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The map label for this gene is moeZ [H]

Identifier: 108758879

GI number: 108758879

Start: 3011902

End: 3013101

Strand: Reverse

Name: moeZ [H]

Synonym: MXAN_2588

Alternate gene names: 108758879

Gene position: 3013101-3011902 (Counterclockwise)

Preceding gene: 108762715

Following gene: 108761883

Centisome position: 32.97

GC content: 69.83

Gene sequence:

>1200_bases
ATGGGCCCAGCCCCTGGGTTATATGCATCCGACATGGCTCGGACCTTCCAAACGCTGCTGGCCGGAGTGAAACAGGAGAT
TCGCGAGGTCTCCGTGGACGACGTGAAGCGGCTGCTGGACGCCCGGGCCTCCGTGCGGCTGCTGGATGTCCGGGAGGCGG
ACGAATACGCCGGGGGCCGGCTGCCAGGGGCCCTCCACATTCCAAGGGGTTACCTGGAGCTGCGCATCGAAAGCCAGGTC
CAGCGTGACGAGGAGCTGGTCGTCTACTGCGCCGGGGGCACCCGCTCCGCCCTGGCCGCCAAGACACTGAAGGAGCTGGG
GTACGAGCGGGTGGCCTCCCTGGCCGGCGGCTACAACCGGTGGAGTGACGCCGCCCTGCCAGTGGAGAAGCCCTTCGTCC
TCACCGCCGAGCAGAAGGAGCGCTACCGCCGCCACCTGAGCCTCCCCGAGGTAGGCGAGGCGGGCCAGGCCAAGCTGCTT
CAAGCCCGCGTCCTGCTGCTGGGGGCCGGCGGGCTGGGCTCGCCGGCGGCGCTGTACCTCGCGGCCGCGGGCGTCGGAAC
GCTAGGCATCGTCGACTCGGACGTGGTCGACCTGAGCAACCTCCAGCGGCAGGTCATCCACACGCGCGAGCGTCAGGGCC
AGCCCAAGGTAGCCAGCGCCCGAGCCGCGATTGAAGCGCTCAATCCGGACGTCAAGGTGGTGGGCTTCGAGGAGCGCCTC
ACCTCGCACAACGTGTTGACGATTCTGGAGGGCTTCGACCTGGTGCTGGACGGAGGGGACAACTTCCCCACGAGGTACCT
GCTCAATGACGCATGCGTCATGCTCGGCAAGCCCAACGTCCACGGCTCCATCTTCCGCTTCGAGGGCCAGGTGACGTCCT
TCGTCCCCGGCCAGGGCCCCTGCTACCGCTGCCTCTACCCCGCCCCGCCCCCGCCCGAGCTGGCGCCCTCGTGTGCGGAG
GCAGGCGTCCTGGGCGTGCTGCCCGGACTCATCGGTCTGCTCCAGGCCACCGAGGCGCTCAAGCTCATCCTCGGCCAGGG
TGCCCCCCTGGTGGGGCGGCTCCTCACCTTCGACGCGCTGGGTACCCGCTTCCAGGAGCTCAAGCTGCGTCGGGACACGC
AGTGCCCCGTGTGCGCGCCGGGCGCGACGGTGGAGCTCATCGACTACGAGCGCTTCTGCGCCGCCCCCACGCCCGCCTGA

Upstream 100 bases:

>100_bases
GGGAAGCCGGCGAAGCGGCGGGGGCGGCGGAAGTCGTGGGGGTGCTGTCCATATCCATGTCTCCTCTAGGGGACTTATAA
CGCCCGGGCCCGGAAAATCC

Downstream 100 bases:

>100_bases
GGACGTCACGCCATGCCCATTCCCGAGATTGCCCCCGCCCGCCTCGCCGAGCTGCTCGCCGGCCCCGCGGAGTCCCGCCC
CGCGCTGCTCGACGTGCGTT

Product: molybdopterin biosynthesis protein MoeB

Products: NA

Alternate protein names: Sulfur carrier protein CysO adenylyltransferase; Sulfur carrier protein CysO sulfurtransferase [H]

Number of amino acids: Translated: 399; Mature: 398

Protein sequence:

>399_residues
MGPAPGLYASDMARTFQTLLAGVKQEIREVSVDDVKRLLDARASVRLLDVREADEYAGGRLPGALHIPRGYLELRIESQV
QRDEELVVYCAGGTRSALAAKTLKELGYERVASLAGGYNRWSDAALPVEKPFVLTAEQKERYRRHLSLPEVGEAGQAKLL
QARVLLLGAGGLGSPAALYLAAAGVGTLGIVDSDVVDLSNLQRQVIHTRERQGQPKVASARAAIEALNPDVKVVGFEERL
TSHNVLTILEGFDLVLDGGDNFPTRYLLNDACVMLGKPNVHGSIFRFEGQVTSFVPGQGPCYRCLYPAPPPPELAPSCAE
AGVLGVLPGLIGLLQATEALKLILGQGAPLVGRLLTFDALGTRFQELKLRRDTQCPVCAPGATVELIDYERFCAAPTPA

Sequences:

>Translated_399_residues
MGPAPGLYASDMARTFQTLLAGVKQEIREVSVDDVKRLLDARASVRLLDVREADEYAGGRLPGALHIPRGYLELRIESQV
QRDEELVVYCAGGTRSALAAKTLKELGYERVASLAGGYNRWSDAALPVEKPFVLTAEQKERYRRHLSLPEVGEAGQAKLL
QARVLLLGAGGLGSPAALYLAAAGVGTLGIVDSDVVDLSNLQRQVIHTRERQGQPKVASARAAIEALNPDVKVVGFEERL
TSHNVLTILEGFDLVLDGGDNFPTRYLLNDACVMLGKPNVHGSIFRFEGQVTSFVPGQGPCYRCLYPAPPPPELAPSCAE
AGVLGVLPGLIGLLQATEALKLILGQGAPLVGRLLTFDALGTRFQELKLRRDTQCPVCAPGATVELIDYERFCAAPTPA
>Mature_398_residues
GPAPGLYASDMARTFQTLLAGVKQEIREVSVDDVKRLLDARASVRLLDVREADEYAGGRLPGALHIPRGYLELRIESQVQ
RDEELVVYCAGGTRSALAAKTLKELGYERVASLAGGYNRWSDAALPVEKPFVLTAEQKERYRRHLSLPEVGEAGQAKLLQ
ARVLLLGAGGLGSPAALYLAAAGVGTLGIVDSDVVDLSNLQRQVIHTRERQGQPKVASARAAIEALNPDVKVVGFEERLT
SHNVLTILEGFDLVLDGGDNFPTRYLLNDACVMLGKPNVHGSIFRFEGQVTSFVPGQGPCYRCLYPAPPPPELAPSCAEA
GVLGVLPGLIGLLQATEALKLILGQGAPLVGRLLTFDALGTRFQELKLRRDTQCPVCAPGATVELIDYERFCAAPTPA

Specific function: Catalyzes the conversion of the sulfur carrier protein CysO to CysO-thiocarboxylate. The reaction is thought to proceed in two steps:first, ATP-dependent activation of CysO as acyl- adenylate (CysO-COOAMP), followed by sulfur transfer to give CysO- thioca

COG id: COG0476

COG function: function code H; Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 rhodanese domain [H]

Homologues:

Organism=Homo sapiens, GI7657339, Length=271, Percent_Identity=47.9704797047971, Blast_Score=217, Evalue=1e-56,
Organism=Homo sapiens, GI4885649, Length=149, Percent_Identity=29.5302013422819, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI38045942, Length=224, Percent_Identity=27.6785714285714, Blast_Score=70, Evalue=4e-12,
Organism=Homo sapiens, GI38045944, Length=216, Percent_Identity=28.2407407407407, Blast_Score=69, Evalue=6e-12,
Organism=Escherichia coli, GI1787048, Length=246, Percent_Identity=43.0894308943089, Blast_Score=189, Evalue=3e-49,
Organism=Escherichia coli, GI87082356, Length=239, Percent_Identity=43.9330543933054, Blast_Score=174, Evalue=6e-45,
Organism=Caenorhabditis elegans, GI17540406, Length=265, Percent_Identity=41.1320754716981, Blast_Score=210, Evalue=1e-54,
Organism=Caenorhabditis elegans, GI193203301, Length=167, Percent_Identity=26.9461077844311, Blast_Score=83, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI71984476, Length=192, Percent_Identity=29.1666666666667, Blast_Score=67, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6321903, Length=281, Percent_Identity=43.4163701067616, Blast_Score=204, Evalue=2e-53,
Organism=Saccharomyces cerevisiae, GI6320598, Length=171, Percent_Identity=30.4093567251462, Blast_Score=88, Evalue=3e-18,
Organism=Saccharomyces cerevisiae, GI6325323, Length=173, Percent_Identity=27.1676300578035, Blast_Score=65, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24582879, Length=262, Percent_Identity=48.8549618320611, Blast_Score=256, Evalue=1e-68,
Organism=Drosophila melanogaster, GI24660640, Length=150, Percent_Identity=33.3333333333333, Blast_Score=92, Evalue=5e-19,
Organism=Drosophila melanogaster, GI20129973, Length=176, Percent_Identity=27.8409090909091, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24641311, Length=229, Percent_Identity=29.2576419213974, Blast_Score=66, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007901
- InterPro:   IPR009036
- InterPro:   IPR016040
- InterPro:   IPR001763
- InterPro:   IPR000594 [H]

Pfam domain/function: PF05237 MoeZ_MoeB; PF00581 Rhodanese; PF00899 ThiF [H]

EC number: NA

Molecular weight: Translated: 42814; Mature: 42683

Theoretical pI: Translated: 6.08; Mature: 6.08

Prosite motif: PS50206 RHODANESE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGPAPGLYASDMARTFQTLLAGVKQEIREVSVDDVKRLLDARASVRLLDVREADEYAGGR
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCEEEEEECCHHHHCCCC
LPGALHIPRGYLELRIESQVQRDEELVVYCAGGTRSALAAKTLKELGYERVASLAGGYNR
CCCEEECCCCEEEEEEHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCC
WSDAALPVEKPFVLTAEQKERYRRHLSLPEVGEAGQAKLLQARVLLLGAGGLGSPAALYL
CCCCCCCCCCCEEEECHHHHHHHHHCCCCCCCCCCHHHHHHEEEEEEECCCCCCHHHHHH
AAAGVGTLGIVDSDVVDLSNLQRQVIHTRERQGQPKVASARAAIEALNPDVKVVGFEERL
HHCCCCEEECCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCEEEEEHHHHH
TSHNVLTILEGFDLVLDGGDNFPTRYLLNDACVMLGKPNVHGSIFRFEGQVTSFVPGQGP
CCCCEEEEECCCEEEEECCCCCCHHHHHCCCEEEECCCCCCCEEEEECCCEEEECCCCCC
CYRCLYPAPPPPELAPSCAEAGVLGVLPGLIGLLQATEALKLILGQGAPLVGRLLTFDAL
EEEEECCCCCCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
GTRFQELKLRRDTQCPVCAPGATVELIDYERFCAAPTPA
HHHHHHHHHCCCCCCCEECCCCEEEEEEHHHHCCCCCCC
>Mature Secondary Structure 
GPAPGLYASDMARTFQTLLAGVKQEIREVSVDDVKRLLDARASVRLLDVREADEYAGGR
CCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCEEEEEECCHHHHCCCC
LPGALHIPRGYLELRIESQVQRDEELVVYCAGGTRSALAAKTLKELGYERVASLAGGYNR
CCCEEECCCCEEEEEEHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCC
WSDAALPVEKPFVLTAEQKERYRRHLSLPEVGEAGQAKLLQARVLLLGAGGLGSPAALYL
CCCCCCCCCCCEEEECHHHHHHHHHCCCCCCCCCCHHHHHHEEEEEEECCCCCCHHHHHH
AAAGVGTLGIVDSDVVDLSNLQRQVIHTRERQGQPKVASARAAIEALNPDVKVVGFEERL
HHCCCCEEECCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCEEEEEHHHHH
TSHNVLTILEGFDLVLDGGDNFPTRYLLNDACVMLGKPNVHGSIFRFEGQVTSFVPGQGP
CCCCEEEEECCCEEEEECCCCCCHHHHHCCCEEEECCCCCCCEEEEECCCEEEECCCCCC
CYRCLYPAPPPPELAPSCAEAGVLGVLPGLIGLLQATEALKLILGQGAPLVGRLLTFDAL
EEEEECCCCCCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
GTRFQELKLRRDTQCPVCAPGATVELIDYERFCAAPTPA
HHHHHHHHHCCCCCCCEECCCCEEEEEEHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]