Click here to switch to the map view.

The map label for this gene is obgE

Identifier: 108759348

GI number: 108759348

Start: 1731063

End: 1732520

Strand: Direct

Name: obgE

Synonym: MXAN_1471

Alternate gene names: 108759348

Gene position: 1731063-1732520 (Clockwise)

Preceding gene: 108758533

Following gene: 108758120

Centisome position: 18.94

GC content: 69.55

Gene sequence:

>1458_bases
ATGAAGTTCGTCGACGAGGTCCGCATCTTCGTGAAGGCGGGGGATGGCGGCAACGGCGCCGTCTCGTTCCGGCGGGAGAA
GTACATCGAGCGCGGTGGCCCCAATGGCGGGGACGGCGGTAACGGCGGCTCCGTCGTCTTCGTGGCGGATCCGCAGCTCA
CCACGCTGCTCGACTACCGCTACCAGCAGCACCACCGCGCCAGGAATGGCGAGCACGGCATGGGCAGCGACTGTAACGGT
CGCGCCGCCGAGGACATGGTGCTCAAGGTGCCCGTGGGCACGCTGGTGAAGGATGCCAACACCGGAGAGCTGCTGGTGGA
CCTCAGCGAGGCCGGCCAGCGCTGGGTGGCGGCGAAGGGCGGACGGGGCGGCCTGGGCAACATGAACTTCGCCACTTCCA
CCCGGCAGACGCCGCGCTTCGCCCAGGATGGGACGAAGGGCGAGGAGTTGACGCTCCGGCTGGAGCTGAAGCTGCTGGCG
GACGTGGGCCTGCTGGGCTTCCCCAACGCGGGCAAGAGCACGTTCATCTCCCGCGTGAGCCGGGCGCGGCCGAAGGTCGC
CGACTATCCCTTCACCACGCTGGTCCCCAACCTGGGCATGGTCCAGTACAAGGACGGCCTGTCCTTCGTGATGGCGGACA
TCCCCGGCATCATCGAGGGCGCCAGCGAGGGCGTGGGCCTGGGGCACCAGTTCCTGCGCCACGTGGAGCGGTGCAAGGTG
CTGATCCACCTCATCGACATGGGGGCGGAGGGCGAGGGCCGCGCGCCGCTGCACGACTTCGACGTGCTCAACGCGGAGCT
GGGCAAGTACAGCCCGGAGCTGGCGTCCAAGCCGCAGGTGGTGGCGGCCAACAAGTTGGATCTGCCCGACGCGCAGGCCC
GGCTGGAGGGCTTCACGGAGGCGCTGCGTGAACGCGGCATCCGTGTGTATCCCGTGTCCTGCGCCACCGGCGAGGGCATG
CAGCCGCTGATGGACTCCGTGGCGGAGGTGCTGTTCACGGGGCGCACCGAGAAGCTCCACGTGGAGATTCCCGCCAAGGC
GGCTCGGGCGGGGAAGGCCAAGACGAAGGCCGCGGAGAAGAAGGCTCTGGCTCGCAATGCGGGCGCAGCTGCGGCGACGA
AGTCTGCGACGAAGAAGTCTGCGGCTGCGAAGAAGGCCGTGACGAAGAAGGCTCCGGCGCGGAAGGCGGGTGCAGTGGCG
AAGACGTCCGCAGCGCGCAAGGCAGGCACTGCTGCGGCGAAGAAGGCCCCGGCTCGCAAGTCGGGCACCGCGCCCGTGAA
GAAGGCCGCGGCGAAGAAGGCCCCAGCTCGCAAGTCGGGCACCGCGCCCGCGAAGAAGTCCGCCGTGAAGAAGGCATCCG
CGCGCAAGAGCGGCTCGTCGGGCAAGGCCGCCGCGAAGAAGGCATCCGCGGCCACGAAGCGCGCTCCGGCGCGCAAGTCG
GGCGGCGGGAGGAGCTGA

Upstream 100 bases:

>100_bases
ACCGTGCGGCACCCACGAGCGGGTCGCTTCTCCAGTCCACGCGCCCTTCCGGCAGCGGGATGCGAGGGCGGCCCGCTTTT
TGTTTATCCAGGAGTCCCAG

Downstream 100 bases:

>100_bases
GTCCATGTCGGGTGGTGGTGCGCGCTACGAGCGCTATGAGCGGGAGCAGTTCGAGCCGGAGCAGTTCCTGCTCGACGTGC
GCAAGGAGAAGATTGATCGC

Product: GTPase ObgE

Products: NA

Alternate protein names: GTP-binding protein obg

Number of amino acids: Translated: 485; Mature: 485

Protein sequence:

>485_residues
MKFVDEVRIFVKAGDGGNGAVSFRREKYIERGGPNGGDGGNGGSVVFVADPQLTTLLDYRYQQHHRARNGEHGMGSDCNG
RAAEDMVLKVPVGTLVKDANTGELLVDLSEAGQRWVAAKGGRGGLGNMNFATSTRQTPRFAQDGTKGEELTLRLELKLLA
DVGLLGFPNAGKSTFISRVSRARPKVADYPFTTLVPNLGMVQYKDGLSFVMADIPGIIEGASEGVGLGHQFLRHVERCKV
LIHLIDMGAEGEGRAPLHDFDVLNAELGKYSPELASKPQVVAANKLDLPDAQARLEGFTEALRERGIRVYPVSCATGEGM
QPLMDSVAEVLFTGRTEKLHVEIPAKAARAGKAKTKAAEKKALARNAGAAAATKSATKKSAAAKKAVTKKAPARKAGAVA
KTSAARKAGTAAAKKAPARKSGTAPVKKAAAKKAPARKSGTAPAKKSAVKKASARKSGSSGKAAAKKASAATKRAPARKS
GGGRS

Sequences:

>Translated_485_residues
MKFVDEVRIFVKAGDGGNGAVSFRREKYIERGGPNGGDGGNGGSVVFVADPQLTTLLDYRYQQHHRARNGEHGMGSDCNG
RAAEDMVLKVPVGTLVKDANTGELLVDLSEAGQRWVAAKGGRGGLGNMNFATSTRQTPRFAQDGTKGEELTLRLELKLLA
DVGLLGFPNAGKSTFISRVSRARPKVADYPFTTLVPNLGMVQYKDGLSFVMADIPGIIEGASEGVGLGHQFLRHVERCKV
LIHLIDMGAEGEGRAPLHDFDVLNAELGKYSPELASKPQVVAANKLDLPDAQARLEGFTEALRERGIRVYPVSCATGEGM
QPLMDSVAEVLFTGRTEKLHVEIPAKAARAGKAKTKAAEKKALARNAGAAAATKSATKKSAAAKKAVTKKAPARKAGAVA
KTSAARKAGTAAAKKAPARKSGTAPVKKAAAKKAPARKSGTAPAKKSAVKKASARKSGSSGKAAAKKASAATKRAPARKS
GGGRS
>Mature_485_residues
MKFVDEVRIFVKAGDGGNGAVSFRREKYIERGGPNGGDGGNGGSVVFVADPQLTTLLDYRYQQHHRARNGEHGMGSDCNG
RAAEDMVLKVPVGTLVKDANTGELLVDLSEAGQRWVAAKGGRGGLGNMNFATSTRQTPRFAQDGTKGEELTLRLELKLLA
DVGLLGFPNAGKSTFISRVSRARPKVADYPFTTLVPNLGMVQYKDGLSFVMADIPGIIEGASEGVGLGHQFLRHVERCKV
LIHLIDMGAEGEGRAPLHDFDVLNAELGKYSPELASKPQVVAANKLDLPDAQARLEGFTEALRERGIRVYPVSCATGEGM
QPLMDSVAEVLFTGRTEKLHVEIPAKAARAGKAKTKAAEKKALARNAGAAAATKSATKKSAAAKKAVTKKAPARKAGAVA
KTSAARKAGTAAAKKAPARKSGTAPVKKAAAKKAPARKSGTAPAKKSAVKKASARKSGSSGKAAAKKASAATKRAPARKS
GGGRS

Specific function: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in t

COG id: COG0536

COG function: function code R; Predicted GTPase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain

Homologues:

Organism=Homo sapiens, GI24308117, Length=337, Percent_Identity=42.7299703264095, Blast_Score=209, Evalue=5e-54,
Organism=Homo sapiens, GI111955139, Length=355, Percent_Identity=34.9295774647887, Blast_Score=182, Evalue=4e-46,
Organism=Homo sapiens, GI111955063, Length=188, Percent_Identity=37.7659574468085, Blast_Score=137, Evalue=2e-32,
Organism=Homo sapiens, GI4557537, Length=122, Percent_Identity=36.8852459016393, Blast_Score=76, Evalue=8e-14,
Organism=Homo sapiens, GI4758796, Length=128, Percent_Identity=35.15625, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI58761500, Length=128, Percent_Identity=30.46875, Blast_Score=67, Evalue=3e-11,
Organism=Escherichia coli, GI1789574, Length=335, Percent_Identity=53.134328358209, Blast_Score=305, Evalue=6e-84,
Organism=Escherichia coli, GI1787454, Length=130, Percent_Identity=32.3076923076923, Blast_Score=69, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI17508313, Length=332, Percent_Identity=39.1566265060241, Blast_Score=181, Evalue=8e-46,
Organism=Caenorhabditis elegans, GI17552324, Length=309, Percent_Identity=32.6860841423948, Blast_Score=150, Evalue=1e-36,
Organism=Caenorhabditis elegans, GI17509631, Length=128, Percent_Identity=35.15625, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17555344, Length=119, Percent_Identity=34.453781512605, Blast_Score=68, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI71981008, Length=128, Percent_Identity=32.03125, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI25145600, Length=184, Percent_Identity=28.804347826087, Blast_Score=66, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI25145602, Length=184, Percent_Identity=29.3478260869565, Blast_Score=66, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6321962, Length=179, Percent_Identity=40.7821229050279, Blast_Score=134, Evalue=3e-32,
Organism=Saccharomyces cerevisiae, GI6319281, Length=109, Percent_Identity=38.5321100917431, Blast_Score=77, Evalue=5e-15,
Organism=Saccharomyces cerevisiae, GI6321612, Length=119, Percent_Identity=31.0924369747899, Blast_Score=64, Evalue=6e-11,
Organism=Drosophila melanogaster, GI20129375, Length=329, Percent_Identity=42.5531914893617, Blast_Score=208, Evalue=6e-54,
Organism=Drosophila melanogaster, GI24585318, Length=296, Percent_Identity=38.8513513513513, Blast_Score=166, Evalue=5e-41,
Organism=Drosophila melanogaster, GI24640873, Length=129, Percent_Identity=32.5581395348837, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24640877, Length=129, Percent_Identity=32.5581395348837, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24640875, Length=129, Percent_Identity=32.5581395348837, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI17981711, Length=119, Percent_Identity=35.2941176470588, Blast_Score=69, Evalue=7e-12,
Organism=Drosophila melanogaster, GI21356473, Length=119, Percent_Identity=32.7731092436975, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): OBG_MYXXD (Q1DC95)

Other databases:

- EMBL:   CP000113
- RefSeq:   YP_629728.1
- ProteinModelPortal:   Q1DC95
- SMR:   Q1DC95
- STRING:   Q1DC95
- GeneID:   4103039
- GenomeReviews:   CP000113_GR
- KEGG:   mxa:MXAN_1471
- TIGR:   MXAN_1471
- eggNOG:   COG0536
- HOGENOM:   HBG716038
- OMA:   VIDCASE
- PhylomeDB:   Q1DC95
- ProtClustDB:   PRK12296
- BioCyc:   MXAN246197:MXAN_1471-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01454
- InterPro:   IPR014100
- InterPro:   IPR006074
- InterPro:   IPR006073
- InterPro:   IPR006169
- InterPro:   IPR002917
- InterPro:   IPR005225
- Gene3D:   G3DSA:2.70.210.12
- PANTHER:   PTHR11702:SF3
- PRINTS:   PR00326
- TIGRFAMs:   TIGR02729
- TIGRFAMs:   TIGR00231

Pfam domain/function: PF01018 GTP1_OBG; PF01926 MMR_HSR1; SSF82051 GTP1_OBG_sub

EC number: NA

Molecular weight: Translated: 50609; Mature: 50609

Theoretical pI: Translated: 10.91; Mature: 10.91

Prosite motif: PS00905 GTP1_OBG

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFVDEVRIFVKAGDGGNGAVSFRREKYIERGGPNGGDGGNGGSVVFVADPQLTTLLDYR
CCCHHEEEEEEEECCCCCCCCHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCHHHHHHHH
YQQHHRARNGEHGMGSDCNGRAAEDMVLKVPVGTLVKDANTGELLVDLSEAGQRWVAAKG
HHHHHHHCCCCCCCCCCCCCCCCCCEEEEECHHHHHCCCCCCCEEEEHHHCCCEEEEECC
GRGGLGNMNFATSTRQTPRFAQDGTKGEELTLRLELKLLADVGLLGFPNAGKSTFISRVS
CCCCCCCCCCCCCCCCCCCHHCCCCCCCEEEEEEEEEEHHCCCCCCCCCCCHHHHHHHHH
RARPKVADYPFTTLVPNLGMVQYKDGLSFVMADIPGIIEGASEGVGLGHQFLRHVERCKV
HCCCCCCCCCHHHHCCCCCCEEECCCCHHHHHHCCHHHHCCCCCCCHHHHHHHHHHHHHH
LIHLIDMGAEGEGRAPLHDFDVLNAELGKYSPELASKPQVVAANKLDLPDAQARLEGFTE
HHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCHHHCCCCCEEECCCCCCCHHHHHHHHHHH
ALRERGIRVYPVSCATGEGMQPLMDSVAEVLFTGRTEKLHVEIPAKAARAGKAKTKAAEK
HHHHCCCEEEEECCCCCCCHHHHHHHHHHHHHCCCCCEEEEECCHHHHHCCCHHHHHHHH
KALARNAGAAAATKSATKKSAAAKKAVTKKAPARKAGAVAKTSAARKAGTAAAKKAPARK
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHCCHHHHHHHHHHHHHHHHCCCCCC
SGTAPVKKAAAKKAPARKSGTAPAKKSAVKKASARKSGSSGKAAAKKASAATKRAPARKS
CCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCC
GGGRS
CCCCC
>Mature Secondary Structure
MKFVDEVRIFVKAGDGGNGAVSFRREKYIERGGPNGGDGGNGGSVVFVADPQLTTLLDYR
CCCHHEEEEEEEECCCCCCCCHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCHHHHHHHH
YQQHHRARNGEHGMGSDCNGRAAEDMVLKVPVGTLVKDANTGELLVDLSEAGQRWVAAKG
HHHHHHHCCCCCCCCCCCCCCCCCCEEEEECHHHHHCCCCCCCEEEEHHHCCCEEEEECC
GRGGLGNMNFATSTRQTPRFAQDGTKGEELTLRLELKLLADVGLLGFPNAGKSTFISRVS
CCCCCCCCCCCCCCCCCCCHHCCCCCCCEEEEEEEEEEHHCCCCCCCCCCCHHHHHHHHH
RARPKVADYPFTTLVPNLGMVQYKDGLSFVMADIPGIIEGASEGVGLGHQFLRHVERCKV
HCCCCCCCCCHHHHCCCCCCEEECCCCHHHHHHCCHHHHCCCCCCCHHHHHHHHHHHHHH
LIHLIDMGAEGEGRAPLHDFDVLNAELGKYSPELASKPQVVAANKLDLPDAQARLEGFTE
HHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCHHHCCCCCEEECCCCCCCHHHHHHHHHHH
ALRERGIRVYPVSCATGEGMQPLMDSVAEVLFTGRTEKLHVEIPAKAARAGKAKTKAAEK
HHHHCCCEEEEECCCCCCCHHHHHHHHHHHHHCCCCCEEEEECCHHHHHCCCHHHHHHHH
KALARNAGAAAATKSATKKSAAAKKAVTKKAPARKAGAVAKTSAARKAGTAAAKKAPARK
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHCCHHHHHHHHHHHHHHHHCCCCCC
SGTAPVKKAAAKKAPARKSGTAPAKKSAVKKASARKSGSSGKAAAKKASAATKRAPARKS
CCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCC
GGGRS
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA