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The map label for this gene is cynT [H]

Identifier: 108759591

GI number: 108759591

Start: 5981141

End: 5981881

Strand: Reverse

Name: cynT [H]

Synonym: MXAN_4783

Alternate gene names: 108759591

Gene position: 5981881-5981141 (Counterclockwise)

Preceding gene: 108760693

Following gene: 108758288

Centisome position: 65.45

GC content: 67.61

Gene sequence:

>741_bases
GTGAGGAAGCTCATTCGCGGTCTGTTGGACTTTCAACTCAACGCCCGTTCCAGCTACCGGGAGAAGTTCGCGTTGCTGGC
GCAGGAGCAGAAGCCGGATTGCCTCTTCATCGCCTGCGCGGACAGCCGCGTGGTGCCCAACCTGCTCGTGTCCATGGACC
CGGGCGACCTGTTCGTGGTCCGCAACGTCGGCAACATGGTGGCGCCGTCGGATTCGAAGGGGCAGTCGACGGGCGACCAG
TCCGAGGCGGCCGCGCTGGAGTTCTCGCTCCGCAGCCTGCCGGTGGAGGACATCGTCGTGTGCGGCCACTCGAACTGCGG
CGCGATGAAGGCCGTCCTCGCTGGCGGCGTGGGGCCTGAGAACCCGAACCTCAAGAGCTGGCTCGAGCACGGCAAGGCCG
CGCTCCAGCGGATGGATGCGAACCCGACGCTGGGGGAGGGCCGGTCGGATTACGATCGCCTGTCCCAGAACAACGTGCTG
CTGCAGTTGGAGCACATCTCCACCTATCCGTTGGTGAAGGAGCGTCTCGACGCGGGCACCCTGCGGCTGCACGGCTGGTG
GTTCGACATCGCCACCGCGCAGGTCCACGCCTGGCGCCCGTTGCTGGGCCGCTTCATCCCCATGGACGAACTGGTGGGCG
AGGCACTGCTGCGCGAGCTGGGCACGGACACGCACGCCCCCGGCGCGCTCGCCAACGGCAACGGCGCTCAGCGCATGTCG
GTGGTGGCCAGAGCTCAGTAG

Upstream 100 bases:

>100_bases
CGCTCGAAGATGTCTGGAGCCGCAAGGGCACGGTGAAGCCGAGCAGCCCCGTGGTCGTTGACGGTCCCAATCACAACTCG
CTTGTCTCTGGAGGTGCGCA

Downstream 100 bases:

>100_bases
CCCGGTGGAAGCAGGCAACCAGGGGAGCGGCTCGAATCGAGCCATTCTCCTGGTGGCCAAAGGCCGGTGAGGGGGAGAGG
ATGGGGCGCAGCTTCGATGA

Product: carbonic anhydrase

Products: NA

Alternate protein names: Carbonate dehydratase [H]

Number of amino acids: Translated: 246; Mature: 246

Protein sequence:

>246_residues
MRKLIRGLLDFQLNARSSYREKFALLAQEQKPDCLFIACADSRVVPNLLVSMDPGDLFVVRNVGNMVAPSDSKGQSTGDQ
SEAAALEFSLRSLPVEDIVVCGHSNCGAMKAVLAGGVGPENPNLKSWLEHGKAALQRMDANPTLGEGRSDYDRLSQNNVL
LQLEHISTYPLVKERLDAGTLRLHGWWFDIATAQVHAWRPLLGRFIPMDELVGEALLRELGTDTHAPGALANGNGAQRMS
VVARAQ

Sequences:

>Translated_246_residues
MRKLIRGLLDFQLNARSSYREKFALLAQEQKPDCLFIACADSRVVPNLLVSMDPGDLFVVRNVGNMVAPSDSKGQSTGDQ
SEAAALEFSLRSLPVEDIVVCGHSNCGAMKAVLAGGVGPENPNLKSWLEHGKAALQRMDANPTLGEGRSDYDRLSQNNVL
LQLEHISTYPLVKERLDAGTLRLHGWWFDIATAQVHAWRPLLGRFIPMDELVGEALLRELGTDTHAPGALANGNGAQRMS
VVARAQ
>Mature_246_residues
MRKLIRGLLDFQLNARSSYREKFALLAQEQKPDCLFIACADSRVVPNLLVSMDPGDLFVVRNVGNMVAPSDSKGQSTGDQ
SEAAALEFSLRSLPVEDIVVCGHSNCGAMKAVLAGGVGPENPNLKSWLEHGKAALQRMDANPTLGEGRSDYDRLSQNNVL
LQLEHISTYPLVKERLDAGTLRLHGWWFDIATAQVHAWRPLLGRFIPMDELVGEALLRELGTDTHAPGALANGNGAQRMS
VVARAQ

Specific function: Reversible Hydration Of Carbon Dioxide. Carbon Dioxide Formed In The Bicarbonate-Dependent Decomposition Of Cyanate By Cyanase (Cyns) Diffuses Out Of The Cell Faster Than It Would Be Hydrated To Bicarbonate, So The Apparent Function Of This Enzyme Is To C

COG id: COG0288

COG function: function code P; Carbonic anhydrase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the beta-class carbonic anhydrase family [H]

Homologues:

Organism=Escherichia coli, GI1786534, Length=208, Percent_Identity=37.9807692307692, Blast_Score=146, Evalue=1e-36,
Organism=Escherichia coli, GI1786318, Length=174, Percent_Identity=32.7586206896552, Blast_Score=84, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI25147564, Length=270, Percent_Identity=30, Blast_Score=128, Evalue=2e-30,
Organism=Caenorhabditis elegans, GI115532990, Length=252, Percent_Identity=30.1587301587302, Blast_Score=121, Evalue=4e-28,
Organism=Drosophila melanogaster, GI24645213, Length=251, Percent_Identity=28.6852589641434, Blast_Score=118, Evalue=4e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001765
- InterPro:   IPR015892 [H]

Pfam domain/function: PF00484 Pro_CA [H]

EC number: =4.2.1.1 [H]

Molecular weight: Translated: 26811; Mature: 26811

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: PS00704 PROK_CO2_ANHYDRASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKLIRGLLDFQLNARSSYREKFALLAQEQKPDCLFIACADSRVVPNLLVSMDPGDLFVV
CHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCEEEEEECCCCCCCHHEEECCCCCEEEE
RNVGNMVAPSDSKGQSTGDQSEAAALEFSLRSLPVEDIVVCGHSNCGAMKAVLAGGVGPE
ECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHCCCCCC
NPNLKSWLEHGKAALQRMDANPTLGEGRSDYDRLSQNNVLLQLEHISTYPLVKERLDAGT
CCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHCCCCEEEEEECCCCCHHHHHHCCCCE
LRLHGWWFDIATAQVHAWRPLLGRFIPMDELVGEALLRELGTDTHAPGALANGNGAQRMS
EEEEEEEEEEHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHH
VVARAQ
EEEECC
>Mature Secondary Structure
MRKLIRGLLDFQLNARSSYREKFALLAQEQKPDCLFIACADSRVVPNLLVSMDPGDLFVV
CHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCEEEEEECCCCCCCHHEEECCCCCEEEE
RNVGNMVAPSDSKGQSTGDQSEAAALEFSLRSLPVEDIVVCGHSNCGAMKAVLAGGVGPE
ECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHCCCCCC
NPNLKSWLEHGKAALQRMDANPTLGEGRSDYDRLSQNNVLLQLEHISTYPLVKERLDAGT
CCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHCCCCEEEEEECCCCCHHHHHHCCCCE
LRLHGWWFDIATAQVHAWRPLLGRFIPMDELVGEALLRELGTDTHAPGALANGNGAQRMS
EEEEEEEEEEHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHH
VVARAQ
EEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]