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The map label for this gene is trpE [H]

Identifier: 108759288

GI number: 108759288

Start: 1864854

End: 1866308

Strand: Reverse

Name: trpE [H]

Synonym: MXAN_1590

Alternate gene names: 108759288

Gene position: 1866308-1864854 (Counterclockwise)

Preceding gene: 108760022

Following gene: 108760703

Centisome position: 20.42

GC content: 67.63

Gene sequence:

>1455_bases
ATGAGCCGCCCGCCCTCCCCCACGCGCTTCCCGGACCGGACGTCCTTCGAGACGTTCGTGGCCCAGGGCTACAACCAGGT
GCCCGTGGTGCGGCGGCTCCCGCTCGGGGCGCTGCGTCCCGTGGACCTCCTGCGAGCCCTCCCAGCGGAAAGCCGGTTCC
TGCTGGAGAGCACCCGGGTCAGCGCCGAGGGGCGCTATTCGTTCCTCGGCGCGAAGCCCTTCCTGCGTTTCACCGCGAAA
GAGGGACAGTGCTTCATTGATGGCGCGCTCCAGCAGGGTACGCCGCAGGAGGTGCTGCGCTCGCTGCTGCGCCGGTGGCG
TGGCGTGCGTCATCCCGGAATGCCGCTCTTCTGCGGCGGCGCGGTGGGCTTCTTCGGCTACGAGGCCGCGCACTGTTTCG
AGTCCCTGCCCCGGCACCCACGGGACGACCTGCACCTGCCCGAAATCGACCTGTCATTCATCGACACCTTCCTGACGGTG
GACCACCACGAGGGCCAATTGCTCCTGGTGGCCACGGGCTCGGACTGGGAGGACTGTGAGCGCAGGTTGGACGCGTTGGA
GGTCCACGTCCGCACCGCGACGCCCACGGCGCCACGCGTGCCACCCGCGATGGATGGGCCCACCTCGGCGTATCGCTCCA
ACTTCACCCTCGATGCTTACCTGGACGCAGTCGAGCGCGTGCGCGAGTACATCCGCGCCGGTGACACGTATCAGGTCAAT
CTCTCGCAGCGGCTGGAGGTGGACTTTCCCGGTGAGCCGCTCGCGCTCTACGAGACGCTGTCCGCCATCAACCCCGTCCA
CTTCGCCAGCTATCTCGAAGGTGACGGCTTCCACGTCGTCAGCGCCTCACCGGAGCGGCTGGTGCGTGTGGAGAACGGCC
GAGCCACCACGCGGCCCATCGCCGGAACGCGCCGACGGGGCACGCCCGAAGAGGAAGCGCGCTTCGTCCACGAGCTGCGC
ACCAACGAGAAGGAGCGCGCCGAGCACGCCATGCTGGTGGACCTGGAGCGCAACGACCTGGGCCGGGTGTGCACCTATGG
CTCGGTCGAGGTGACGAAGCTGATGGACATCGTCGAGTACGCCCACGTCCTCCACATTGAATCGGAGGTCGTCGGCCAGC
TCGCGCCGGGCGTGGAGCCGCTGGACGTGGTGGGCGCGCTCTTCCCAGGCGGGACGATTACGGGCGTGCCGAAGATACGC
ACGATGCAAATCATCACCGAGCTGGAGCCACATGCGCGCGGGCTCTATACGGGCTCGCTGGGGTACCTGTCCTTCACGGG
TGATTTGGATTTGAACATCGTCATCCGCACGCTGGTGGTGAAGGACGGCCAGGCCTACGCGCAGGTGGGAGGCGGCATCG
TCCACGACTCGCAGCCCCGACAGGAATACAAGGAGACGCTCAACAAGGCGCGCTCGCAGCTCCTGGCCCTGGCATCGGTG
GGGAGGCCGGGATGA

Upstream 100 bases:

>100_bases
CGCTGACCGCACGGAACGTTCATTCCACCGGCCCCCCCTGCCCGGGGGGCCATGGACGACTCGAACTGGACGGAACGTTC
CTGGTATCAAGCGCCTCGAC

Downstream 100 bases:

>100_bases
TTCTCGTCATCGACAACTTCGATTCCTTCACCTTCAACCTCGTGCAGGCGCTGGGTGCCCAGGGCGCCGAGCTGAAGGTG
GTGCGCAATGACGCCATCAC

Product: putative para-aminobenzoate synthase, component I

Products: NA

Alternate protein names: Anthranilate synthase component I [H]

Number of amino acids: Translated: 484; Mature: 483

Protein sequence:

>484_residues
MSRPPSPTRFPDRTSFETFVAQGYNQVPVVRRLPLGALRPVDLLRALPAESRFLLESTRVSAEGRYSFLGAKPFLRFTAK
EGQCFIDGALQQGTPQEVLRSLLRRWRGVRHPGMPLFCGGAVGFFGYEAAHCFESLPRHPRDDLHLPEIDLSFIDTFLTV
DHHEGQLLLVATGSDWEDCERRLDALEVHVRTATPTAPRVPPAMDGPTSAYRSNFTLDAYLDAVERVREYIRAGDTYQVN
LSQRLEVDFPGEPLALYETLSAINPVHFASYLEGDGFHVVSASPERLVRVENGRATTRPIAGTRRRGTPEEEARFVHELR
TNEKERAEHAMLVDLERNDLGRVCTYGSVEVTKLMDIVEYAHVLHIESEVVGQLAPGVEPLDVVGALFPGGTITGVPKIR
TMQIITELEPHARGLYTGSLGYLSFTGDLDLNIVIRTLVVKDGQAYAQVGGGIVHDSQPRQEYKETLNKARSQLLALASV
GRPG

Sequences:

>Translated_484_residues
MSRPPSPTRFPDRTSFETFVAQGYNQVPVVRRLPLGALRPVDLLRALPAESRFLLESTRVSAEGRYSFLGAKPFLRFTAK
EGQCFIDGALQQGTPQEVLRSLLRRWRGVRHPGMPLFCGGAVGFFGYEAAHCFESLPRHPRDDLHLPEIDLSFIDTFLTV
DHHEGQLLLVATGSDWEDCERRLDALEVHVRTATPTAPRVPPAMDGPTSAYRSNFTLDAYLDAVERVREYIRAGDTYQVN
LSQRLEVDFPGEPLALYETLSAINPVHFASYLEGDGFHVVSASPERLVRVENGRATTRPIAGTRRRGTPEEEARFVHELR
TNEKERAEHAMLVDLERNDLGRVCTYGSVEVTKLMDIVEYAHVLHIESEVVGQLAPGVEPLDVVGALFPGGTITGVPKIR
TMQIITELEPHARGLYTGSLGYLSFTGDLDLNIVIRTLVVKDGQAYAQVGGGIVHDSQPRQEYKETLNKARSQLLALASV
GRPG
>Mature_483_residues
SRPPSPTRFPDRTSFETFVAQGYNQVPVVRRLPLGALRPVDLLRALPAESRFLLESTRVSAEGRYSFLGAKPFLRFTAKE
GQCFIDGALQQGTPQEVLRSLLRRWRGVRHPGMPLFCGGAVGFFGYEAAHCFESLPRHPRDDLHLPEIDLSFIDTFLTVD
HHEGQLLLVATGSDWEDCERRLDALEVHVRTATPTAPRVPPAMDGPTSAYRSNFTLDAYLDAVERVREYIRAGDTYQVNL
SQRLEVDFPGEPLALYETLSAINPVHFASYLEGDGFHVVSASPERLVRVENGRATTRPIAGTRRRGTPEEEARFVHELRT
NEKERAEHAMLVDLERNDLGRVCTYGSVEVTKLMDIVEYAHVLHIESEVVGQLAPGVEPLDVVGALFPGGTITGVPKIRT
MQIITELEPHARGLYTGSLGYLSFTGDLDLNIVIRTLVVKDGQAYAQVGGGIVHDSQPRQEYKETLNKARSQLLALASVG
RPG

Specific function: Catalyzes The Biosynthesis Of 4-Amino-4-Deoxychorismate (Adc) From Chorismate And Glutamine. [C]

COG id: COG0147

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component I

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate synthase component I family [H]

Homologues:

Organism=Escherichia coli, GI1788114, Length=422, Percent_Identity=36.2559241706161, Blast_Score=258, Evalue=5e-70,
Organism=Escherichia coli, GI1787518, Length=374, Percent_Identity=36.096256684492, Blast_Score=206, Evalue=2e-54,
Organism=Escherichia coli, GI1786809, Length=221, Percent_Identity=28.5067873303167, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI87082077, Length=215, Percent_Identity=26.5116279069767, Blast_Score=67, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6320935, Length=485, Percent_Identity=34.8453608247423, Blast_Score=246, Evalue=4e-66,
Organism=Saccharomyces cerevisiae, GI6324361, Length=402, Percent_Identity=27.1144278606965, Blast_Score=124, Evalue=3e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005801
- InterPro:   IPR019999
- InterPro:   IPR006805
- InterPro:   IPR005256
- InterPro:   IPR015890 [H]

Pfam domain/function: PF04715 Anth_synt_I_N; PF00425 Chorismate_bind [H]

EC number: =4.1.3.27 [H]

Molecular weight: Translated: 53732; Mature: 53600

Theoretical pI: Translated: 6.24; Mature: 6.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRPPSPTRFPDRTSFETFVAQGYNQVPVVRRLPLGALRPVDLLRALPAESRFLLESTRV
CCCCCCCCCCCCCCCHHHHHHCCCCCCCHHHHCCCCCCCHHHHHHHCCCCCHHHHHHHCC
SAEGRYSFLGAKPFLRFTAKEGQCFIDGALQQGTPQEVLRSLLRRWRGVRHPGMPLFCGG
CCCCCEEEECCCCEEEEECCCCCEEEECCCCCCCHHHHHHHHHHHHHCCCCCCCCEEECC
AVGFFGYEAAHCFESLPRHPRDDLHLPEIDLSFIDTFLTVDHHEGQLLLVATGSDWEDCE
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHEEECCCCEEEEEECCCCHHHHH
RRLDALEVHVRTATPTAPRVPPAMDGPTSAYRSNFTLDAYLDAVERVREYIRAGDTYQVN
HHHHHHEEEEEECCCCCCCCCCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHCCCEEEEE
LSQRLEVDFPGEPLALYETLSAINPVHFASYLEGDGFHVVSASPERLVRVENGRATTRPI
CCCEEEECCCCCCHHHHHHHHHCCHHHHHHHHCCCCEEEEECCHHHEEEECCCCCCCCCC
AGTRRRGTPEEEARFVHELRTNEKERAEHAMLVDLERNDLGRVCTYGSVEVTKLMDIVEY
CCCCCCCCCHHHHHHHHHHHCCHHHHCCCEEEEEECCCCCCCEECCCCCHHHHHHHHHHH
AHVLHIESEVVGQLAPGVEPLDVVGALFPGGTITGVPKIRTMQIITELEPHARGLYTGSL
HHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCHHHCEEEECCC
GYLSFTGDLDLNIVIRTLVVKDGQAYAQVGGGIVHDSQPRQEYKETLNKARSQLLALASV
EEEEEECCCCCEEEEEEEEECCCCHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHC
GRPG
CCCC
>Mature Secondary Structure 
SRPPSPTRFPDRTSFETFVAQGYNQVPVVRRLPLGALRPVDLLRALPAESRFLLESTRV
CCCCCCCCCCCCCCHHHHHHCCCCCCCHHHHCCCCCCCHHHHHHHCCCCCHHHHHHHCC
SAEGRYSFLGAKPFLRFTAKEGQCFIDGALQQGTPQEVLRSLLRRWRGVRHPGMPLFCGG
CCCCCEEEECCCCEEEEECCCCCEEEECCCCCCCHHHHHHHHHHHHHCCCCCCCCEEECC
AVGFFGYEAAHCFESLPRHPRDDLHLPEIDLSFIDTFLTVDHHEGQLLLVATGSDWEDCE
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHEEECCCCEEEEEECCCCHHHHH
RRLDALEVHVRTATPTAPRVPPAMDGPTSAYRSNFTLDAYLDAVERVREYIRAGDTYQVN
HHHHHHEEEEEECCCCCCCCCCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHCCCEEEEE
LSQRLEVDFPGEPLALYETLSAINPVHFASYLEGDGFHVVSASPERLVRVENGRATTRPI
CCCEEEECCCCCCHHHHHHHHHCCHHHHHHHHCCCCEEEEECCHHHEEEECCCCCCCCCC
AGTRRRGTPEEEARFVHELRTNEKERAEHAMLVDLERNDLGRVCTYGSVEVTKLMDIVEY
CCCCCCCCCHHHHHHHHHHHCCHHHHCCCEEEEEECCCCCCCEECCCCCHHHHHHHHHHH
AHVLHIESEVVGQLAPGVEPLDVVGALFPGGTITGVPKIRTMQIITELEPHARGLYTGSL
HHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCHHHCEEEECCC
GYLSFTGDLDLNIVIRTLVVKDGQAYAQVGGGIVHDSQPRQEYKETLNKARSQLLALASV
EEEEEECCCCCEEEEEEEEECCCCHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHC
GRPG
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2732211 [H]