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The map label for this gene is hutI

Identifier: 108759220

GI number: 108759220

Start: 5350285

End: 5351550

Strand: Direct

Name: hutI

Synonym: MXAN_4345

Alternate gene names: 108759220

Gene position: 5350285-5351550 (Clockwise)

Preceding gene: 108757377

Following gene: 108758393

Centisome position: 58.54

GC content: 69.67

Gene sequence:

>1266_bases
ATGGACGTGCTGGACCTGCTGGTGCGCAACACCTCCGAAGTGCTGACGGTGGAAGGCTCGCACCGCGAGCGCGCGGAGGA
CGCCCTCACCCCACGACCAGGTGCGGTTGTGGGTGTCCGTGAAGGACGCATCGCCTACGTGGGCCCCGAGGCCGGTCTCC
CCACGGGCGCGGTGGGCCCTGGCACCGAGGTGGTGGACGCCCAGGGTGGCTTCGTGGGCCCCGGCTTCGTGGACCCCCAC
ACGCACCTCGTCTTCGCCGGTGAGCGCTCCGCGGAGTTCGACCTGCGCAACCAGGGCGCCACCTACCTGGAGATTGCCAA
GGCGGGCGGTGGCATCGCCAGCACGGTGCAGGCAACGCGGGCCGCGAGCGAGGAGGAGCTGGTGCGGCTCGCCCTCCCCC
GCACGAAGCGCCTGTTGGAGCAGGGCGTCACAACGGCGGAGGTGAAGAGCGGCTACGGGCTCGACCTGGCGACGGAGCTG
AAGATGCTGCGCGCGGTGCGGCGGCTCGGAACGCTGACGCCGCTGGAGCTGGTCCCCACACTGCTGTGCGCGCACGCCGT
GCCGGAGGAGTACCGCGGCAAGCGCGAGGACTACGTGCGGCTGTGCATCGAGGAGATTCTTCCCGCCGTCGCGCGCGAGG
GGCTGGCGCGCTTCTGTGACGTTTTCGTGGAAGACAGCGCCTTCACCGTGGACGAGGCGCGCCGCATCTTGAGCGCGGGC
CGGGCACTGGGAATGGTGCCGCGGCTGCATGCAGACCAACTCACCGTGTGTGGTGCCTCCGAGCTCGCCGCGGAGCTGGG
GGCCGCCACGGCGGACCACCTGGAGCAGGTGACGGACGCGGGACTCAAGGCGCTGGCGGACGCCAACGTCACGGCGGTGC
TCGTTCCCACCTCCACGCTGTTCCTGCGCATGCGGCCCTACGCGCCTGGACGCCGCATCCGCGATGCGGGGCTCAACGTC
GCTTTGGGCACCAACGTCAACCCCGGTTCCGCCATGAGTGAAAACACAGCACTGGCGCTGGGACTTGCGTGTCTGGAAAA
CGGGCTTACTGCGGCAGAGGCGTATTGGGGAGCCACCCGTGGCGCGGCGATGTCCTTGGGGCTGCAACAGCACGGAAGGC
TGACCGTGGGTGACGCGGGCGACCTGGTGGTCTTCAGCTGTGCTTCGTACCGCCACCTGCCCTACCATCTAGGGGTAGCG
CACGCGCGAGTGGTCGTGAAGGCCGGACGCATCGCTGTCCGGCAGCAGATGGAAGGCTGCGCGTGA

Upstream 100 bases:

>100_bases
GAACGACTTCGAGCTGTCGGGCGGGTTCGGCCGCGCGAAGGTTGGCAAGGGTGTGAGCTGGAACGTGCCCATCATGGGCG
CACGCGGAGGACGTTGAGCC

Downstream 100 bases:

>100_bases
ACCGGCGTCGCAGAGACACAGCGGCTCCGAGTGGATAAAGACGGAACGACATCCGTCAGGGCCGGACGTTAAGAATATTC
GTTGCTAGCCATGTGCCGAC

Product: imidazolonepropionase

Products: NA

Alternate protein names: Imidazolone-5-propionate hydrolase

Number of amino acids: Translated: 421; Mature: 421

Protein sequence:

>421_residues
MDVLDLLVRNTSEVLTVEGSHRERAEDALTPRPGAVVGVREGRIAYVGPEAGLPTGAVGPGTEVVDAQGGFVGPGFVDPH
THLVFAGERSAEFDLRNQGATYLEIAKAGGGIASTVQATRAASEEELVRLALPRTKRLLEQGVTTAEVKSGYGLDLATEL
KMLRAVRRLGTLTPLELVPTLLCAHAVPEEYRGKREDYVRLCIEEILPAVAREGLARFCDVFVEDSAFTVDEARRILSAG
RALGMVPRLHADQLTVCGASELAAELGAATADHLEQVTDAGLKALADANVTAVLVPTSTLFLRMRPYAPGRRIRDAGLNV
ALGTNVNPGSAMSENTALALGLACLENGLTAAEAYWGATRGAAMSLGLQQHGRLTVGDAGDLVVFSCASYRHLPYHLGVA
HARVVVKAGRIAVRQQMEGCA

Sequences:

>Translated_421_residues
MDVLDLLVRNTSEVLTVEGSHRERAEDALTPRPGAVVGVREGRIAYVGPEAGLPTGAVGPGTEVVDAQGGFVGPGFVDPH
THLVFAGERSAEFDLRNQGATYLEIAKAGGGIASTVQATRAASEEELVRLALPRTKRLLEQGVTTAEVKSGYGLDLATEL
KMLRAVRRLGTLTPLELVPTLLCAHAVPEEYRGKREDYVRLCIEEILPAVAREGLARFCDVFVEDSAFTVDEARRILSAG
RALGMVPRLHADQLTVCGASELAAELGAATADHLEQVTDAGLKALADANVTAVLVPTSTLFLRMRPYAPGRRIRDAGLNV
ALGTNVNPGSAMSENTALALGLACLENGLTAAEAYWGATRGAAMSLGLQQHGRLTVGDAGDLVVFSCASYRHLPYHLGVA
HARVVVKAGRIAVRQQMEGCA
>Mature_421_residues
MDVLDLLVRNTSEVLTVEGSHRERAEDALTPRPGAVVGVREGRIAYVGPEAGLPTGAVGPGTEVVDAQGGFVGPGFVDPH
THLVFAGERSAEFDLRNQGATYLEIAKAGGGIASTVQATRAASEEELVRLALPRTKRLLEQGVTTAEVKSGYGLDLATEL
KMLRAVRRLGTLTPLELVPTLLCAHAVPEEYRGKREDYVRLCIEEILPAVAREGLARFCDVFVEDSAFTVDEARRILSAG
RALGMVPRLHADQLTVCGASELAAELGAATADHLEQVTDAGLKALADANVTAVLVPTSTLFLRMRPYAPGRRIRDAGLNV
ALGTNVNPGSAMSENTALALGLACLENGLTAAEAYWGATRGAAMSLGLQQHGRLTVGDAGDLVVFSCASYRHLPYHLGVA
HARVVVKAGRIAVRQQMEGCA

Specific function: Unknown

COG id: COG1228

COG function: function code Q; Imidazolonepropionase and related amidohydrolases

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hutI family

Homologues:

Organism=Homo sapiens, GI223972677, Length=426, Percent_Identity=37.793427230047, Blast_Score=230, Evalue=2e-60,
Organism=Caenorhabditis elegans, GI17555004, Length=399, Percent_Identity=35.0877192982456, Blast_Score=231, Evalue=5e-61,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HUTI_MYXXD (Q1D4A5)

Other databases:

- EMBL:   CP000113
- RefSeq:   YP_632518.1
- ProteinModelPortal:   Q1D4A5
- SMR:   Q1D4A5
- STRING:   Q1D4A5
- GeneID:   4101176
- GenomeReviews:   CP000113_GR
- KEGG:   mxa:MXAN_4345
- TIGR:   MXAN_4345
- eggNOG:   COG1228
- HOGENOM:   HBG686142
- OMA:   MNMACTL
- BioCyc:   MXAN246197:MXAN_4345-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00372
- InterPro:   IPR006680
- InterPro:   IPR005920
- InterPro:   IPR011059
- TIGRFAMs:   TIGR01224

Pfam domain/function: PF01979 Amidohydro_1; SSF51338 Metalo_hydrolase

EC number: =3.5.2.7

Molecular weight: Translated: 44455; Mature: 44455

Theoretical pI: Translated: 6.02; Mature: 6.02

Prosite motif: NA

Important sites: BINDING 89-89 BINDING 102-102 BINDING 152-152 BINDING 185-185 BINDING 253-253

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDVLDLLVRNTSEVLTVEGSHRERAEDALTPRPGAVVGVREGRIAYVGPEAGLPTGAVGP
CCHHHHHHCCCCCEEEEECCCHHHHHHCCCCCCCCEEEECCCEEEEECCCCCCCCCCCCC
GTEVVDAQGGFVGPGFVDPHTHLVFAGERSAEFDLRNQGATYLEIAKAGGGIASTVQATR
CCCEEECCCCEECCCCCCCCCEEEEECCCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHH
AASEEELVRLALPRTKRLLEQGVTTAEVKSGYGLDLATELKMLRAVRRLGTLTPLELVPT
CCCHHHHHHHHCHHHHHHHHHCCCEEHHCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHH
LLCAHAVPEEYRGKREDYVRLCIEEILPAVAREGLARFCDVFVEDSAFTVDEARRILSAG
HHHHHCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHC
RALGMVPRLHADQLTVCGASELAAELGAATADHLEQVTDAGLKALADANVTAVLVPTSTL
HHHCCCCCCCCCCEEECCHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCEEEEEEECCEE
FLRMRPYAPGRRIRDAGLNVALGTNVNPGSAMSENTALALGLACLENGLTAAEAYWGATR
EEEECCCCCCCCHHHCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHCCCC
GAAMSLGLQQHGRLTVGDAGDLVVFSCASYRHLPYHLGVAHARVVVKAGRIAVRQQMEGC
CHHHCCCHHHCCCEEECCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCC
A
C
>Mature Secondary Structure
MDVLDLLVRNTSEVLTVEGSHRERAEDALTPRPGAVVGVREGRIAYVGPEAGLPTGAVGP
CCHHHHHHCCCCCEEEEECCCHHHHHHCCCCCCCCEEEECCCEEEEECCCCCCCCCCCCC
GTEVVDAQGGFVGPGFVDPHTHLVFAGERSAEFDLRNQGATYLEIAKAGGGIASTVQATR
CCCEEECCCCEECCCCCCCCCEEEEECCCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHH
AASEEELVRLALPRTKRLLEQGVTTAEVKSGYGLDLATELKMLRAVRRLGTLTPLELVPT
CCCHHHHHHHHCHHHHHHHHHCCCEEHHCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHH
LLCAHAVPEEYRGKREDYVRLCIEEILPAVAREGLARFCDVFVEDSAFTVDEARRILSAG
HHHHHCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHC
RALGMVPRLHADQLTVCGASELAAELGAATADHLEQVTDAGLKALADANVTAVLVPTSTL
HHHCCCCCCCCCCEEECCHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCEEEEEEECCEE
FLRMRPYAPGRRIRDAGLNVALGTNVNPGSAMSENTALALGLACLENGLTAAEAYWGATR
EEEECCCCCCCCHHHCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHCCCC
GAAMSLGLQQHGRLTVGDAGDLVVFSCASYRHLPYHLGVAHARVVVKAGRIAVRQQMEGC
CHHHCCCHHHCCCEEECCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCC
A
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA