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The map label for this gene is zraR [H]

Identifier: 108759510

GI number: 108759510

Start: 2926779

End: 2928185

Strand: Reverse

Name: zraR [H]

Synonym: MXAN_2516

Alternate gene names: 108759510

Gene position: 2928185-2926779 (Counterclockwise)

Preceding gene: 108760343

Following gene: 108758239

Centisome position: 32.04

GC content: 70.29

Gene sequence:

>1407_bases
ATGACATCCCCCACGGTCCTGGTCGTCGACGACGACCGCGCGAACCTCGACTCGGTCATCCGCATCTTCCAGCGTGAGGG
CATGGCCACGCTGGCCGCCGCCAACGGTACGGAGGCGCTGGAGCTGCTGCGCCGGCCGGAGGTCGCCGCCATGGTGACCG
ACCTGATGATGCCCAACATGGACGGCCAGGAGCTGCTGCGCGCCGCGCGCGCCATCCGCCCGGACGTGGAAGTGGTGCTG
ATGACGGCCTACGGCACGGTGGAGACGGCCGTGGCGGCCATGAAGGACGGCGCCTACGACTTCATCACCAAGCCCCTCAA
GCGCCACGCGCTGGTGAAGGCCATCCAGAAGGCGCTGGAGAAGCGAGCGCTGGTGGCGGAGAACCAGTCGCTCAAGGCGA
AGTTGGCGGAGATGAACGCGGCGGGTGGGCGCTCCATGGTGGGCCAGTCCCCCGCCTTCCGCGCCATGCTGGACACCATC
CGCCAGGCGGCCCCCTCCACCGCCACGGTGCTGCTGCTGGGTGAGTCCGGCACGGGAAAGGAGCTGGCCGCGCGCTCCGT
GCACGAGTTCTCCCAGCGGGTCCGCGGGCCCTTCGTCGCCGTCAACTGCGGCGCGCTGCCGGAGAACATCCTGGAGGCGG
AACTCTTCGGCGTGGAGCGCGGCGCATTCACCGGCGCGGTGGCCCGGCGAGAGGGCCGCTTCGAGCGTGCCCACGGTGGC
ACCCTCTTCCTGGACGAAGTCGGTGAGATGCCGCTGCCCGCCCAGGTGAAGCTGCTCCGCGCGCTGGCCGAGGGCGAAAT
CGAGCGGCTGGGTGGCACGCAGACGGTGAAGGTGGACGTGCGCCTCGTCGCCGCCACCAACAAGGACCTGCAGAAGGAGG
TGGCCGAAGGCCGCTTCCGCGAGGACCTCTACTACCGGCTCAACGTGGTGGAGATTCGCGTGCCCGCGCTCGCCTCGCGC
CGCGAGGACATTCCCCTGCTGGCGGACGCCTTCCTGCGCCGCTTCGCCGCCAAGAACGGCAAGGTGCTGCGCGGCTTCTC
GCAGGAGGCGATGGGCGTGCTGGAGAATTACGCCTGGCCCGGCAACGTGCGCGAACTGGAGCACGCGGTGGAGCGCGCGG
TGGTGCTGGCGCGCGGCGAGGTGCTGGACGCCAGTGACCTGCCTGAATCCGTGCGCAAGGGCCCGCTGGGCTCAGCCGGA
CAGCTCGTCATTCCCATTGGGACGCCCATGGAGGAAATCGAGCGCCGGGTGATCCATGAGACGCTCCGTCACACCCGCGG
AGACAAGACGCTGGCCGCACGGCTGCTGGGCATCGCTGCGCGGACCATCTACCGCAAGCTGGAGCGCGAGCAGTCCACCG
GGGATGGCCCCACCGCCGCGCCCCCTGGCCCCGACACCGACGACTGA

Upstream 100 bases:

>100_bases
AGGTGCGGCGCGAGGACATTGGCCGGATGGGCGGCGGGCCGCTGGAGCCGGACGAGGAATCCGCTTAAGGGAACACGATT
TGCAGGAGGTTGCGCCCAAC

Downstream 100 bases:

>100_bases
CAGGGCGTCACACGGCCCCCCGCCTGCTTTTGACAATTTGTCTGGCGGGGTTTCGGAAGGCCCGTCACGCGTCAGGGGCG
CCTGCTATTCCGGAATAATT

Product: sigma-54 dependent DNA-binding response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 468; Mature: 467

Protein sequence:

>468_residues
MTSPTVLVVDDDRANLDSVIRIFQREGMATLAAANGTEALELLRRPEVAAMVTDLMMPNMDGQELLRAARAIRPDVEVVL
MTAYGTVETAVAAMKDGAYDFITKPLKRHALVKAIQKALEKRALVAENQSLKAKLAEMNAAGGRSMVGQSPAFRAMLDTI
RQAAPSTATVLLLGESGTGKELAARSVHEFSQRVRGPFVAVNCGALPENILEAELFGVERGAFTGAVARREGRFERAHGG
TLFLDEVGEMPLPAQVKLLRALAEGEIERLGGTQTVKVDVRLVAATNKDLQKEVAEGRFREDLYYRLNVVEIRVPALASR
REDIPLLADAFLRRFAAKNGKVLRGFSQEAMGVLENYAWPGNVRELEHAVERAVVLARGEVLDASDLPESVRKGPLGSAG
QLVIPIGTPMEEIERRVIHETLRHTRGDKTLAARLLGIAARTIYRKLEREQSTGDGPTAAPPGPDTDD

Sequences:

>Translated_468_residues
MTSPTVLVVDDDRANLDSVIRIFQREGMATLAAANGTEALELLRRPEVAAMVTDLMMPNMDGQELLRAARAIRPDVEVVL
MTAYGTVETAVAAMKDGAYDFITKPLKRHALVKAIQKALEKRALVAENQSLKAKLAEMNAAGGRSMVGQSPAFRAMLDTI
RQAAPSTATVLLLGESGTGKELAARSVHEFSQRVRGPFVAVNCGALPENILEAELFGVERGAFTGAVARREGRFERAHGG
TLFLDEVGEMPLPAQVKLLRALAEGEIERLGGTQTVKVDVRLVAATNKDLQKEVAEGRFREDLYYRLNVVEIRVPALASR
REDIPLLADAFLRRFAAKNGKVLRGFSQEAMGVLENYAWPGNVRELEHAVERAVVLARGEVLDASDLPESVRKGPLGSAG
QLVIPIGTPMEEIERRVIHETLRHTRGDKTLAARLLGIAARTIYRKLEREQSTGDGPTAAPPGPDTDD
>Mature_467_residues
TSPTVLVVDDDRANLDSVIRIFQREGMATLAAANGTEALELLRRPEVAAMVTDLMMPNMDGQELLRAARAIRPDVEVVLM
TAYGTVETAVAAMKDGAYDFITKPLKRHALVKAIQKALEKRALVAENQSLKAKLAEMNAAGGRSMVGQSPAFRAMLDTIR
QAAPSTATVLLLGESGTGKELAARSVHEFSQRVRGPFVAVNCGALPENILEAELFGVERGAFTGAVARREGRFERAHGGT
LFLDEVGEMPLPAQVKLLRALAEGEIERLGGTQTVKVDVRLVAATNKDLQKEVAEGRFREDLYYRLNVVEIRVPALASRR
EDIPLLADAFLRRFAAKNGKVLRGFSQEAMGVLENYAWPGNVRELEHAVERAVVLARGEVLDASDLPESVRKGPLGSAGQ
LVIPIGTPMEEIERRVIHETLRHTRGDKTLAARLLGIAARTIYRKLEREQSTGDGPTAAPPGPDTDD

Specific function: Member of the two-component regulatory system zraS/zraR. When activated by zraS it acts in conjunction with sigma-54 to regulate the expression of zraP. Positively autoregulates the expression of the zraSR operon [H]

COG id: COG2204

COG function: function code T; Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1790437, Length=449, Percent_Identity=48.3296213808463, Blast_Score=393, Evalue=1e-110,
Organism=Escherichia coli, GI1788550, Length=455, Percent_Identity=45.0549450549451, Blast_Score=377, Evalue=1e-106,
Organism=Escherichia coli, GI1788905, Length=446, Percent_Identity=41.4798206278027, Blast_Score=337, Evalue=1e-93,
Organism=Escherichia coli, GI1790299, Length=470, Percent_Identity=38.5106382978723, Blast_Score=319, Evalue=3e-88,
Organism=Escherichia coli, GI1789087, Length=330, Percent_Identity=47.2727272727273, Blast_Score=271, Evalue=9e-74,
Organism=Escherichia coli, GI87082117, Length=343, Percent_Identity=43.4402332361516, Blast_Score=263, Evalue=1e-71,
Organism=Escherichia coli, GI1789233, Length=322, Percent_Identity=41.9254658385093, Blast_Score=251, Evalue=1e-67,
Organism=Escherichia coli, GI1786524, Length=325, Percent_Identity=44.9230769230769, Blast_Score=238, Evalue=4e-64,
Organism=Escherichia coli, GI87082152, Length=313, Percent_Identity=42.8115015974441, Blast_Score=235, Evalue=6e-63,
Organism=Escherichia coli, GI87081872, Length=231, Percent_Identity=48.4848484848485, Blast_Score=218, Evalue=5e-58,
Organism=Escherichia coli, GI1787583, Length=320, Percent_Identity=36.5625, Blast_Score=187, Evalue=2e-48,
Organism=Escherichia coli, GI87081858, Length=301, Percent_Identity=33.2225913621262, Blast_Score=153, Evalue=3e-38,
Organism=Escherichia coli, GI1789828, Length=239, Percent_Identity=39.7489539748954, Blast_Score=150, Evalue=2e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR011006
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02954 HTH_8; PF00072 Response_reg; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 50848; Mature: 50717

Theoretical pI: Translated: 6.82; Mature: 6.82

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00676 SIGMA54_INTERACT_2 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSPTVLVVDDDRANLDSVIRIFQREGMATLAAANGTEALELLRRPEVAAMVTDLMMPNM
CCCCEEEEEECCCCCHHHHHHHHHHCCCEEEEECCCHHHHHHHHCCHHHHHHHHHHCCCC
DGQELLRAARAIRPDVEVVLMTAYGTVETAVAAMKDGAYDFITKPLKRHALVKAIQKALE
CHHHHHHHHHHCCCCCEEEEEEECCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
KRALVAENQSLKAKLAEMNAAGGRSMVGQSPAFRAMLDTIRQAAPSTATVLLLGESGTGK
HHHHHHCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEEEECCCCCH
ELAARSVHEFSQRVRGPFVAVNCGALPENILEAELFGVERGAFTGAVARREGRFERAHGG
HHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCC
TLFLDEVGEMPLPAQVKLLRALAEGEIERLGGTQTVKVDVRLVAATNKDLQKEVAEGRFR
EEEEHHCCCCCCCHHHHHHHHHHHCHHHHCCCCEEEEEEEEEEEECCHHHHHHHHCCHHH
EDLYYRLNVVEIRVPALASRREDIPLLADAFLRRFAAKNGKVLRGFSQEAMGVLENYAWP
HHHHEEEEEEEEECCHHHCCCCCCCHHHHHHHHHHHHCCCCEEECCCHHHHHHHHHCCCC
GNVRELEHAVERAVVLARGEVLDASDLPESVRKGPLGSAGQLVIPIGTPMEEIERRVIHE
CCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHCCCCCCCCEEEEECCCCHHHHHHHHHHH
TLRHTRGDKTLAARLLGIAARTIYRKLEREQSTGDGPTAAPPGPDTDD
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TSPTVLVVDDDRANLDSVIRIFQREGMATLAAANGTEALELLRRPEVAAMVTDLMMPNM
CCCEEEEEECCCCCHHHHHHHHHHCCCEEEEECCCHHHHHHHHCCHHHHHHHHHHCCCC
DGQELLRAARAIRPDVEVVLMTAYGTVETAVAAMKDGAYDFITKPLKRHALVKAIQKALE
CHHHHHHHHHHCCCCCEEEEEEECCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
KRALVAENQSLKAKLAEMNAAGGRSMVGQSPAFRAMLDTIRQAAPSTATVLLLGESGTGK
HHHHHHCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEEEECCCCCH
ELAARSVHEFSQRVRGPFVAVNCGALPENILEAELFGVERGAFTGAVARREGRFERAHGG
HHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCC
TLFLDEVGEMPLPAQVKLLRALAEGEIERLGGTQTVKVDVRLVAATNKDLQKEVAEGRFR
EEEEHHCCCCCCCHHHHHHHHHHHCHHHHCCCCEEEEEEEEEEEECCHHHHHHHHCCHHH
EDLYYRLNVVEIRVPALASRREDIPLLADAFLRRFAAKNGKVLRGFSQEAMGVLENYAWP
HHHHEEEEEEEEECCHHHCCCCCCCHHHHHHHHHHHHCCCCEEECCCHHHHHHHHHCCCC
GNVRELEHAVERAVVLARGEVLDASDLPESVRKGPLGSAGQLVIPIGTPMEEIERRVIHE
CCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHCCCCCCCCEEEEECCCCHHHHHHHHHHH
TLRHTRGDKTLAARLLGIAARTIYRKLEREQSTGDGPTAAPPGPDTDD
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]