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The map label for this gene is ribBA [H]

Identifier: 108759578

GI number: 108759578

Start: 3963323

End: 3964444

Strand: Reverse

Name: ribBA [H]

Synonym: MXAN_3410

Alternate gene names: 108759578

Gene position: 3964444-3963323 (Counterclockwise)

Preceding gene: 108757323

Following gene: 108761483

Centisome position: 43.38

GC content: 68.54

Gene sequence:

>1122_bases
ATGAGTCACGACAGCGAGATCTCCTCCATCGACGACGCCATCCGAGACATCCAGGAGGGCAAATTCGTCATCGTCGCCGA
CGACGAGGACCGCGAGAACGAGGGCGACCTCATCATGGCCGCGGAGAAGGTGACGCCCGAGCACCTGGCCTTCATGGTGC
GCCACACCAGCGGAATCGTCTGCATGCCCATGCTGGCGGAGCGGCTGGACGAGCTCCGCCTCCCGCAGATGGTGTCGGAC
AACACCGAATCCCATCGCACCGCCTTCACCGTCTCCGTGGACTACCGCCACGACACCCACACGGGCGTATCCGCGGCGGA
CCGCGCGAAGACCATCCGCGCCCTGGTGGACCCCTCCAGCAAGGCCGACGACTTCCTGCGCCCCGGGCACATCTTCCCGC
TCCGCTACCGCGAGGGCGGCGTCCTCCGCCGGGCCGGCCACACCGAGGCCACCGTGGACCTGTCCCGCCTCGCTGGCCTG
TCCGCCTCCGGCATCCTCTGCGAGCTGGTGAAGGACGACGGCACCATGATGCGGATGCCGGACCTCAAGGTCTTCGCCCG
CGAGCACAAGCTGTCGCTCATCACCATCGCCGACCTCATCGAATACCGCCGCCGGAAGGACCGGCTGGTGCGCCGCGAGC
CCGGCCAGCAGACCGTCAACACCCGCTACGGTGAGTTCACCGCCCTCACCTATTCGTGGCTGCCCGACGGCGTGAAGTCC
CTGGTCCTGGTGAAGGGCGACCCGGCGTCGCGGCCCAGCACCCTGGTGCGCCTGCACGCGGCCTGTGCCCTGGGTGACGT
GTTCGGCTCCCCGTCGTGCAACTGCAACGTGCTGCTGGATCAGGCGCTGGCGCGCATCGCCCGCGAAGGCTCCGGCGTGC
TGGTGTACCTGCCAGGCATGCACGGGGACGACTTCGGCATCCACCACAAGCGCAACAACGACGGCAGCAGCGGCCCCACG
CGTGGCCCGCAGGAGTCGCGTGACCTGGGCATGGGCTGCCAGATTCTCACGGACCTGGGCATCCACACGCTCCAGGTGAT
GACCAACTCGGACGTCACCTACCGCGGGCTCGCGGGCTTCGGGCTCACCATCGAGAAGCGCGTCCCGCTCCAGCCGGACT
GA

Upstream 100 bases:

>100_bases
ATCATCCCTACATGCGCCCGGCTACCGGTTGGCTTGCGAGCCACCCTCGCCCACGCTACATGCGCGACTCATGCAGCCCT
CCGCCCGGACCGAAACCTCC

Downstream 100 bases:

>100_bases
CGCGCCTCTCGCCGGGCGGACCGGGCCCGTGGTTCAGCCCAGGTCCGCCAGCGCGCCCTTCACCGCGTCCAGCGTCGCGG
GCAGCTCCACGGGCGGGTTG

Product: 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II

Products: NA

Alternate protein names: 3,4-dihydroxy-2-butanone 4-phosphate synthase; DHBP synthase; GTP cyclohydrolase-2; GTP cyclohydrolase II [H]

Number of amino acids: Translated: 373; Mature: 372

Protein sequence:

>373_residues
MSHDSEISSIDDAIRDIQEGKFVIVADDEDRENEGDLIMAAEKVTPEHLAFMVRHTSGIVCMPMLAERLDELRLPQMVSD
NTESHRTAFTVSVDYRHDTHTGVSAADRAKTIRALVDPSSKADDFLRPGHIFPLRYREGGVLRRAGHTEATVDLSRLAGL
SASGILCELVKDDGTMMRMPDLKVFAREHKLSLITIADLIEYRRRKDRLVRREPGQQTVNTRYGEFTALTYSWLPDGVKS
LVLVKGDPASRPSTLVRLHAACALGDVFGSPSCNCNVLLDQALARIAREGSGVLVYLPGMHGDDFGIHHKRNNDGSSGPT
RGPQESRDLGMGCQILTDLGIHTLQVMTNSDVTYRGLAGFGLTIEKRVPLQPD

Sequences:

>Translated_373_residues
MSHDSEISSIDDAIRDIQEGKFVIVADDEDRENEGDLIMAAEKVTPEHLAFMVRHTSGIVCMPMLAERLDELRLPQMVSD
NTESHRTAFTVSVDYRHDTHTGVSAADRAKTIRALVDPSSKADDFLRPGHIFPLRYREGGVLRRAGHTEATVDLSRLAGL
SASGILCELVKDDGTMMRMPDLKVFAREHKLSLITIADLIEYRRRKDRLVRREPGQQTVNTRYGEFTALTYSWLPDGVKS
LVLVKGDPASRPSTLVRLHAACALGDVFGSPSCNCNVLLDQALARIAREGSGVLVYLPGMHGDDFGIHHKRNNDGSSGPT
RGPQESRDLGMGCQILTDLGIHTLQVMTNSDVTYRGLAGFGLTIEKRVPLQPD
>Mature_372_residues
SHDSEISSIDDAIRDIQEGKFVIVADDEDRENEGDLIMAAEKVTPEHLAFMVRHTSGIVCMPMLAERLDELRLPQMVSDN
TESHRTAFTVSVDYRHDTHTGVSAADRAKTIRALVDPSSKADDFLRPGHIFPLRYREGGVLRRAGHTEATVDLSRLAGLS
ASGILCELVKDDGTMMRMPDLKVFAREHKLSLITIADLIEYRRRKDRLVRREPGQQTVNTRYGEFTALTYSWLPDGVKSL
VLVKGDPASRPSTLVRLHAACALGDVFGSPSCNCNVLLDQALARIAREGSGVLVYLPGMHGDDFGIHHKRNNDGSSGPTR
GPQESRDLGMGCQILTDLGIHTLQVMTNSDVTYRGLAGFGLTIEKRVPLQPD

Specific function: Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate [H]

COG id: COG0108

COG function: function code H; 3,4-dihydroxy-2-butanone 4-phosphate synthase

Gene ontology:

Cell location: Membrane-Associated [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the GTP cyclohydrolase II family [H]

Homologues:

Organism=Escherichia coli, GI1789420, Length=207, Percent_Identity=48.792270531401, Blast_Score=214, Evalue=8e-57,
Organism=Escherichia coli, GI1787533, Length=160, Percent_Identity=28.75, Blast_Score=68, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6320695, Length=207, Percent_Identity=50.2415458937198, Blast_Score=201, Evalue=1e-52,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017945
- InterPro:   IPR000422
- InterPro:   IPR000926
- InterPro:   IPR016299 [H]

Pfam domain/function: PF00926 DHBP_synthase; PF00925 GTP_cyclohydro2 [H]

EC number: =4.1.99.12; =3.5.4.25 [H]

Molecular weight: Translated: 41125; Mature: 40994

Theoretical pI: Translated: 6.39; Mature: 6.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSHDSEISSIDDAIRDIQEGKFVIVADDEDRENEGDLIMAAEKVTPEHLAFMVRHTSGIV
CCCCCHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCEEEEECCCCHHHHHHHHHHCCCEE
CMPMLAERLDELRLPQMVSDNTESHRTAFTVSVDYRHDTHTGVSAADRAKTIRALVDPSS
EHHHHHHHHHHHCCCHHHCCCCCCCEEEEEEEEECCCCCCCCCCHHHHHHHHHHHCCCCC
KADDFLRPGHIFPLRYREGGVLRRAGHTEATVDLSRLAGLSASGILCELVKDDGTMMRMP
CCHHHCCCCCEEEEEECCCCEEEECCCCCCEEEHHHHCCCCCCCEEEEEECCCCCEEECC
DLKVFAREHKLSLITIADLIEYRRRKDRLVRREPGQQTVNTRYGEFTALTYSWLPDGVKS
CHHHHHHHHCEEEEHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCEEEEEEECCCCCCCE
LVLVKGDPASRPSTLVRLHAACALGDVFGSPSCNCNVLLDQALARIAREGSGVLVYLPGM
EEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCEEEEECCC
HGDDFGIHHKRNNDGSSGPTRGPQESRDLGMGCQILTDLGIHTLQVMTNSDVTYRGLAGF
CCCCCCCEECCCCCCCCCCCCCCCCHHHCCCCHHHHHHCCCEEEEEEECCCCEEEEECCC
GLTIEKRVPLQPD
CEEEECCCCCCCC
>Mature Secondary Structure 
SHDSEISSIDDAIRDIQEGKFVIVADDEDRENEGDLIMAAEKVTPEHLAFMVRHTSGIV
CCCCHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCEEEEECCCCHHHHHHHHHHCCCEE
CMPMLAERLDELRLPQMVSDNTESHRTAFTVSVDYRHDTHTGVSAADRAKTIRALVDPSS
EHHHHHHHHHHHCCCHHHCCCCCCCEEEEEEEEECCCCCCCCCCHHHHHHHHHHHCCCCC
KADDFLRPGHIFPLRYREGGVLRRAGHTEATVDLSRLAGLSASGILCELVKDDGTMMRMP
CCHHHCCCCCEEEEEECCCCEEEECCCCCCEEEHHHHCCCCCCCEEEEEECCCCCEEECC
DLKVFAREHKLSLITIADLIEYRRRKDRLVRREPGQQTVNTRYGEFTALTYSWLPDGVKS
CHHHHHHHHCEEEEHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCEEEEEEECCCCCCCE
LVLVKGDPASRPSTLVRLHAACALGDVFGSPSCNCNVLLDQALARIAREGSGVLVYLPGM
EEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCEEEEECCC
HGDDFGIHHKRNNDGSSGPTRGPQESRDLGMGCQILTDLGIHTLQVMTNSDVTYRGLAGF
CCCCCCCEECCCCCCCCCCCCCCCCHHHCCCCHHHHHHCCCEEEEEEECCCCEEEEECCC
GLTIEKRVPLQPD
CEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA