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The map label for this gene is polX [H]

Identifier: 108759043

GI number: 108759043

Start: 3211193

End: 3212635

Strand: Reverse

Name: polX [H]

Synonym: MXAN_2757

Alternate gene names: 108759043

Gene position: 3212635-3211193 (Counterclockwise)

Preceding gene: 108758690

Following gene: 108762955

Centisome position: 35.15

GC content: 70.76

Gene sequence:

>1443_bases
TTGCCCGACGTGGGGCCGAAGAAGGTGGCCACGCTCTGGCGTGAGCTCCAGGTGAGCAGCATCGAGGAGTTGGAGCGGGC
CTGCCGTGAGGGCCGCGTGCGGCAGGTCCGCGGCTTCGGCGCGAAGAGCGAAGCGAAGATGCTGGAAGGCATCGCCCTGT
ACCGCCGCGCGCGCGGCGAGCGCAAGCTGCTGGGCGAGGTACTGCCGGTGGCCACGGCGCTGCTGGAGCGGGTGAAGGCC
GCGCCGGGCGTGGTGCGCGCCAGCCTGGGCGGCAGCGTGCGCCGACAGGCGGAGACCGTGGCGGACGTGGACATCATCGC
CTCCGCGCCGGAGGCGGGACCGGTGCTGGATGCCCTGGCGAACGCACCCGGCGTGGCCGCGGTGCTGGGCAAGGGCGAAA
GCAAATGCTCCGTGCGGTTGGAGGCCGGCGACCTCCAGGTGGACCTGCGCGTGCTGCCCGACGAGGACTTCGCCACCGCC
CTGCACCACTTCACCGGCTCCAAGGCGCACCACATCCGCCTGCGCAACCTGGGGCAGGAACGCGGCCTCAAGATTTCCGA
ATGGGGCGTCCACCGGGACGACGGCACCAAGGTGCCCGTGACGGACGAGTCCGGGCTCTACGCCCTGCTGGACATGCAGT
ACGTGCCCCCCGAGCTGCGGGAGGACAACGGCGAGGTGGAGGCCGCACGCGAGGGACAGCTTCCCCAGGACCTGCTCACG
CTGGAGGACGTCCAGGGTGCGGTCCACGCGCACAGCACCTGGTCCGACGGGCGCAACAGCCTGGAGGAGATGGCGCTCGC
GGCGCGGGCGCTGGGTCTGAAGTACCTGACCGTCACCGAGCACAGCGAGGCAGCCATCTACGCAGGCGGCTTGAAGGTGG
ATGACCTCAAGCGCCAGTGGGAGGAGATCGACCGCATCAACGCGGCGGTCTCCGGCGTGCGGCTGCTCAAGGGCATCGAG
GTCGACATCCTGGAGTCCGGCGCGCTCGACTACGCCGACAGCGTCCTGGAGCAGCTCGAGGTCGTCATCGGCTCCATCCA
CGTCCGGCACGGCATGGACGAGGACCAGATGACGCGCCGGCTGCTGGCCGCGATGGACAACCCCTGCCTCCAGATTCTGG
GGCACCCCACCGGCCGGCTCATCAACAGCCGGGAACCCTACCCCGTCCGCATGGACGAGGTCCTGGAGCGGGCCGCCGAA
CGCGGCGTGGCCGTGGAGGTCAACGGCAAGCCCGCGCGCCTGGACATCAAGGCCGAATATGTCCGGCAGGCTGTGAAGCG
GGGCGTCCGCCTGGTGGTGAGCTGCGACGCGCACCAGAAGGAGGACCTGAGGAACCTGGCCTTCGCGGTGGCTACCGCGC
GCCGGGGCTGGGCCCGAAAGGGGGACGTGCTCAACACGCTCCCGACGGACCGCTTCGTCACCGCGCTGCGCGAGCGCCGG
TGA

Upstream 100 bases:

>100_bases
GCTCGCCGAGAAAATCTCCGAGCTGGTGTCCACCGGCCGGCTCGGCTACCTGGAGGAGCTGCGGGCTTAGTTTCCTCCTG
GGCTGCTGGAGCTGACGCAG

Downstream 100 bases:

>100_bases
TAGGCTGCGGCACCCGCCGATGTCCCGCCTGCCGCCGCTGCTCCTCCTCTGCCTCCTCCCCTTCGCCTCCGCCGCGGCGG
AGGCCGACAAGCCCTCGCGC

Product: DNA polymerase IV

Products: NA

Alternate protein names: DNA polymerase type-X; 3'-5' exodeoxyribonuclease; 3'-5' exonuclease [H]

Number of amino acids: Translated: 480; Mature: 479

Protein sequence:

>480_residues
MPDVGPKKVATLWRELQVSSIEELERACREGRVRQVRGFGAKSEAKMLEGIALYRRARGERKLLGEVLPVATALLERVKA
APGVVRASLGGSVRRQAETVADVDIIASAPEAGPVLDALANAPGVAAVLGKGESKCSVRLEAGDLQVDLRVLPDEDFATA
LHHFTGSKAHHIRLRNLGQERGLKISEWGVHRDDGTKVPVTDESGLYALLDMQYVPPELREDNGEVEAAREGQLPQDLLT
LEDVQGAVHAHSTWSDGRNSLEEMALAARALGLKYLTVTEHSEAAIYAGGLKVDDLKRQWEEIDRINAAVSGVRLLKGIE
VDILESGALDYADSVLEQLEVVIGSIHVRHGMDEDQMTRRLLAAMDNPCLQILGHPTGRLINSREPYPVRMDEVLERAAE
RGVAVEVNGKPARLDIKAEYVRQAVKRGVRLVVSCDAHQKEDLRNLAFAVATARRGWARKGDVLNTLPTDRFVTALRERR

Sequences:

>Translated_480_residues
MPDVGPKKVATLWRELQVSSIEELERACREGRVRQVRGFGAKSEAKMLEGIALYRRARGERKLLGEVLPVATALLERVKA
APGVVRASLGGSVRRQAETVADVDIIASAPEAGPVLDALANAPGVAAVLGKGESKCSVRLEAGDLQVDLRVLPDEDFATA
LHHFTGSKAHHIRLRNLGQERGLKISEWGVHRDDGTKVPVTDESGLYALLDMQYVPPELREDNGEVEAAREGQLPQDLLT
LEDVQGAVHAHSTWSDGRNSLEEMALAARALGLKYLTVTEHSEAAIYAGGLKVDDLKRQWEEIDRINAAVSGVRLLKGIE
VDILESGALDYADSVLEQLEVVIGSIHVRHGMDEDQMTRRLLAAMDNPCLQILGHPTGRLINSREPYPVRMDEVLERAAE
RGVAVEVNGKPARLDIKAEYVRQAVKRGVRLVVSCDAHQKEDLRNLAFAVATARRGWARKGDVLNTLPTDRFVTALRERR
>Mature_479_residues
PDVGPKKVATLWRELQVSSIEELERACREGRVRQVRGFGAKSEAKMLEGIALYRRARGERKLLGEVLPVATALLERVKAA
PGVVRASLGGSVRRQAETVADVDIIASAPEAGPVLDALANAPGVAAVLGKGESKCSVRLEAGDLQVDLRVLPDEDFATAL
HHFTGSKAHHIRLRNLGQERGLKISEWGVHRDDGTKVPVTDESGLYALLDMQYVPPELREDNGEVEAAREGQLPQDLLTL
EDVQGAVHAHSTWSDGRNSLEEMALAARALGLKYLTVTEHSEAAIYAGGLKVDDLKRQWEEIDRINAAVSGVRLLKGIEV
DILESGALDYADSVLEQLEVVIGSIHVRHGMDEDQMTRRLLAAMDNPCLQILGHPTGRLINSREPYPVRMDEVLERAAER
GVAVEVNGKPARLDIKAEYVRQAVKRGVRLVVSCDAHQKEDLRNLAFAVATARRGWARKGDVLNTLPTDRFVTALRERR

Specific function: Strictly DNA-template-directed DNA polymerase, preferentially acting on DNA structures containing gaps from one to a few nucleotides and bearing a phosphate group at the 5' end of the downstream DNA. The fact that PolX is able to conduct filling of a sing

COG id: COG1387

COG function: function code ER; Histidinol phosphatase and related hydrolases of the PHP family

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the PHP family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002054
- InterPro:   IPR010996
- InterPro:   IPR003583
- InterPro:   IPR004013
- InterPro:   IPR003141
- InterPro:   IPR016195
- InterPro:   IPR022311 [H]

Pfam domain/function: PF02811 PHP [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 52650; Mature: 52519

Theoretical pI: Translated: 6.39; Mature: 6.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPDVGPKKVATLWRELQVSSIEELERACREGRVRQVRGFGAKSEAKMLEGIALYRRARGE
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCHHHHHHHHHHHHHHHCCH
RKLLGEVLPVATALLERVKAAPGVVRASLGGSVRRQAETVADVDIIASAPEAGPVLDALA
HHHHHHHHHHHHHHHHHHHCCCCCEEHHCCCHHHHHHHHHHHHHHEECCCCCCHHHHHHH
NAPGVAAVLGKGESKCSVRLEAGDLQVDLRVLPDEDFATALHHFTGSKAHHIRLRNLGQE
CCCCEEEEECCCCCCEEEEEECCCEEEEEEECCCCHHHHHHHHHCCCCEEEEHHHHCCHH
RGLKISEWGVHRDDGTKVPVTDESGLYALLDMQYVPPELREDNGEVEAAREGQLPQDLLT
HCCEEHHCCCCCCCCCCCCCCCCCCCEEEEECCCCCCHHHCCCCCEEECCCCCCCHHHHH
LEDVQGAVHAHSTWSDGRNSLEEMALAARALGLKYLTVTEHSEAAIYAGGLKVDDLKRQW
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCEEEECCCCHHHHHHHH
EEIDRINAAVSGVRLLKGIEVDILESGALDYADSVLEQLEVVIGSIHVRHGMDEDQMTRR
HHHHHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
LLAAMDNPCLQILGHPTGRLINSREPYPVRMDEVLERAAERGVAVEVNGKPARLDIKAEY
HHHHHCCCHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHCCEEEEECCCCEEEEHHHHH
VRQAVKRGVRLVVSCDAHQKEDLRNLAFAVATARRGWARKGDVLNTLPTDRFVTALRERR
HHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHCCCCHHHHHHHHHCC
>Mature Secondary Structure 
PDVGPKKVATLWRELQVSSIEELERACREGRVRQVRGFGAKSEAKMLEGIALYRRARGE
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCHHHHHHHHHHHHHHHCCH
RKLLGEVLPVATALLERVKAAPGVVRASLGGSVRRQAETVADVDIIASAPEAGPVLDALA
HHHHHHHHHHHHHHHHHHHCCCCCEEHHCCCHHHHHHHHHHHHHHEECCCCCCHHHHHHH
NAPGVAAVLGKGESKCSVRLEAGDLQVDLRVLPDEDFATALHHFTGSKAHHIRLRNLGQE
CCCCEEEEECCCCCCEEEEEECCCEEEEEEECCCCHHHHHHHHHCCCCEEEEHHHHCCHH
RGLKISEWGVHRDDGTKVPVTDESGLYALLDMQYVPPELREDNGEVEAAREGQLPQDLLT
HCCEEHHCCCCCCCCCCCCCCCCCCCEEEEECCCCCCHHHCCCCCEEECCCCCCCHHHHH
LEDVQGAVHAHSTWSDGRNSLEEMALAARALGLKYLTVTEHSEAAIYAGGLKVDDLKRQW
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCEEEECCCCHHHHHHHH
EEIDRINAAVSGVRLLKGIEVDILESGALDYADSVLEQLEVVIGSIHVRHGMDEDQMTRR
HHHHHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
LLAAMDNPCLQILGHPTGRLINSREPYPVRMDEVLERAAERGVAVEVNGKPARLDIKAEY
HHHHHCCCHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHCCEEEEECCCCEEEEHHHHH
VRQAVKRGVRLVVSCDAHQKEDLRNLAFAVATARRGWARKGDVLNTLPTDRFVTALRERR
HHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969504; 9384377 [H]