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The map label for this gene is fes [H]

Identifier: 108759022

GI number: 108759022

Start: 1016601

End: 1017686

Strand: Reverse

Name: fes [H]

Synonym: MXAN_0891

Alternate gene names: 108759022

Gene position: 1017686-1016601 (Counterclockwise)

Preceding gene: 108756943

Following gene: 108759606

Centisome position: 11.13

GC content: 70.72

Gene sequence:

>1086_bases
ATGGACGCGAAGACACTGGAGGCGCGGGCCCGCGCCGAGGGAACGCCCGTCATCGAATCGGACACCGCCACCTTCGTGTG
GCGAGGCCGGGGCCCCATCTGCCTCCAAGGTGACTTCCAGGACTGGCGCGGCAAGCCGCTGCCCTTCAAGCGCGTGGCGC
CCGGACTGTGGGCTCGCACGCTGACGCTGCCCGCGGATGCCTACGTCGAATACGCGCTGGAGGACCCGCGCGGCCAGCGC
GTGGAGGACCCGCTCAACCGCCACCCTTCCGACAACGGCTTTGGCGGCATCAACCACTCGTTCCACATGCCCCAGGCCCG
CTCGTCCCTGCCCGCCCGGCACCCGCGCGGCGCGCCTCGGGGCCGCGTCACCCGGCACGTGGTGGACACAGGAGACGTGG
ACCTGCCGGGCCAACGCCGGGTGTACCTGTACGCGCCGCCCACGGACGCGTCGGTGCCCTTGGTGGTGGTGTACGACGGC
GAGGACTATCTGCGCCGCGTCCGCCTGCCGGAGCTGGTGGACACCCTGGTGGCCGAAGGCCGCATGCGCCCGGTGGCCCT
GGCGCTCGTGTGCAACGGCGGTGAGACACGCAGCATGGAGTACGCCTGCAGCGAGTACACGGTGGGGCTGTTGAAGTGGA
AGGTGCTGCCGCTGGCGCGACAGAAACTGTCGCTAGTGGACGAGCGGCGCAGCCCCGGTGCCCACGCGGTGCTGGGGGCC
TCGCTGGGCGGGTTGATGGCGCTCTACACCGGCCTGCGCATGCCGGACGTCTTCGGCCGGGTGCTGTCGCAGTCCGGGGC
CTTCGCGGTGGAGGGCCATGACTTCGTCGTCTTCGACCTGGCGCGGCCCCCACCCCGCCGCCCGCTGGACATCTGGCTGG
ACTGCGGCCGCTTTGAAGGCTTGCTGGAGGGCAACCGCCGCATCGCTCCCGTACTCTCAGAAGCCGGGCATCAGGTGGAA
CTTCGGGAGTACAGCGGTGGGCACAACTACCCTGCGTGGCGTGAGGACCTGGTACACGGCCTGGAGCGCCACTTCCCTCC
CCCGCCCGCCAAGCGCCGGGAGTCATTGCGTTTTTCCGGGCGGTGA

Upstream 100 bases:

>100_bases
CCAGCGCGTGCTGCCCCAGCGCGCCCATGAGGCGGGCTTCGTATTCCGGTACCCGGAGTTGGAGGGCGCGCTGCGCGACC
TGCTGGCCTAGGGTGCGCGG

Downstream 100 bases:

>100_bases
CGCGGGCGCGCCCGCCGTGCGGGGACACTCCGGCGGACGCACGTTAGAGGTGGGACGCAACTGGAGACACACCGCGCCCG
ATAACCTACATGGGAATTCC

Product: putative esterase

Products: Fe [C]

Alternate protein names: Ferric enterobactin esterase [H]

Number of amino acids: Translated: 361; Mature: 361

Protein sequence:

>361_residues
MDAKTLEARARAEGTPVIESDTATFVWRGRGPICLQGDFQDWRGKPLPFKRVAPGLWARTLTLPADAYVEYALEDPRGQR
VEDPLNRHPSDNGFGGINHSFHMPQARSSLPARHPRGAPRGRVTRHVVDTGDVDLPGQRRVYLYAPPTDASVPLVVVYDG
EDYLRRVRLPELVDTLVAEGRMRPVALALVCNGGETRSMEYACSEYTVGLLKWKVLPLARQKLSLVDERRSPGAHAVLGA
SLGGLMALYTGLRMPDVFGRVLSQSGAFAVEGHDFVVFDLARPPPRRPLDIWLDCGRFEGLLEGNRRIAPVLSEAGHQVE
LREYSGGHNYPAWREDLVHGLERHFPPPPAKRRESLRFSGR

Sequences:

>Translated_361_residues
MDAKTLEARARAEGTPVIESDTATFVWRGRGPICLQGDFQDWRGKPLPFKRVAPGLWARTLTLPADAYVEYALEDPRGQR
VEDPLNRHPSDNGFGGINHSFHMPQARSSLPARHPRGAPRGRVTRHVVDTGDVDLPGQRRVYLYAPPTDASVPLVVVYDG
EDYLRRVRLPELVDTLVAEGRMRPVALALVCNGGETRSMEYACSEYTVGLLKWKVLPLARQKLSLVDERRSPGAHAVLGA
SLGGLMALYTGLRMPDVFGRVLSQSGAFAVEGHDFVVFDLARPPPRRPLDIWLDCGRFEGLLEGNRRIAPVLSEAGHQVE
LREYSGGHNYPAWREDLVHGLERHFPPPPAKRRESLRFSGR
>Mature_361_residues
MDAKTLEARARAEGTPVIESDTATFVWRGRGPICLQGDFQDWRGKPLPFKRVAPGLWARTLTLPADAYVEYALEDPRGQR
VEDPLNRHPSDNGFGGINHSFHMPQARSSLPARHPRGAPRGRVTRHVVDTGDVDLPGQRRVYLYAPPTDASVPLVVVYDG
EDYLRRVRLPELVDTLVAEGRMRPVALALVCNGGETRSMEYACSEYTVGLLKWKVLPLARQKLSLVDERRSPGAHAVLGA
SLGGLMALYTGLRMPDVFGRVLSQSGAFAVEGHDFVVFDLARPPPRRPLDIWLDCGRFEGLLEGNRRIAPVLSEAGHQVE
LREYSGGHNYPAWREDLVHGLERHFPPPPAKRRESLRFSGR

Specific function: Upon internalization, ferric enterobactin is processed via an exquisitely specific pathway that is dependent on FES activity, making iron available for metabolic use [H]

COG id: COG2382

COG function: function code P; Enterochelin esterase and related enzymes

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fes family [H]

Homologues:

Organism=Escherichia coli, GI1786799, Length=280, Percent_Identity=26.4285714285714, Blast_Score=69, Evalue=7e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR021764
- InterPro:   IPR000801
- InterPro:   IPR014756 [H]

Pfam domain/function: PF11806 DUF3327; PF00756 Esterase [H]

EC number: NA

Molecular weight: Translated: 40212; Mature: 40212

Theoretical pI: Translated: 9.08; Mature: 9.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDAKTLEARARAEGTPVIESDTATFVWRGRGPICLQGDFQDWRGKPLPFKRVAPGLWART
CCCCHHHHHHHCCCCCEEECCCEEEEECCCCCEEEECCCHHCCCCCCCHHHHCCCHHEEE
LTLPADAYVEYALEDPRGQRVEDPLNRHPSDNGFGGINHSFHMPQARSSLPARHPRGAPR
EECCHHHHHEEEECCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCHHHHCCCCCCCCCCCC
GRVTRHVVDTGDVDLPGQRRVYLYAPPTDASVPLVVVYDGEDYLRRVRLPELVDTLVAEG
CCEEEEEECCCCCCCCCCCEEEEEECCCCCCCCEEEEECCHHHHHHCCCHHHHHHHHHCC
RMRPVALALVCNGGETRSMEYACSEYTVGLLKWKVLPLARQKLSLVDERRSPGAHAVLGA
CCCEEEEEEEECCCCCCCHHHHHHHHEEEHHHEEHHHHHHHHHHHHHHCCCCCCCEEHHH
SLGGLMALYTGLRMPDVFGRVLSQSGAFAVEGHDFVVFDLARPPPRRPLDIWLDCGRFEG
HHHHHHHHHHCCCCHHHHHHHHHCCCCEEECCCCEEEEECCCCCCCCCCEEEEECCCHHH
LLEGNRRIAPVLSEAGHQVELREYSGGHNYPAWREDLVHGLERHFPPPPAKRRESLRFSG
HHCCCCEEHHHHHCCCCEEEEEECCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHCCCCCC
R
C
>Mature Secondary Structure
MDAKTLEARARAEGTPVIESDTATFVWRGRGPICLQGDFQDWRGKPLPFKRVAPGLWART
CCCCHHHHHHHCCCCCEEECCCEEEEECCCCCEEEECCCHHCCCCCCCHHHHCCCHHEEE
LTLPADAYVEYALEDPRGQRVEDPLNRHPSDNGFGGINHSFHMPQARSSLPARHPRGAPR
EECCHHHHHEEEECCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCHHHHCCCCCCCCCCCC
GRVTRHVVDTGDVDLPGQRRVYLYAPPTDASVPLVVVYDGEDYLRRVRLPELVDTLVAEG
CCEEEEEECCCCCCCCCCCEEEEEECCCCCCCCEEEEECCHHHHHHCCCHHHHHHHHHCC
RMRPVALALVCNGGETRSMEYACSEYTVGLLKWKVLPLARQKLSLVDERRSPGAHAVLGA
CCCEEEEEEEECCCCCCCHHHHHHHHEEEHHHEEHHHHHHHHHHHHHHCCCCCCCEEHHH
SLGGLMALYTGLRMPDVFGRVLSQSGAFAVEGHDFVVFDLARPPPRRPLDIWLDCGRFEG
HHHHHHHHHHCCCCHHHHHHHHHCCCCEEECCCCEEEEECCCCCCCCCCEEEEECCCHHH
LLEGNRRIAPVLSEAGHQVELREYSGGHNYPAWREDLVHGLERHFPPPPAKRRESLRFSG
HHCCCCEEHHHHHCCCCEEEEEECCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHCCCCCC
R
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Fe [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ferrienterobactin [C]

Specific reaction: ferrienterobactin = Fe [C]

General reaction: Hydrolase; Acting on ester bonds [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA