Click here to switch to the map view.

The map label for this gene is yccK [H]

Identifier: 108759206

GI number: 108759206

Start: 2080781

End: 2081836

Strand: Reverse

Name: yccK [H]

Synonym: MXAN_1756

Alternate gene names: 108759206

Gene position: 2081836-2080781 (Counterclockwise)

Preceding gene: 108762587

Following gene: 108762101

Centisome position: 22.78

GC content: 64.2

Gene sequence:

>1056_bases
ATGCGCGCGAGCACGACAAGCGCACCCGCCAGCTCGGCCCAATCCGCCAACCAGGCCTACACCCTGAGGTCCCGCAAGCT
GGGCCACCTGGTGGTGTCGGAGCTTGGCTTCGGATGCATGAGCAACAGCCCTGGCCACTACGGTCCGGGCGTGGACCGTC
CCCAGAGCATCCGTGTGATTCGCGACGCCTATGACCGCGGCATTCGCTTCTTCGATACCGCCGAGGTTTACGGCCCCTAC
GTGAACGAGGAACTCGTCGCCGAAGCACTGGGGCCAGTGCGCAACCACGTGGTCATCGCCACCAAGTTCGGCTTCAAAAT
CGACGGCACGAACGGGTTGGACAGCCGCCCCGAACGCATCCGCCGCGTGGTCGAGGAATCGCTCAAGCGCCTGAAGACGG
ACCGCATCGACCTCTACTACCAGCACCGCGTCGATCTGACCGTCCCCATCGAGGATGTGGCTGGCACCGTCAAGGACCTG
ATCCAGCAGGGCAAGGTGCTGCACTTCGGCCTGTCCGAGCCGAGCGCACGCACCATCCGCCGTGCTCACGCCGTGCAGCC
CTTGGCTGCGATCCAGACCGAGTACTCGCTCATGGAACGCAGCGTGGAGGACAACGGCGTTCTGCAAGCGTGCGAGGAGC
TGGGCATCGGCTTCGTGCCGTGGGGACCGCTCGGTCAAGGCTTCCTTCCCGGCAAGCTGCCCCTGGATGCACAGGCCAGG
TTCGATGCGAAGACGGACCTGCGCAAGACCTTCCCCCGCTTCAGTCGGGAGGTCATGCAGGCCAACCAGTCCATCCTCGA
CTTCCTGAAGGCCTTCGGCGAGAAGAAGGGCGCCACGCGCGCGCAGATTGCCCTGGCCTGGCTGGCAGCACAGAAGCCTT
GGATCGTCCCCATCCCCGGGACAACAAATCTCGATCACTCGCGCGAGAACCTGAGCTCGCTCAACGTCAACCTCACGCCG
GAAGACCTGCGAGAAATCGAAGCGGCCTTCGCCAATATCACCGTGCATGGCGGCCGTATGGACGCGAAGCAGATGGACCA
GATCGGCAAGGACTGA

Upstream 100 bases:

>100_bases
CTCAGATCAACGTGGTGAGTCACATTCACTCGAGAGAAGAAGATTGCTGCTTGGTTTGGCCGCCGCCCCGCTTGCAGCGT
GCGCGTCGGCGCATGGGGGG

Downstream 100 bases:

>100_bases
AATCCATCGGAATCGGATGGGCACAGCCGGGCACAGCTCCACGCCGGGCGGCATGAGGGCCCACCTGAACGACAACGGCA
AGAGGAGCGCAAGTCGCCGG

Product: aldo/keto reductase family oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 351; Mature: 351

Protein sequence:

>351_residues
MRASTTSAPASSAQSANQAYTLRSRKLGHLVVSELGFGCMSNSPGHYGPGVDRPQSIRVIRDAYDRGIRFFDTAEVYGPY
VNEELVAEALGPVRNHVVIATKFGFKIDGTNGLDSRPERIRRVVEESLKRLKTDRIDLYYQHRVDLTVPIEDVAGTVKDL
IQQGKVLHFGLSEPSARTIRRAHAVQPLAAIQTEYSLMERSVEDNGVLQACEELGIGFVPWGPLGQGFLPGKLPLDAQAR
FDAKTDLRKTFPRFSREVMQANQSILDFLKAFGEKKGATRAQIALAWLAAQKPWIVPIPGTTNLDHSRENLSSLNVNLTP
EDLREIEAAFANITVHGGRMDAKQMDQIGKD

Sequences:

>Translated_351_residues
MRASTTSAPASSAQSANQAYTLRSRKLGHLVVSELGFGCMSNSPGHYGPGVDRPQSIRVIRDAYDRGIRFFDTAEVYGPY
VNEELVAEALGPVRNHVVIATKFGFKIDGTNGLDSRPERIRRVVEESLKRLKTDRIDLYYQHRVDLTVPIEDVAGTVKDL
IQQGKVLHFGLSEPSARTIRRAHAVQPLAAIQTEYSLMERSVEDNGVLQACEELGIGFVPWGPLGQGFLPGKLPLDAQAR
FDAKTDLRKTFPRFSREVMQANQSILDFLKAFGEKKGATRAQIALAWLAAQKPWIVPIPGTTNLDHSRENLSSLNVNLTP
EDLREIEAAFANITVHGGRMDAKQMDQIGKD
>Mature_351_residues
MRASTTSAPASSAQSANQAYTLRSRKLGHLVVSELGFGCMSNSPGHYGPGVDRPQSIRVIRDAYDRGIRFFDTAEVYGPY
VNEELVAEALGPVRNHVVIATKFGFKIDGTNGLDSRPERIRRVVEESLKRLKTDRIDLYYQHRVDLTVPIEDVAGTVKDL
IQQGKVLHFGLSEPSARTIRRAHAVQPLAAIQTEYSLMERSVEDNGVLQACEELGIGFVPWGPLGQGFLPGKLPLDAQAR
FDAKTDLRKTFPRFSREVMQANQSILDFLKAFGEKKGATRAQIALAWLAAQKPWIVPIPGTTNLDHSRENLSSLNVNLTP
EDLREIEAAFANITVHGGRMDAKQMDQIGKD

Specific function: Unknown

COG id: COG0667

COG function: function code C; Predicted oxidoreductases (related to aryl-alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI27436969, Length=348, Percent_Identity=27.2988505747126, Blast_Score=111, Evalue=1e-24,
Organism=Homo sapiens, GI4504825, Length=327, Percent_Identity=27.5229357798165, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI27436964, Length=341, Percent_Identity=26.9794721407625, Blast_Score=106, Evalue=3e-23,
Organism=Homo sapiens, GI27436962, Length=341, Percent_Identity=27.5659824046921, Blast_Score=106, Evalue=4e-23,
Organism=Homo sapiens, GI27436966, Length=327, Percent_Identity=27.5229357798165, Blast_Score=105, Evalue=6e-23,
Organism=Homo sapiens, GI27436971, Length=345, Percent_Identity=26.9565217391304, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI223718702, Length=191, Percent_Identity=30.3664921465969, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI41152114, Length=195, Percent_Identity=29.2307692307692, Blast_Score=70, Evalue=2e-12,
Organism=Escherichia coli, GI87081735, Length=313, Percent_Identity=31.629392971246, Blast_Score=133, Evalue=1e-32,
Organism=Escherichia coli, GI1787674, Length=319, Percent_Identity=29.4670846394984, Blast_Score=129, Evalue=3e-31,
Organism=Escherichia coli, GI1789375, Length=291, Percent_Identity=29.2096219931272, Blast_Score=124, Evalue=1e-29,
Organism=Escherichia coli, GI1788070, Length=320, Percent_Identity=29.6875, Blast_Score=112, Evalue=4e-26,
Organism=Escherichia coli, GI1789199, Length=338, Percent_Identity=26.9230769230769, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI48994888, Length=185, Percent_Identity=30.2702702702703, Blast_Score=67, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6319958, Length=296, Percent_Identity=25, Blast_Score=105, Evalue=9e-24,
Organism=Saccharomyces cerevisiae, GI6323998, Length=311, Percent_Identity=24.4372990353698, Blast_Score=105, Evalue=1e-23,
Organism=Saccharomyces cerevisiae, GI6322615, Length=250, Percent_Identity=26, Blast_Score=100, Evalue=4e-22,
Organism=Saccharomyces cerevisiae, GI6325169, Length=335, Percent_Identity=26.2686567164179, Blast_Score=100, Evalue=6e-22,
Organism=Saccharomyces cerevisiae, GI6325384, Length=316, Percent_Identity=25.9493670886076, Blast_Score=95, Evalue=2e-20,
Organism=Saccharomyces cerevisiae, GI6319951, Length=321, Percent_Identity=23.6760124610592, Blast_Score=91, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24646159, Length=224, Percent_Identity=28.125, Blast_Score=72, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24646155, Length=159, Percent_Identity=31.4465408805031, Blast_Score=65, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 38820; Mature: 38820

Theoretical pI: Translated: 8.64; Mature: 8.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRASTTSAPASSAQSANQAYTLRSRKLGHLVVSELGFGCMSNSPGHYGPGVDRPQSIRVI
CCCCCCCCCCHHHHHCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHH
RDAYDRGIRFFDTAEVYGPYVNEELVAEALGPVRNHVVIATKFGFKIDGTNGLDSRPERI
HHHHHCCCEEEECHHHHCCCCCHHHHHHHHHHHHCCEEEEEECCEEECCCCCCCCCHHHH
RRVVEESLKRLKTDRIDLYYQHRVDLTVPIEDVAGTVKDLIQQGKVLHFGLSEPSARTIR
HHHHHHHHHHHHHHHEEEEEEEEEEEEECHHHHHHHHHHHHHCCCEEEECCCCCHHHHHH
RAHAVQPLAAIQTEYSLMERSVEDNGVLQACEELGIGFVPWGPLGQGFLPGKLPLDAQAR
HHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCC
FDAKTDLRKTFPRFSREVMQANQSILDFLKAFGEKKGATRAQIALAWLAAQKPWIVPIPG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCEEEECCC
TTNLDHSRENLSSLNVNLTPEDLREIEAAFANITVHGGRMDAKQMDQIGKD
CCCCCCCHHHHHHCCCCCCHHHHHHHHHHHHHEEEECCCCCHHHHHHCCCC
>Mature Secondary Structure
MRASTTSAPASSAQSANQAYTLRSRKLGHLVVSELGFGCMSNSPGHYGPGVDRPQSIRVI
CCCCCCCCCCHHHHHCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHH
RDAYDRGIRFFDTAEVYGPYVNEELVAEALGPVRNHVVIATKFGFKIDGTNGLDSRPERI
HHHHHCCCEEEECHHHHCCCCCHHHHHHHHHHHHCCEEEEEECCEEECCCCCCCCCHHHH
RRVVEESLKRLKTDRIDLYYQHRVDLTVPIEDVAGTVKDLIQQGKVLHFGLSEPSARTIR
HHHHHHHHHHHHHHHEEEEEEEEEEEEECHHHHHHHHHHHHHCCCEEEECCCCCHHHHHH
RAHAVQPLAAIQTEYSLMERSVEDNGVLQACEELGIGFVPWGPLGQGFLPGKLPLDAQAR
HHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCC
FDAKTDLRKTFPRFSREVMQANQSILDFLKAFGEKKGATRAQIALAWLAAQKPWIVPIPG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCEEEECCC
TTNLDHSRENLSSLNVNLTPEDLREIEAAFANITVHGGRMDAKQMDQIGKD
CCCCCCCHHHHHHCCCCCCHHHHHHHHHHHHHEEEECCCCCHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9274031; 9384377; 9106203 [H]