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The map label for this gene is yfhA [H]

Identifier: 108758928

GI number: 108758928

Start: 134929

End: 136269

Strand: Reverse

Name: yfhA [H]

Synonym: MXAN_0116

Alternate gene names: 108758928

Gene position: 136269-134929 (Counterclockwise)

Preceding gene: 108761044

Following gene: 108763661

Centisome position: 1.49

GC content: 70.54

Gene sequence:

>1341_bases
GTGGCCCCGTCGAACGAAGAGGATCCCGCGCTGGACCCGACGCTGACGCTGAGCCGCGCGCGGCAAGGCCGGGTCCGGCT
GAAGTTGATGGTGCTGTCCGGCCCCGAGTCCGGCCAGAGCCATGCGCTCACCAGGCCCGAGTACGTGCTTGGCAAGGCCC
CCACGTGCGACATCGTCCTCACCGACAAGACGATTTCCCGCGAGCACCTCAAGCTGACGGTCCACGACGAACACGTGGTG
GCCACGGACATGGGCTCGCGCAACGGCTCCTCGTGTGACGGCCGCCGCTTCACCGAGTTGGAGCTGCACCCAGGCACCGT
CATCACCCTGGGCACCACCGAGCTGAAGCTGGTGCCAGAGGAGTCGGCGAAGCGCACGCTGCTGCTCTCCAACCGCGACC
GCTTCGGCGCGCTGGTGGGCAACAGCCGCCGGATGCGCGAGGTGTTCACCCTGCTGGAGCGCCTGTCCCCGGGCGGCGCG
GACGTGCTCATCCAGGGCGAGACGGGCACCGGCAAGGACCTGTGCGCCGAAGCCATCCACCAGGCCAGCCGCCGCGCCAG
CGGGCCCTTCGTCATCGTGGACCTGGCGGGCGTGGCCCCCTCGCTCATCGAGTCCGAGCTGTTCGGCCACGTGAAGGGCG
CCTTCACCAACGCCCAGAGCGACCGCGCCGGCGCCTTCGAGCGCGCCCACAACGGCACCGTCTTCCTGGATGAAGTCGGT
GAGCTGCCGCTGGAGCTCCAGCCCCGCCTGCTGCGGGTGCTGGAGCGCCGCCAGGTGAAGCGCGTGGGCGCCAACGACTA
CGTCACCGTCAACATGCGCGTGGTGACGGCCACCCACCGGGACCTGGAGGACGCCGTGCGGCAGGGGAAGTTCCGCCGCG
ACCTCTACCACCGGCTCGCCGTGCTCCGCGTGACGATGCCCTCCCTGCGCGAGCGCCCCGAGGACATCCCCCTGCTCATC
GACACCATGCTCGAGCAGACGGGCCGCCCGCCCAGCACCCTGTCGGACCAGACGCGCGCCCTGCTCACCCAGTACCCCTG
GCCCGGCAACGTGCGCGAGCTGCGCAACGTGGTGGAGCAGGTGGTGAACCTGGGCGAGGAGGCCCTCCCGGAGCTGGAGC
CCGCCGACAGCGAGCGGGGCCACAGCGCGGCCGACCTGGACCTGCCCTTCAAGGAGGCCAAGGAGCGGCTCGTGGAAGGC
TTCGAGCGCGACTACCTCCGCAACCTCCTGGAGCGCTGCGAGGGGAACATCTCCCGCGCCTCCCGCGAGGCCGACATCGA
CCGCGTCTACCTCCGCAAGCTCCTGAAAAAGCACGGTATCGAACCGAGCGGCGGCGCTTGA

Upstream 100 bases:

>100_bases
GAGCCTGCCCCCCGGCCCGCGCGACGCAAGCCCCGGCGGTGAAGTCGCCACGGACCCAACGGGTGGCGGGCCGTGTCGGC
CGTGTTAGCGTCCCGCTCCC

Downstream 100 bases:

>100_bases
GCGCTCCGAAAACAACTTTCTCCAGAGATTGGAGATAAGCTCGAATTGGAGCCATGTGGGCTCCGCCCATCCCCCAGGGA
AGACCGCCCATGCGAGTGAA

Product: sigma-54 dependent trancsriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 446; Mature: 445

Protein sequence:

>446_residues
MAPSNEEDPALDPTLTLSRARQGRVRLKLMVLSGPESGQSHALTRPEYVLGKAPTCDIVLTDKTISREHLKLTVHDEHVV
ATDMGSRNGSSCDGRRFTELELHPGTVITLGTTELKLVPEESAKRTLLLSNRDRFGALVGNSRRMREVFTLLERLSPGGA
DVLIQGETGTGKDLCAEAIHQASRRASGPFVIVDLAGVAPSLIESELFGHVKGAFTNAQSDRAGAFERAHNGTVFLDEVG
ELPLELQPRLLRVLERRQVKRVGANDYVTVNMRVVTATHRDLEDAVRQGKFRRDLYHRLAVLRVTMPSLRERPEDIPLLI
DTMLEQTGRPPSTLSDQTRALLTQYPWPGNVRELRNVVEQVVNLGEEALPELEPADSERGHSAADLDLPFKEAKERLVEG
FERDYLRNLLERCEGNISRASREADIDRVYLRKLLKKHGIEPSGGA

Sequences:

>Translated_446_residues
MAPSNEEDPALDPTLTLSRARQGRVRLKLMVLSGPESGQSHALTRPEYVLGKAPTCDIVLTDKTISREHLKLTVHDEHVV
ATDMGSRNGSSCDGRRFTELELHPGTVITLGTTELKLVPEESAKRTLLLSNRDRFGALVGNSRRMREVFTLLERLSPGGA
DVLIQGETGTGKDLCAEAIHQASRRASGPFVIVDLAGVAPSLIESELFGHVKGAFTNAQSDRAGAFERAHNGTVFLDEVG
ELPLELQPRLLRVLERRQVKRVGANDYVTVNMRVVTATHRDLEDAVRQGKFRRDLYHRLAVLRVTMPSLRERPEDIPLLI
DTMLEQTGRPPSTLSDQTRALLTQYPWPGNVRELRNVVEQVVNLGEEALPELEPADSERGHSAADLDLPFKEAKERLVEG
FERDYLRNLLERCEGNISRASREADIDRVYLRKLLKKHGIEPSGGA
>Mature_445_residues
APSNEEDPALDPTLTLSRARQGRVRLKLMVLSGPESGQSHALTRPEYVLGKAPTCDIVLTDKTISREHLKLTVHDEHVVA
TDMGSRNGSSCDGRRFTELELHPGTVITLGTTELKLVPEESAKRTLLLSNRDRFGALVGNSRRMREVFTLLERLSPGGAD
VLIQGETGTGKDLCAEAIHQASRRASGPFVIVDLAGVAPSLIESELFGHVKGAFTNAQSDRAGAFERAHNGTVFLDEVGE
LPLELQPRLLRVLERRQVKRVGANDYVTVNMRVVTATHRDLEDAVRQGKFRRDLYHRLAVLRVTMPSLRERPEDIPLLID
TMLEQTGRPPSTLSDQTRALLTQYPWPGNVRELRNVVEQVVNLGEEALPELEPADSERGHSAADLDLPFKEAKERLVEGF
ERDYLRNLLERCEGNISRASREADIDRVYLRKLLKKHGIEPSGGA

Specific function: Probable member of a two-component regulatory system yfhA/yfhK [H]

COG id: COG2204

COG function: function code T; Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1788905, Length=310, Percent_Identity=42.258064516129, Blast_Score=235, Evalue=4e-63,
Organism=Escherichia coli, GI1788550, Length=325, Percent_Identity=41.5384615384615, Blast_Score=234, Evalue=8e-63,
Organism=Escherichia coli, GI1790299, Length=331, Percent_Identity=40.785498489426, Blast_Score=221, Evalue=5e-59,
Organism=Escherichia coli, GI1790437, Length=311, Percent_Identity=42.1221864951768, Blast_Score=219, Evalue=3e-58,
Organism=Escherichia coli, GI87082152, Length=317, Percent_Identity=41.0094637223975, Blast_Score=215, Evalue=6e-57,
Organism=Escherichia coli, GI87082117, Length=241, Percent_Identity=47.7178423236515, Blast_Score=210, Evalue=1e-55,
Organism=Escherichia coli, GI1789087, Length=263, Percent_Identity=43.3460076045627, Blast_Score=208, Evalue=5e-55,
Organism=Escherichia coli, GI1786524, Length=264, Percent_Identity=45.0757575757576, Blast_Score=208, Evalue=6e-55,
Organism=Escherichia coli, GI1789233, Length=245, Percent_Identity=41.6326530612245, Blast_Score=203, Evalue=2e-53,
Organism=Escherichia coli, GI87081872, Length=323, Percent_Identity=37.7708978328173, Blast_Score=182, Evalue=4e-47,
Organism=Escherichia coli, GI1787583, Length=228, Percent_Identity=40.7894736842105, Blast_Score=175, Evalue=5e-45,
Organism=Escherichia coli, GI1789828, Length=231, Percent_Identity=36.3636363636364, Blast_Score=130, Evalue=2e-31,
Organism=Escherichia coli, GI87081858, Length=292, Percent_Identity=31.1643835616438, Blast_Score=129, Evalue=3e-31,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR011006
- InterPro:   IPR009057
- InterPro:   IPR002078
- InterPro:   IPR001789 [H]

Pfam domain/function: PF00072 Response_reg; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 49565; Mature: 49434

Theoretical pI: Translated: 6.66; Mature: 6.66

Prosite motif: PS50006 FHA_DOMAIN ; PS00676 SIGMA54_INTERACT_2 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAPSNEEDPALDPTLTLSRARQGRVRLKLMVLSGPESGQSHALTRPEYVLGKAPTCDIVL
CCCCCCCCCCCCCHHHHHHCCCCCEEEEEEEEECCCCCCCCCCCCCHHHCCCCCCEEEEE
TDKTISREHLKLTVHDEHVVATDMGSRNGSSCDGRRFTELELHPGTVITLGTTELKLVPE
ECCCCCCCEEEEEEECCEEEEECCCCCCCCCCCCCEEEEEEECCCEEEEECCCEEEECCC
ESAKRTLLLSNRDRFGALVGNSRRMREVFTLLERLSPGGADVLIQGETGTGKDLCAEAIH
CCCCCEEEEECCCHHHHHHCCCHHHHHHHHHHHHCCCCCCEEEEECCCCCCHHHHHHHHH
QASRRASGPFVIVDLAGVAPSLIESELFGHVKGAFTNAQSDRAGAFERAHNGTVFLDEVG
HHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHCCCCCEEEECCC
ELPLELQPRLLRVLERRQVKRVGANDYVTVNMRVVTATHRDLEDAVRQGKFRRDLYHRLA
CCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEEEEEEECHHHHHHHHHCCHHHHHHHHHHH
VLRVTMPSLRERPEDIPLLIDTMLEQTGRPPSTLSDQTRALLTQYPWPGNVRELRNVVEQ
HHHHHCHHHHCCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHH
VVNLGEEALPELEPADSERGHSAADLDLPFKEAKERLVEGFERDYLRNLLERCEGNISRA
HHHCCHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
SREADIDRVYLRKLLKKHGIEPSGGA
HHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
APSNEEDPALDPTLTLSRARQGRVRLKLMVLSGPESGQSHALTRPEYVLGKAPTCDIVL
CCCCCCCCCCCCHHHHHHCCCCCEEEEEEEEECCCCCCCCCCCCCHHHCCCCCCEEEEE
TDKTISREHLKLTVHDEHVVATDMGSRNGSSCDGRRFTELELHPGTVITLGTTELKLVPE
ECCCCCCCEEEEEEECCEEEEECCCCCCCCCCCCCEEEEEEECCCEEEEECCCEEEECCC
ESAKRTLLLSNRDRFGALVGNSRRMREVFTLLERLSPGGADVLIQGETGTGKDLCAEAIH
CCCCCEEEEECCCHHHHHHCCCHHHHHHHHHHHHCCCCCCEEEEECCCCCCHHHHHHHHH
QASRRASGPFVIVDLAGVAPSLIESELFGHVKGAFTNAQSDRAGAFERAHNGTVFLDEVG
HHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHCCCCCEEEECCC
ELPLELQPRLLRVLERRQVKRVGANDYVTVNMRVVTATHRDLEDAVRQGKFRRDLYHRLA
CCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEEEEEEECHHHHHHHHHCCHHHHHHHHHHH
VLRVTMPSLRERPEDIPLLIDTMLEQTGRPPSTLSDQTRALLTQYPWPGNVRELRNVVEQ
HHHHHCHHHHCCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHH
VVNLGEEALPELEPADSERGHSAADLDLPFKEAKERLVEGFERDYLRNLLERCEGNISRA
HHHCCHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
SREADIDRVYLRKLLKKHGIEPSGGA
HHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]