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The map label for this gene is btuE [C]

Identifier: 108759521

GI number: 108759521

Start: 2782998

End: 2783588

Strand: Direct

Name: btuE [C]

Synonym: MXAN_2389

Alternate gene names: 108759521

Gene position: 2782998-2783588 (Clockwise)

Preceding gene: 108760579

Following gene: 108760375

Centisome position: 30.45

GC content: 65.48

Gene sequence:

>591_bases
ATGAAAACCCTCCCCTTGTTGACCCTGGCCTCGGCGCTGGCCTTCACCCCGGCGCTCGCCGCGGCGCCGAAGCCTCCTCC
CCCCGCGAAGTCCGAACCCACGAGCGAGAAGAAGCCCATGTCCTTCCATCACCTCTCCGCCAACCGGCTCGACGGCAAGC
CGGAGACGCTGTCCGGCTACCAGGGCAAGGTCGTCCTGGTGGTGAACACCGCGTCGGAATGTGGCTACACGCCGCAGTAC
GCGGGCTTGGAGAAGCTCCACCAGGAATACAAGGACAAGGGCCTGGTGGTGGTGGGCTTCCCGTCCAACGACTTTGGCGG
CCAGGAGCCGGGCTCGTCGGAGGAGATCAAGAAGTTCTGTGAGCTCCGCTACAAGGTCACCTTCCCCATGTTCGAGAAGG
TGAAGACGAAGGGGGACGGCCAGTCGCCCGTCTACGCGTTCCTGTCGCAGCACCACCCCGCGCCCAAGTGGAATTTCCAC
AAGTACGTGGTGGGCAAGGACGGCCAGGTGAAGGCCGGCTTCCCCAGTGCGGTGACGCCGGACAGCGCGGAGCTGAAGGC
GGCCATCGACAGCGCGCTCGCGCAGCCATAG

Upstream 100 bases:

>100_bases
GGGTGCTCAAGTCGCTCTTTTCGGATGAGGACACACGCTCGCGTGCCGCGGCGCGGCGGGCGTGAAACGGGCGGGGGACT
GGGGCATCCTGGGGAGCGGT

Downstream 100 bases:

>100_bases
CCCCTGAGAGGGCGCGTGGGGGCTGGCCCTCTGGTCCCCGCCCTGGAGGCATGCGGCCCTGGCTGGCGCCCTGGCATGGG
CGCCGGTGGGGGCTCACCCT

Product: glutathione peroxidase family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 196; Mature: 196

Protein sequence:

>196_residues
MKTLPLLTLASALAFTPALAAAPKPPPPAKSEPTSEKKPMSFHHLSANRLDGKPETLSGYQGKVVLVVNTASECGYTPQY
AGLEKLHQEYKDKGLVVVGFPSNDFGGQEPGSSEEIKKFCELRYKVTFPMFEKVKTKGDGQSPVYAFLSQHHPAPKWNFH
KYVVGKDGQVKAGFPSAVTPDSAELKAAIDSALAQP

Sequences:

>Translated_196_residues
MKTLPLLTLASALAFTPALAAAPKPPPPAKSEPTSEKKPMSFHHLSANRLDGKPETLSGYQGKVVLVVNTASECGYTPQY
AGLEKLHQEYKDKGLVVVGFPSNDFGGQEPGSSEEIKKFCELRYKVTFPMFEKVKTKGDGQSPVYAFLSQHHPAPKWNFH
KYVVGKDGQVKAGFPSAVTPDSAELKAAIDSALAQP
>Mature_196_residues
MKTLPLLTLASALAFTPALAAAPKPPPPAKSEPTSEKKPMSFHHLSANRLDGKPETLSGYQGKVVLVVNTASECGYTPQY
AGLEKLHQEYKDKGLVVVGFPSNDFGGQEPGSSEEIKKFCELRYKVTFPMFEKVKTKGDGQSPVYAFLSQHHPAPKWNFH
KYVVGKDGQVKAGFPSAVTPDSAELKAAIDSALAQP

Specific function: Not Essential For B12 Transport; However, It Is An Auxiliary Component Of The Transport System. [C]

COG id: COG0386

COG function: function code O; Glutathione peroxidase

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glutathione peroxidase family [H]

Homologues:

Organism=Homo sapiens, GI15618997, Length=150, Percent_Identity=38.6666666666667, Blast_Score=113, Evalue=9e-26,
Organism=Homo sapiens, GI192455698, Length=152, Percent_Identity=38.8157894736842, Blast_Score=106, Evalue=1e-23,
Organism=Homo sapiens, GI90903240, Length=165, Percent_Identity=36.969696969697, Blast_Score=104, Evalue=4e-23,
Organism=Homo sapiens, GI75709200, Length=158, Percent_Identity=37.3417721518987, Blast_Score=102, Evalue=2e-22,
Organism=Homo sapiens, GI90903238, Length=130, Percent_Identity=40.7692307692308, Blast_Score=94, Evalue=5e-20,
Organism=Homo sapiens, GI4557629, Length=136, Percent_Identity=38.2352941176471, Blast_Score=85, Evalue=5e-17,
Organism=Homo sapiens, GI41406084, Length=149, Percent_Identity=34.8993288590604, Blast_Score=83, Evalue=2e-16,
Organism=Homo sapiens, GI32967607, Length=185, Percent_Identity=31.3513513513514, Blast_Score=76, Evalue=2e-14,
Organism=Homo sapiens, GI6006001, Length=136, Percent_Identity=36.7647058823529, Blast_Score=75, Evalue=3e-14,
Organism=Homo sapiens, GI33186887, Length=136, Percent_Identity=33.8235294117647, Blast_Score=74, Evalue=1e-13,
Organism=Escherichia coli, GI1788003, Length=171, Percent_Identity=39.766081871345, Blast_Score=132, Evalue=1e-32,
Organism=Caenorhabditis elegans, GI17535473, Length=159, Percent_Identity=38.9937106918239, Blast_Score=115, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI17506887, Length=161, Percent_Identity=36.6459627329193, Blast_Score=110, Evalue=4e-25,
Organism=Caenorhabditis elegans, GI71993584, Length=162, Percent_Identity=32.0987654320988, Blast_Score=91, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI193210707, Length=154, Percent_Identity=33.7662337662338, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI193209493, Length=183, Percent_Identity=27.3224043715847, Blast_Score=82, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17550320, Length=220, Percent_Identity=25.4545454545455, Blast_Score=82, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI71993573, Length=108, Percent_Identity=35.1851851851852, Blast_Score=66, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6322228, Length=160, Percent_Identity=43.75, Blast_Score=140, Evalue=2e-34,
Organism=Saccharomyces cerevisiae, GI6319721, Length=161, Percent_Identity=42.8571428571429, Blast_Score=139, Evalue=2e-34,
Organism=Saccharomyces cerevisiae, GI6322826, Length=161, Percent_Identity=41.6149068322981, Blast_Score=128, Evalue=5e-31,
Organism=Drosophila melanogaster, GI85726443, Length=155, Percent_Identity=34.1935483870968, Blast_Score=99, Evalue=3e-21,
Organism=Drosophila melanogaster, GI24656772, Length=178, Percent_Identity=34.2696629213483, Blast_Score=92, Evalue=3e-19,
Organism=Drosophila melanogaster, GI24656767, Length=140, Percent_Identity=37.8571428571429, Blast_Score=89, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24656777, Length=140, Percent_Identity=37.8571428571429, Blast_Score=89, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000889
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00255 GSHPx [H]

EC number: =1.11.1.9 [H]

Molecular weight: Translated: 21156; Mature: 21156

Theoretical pI: Translated: 9.26; Mature: 9.26

Prosite motif: PS00460 GLUTATHIONE_PEROXID_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTLPLLTLASALAFTPALAAAPKPPPPAKSEPTSEKKPMSFHHLSANRLDGKPETLSGY
CCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCC
QGKVVLVVNTASECGYTPQYAGLEKLHQEYKDKGLVVVGFPSNDFGGQEPGSSEEIKKFC
CCEEEEEEECHHHCCCCCCHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCCCHHHHHHHH
ELRYKVTFPMFEKVKTKGDGQSPVYAFLSQHHPAPKWNFHKYVVGKDGQVKAGFPSAVTP
HHHEEECCHHHHHHHCCCCCCCHHHHHHHHCCCCCCCCCEEEEECCCCEEECCCCCCCCC
DSAELKAAIDSALAQP
CHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKTLPLLTLASALAFTPALAAAPKPPPPAKSEPTSEKKPMSFHHLSANRLDGKPETLSGY
CCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCC
QGKVVLVVNTASECGYTPQYAGLEKLHQEYKDKGLVVVGFPSNDFGGQEPGSSEEIKKFC
CCEEEEEEECHHHCCCCCCHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCCCHHHHHHHH
ELRYKVTFPMFEKVKTKGDGQSPVYAFLSQHHPAPKWNFHKYVVGKDGQVKAGFPSAVTP
HHHEEECCHHHHHHHCCCCCCCHHHHHHHHCCCCCCCCCEEEEECCCCEEECCCCCCCCC
DSAELKAAIDSALAQP
CHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]