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The map label for this gene is pksE [H]

Identifier: 108758927

GI number: 108758927

Start: 4755331

End: 4756788

Strand: Reverse

Name: pksE [H]

Synonym: MXAN_3934

Alternate gene names: 108758927

Gene position: 4756788-4755331 (Counterclockwise)

Preceding gene: 108756866

Following gene: 108763424

Centisome position: 52.04

GC content: 63.99

Gene sequence:

>1458_bases
GTGTCCGAACGCGCAAGTGATTGCTTGCGCGGATTGACGCTGCATGCACATTTCATGAATACGCCCACGCTCAATGCTGG
TTTGACAATCACCGCGCAATCGCTGGGGAGTTCGACGTTCCGGCGCCGGTTTGGTCTGGCCTATTCCTATGTCTCGGGTG
CCATGTACCGGGGCATCGCGTCCGCTCCGTTGGTGGCGCGGATGGGGAAGGCCGGCTTCATGGGCTTCTTCGGCACGGGC
GGCTGCTCGGTGGAGGAGATCGGCCGGGCGATTGATGAGATTCAATCCCAGCTGACGAAGGGTGAGCCCTTCGGCATGAA
CCTGCTGGCCAGTCATGGCGAATCGTCCCTGGAGCTGGAGACCGTCAAGCTCTACCTGGCCCGAGGTGTCCGCAACGTCG
AGGCCGCCGCGTTCACCCAGGCGACGCCGTCCCTGGTGTTCTACCGCGTCAAGGGACTGCGGCAGGACGCCCAGGGCCGC
GTCGTCTGTGACAACCGCATCATGGCCAAGCTCTCCCGTCCGGAAGTGGCCGAGGTCTTCATGTCTCCGCCGCCTCGGCG
GTTGGTGGAGCAGTTGCTCCGCGACGCGATGATTACGCCGGAGCAGGCCGCGATGGCGGAGCGCGTTCCGCTCAGCCACG
ACATCTGTGTGGAGGCCGACTCCGGTGGCCACACAGACGGCGCGATTCCCACCATCATCCTGCCGACGCTGCTGCGGCTT
CGCGACCGACTGGTGAGCCGGTACGGCTACGAAGAGCCCATCTGCATGGGCCAGGCGGGTGGCATCGGCACGCCGGAGGC
CGCCGCCGCGGCGTTCATCATGGGCGCGGACTTCATCCTCACCGGCTCCATCAATCAGTGCACGGTGGAGTCCGGGATGA
GCTCGGATGCGAAGCTGCTCCTCCAGGAGATGGGTGTGCAGGACACGGACTATGCGCCCGCGGGCGATATGTTCGAGATG
GGCGCCAAGGTGCAGGTGCTCAAGAAAGGCGTCTTCTTCCCGGCGCGCGCGAACAAGCTCTATGCGCTCTACACGCACTA
CGACAGCGTGGATGACATTCCGGAGAAGGTGCGCAAGCAGCTTGAGAGCAGCTTCTTCAAGAAGAGCCTTTCGCAGGTCT
GGGAAGACACCAAGGTGTACCTGCGCCGCAAGGGCCAGCAGGCCACGATTGACAAGGCAGAGGCCCATCCCAAGCAGAAG
CTGGCCCTGATCTTCAGGTGGTACTTCGCTTACTCGACCCGGCTCGCCTTCGCTGGCACCGGCGAGGACCGCGTGAACTA
CCAGGTGCACACCGGGCCCGCGCTCGGGGCCTTCAACCAGTGGGTGAAGGGCACCGAATTGGAGTCCTTCAGCAACCGCC
ACGCGGACGTGATTGCCATGAAGCTGATGACGGAAGCCGCCGAATACCTCAACCGCCAGTACCCCAGGTTGGCCGGCCAG
GAAGGGGGGCAGTCATGA

Upstream 100 bases:

>100_bases
TCCCTCCGTCGCTCAGCAGTTCCTGACGAACAGCCAATCCTGACAACGTTCAAGCTGCCTCGGCTTCGCGGCAAGGCGGC
TTGAATCGGGTCCTCTGGTC

Downstream 100 bases:

>100_bases
CGCGTCTCGAAATCTTGCAGGCGCTCCAGTCGGGACGGATGGCCTTGGCGGACGCCAAGAAGGCGTTGGCCGCCATCGAG
GCGCAGGTGCAGCCGGAGGA

Product: PfaD family protein

Products: NA

Alternate protein names: Malonyl CoA-acyl carrier protein transacylase; MCT [H]

Number of amino acids: Translated: 485; Mature: 484

Protein sequence:

>485_residues
MSERASDCLRGLTLHAHFMNTPTLNAGLTITAQSLGSSTFRRRFGLAYSYVSGAMYRGIASAPLVARMGKAGFMGFFGTG
GCSVEEIGRAIDEIQSQLTKGEPFGMNLLASHGESSLELETVKLYLARGVRNVEAAAFTQATPSLVFYRVKGLRQDAQGR
VVCDNRIMAKLSRPEVAEVFMSPPPRRLVEQLLRDAMITPEQAAMAERVPLSHDICVEADSGGHTDGAIPTIILPTLLRL
RDRLVSRYGYEEPICMGQAGGIGTPEAAAAAFIMGADFILTGSINQCTVESGMSSDAKLLLQEMGVQDTDYAPAGDMFEM
GAKVQVLKKGVFFPARANKLYALYTHYDSVDDIPEKVRKQLESSFFKKSLSQVWEDTKVYLRRKGQQATIDKAEAHPKQK
LALIFRWYFAYSTRLAFAGTGEDRVNYQVHTGPALGAFNQWVKGTELESFSNRHADVIAMKLMTEAAEYLNRQYPRLAGQ
EGGQS

Sequences:

>Translated_485_residues
MSERASDCLRGLTLHAHFMNTPTLNAGLTITAQSLGSSTFRRRFGLAYSYVSGAMYRGIASAPLVARMGKAGFMGFFGTG
GCSVEEIGRAIDEIQSQLTKGEPFGMNLLASHGESSLELETVKLYLARGVRNVEAAAFTQATPSLVFYRVKGLRQDAQGR
VVCDNRIMAKLSRPEVAEVFMSPPPRRLVEQLLRDAMITPEQAAMAERVPLSHDICVEADSGGHTDGAIPTIILPTLLRL
RDRLVSRYGYEEPICMGQAGGIGTPEAAAAAFIMGADFILTGSINQCTVESGMSSDAKLLLQEMGVQDTDYAPAGDMFEM
GAKVQVLKKGVFFPARANKLYALYTHYDSVDDIPEKVRKQLESSFFKKSLSQVWEDTKVYLRRKGQQATIDKAEAHPKQK
LALIFRWYFAYSTRLAFAGTGEDRVNYQVHTGPALGAFNQWVKGTELESFSNRHADVIAMKLMTEAAEYLNRQYPRLAGQ
EGGQS
>Mature_484_residues
SERASDCLRGLTLHAHFMNTPTLNAGLTITAQSLGSSTFRRRFGLAYSYVSGAMYRGIASAPLVARMGKAGFMGFFGTGG
CSVEEIGRAIDEIQSQLTKGEPFGMNLLASHGESSLELETVKLYLARGVRNVEAAAFTQATPSLVFYRVKGLRQDAQGRV
VCDNRIMAKLSRPEVAEVFMSPPPRRLVEQLLRDAMITPEQAAMAERVPLSHDICVEADSGGHTDGAIPTIILPTLLRLR
DRLVSRYGYEEPICMGQAGGIGTPEAAAAAFIMGADFILTGSINQCTVESGMSSDAKLLLQEMGVQDTDYAPAGDMFEMG
AKVQVLKKGVFFPARANKLYALYTHYDSVDDIPEKVRKQLESSFFKKSLSQVWEDTKVYLRRKGQQATIDKAEAHPKQKL
ALIFRWYFAYSTRLAFAGTGEDRVNYQVHTGPALGAFNQWVKGTELESFSNRHADVIAMKLMTEAAEYLNRQYPRLAGQE
GGQS

Specific function: Probably involved in some intermediate steps for the synthesis of the antibiotic polyketide bacillaene which is involved in secondary metabolism. Probably has an acyl transferase activity and could also have a flavin mononucleotide-dependent oxidoreductas

COG id: COG2070

COG function: function code R; Dioxygenases related to 2-nitropropane dioxygenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: In the N-terminal section; belongs to the fabD family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004136
- InterPro:   IPR001227
- InterPro:   IPR014043
- InterPro:   IPR016035
- InterPro:   IPR013785
- InterPro:   IPR004410
- InterPro:   IPR016036
- InterPro:   IPR014179 [H]

Pfam domain/function: PF00698 Acyl_transf_1; PF03060 NPD [H]

EC number: =2.3.1.39 [H]

Molecular weight: Translated: 53252; Mature: 53120

Theoretical pI: Translated: 8.12; Mature: 8.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSERASDCLRGLTLHAHFMNTPTLNAGLTITAQSLGSSTFRRRFGLAYSYVSGAMYRGIA
CCCHHHHHHHHHEEEEEECCCCCCCCCEEEEHHHHCHHHHHHHHHHHHHHHHHHHHHCCC
SAPLVARMGKAGFMGFFGTGGCSVEEIGRAIDEIQSQLTKGEPFGMNLLASHGESSLELE
CCCHHHHHCCCCCCEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCCCHHH
TVKLYLARGVRNVEAAAFTQATPSLVFYRVKGLRQDAQGRVVCDNRIMAKLSRPEVAEVF
HHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHCCCCCEEECCHHHHHCCCCHHHHHH
MSPPPRRLVEQLLRDAMITPEQAAMAERVPLSHDICVEADSGGHTDGAIPTIILPTLLRL
CCCCHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCEEEECCCCCCCCCCCHHHHHHHHHHH
RDRLVSRYGYEEPICMGQAGGIGTPEAAAAAFIMGADFILTGSINQCTVESGMSSDAKLL
HHHHHHHCCCCCCCEECCCCCCCCCHHHHHHHHCCCCEEEECCCCHHHHHCCCCHHHHHH
LQEMGVQDTDYAPAGDMFEMGAKVQVLKKGVFFPARANKLYALYTHYDSVDDIPEKVRKQ
HHHCCCCCCCCCCCCCHHHHCCHHHHHHCCCCCCCCCCCEEEEEEECCCHHHHHHHHHHH
LESSFFKKSLSQVWEDTKVYLRRKGQQATIDKAEAHPKQKLALIFRWYFAYSTRLAFAGT
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCHHHHHHHHHHHHHHHHHEEEEECC
GEDRVNYQVHTGPALGAFNQWVKGTELESFSNRHADVIAMKLMTEAAEYLNRQYPRLAGQ
CCCCEEEEEECCCCHHHHHHHHCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHCCHHCCC
EGGQS
CCCCC
>Mature Secondary Structure 
SERASDCLRGLTLHAHFMNTPTLNAGLTITAQSLGSSTFRRRFGLAYSYVSGAMYRGIA
CCHHHHHHHHHEEEEEECCCCCCCCCEEEEHHHHCHHHHHHHHHHHHHHHHHHHHHCCC
SAPLVARMGKAGFMGFFGTGGCSVEEIGRAIDEIQSQLTKGEPFGMNLLASHGESSLELE
CCCHHHHHCCCCCCEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCCCHHH
TVKLYLARGVRNVEAAAFTQATPSLVFYRVKGLRQDAQGRVVCDNRIMAKLSRPEVAEVF
HHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHCCCCCEEECCHHHHHCCCCHHHHHH
MSPPPRRLVEQLLRDAMITPEQAAMAERVPLSHDICVEADSGGHTDGAIPTIILPTLLRL
CCCCHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCEEEECCCCCCCCCCCHHHHHHHHHHH
RDRLVSRYGYEEPICMGQAGGIGTPEAAAAAFIMGADFILTGSINQCTVESGMSSDAKLL
HHHHHHHCCCCCCCEECCCCCCCCCHHHHHHHHCCCCEEEECCCCHHHHHCCCCHHHHHH
LQEMGVQDTDYAPAGDMFEMGAKVQVLKKGVFFPARANKLYALYTHYDSVDDIPEKVRKQ
HHHCCCCCCCCCCCCCHHHHCCHHHHHHCCCCCCCCCCCEEEEEEECCCHHHHHHHHHHH
LESSFFKKSLSQVWEDTKVYLRRKGQQATIDKAEAHPKQKLALIFRWYFAYSTRLAFAGT
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCHHHHHHHHHHHHHHHHHEEEEECC
GEDRVNYQVHTGPALGAFNQWVKGTELESFSNRHADVIAMKLMTEAAEYLNRQYPRLAGQ
CCCCEEEEEECCCCHHHHHHHHCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHCCHHCCC
EGGQS
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]