical pI: Translated: 8.05; Mature: 8.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSADIEEVDVVIAGGGPVGVLTANLLGLQGVRVLVLEREAAPHGQPRAFSCDDEALRIYQ
CCCCCCEEEEEEECCCCHHHHHHHHHCCCCEEEEEEECCCCCCCCCCEECCCHHHHHHHH
AAGLLDVLKPDLRQGRHVTFTGVGGQPIAQVQLGQVDFGYGHAPIWFFHQPLLEKALREG
HHCHHHHHCHHHHCCCEEEEEECCCCCEEEEEECCEECCCCCCCHHHHHHHHHHHHHHHH
LSRFPAAELRTGTEVESLEQDGAGVTVRYLTSGVRHGVRARYLVACDGGRSTVRALLGIP
HHHCCHHHHCCCCCHHHHHHCCCCEEHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHCCC
MEGRGGQEPWIAISGTVAEEDAPAECHVVCDPVRPGFVGRGPVGRFRWEFRLRLGETGEE
CCCCCCCCCEEEEECCCCCCCCCCCEEEEECCCCCCCCCCCCCCCEEEEEEEEECCCCHH
MTQPGTIRRLIGPYVNPDRVTVERAQLYSFHSVVAQRWRVGRTFLAGDAAHLLPPFLGQG
HCCCHHHHHHHCCCCCCCCEEHHHHHHHHHHHHHHHHHHHCCCEECCCHHHHCCHHHHHH
LVSGLRDAANLAWKLAWVLQGRAPEALLDTYAVERRPHVRALLEATARLGSVFTARSTPM
HHHHHHHHHHHHHHEEHHHCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCH
AWVRDTVLRGLQAVPAARRFVEGFRFKPAPAIEEGWMLGGRRSGRKAAEGSYLPQPRVRR
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHH
ASGEEHLLDDSLGSGFAVLSRGGSPGTEVARELAESLGARAVTVRSAGVPGLGDNSVEDH
CCCCHHHHCCCCCCCEEEEECCCCCHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCHH
TGRLSEWFREHGADVAVVRPDRFVFGAVPLARMPELRAALGVEEA
HHHHHHHHHHHCCCEEEECCCCEEEECCCHHHCHHHHHHCCCCCC
>Mature Secondary Structure 
SADIEEVDVVIAGGGPVGVLTANLLGLQGVRVLVLEREAAPHGQPRAFSCDDEALRIYQ
CCCCCEEEEEEECCCCHHHHHHHHHCCCCEEEEEEECCCCCCCCCCEECCCHHHHHHHH
AAGLLDVLKPDLRQGRHVTFTGVGGQPIAQVQLGQVDFGYGHAPIWFFHQPLLEKALREG
HHCHHHHHCHHHHCCCEEEEEECCCCCEEEEEECCEECCCCCCCHHHHHHHHHHHHHHHH
LSRFPAAELRTGTEVESLEQDGAGVTVRYLTSGVRHGVRARYLVACDGGRSTVRALLGIP
HHHCCHHHHCCCCCHHHHHHCCCCEEHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHCCC
MEGRGGQEPWIAISGTVAEEDAPAECHVVCDPVRPGFVGRGPVGRFRWEFRLRLGETGEE
CCCCCCCCCEEEEECCCCCCCCCCCEEEEECCCCCCCCCCCCCCCEEEEEEEEECCCCHH
MTQPGTIRRLIGPYVNPDRVTVERAQLYSFHSVVAQRWRVGRTFLAGDAAHLLPPFLGQG
HCCCHHHHHHHCCCCCCCCEEHHHHHHHHHHHHHHHHHHHCCCEECCCHHHHCCHHHHHH
LVSGLRDAANLAWKLAWVLQGRAPEALLDTYAVERRPHVRALLEATARLGSVFTARSTPM
HHHHHHHHHHHHHHEEHHHCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCH
AWVRDTVLRGLQAVPAARRFVEGFRFKPAPAIEEGWMLGGRRSGRKAAEGSYLPQPRVRR
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHH
ASGEEHLLDDSLGSGFAVLSRGGSPGTEVARELAESLGARAVTVRSAGVPGLGDNSVEDH
CCCCHHHHCCCCCCCEEEEECCCCCHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCHH
TGRLSEWFREHGADVAVVRPDRFVFGAVPLARMPELRAALGVEEA
HHHHHHHHHHHCCCEEEECCCCEEEECCCHHHCHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA