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The map label for this gene is nhaR [H]

Identifier: 108759049

GI number: 108759049

Start: 893484

End: 894389

Strand: Reverse

Name: nhaR [H]

Synonym: MXAN_0784

Alternate gene names: 108759049

Gene position: 894389-893484 (Counterclockwise)

Preceding gene: 108761990

Following gene: 108763317

Centisome position: 9.79

GC content: 66.11

Gene sequence:

>906_bases
ATGGATATGAGCTGGCTCAACTACCATCACCTCCTGTACTTCTGGACGGTTGCGAGGGCGGGCAGCATCGCCAAGGCAGG
CGAGGAGCTGCACCTGGCGCAGCCCACCATCAGCAGCCAGCTCAAGCTCCTGGAGGAGTCGCTGGGCCACAAGCTGTTCG
AGCGCCAGGGCCGCAAGCTGGTGCTCACCGACGTGGGCCGCACAGTGATGCGCTATGCGGACGAGATCTTCCGCCTGGGG
AACGAGCTGAAGAACGTCGTCTCCGGCTTGCCGCCCGGGCAGCAACTGCGGCTCAACGTCGGTGTGCTCGACGTCATCCC
CAAGCTGGTGGCCGAACAGCTCCTCAAACCCGCGCTCGAAGCAGGCCCGTCGCTGCGCATCATCTGCCGCGAAGGGCCCT
TGCCGCAGCTGCTTGCCTCGCTGGCCCTGCATGAACTGGACGTGGTGCTCGCGGATGCGCCCAGTTCGGAGCCGGTGAGC
GTGCGCTCGTTCAATCACTTGCTCGGCAAGTGCGGCGTGTCCTTCTTCGCGGCGGGGAAGCTGGTCGAACTCAGGGAGAA
CTTCCCTCAGTCGCTGGATGGCGCGCCCGTGCTGCTGCCGTCAGTCGAGTCCTCCGCGCGCCGCTCCATGGACCTGTGGT
TCGAGCGCAAGGGCCTGCGCCCCGTCATCGCGGGTGACTTCGATGACAGCGCGCTGCTCCAGGCCTTTGGCCAGCGCGGG
CACGGGGTCTTCGCCATGCCCAGCGCCATCGAGGCCGAGGTGGAGCGTCAGTTCAACTGCTCCGTCATCGGGCGCACCGA
CGAAATCGAGACCTGCTTCTACGCCATCACTGTCGAGCGGAAGATTCGCCACCCCGCTGTCGTCACCATCGCCGAGGCGG
CGCGCTCGCACATCTTCGGCGAGTGA

Upstream 100 bases:

>100_bases
GGTTGGGCGCGCCCACACGGCGGCGCGACGCAGAGGAAATTAAAGGCCGGGGCTCTATAAGAAAATTAGGTAGTTTAACG
ACAACACTTCGACTATCTCT

Downstream 100 bases:

>100_bases
GCCCAAGGCGCCGCGCTCAGGCCCGAGGTGGCGCGCGGTACACCTCCGTGCCCGCGACCACGGTGGCGAGGACCTGCGCC
TTCACCAACGCCGAGGCGAG

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: Na(+)/H(+) antiporter regulatory protein [H]

Number of amino acids: Translated: 301; Mature: 301

Protein sequence:

>301_residues
MDMSWLNYHHLLYFWTVARAGSIAKAGEELHLAQPTISSQLKLLEESLGHKLFERQGRKLVLTDVGRTVMRYADEIFRLG
NELKNVVSGLPPGQQLRLNVGVLDVIPKLVAEQLLKPALEAGPSLRIICREGPLPQLLASLALHELDVVLADAPSSEPVS
VRSFNHLLGKCGVSFFAAGKLVELRENFPQSLDGAPVLLPSVESSARRSMDLWFERKGLRPVIAGDFDDSALLQAFGQRG
HGVFAMPSAIEAEVERQFNCSVIGRTDEIETCFYAITVERKIRHPAVVTIAEAARSHIFGE

Sequences:

>Translated_301_residues
MDMSWLNYHHLLYFWTVARAGSIAKAGEELHLAQPTISSQLKLLEESLGHKLFERQGRKLVLTDVGRTVMRYADEIFRLG
NELKNVVSGLPPGQQLRLNVGVLDVIPKLVAEQLLKPALEAGPSLRIICREGPLPQLLASLALHELDVVLADAPSSEPVS
VRSFNHLLGKCGVSFFAAGKLVELRENFPQSLDGAPVLLPSVESSARRSMDLWFERKGLRPVIAGDFDDSALLQAFGQRG
HGVFAMPSAIEAEVERQFNCSVIGRTDEIETCFYAITVERKIRHPAVVTIAEAARSHIFGE
>Mature_301_residues
MDMSWLNYHHLLYFWTVARAGSIAKAGEELHLAQPTISSQLKLLEESLGHKLFERQGRKLVLTDVGRTVMRYADEIFRLG
NELKNVVSGLPPGQQLRLNVGVLDVIPKLVAEQLLKPALEAGPSLRIICREGPLPQLLASLALHELDVVLADAPSSEPVS
VRSFNHLLGKCGVSFFAAGKLVELRENFPQSLDGAPVLLPSVESSARRSMDLWFERKGLRPVIAGDFDDSALLQAFGQRG
HGVFAMPSAIEAEVERQFNCSVIGRTDEIETCFYAITVERKIRHPAVVTIAEAARSHIFGE

Specific function: Plays a role in the positive regulation of nhaA (Probable) [H]

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786202, Length=299, Percent_Identity=35.4515050167224, Blast_Score=186, Evalue=2e-48,
Organism=Escherichia coli, GI157672245, Length=245, Percent_Identity=26.9387755102041, Blast_Score=74, Evalue=9e-15,
Organism=Escherichia coli, GI1788297, Length=252, Percent_Identity=28.968253968254, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1789204, Length=149, Percent_Identity=34.2281879194631, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1787806, Length=250, Percent_Identity=22.4, Blast_Score=62, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33197; Mature: 33197

Theoretical pI: Translated: 6.61; Mature: 6.61

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDMSWLNYHHLLYFWTVARAGSIAKAGEELHLAQPTISSQLKLLEESLGHKLFERQGRKL
CCCCHHHHHHHHHHHHHHHCCCHHHCCCHHEECCCCHHHHHHHHHHHHHHHHHHHCCCEE
VLTDVGRTVMRYADEIFRLGNELKNVVSGLPPGQQLRLNVGVLDVIPKLVAEQLLKPALE
EEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHH
AGPSLRIICREGPLPQLLASLALHELDVVLADAPSSEPVSVRSFNHLLGKCGVSFFAAGK
CCCCEEEEECCCCHHHHHHHHHHHHHHEEEECCCCCCCCCHHHHHHHHHHHCHHHHHHCH
LVELRENFPQSLDGAPVLLPSVESSARRSMDLWFERKGLRPVIAGDFDDSALLQAFGQRG
HHHHHHCCCCCCCCCEEEECCCCHHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHCCCC
HGVFAMPSAIEAEVERQFNCSVIGRTDEIETCFYAITVERKIRHPAVVTIAEAARSHIFG
CCEEECCHHHHHHHHHCCCCEEECCCCCHHHEEEEEEEHHHHCCCHHHHHHHHHHHHCCC
E
C
>Mature Secondary Structure
MDMSWLNYHHLLYFWTVARAGSIAKAGEELHLAQPTISSQLKLLEESLGHKLFERQGRKL
CCCCHHHHHHHHHHHHHHHCCCHHHCCCHHEECCCCHHHHHHHHHHHHHHHHHHHCCCEE
VLTDVGRTVMRYADEIFRLGNELKNVVSGLPPGQQLRLNVGVLDVIPKLVAEQLLKPALE
EEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHH
AGPSLRIICREGPLPQLLASLALHELDVVLADAPSSEPVSVRSFNHLLGKCGVSFFAAGK
CCCCEEEEECCCCHHHHHHHHHHHHHHEEEECCCCCCCCCHHHHHHHHHHHCHHHHHHCH
LVELRENFPQSLDGAPVLLPSVESSARRSMDLWFERKGLRPVIAGDFDDSALLQAFGQRG
HHHHHHCCCCCCCCCEEEECCCCHHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHCCCC
HGVFAMPSAIEAEVERQFNCSVIGRTDEIETCFYAITVERKIRHPAVVTIAEAARSHIFG
CCEEECCHHHHHHHHHCCCCEEECCCCCHHHEEEEEEEHHHHCCCHHHHHHHHHHHHCCC
E
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8231807; 9457888; 10952301 [H]