Definition Myxococcus xanthus DK 1622 chromosome, complete genome.
Accession NC_008095
Length 9,139,763

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The map label for this gene is hflB [C]

Identifier: 108758871

GI number: 108758871

Start: 3224588

End: 3226723

Strand: Reverse

Name: hflB [C]

Synonym: MXAN_2773

Alternate gene names: 108758871

Gene position: 3226723-3224588 (Counterclockwise)

Preceding gene: 108763051

Following gene: 108757698

Centisome position: 35.3

GC content: 69.43

Gene sequence:

>2136_bases
GTGACCGTCGCGACACGGGAACATACGCGGACGCTGCGCGCCGCCGAGTCCCTCGGCAAAGACCTGGGCCGTGGCCTCGC
CCGCATGGACCCCGCCGACATGAAGCGGCTGGGGGCGCATGTCGGCGACATCGTCACGCTGTCCGGCAAGCGCCGCAGCG
CGGCCAAGGTGATGCCCTCCTACCCGGACGCCCGGGGGCGCGGAATCCTCCAGATTGACGGTGTGACCCGGGCCAACACC
GGGGTGCAGTTGGACGAACCGGTGAAGCTGACCCTGGCCCCCGCCCGACACGCCGAGAAGGTCGTGCTGGCGCCCCTGGA
GTTCACCCCCGCGCAGCGTGACCTGGCCTACATCGGCACGCTGCTGGACGGACTGCCGGTGGTGAAGGGAGACCGGGTCC
GCGCGCTGCTGTTCGGCAGCCGCACGGCCGACTTCCGCGTCGTCGAGACCACTCCTGTGGGGGCGGTGGTGATTCACCCC
AACACCCTGCTGGAGGTCGCCAAGGCGCCGGAGAAGGAGAAGGTGACGCACGAGCGGGCGCGCGCCGTCAGCTACGAGGA
CGTGGGTGGGCTGAAGCGGGAGCTGGGCCGCATCCGCGAGATCGTGGAGCTGCCGCTGCGGTATCCGGAGGTGTTCGAGC
GGCTCGGGATCGACGCCCCCAAGGGGGTGCTGCTGTATGGCCCGCCGGGCTGCGGCAAGACGCTGATCGCCCGGGCGGTG
GCCCACGAGACGGCGGCGGCGTTCTTCACCATCACCGGCCCGGAGATCATGCACAAGTTCTACGGAGAGAGTGAGGCCCA
CCTCCGGCAGATCTTCGACGAGGCCCAGCGCAGGGCCCCGGCCATCATCTTCGTGGACGAGATAGACGCCATCGCTCCCC
GGCGCGAGAACGTGCAGGGCGAGGTGGAGAAGCGGGTGGTGGCGCAGTTGCTGTCGCTGATGGACGGCCTGGCCCAACGC
CGGCACGTCATCGTGCTGGCTGCCACCAACATCCCCAACGTGCTGGACCCGGCGCTGCGTCGCCCGGGGCGGTTCGACCG
CGAGATCGCCATCTCCATCCCCGACCGCACGGCGCGCAAGGAGATCCTCGCCATCCACAGCCGGGGCATGCCGCTGGCAG
AGGACGTGGACCTGGACCATCTGGCGGCCGTGACGCATGGCTTCGTAGGCGCAGACCTCCAGGCCCTGTGCCGCGAGGCG
GCGATGCTCTGCCTGCGCCGGCTGATTCCCCACATCGACTTCGCCTCGGCCGAGATTCCCTACGACGAGCTGATACAGGT
CCAGGTGACGATGGCCGACTTCCAGGCGGCGCTGCACGAGGTGGGGCCATCGGCGATCCGCGAGGTGTTCGTGGAGACCC
CGGACGTGGGCTGGAAGGACGTGGGCGGACTGGGGCAGCTCAAGCAGCGGCTCATCGAGGCGGTGGAGTGGCCACTCCGG
TACCCCGAGGAGTTCGCGCGGGCCAAGGTCCGCCCCCCCAAGGGCGTGCTGCTGAGCGGCCCTCCTGGCTGCGGCAAGAC
GCTGATGGCCAAGGCCGCCGCCCACGAGAGCCAGGTCAACTTCATCTCGGTCAAGGGCCCGGCGCTGCTCAGCAAGTTCG
TGGGGGAGTCCGAGAGGGGGGTGCGCGAGACCTTTCAGAAGGCCCGTCAAGCGGCCCCCTGCATCATCTTCTTCGATGAG
ATCGACTCGCTCGTGCCGACGCGCTCCGCCGGGGGAATGGACGAGCGCGTCACAGAGAGGGTCGTCAGCCAGTTCCTGGC
CGAGATGGATGGCATCGAGGAGCTGACCGGCGTGCTGGTGCTCGCGGCCACCAACCGCGCGGACCTGCTCGACCCTGCGC
TGCTGCGCCCGGGACGCTTCGACCTGCTCGTCGATGTGCCGCTGCCGGACCGCGAAGCGCGGCGCGACATCTTCCAGGTC
CACCTGCGCGACAAGCCGGTGGAGAAGGACCTCGACCTGGGCGGACTCGCTGCACGCAGCGAGTCCTTCTCCGGCGCCGA
CATCCAGGCCGTGTGCAATCAGGCCGCCTGGGAAGCCGTGCGTCACGTCATCAGCGGCAAGGGAAAGCGGCTCGTCATCA
CATCCGAGAGCCTGCTCAAGGCGATCCGAGGGCACAAGGAGGCACGCCGGCCATGA

Upstream 100 bases:

>100_bases
AGGTCCTGCTCCCCAGGCGCTTCACCCGCCGGCAGATGCACACCAACTGCCGCAACGGCGTCCTCGAGATCCGCCTCACC
GCCCAGGAGGAGCGCCGCTC

Downstream 100 bases:

>100_bases
GAGCCCACAGCAATCCCGGTGTGCAGGGGCGACGCAAGGGCCAGCAGGCCCTGTACGTCTATGGCTTCACGCGGGCAGGG
GCGGTGGAGCACTTCTCCGT

Product: AAA family ATPase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 711; Mature: 710

Protein sequence:

>711_residues
MTVATREHTRTLRAAESLGKDLGRGLARMDPADMKRLGAHVGDIVTLSGKRRSAAKVMPSYPDARGRGILQIDGVTRANT
GVQLDEPVKLTLAPARHAEKVVLAPLEFTPAQRDLAYIGTLLDGLPVVKGDRVRALLFGSRTADFRVVETTPVGAVVIHP
NTLLEVAKAPEKEKVTHERARAVSYEDVGGLKRELGRIREIVELPLRYPEVFERLGIDAPKGVLLYGPPGCGKTLIARAV
AHETAAAFFTITGPEIMHKFYGESEAHLRQIFDEAQRRAPAIIFVDEIDAIAPRRENVQGEVEKRVVAQLLSLMDGLAQR
RHVIVLAATNIPNVLDPALRRPGRFDREIAISIPDRTARKEILAIHSRGMPLAEDVDLDHLAAVTHGFVGADLQALCREA
AMLCLRRLIPHIDFASAEIPYDELIQVQVTMADFQAALHEVGPSAIREVFVETPDVGWKDVGGLGQLKQRLIEAVEWPLR
YPEEFARAKVRPPKGVLLSGPPGCGKTLMAKAAAHESQVNFISVKGPALLSKFVGESERGVRETFQKARQAAPCIIFFDE
IDSLVPTRSAGGMDERVTERVVSQFLAEMDGIEELTGVLVLAATNRADLLDPALLRPGRFDLLVDVPLPDREARRDIFQV
HLRDKPVEKDLDLGGLAARSESFSGADIQAVCNQAAWEAVRHVISGKGKRLVITSESLLKAIRGHKEARRP

Sequences:

>Translated_711_residues
MTVATREHTRTLRAAESLGKDLGRGLARMDPADMKRLGAHVGDIVTLSGKRRSAAKVMPSYPDARGRGILQIDGVTRANT
GVQLDEPVKLTLAPARHAEKVVLAPLEFTPAQRDLAYIGTLLDGLPVVKGDRVRALLFGSRTADFRVVETTPVGAVVIHP
NTLLEVAKAPEKEKVTHERARAVSYEDVGGLKRELGRIREIVELPLRYPEVFERLGIDAPKGVLLYGPPGCGKTLIARAV
AHETAAAFFTITGPEIMHKFYGESEAHLRQIFDEAQRRAPAIIFVDEIDAIAPRRENVQGEVEKRVVAQLLSLMDGLAQR
RHVIVLAATNIPNVLDPALRRPGRFDREIAISIPDRTARKEILAIHSRGMPLAEDVDLDHLAAVTHGFVGADLQALCREA
AMLCLRRLIPHIDFASAEIPYDELIQVQVTMADFQAALHEVGPSAIREVFVETPDVGWKDVGGLGQLKQRLIEAVEWPLR
YPEEFARAKVRPPKGVLLSGPPGCGKTLMAKAAAHESQVNFISVKGPALLSKFVGESERGVRETFQKARQAAPCIIFFDE
IDSLVPTRSAGGMDERVTERVVSQFLAEMDGIEELTGVLVLAATNRADLLDPALLRPGRFDLLVDVPLPDREARRDIFQV
HLRDKPVEKDLDLGGLAARSESFSGADIQAVCNQAAWEAVRHVISGKGKRLVITSESLLKAIRGHKEARRP
>Mature_710_residues
TVATREHTRTLRAAESLGKDLGRGLARMDPADMKRLGAHVGDIVTLSGKRRSAAKVMPSYPDARGRGILQIDGVTRANTG
VQLDEPVKLTLAPARHAEKVVLAPLEFTPAQRDLAYIGTLLDGLPVVKGDRVRALLFGSRTADFRVVETTPVGAVVIHPN
TLLEVAKAPEKEKVTHERARAVSYEDVGGLKRELGRIREIVELPLRYPEVFERLGIDAPKGVLLYGPPGCGKTLIARAVA
HETAAAFFTITGPEIMHKFYGESEAHLRQIFDEAQRRAPAIIFVDEIDAIAPRRENVQGEVEKRVVAQLLSLMDGLAQRR
HVIVLAATNIPNVLDPALRRPGRFDREIAISIPDRTARKEILAIHSRGMPLAEDVDLDHLAAVTHGFVGADLQALCREAA
MLCLRRLIPHIDFASAEIPYDELIQVQVTMADFQAALHEVGPSAIREVFVETPDVGWKDVGGLGQLKQRLIEAVEWPLRY
PEEFARAKVRPPKGVLLSGPPGCGKTLMAKAAAHESQVNFISVKGPALLSKFVGESERGVRETFQKARQAAPCIIFFDEI
DSLVPTRSAGGMDERVTERVVSQFLAEMDGIEELTGVLVLAATNRADLLDPALLRPGRFDLLVDVPLPDREARRDIFQVH
LRDKPVEKDLDLGGLAARSESFSGADIQAVCNQAAWEAVRHVISGKGKRLVITSESLLKAIRGHKEARRP

Specific function: Seems To Act As An ATP-Dependent Zinc Metallopeptidase. Involved In The Degradation Of Sigma-32. Degrades Carboxy- Terminal-Tagged Cytoplasmic Proteins. These Proteins Are Tagged With An 11-Amino-Acid Nonpolar Destabilizing Tail VIa A Mechanism Involving

COG id: COG0464

COG function: function code O; ATPases of the AAA+ class

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AAA ATPase family. CDC48 subfamily [H]

Homologues:

Organism=Homo sapiens, GI6005942, Length=655, Percent_Identity=47.7862595419847, Blast_Score=610, Evalue=1e-174,
Organism=Homo sapiens, GI157671927, Length=525, Percent_Identity=51.4285714285714, Blast_Score=536, Evalue=1e-152,
Organism=Homo sapiens, GI45643123, Length=570, Percent_Identity=44.0350877192982, Blast_Score=439, Evalue=1e-123,
Organism=Homo sapiens, GI45643125, Length=570, Percent_Identity=44.0350877192982, Blast_Score=439, Evalue=1e-123,
Organism=Homo sapiens, GI229577436, Length=499, Percent_Identity=42.4849699398798, Blast_Score=385, Evalue=1e-106,
Organism=Homo sapiens, GI4505725, Length=487, Percent_Identity=36.5503080082135, Blast_Score=269, Evalue=6e-72,
Organism=Homo sapiens, GI194018488, Length=496, Percent_Identity=36.2903225806452, Blast_Score=246, Evalue=6e-65,
Organism=Homo sapiens, GI24497618, Length=274, Percent_Identity=45.2554744525547, Blast_Score=245, Evalue=8e-65,
Organism=Homo sapiens, GI153792536, Length=276, Percent_Identity=43.8405797101449, Blast_Score=239, Evalue=8e-63,
Organism=Homo sapiens, GI5729991, Length=323, Percent_Identity=39.3188854489164, Blast_Score=218, Evalue=1e-56,
Organism=Homo sapiens, GI89064750, Length=323, Percent_Identity=39.3188854489164, Blast_Score=218, Evalue=1e-56,
Organism=Homo sapiens, GI24430151, Length=248, Percent_Identity=44.758064516129, Blast_Score=218, Evalue=1e-56,
Organism=Homo sapiens, GI24430155, Length=255, Percent_Identity=43.5294117647059, Blast_Score=217, Evalue=3e-56,
Organism=Homo sapiens, GI24497435, Length=246, Percent_Identity=43.4959349593496, Blast_Score=209, Evalue=1e-53,
Organism=Homo sapiens, GI195539395, Length=236, Percent_Identity=44.4915254237288, Blast_Score=207, Evalue=4e-53,
Organism=Homo sapiens, GI21361144, Length=227, Percent_Identity=44.9339207048458, Blast_Score=204, Evalue=3e-52,
Organism=Homo sapiens, GI4506209, Length=248, Percent_Identity=42.3387096774194, Blast_Score=203, Evalue=5e-52,
Organism=Homo sapiens, GI156564401, Length=403, Percent_Identity=35.4838709677419, Blast_Score=197, Evalue=3e-50,
Organism=Homo sapiens, GI300192933, Length=255, Percent_Identity=44.7058823529412, Blast_Score=194, Evalue=2e-49,
Organism=Homo sapiens, GI4507173, Length=238, Percent_Identity=41.5966386554622, Blast_Score=182, Evalue=1e-45,
Organism=Homo sapiens, GI5901990, Length=271, Percent_Identity=39.8523985239852, Blast_Score=181, Evalue=2e-45,
Organism=Homo sapiens, GI14149767, Length=275, Percent_Identity=37.4545454545455, Blast_Score=174, Evalue=2e-43,
Organism=Homo sapiens, GI62177112, Length=275, Percent_Identity=37.4545454545455, Blast_Score=174, Evalue=2e-43,
Organism=Homo sapiens, GI310125280, Length=268, Percent_Identity=40.6716417910448, Blast_Score=172, Evalue=1e-42,
Organism=Homo sapiens, GI310125282, Length=270, Percent_Identity=40.3703703703704, Blast_Score=172, Evalue=1e-42,
Organism=Homo sapiens, GI21327685, Length=225, Percent_Identity=39.5555555555556, Blast_Score=166, Evalue=5e-41,
Organism=Homo sapiens, GI7657689, Length=225, Percent_Identity=39.5555555555556, Blast_Score=166, Evalue=6e-41,
Organism=Homo sapiens, GI226371754, Length=306, Percent_Identity=35.2941176470588, Blast_Score=166, Evalue=8e-41,
Organism=Homo sapiens, GI7019569, Length=241, Percent_Identity=40.2489626556017, Blast_Score=164, Evalue=2e-40,
Organism=Homo sapiens, GI31377644, Length=247, Percent_Identity=38.8663967611336, Blast_Score=159, Evalue=7e-39,
Organism=Homo sapiens, GI17865802, Length=240, Percent_Identity=40, Blast_Score=158, Evalue=1e-38,
Organism=Homo sapiens, GI31742536, Length=266, Percent_Identity=33.8345864661654, Blast_Score=154, Evalue=2e-37,
Organism=Homo sapiens, GI112789543, Length=266, Percent_Identity=33.8345864661654, Blast_Score=154, Evalue=2e-37,
Organism=Homo sapiens, GI11875211, Length=267, Percent_Identity=34.4569288389513, Blast_Score=142, Evalue=8e-34,
Organism=Homo sapiens, GI40806170, Length=267, Percent_Identity=34.4569288389513, Blast_Score=142, Evalue=8e-34,
Organism=Homo sapiens, GI64084766, Length=292, Percent_Identity=31.5068493150685, Blast_Score=120, Evalue=7e-27,
Organism=Homo sapiens, GI40806173, Length=146, Percent_Identity=41.7808219178082, Blast_Score=115, Evalue=2e-25,
Organism=Homo sapiens, GI116292174, Length=224, Percent_Identity=32.5892857142857, Blast_Score=98, Evalue=2e-20,
Organism=Escherichia coli, GI1789568, Length=243, Percent_Identity=46.0905349794239, Blast_Score=197, Evalue=2e-51,
Organism=Caenorhabditis elegans, GI17532375, Length=676, Percent_Identity=46.301775147929, Blast_Score=603, Evalue=1e-173,
Organism=Caenorhabditis elegans, GI17531535, Length=688, Percent_Identity=45.0581395348837, Blast_Score=594, Evalue=1e-170,
Organism=Caenorhabditis elegans, GI17537217, Length=566, Percent_Identity=39.3992932862191, Blast_Score=384, Evalue=1e-106,
Organism=Caenorhabditis elegans, GI17508053, Length=468, Percent_Identity=34.1880341880342, Blast_Score=251, Evalue=1e-66,
Organism=Caenorhabditis elegans, GI133931034, Length=279, Percent_Identity=44.0860215053763, Blast_Score=236, Evalue=3e-62,
Organism=Caenorhabditis elegans, GI193206114, Length=279, Percent_Identity=44.0860215053763, Blast_Score=236, Evalue=3e-62,
Organism=Caenorhabditis elegans, GI193206116, Length=279, Percent_Identity=44.0860215053763, Blast_Score=236, Evalue=4e-62,
Organism=Caenorhabditis elegans, GI17562804, Length=473, Percent_Identity=33.4038054968288, Blast_Score=223, Evalue=3e-58,
Organism=Caenorhabditis elegans, GI25153574, Length=486, Percent_Identity=31.0699588477366, Blast_Score=214, Evalue=9e-56,
Organism=Caenorhabditis elegans, GI17554786, Length=247, Percent_Identity=44.1295546558704, Blast_Score=213, Evalue=3e-55,
Organism=Caenorhabditis elegans, GI25144278, Length=247, Percent_Identity=44.5344129554656, Blast_Score=211, Evalue=8e-55,
Organism=Caenorhabditis elegans, GI71987364, Length=272, Percent_Identity=42.2794117647059, Blast_Score=211, Evalue=1e-54,
Organism=Caenorhabditis elegans, GI25144281, Length=247, Percent_Identity=44.5344129554656, Blast_Score=211, Evalue=1e-54,
Organism=Caenorhabditis elegans, GI17563250, Length=267, Percent_Identity=41.9475655430712, Blast_Score=211, Evalue=1e-54,
Organism=Caenorhabditis elegans, GI71987372, Length=272, Percent_Identity=42.2794117647059, Blast_Score=211, Evalue=1e-54,
Organism=Caenorhabditis elegans, GI17505546, Length=304, Percent_Identity=38.4868421052632, Blast_Score=203, Evalue=2e-52,
Organism=Caenorhabditis elegans, GI17554784, Length=255, Percent_Identity=42.3529411764706, Blast_Score=202, Evalue=7e-52,
Organism=Caenorhabditis elegans, GI17563248, Length=259, Percent_Identity=41.3127413127413, Blast_Score=201, Evalue=1e-51,
Organism=Caenorhabditis elegans, GI193209502, Length=226, Percent_Identity=46.4601769911504, Blast_Score=199, Evalue=4e-51,
Organism=Caenorhabditis elegans, GI17508701, Length=240, Percent_Identity=43.75, Blast_Score=197, Evalue=1e-50,
Organism=Caenorhabditis elegans, GI71994521, Length=254, Percent_Identity=44.0944881889764, Blast_Score=179, Evalue=5e-45,
Organism=Caenorhabditis elegans, GI17554264, Length=207, Percent_Identity=47.3429951690821, Blast_Score=176, Evalue=4e-44,
Organism=Caenorhabditis elegans, GI32563584, Length=293, Percent_Identity=39.5904436860068, Blast_Score=172, Evalue=6e-43,
Organism=Caenorhabditis elegans, GI17508421, Length=287, Percent_Identity=40.418118466899, Blast_Score=171, Evalue=1e-42,
Organism=Caenorhabditis elegans, GI115534323, Length=247, Percent_Identity=41.2955465587045, Blast_Score=167, Evalue=2e-41,
Organism=Caenorhabditis elegans, GI133901662, Length=415, Percent_Identity=31.566265060241, Blast_Score=164, Evalue=2e-40,
Organism=Caenorhabditis elegans, GI133901658, Length=415, Percent_Identity=31.3253012048193, Blast_Score=163, Evalue=3e-40,
Organism=Caenorhabditis elegans, GI25146157, Length=325, Percent_Identity=33.2307692307692, Blast_Score=160, Evalue=2e-39,
Organism=Caenorhabditis elegans, GI86561515, Length=240, Percent_Identity=39.1666666666667, Blast_Score=160, Evalue=3e-39,
Organism=Caenorhabditis elegans, GI17541226, Length=294, Percent_Identity=32.312925170068, Blast_Score=147, Evalue=2e-35,
Organism=Caenorhabditis elegans, GI17541224, Length=243, Percent_Identity=35.3909465020576, Blast_Score=146, Evalue=4e-35,
Organism=Caenorhabditis elegans, GI17560432, Length=271, Percent_Identity=37.2693726937269, Blast_Score=144, Evalue=2e-34,
Organism=Caenorhabditis elegans, GI17570397, Length=117, Percent_Identity=42.7350427350427, Blast_Score=81, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI32566590, Length=117, Percent_Identity=42.7350427350427, Blast_Score=81, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6320077, Length=667, Percent_Identity=46.1769115442279, Blast_Score=582, Evalue=1e-167,
Organism=Saccharomyces cerevisiae, GI6323429, Length=504, Percent_Identity=48.015873015873, Blast_Score=469, Evalue=1e-132,
Organism=Saccharomyces cerevisiae, GI6322994, Length=572, Percent_Identity=38.2867132867133, Blast_Score=405, Evalue=1e-114,
Organism=Saccharomyces cerevisiae, GI6322651, Length=660, Percent_Identity=28.1818181818182, Blast_Score=244, Evalue=4e-65,
Organism=Saccharomyces cerevisiae, GI6321709, Length=272, Percent_Identity=44.1176470588235, Blast_Score=238, Evalue=3e-63,
Organism=Saccharomyces cerevisiae, GI6320197, Length=305, Percent_Identity=40.9836065573771, Blast_Score=224, Evalue=3e-59,
Organism=Saccharomyces cerevisiae, GI6324000, Length=431, Percent_Identity=34.1067285382831, Blast_Score=218, Evalue=3e-57,
Organism=Saccharomyces cerevisiae, GI6321390, Length=241, Percent_Identity=45.2282157676349, Blast_Score=212, Evalue=2e-55,
Organism=Saccharomyces cerevisiae, GI6322704, Length=240, Percent_Identity=43.3333333333333, Blast_Score=204, Evalue=6e-53,
Organism=Saccharomyces cerevisiae, GI6324691, Length=237, Percent_Identity=43.0379746835443, Blast_Score=195, Evalue=2e-50,
Organism=Saccharomyces cerevisiae, GI6324833, Length=272, Percent_Identity=38.6029411764706, Blast_Score=195, Evalue=2e-50,
Organism=Saccharomyces cerevisiae, GI6320602, Length=229, Percent_Identity=44.5414847161572, Blast_Score=194, Evalue=3e-50,
Organism=Saccharomyces cerevisiae, GI6319554, Length=404, Percent_Identity=32.9207920792079, Blast_Score=187, Evalue=4e-48,
Organism=Saccharomyces cerevisiae, GI6320854, Length=257, Percent_Identity=42.0233463035019, Blast_Score=181, Evalue=3e-46,
Organism=Saccharomyces cerevisiae, GI6325281, Length=314, Percent_Identity=35.9872611464968, Blast_Score=181, Evalue=5e-46,
Organism=Saccharomyces cerevisiae, GI6323736, Length=240, Percent_Identity=41.6666666666667, Blast_Score=181, Evalue=5e-46,
Organism=Saccharomyces cerevisiae, GI6321465, Length=269, Percent_Identity=39.4052044609665, Blast_Score=171, Evalue=3e-43,
Organism=Saccharomyces cerevisiae, GI6325431, Length=239, Percent_Identity=40.1673640167364, Blast_Score=168, Evalue=3e-42,
Organism=Saccharomyces cerevisiae, GI6325183, Length=291, Percent_Identity=35.3951890034364, Blast_Score=167, Evalue=4e-42,
Organism=Saccharomyces cerevisiae, GI6320887, Length=299, Percent_Identity=32.4414715719064, Blast_Score=144, Evalue=6e-35,
Organism=Drosophila melanogaster, GI17137560, Length=673, Percent_Identity=45.6166419019317, Blast_Score=593, Evalue=1e-169,
Organism=Drosophila melanogaster, GI161076486, Length=677, Percent_Identity=45.3471196454948, Blast_Score=593, Evalue=1e-169,
Organism=Drosophila melanogaster, GI161076488, Length=671, Percent_Identity=45.6035767511177, Blast_Score=592, Evalue=1e-169,
Organism=Drosophila melanogaster, GI19921202, Length=533, Percent_Identity=39.7748592870544, Blast_Score=376, Evalue=1e-104,
Organism=Drosophila melanogaster, GI281365776, Length=266, Percent_Identity=47.7443609022556, Blast_Score=261, Evalue=1e-69,
Organism=Drosophila melanogaster, GI24660075, Length=266, Percent_Identity=47.7443609022556, Blast_Score=261, Evalue=1e-69,
Organism=Drosophila melanogaster, GI45552965, Length=266, Percent_Identity=47.7443609022556, Blast_Score=261, Evalue=1e-69,
Organism=Drosophila melanogaster, GI24656825, Length=483, Percent_Identity=34.1614906832298, Blast_Score=250, Evalue=2e-66,
Organism=Drosophila melanogaster, GI24656820, Length=502, Percent_Identity=32.8685258964143, Blast_Score=242, Evalue=6e-64,
Organism=Drosophila melanogaster, GI21355121, Length=509, Percent_Identity=32.0235756385069, Blast_Score=233, Evalue=3e-61,
Organism=Drosophila melanogaster, GI281363136, Length=504, Percent_Identity=32.9365079365079, Blast_Score=227, Evalue=2e-59,
Organism=Drosophila melanogaster, GI78707192, Length=504, Percent_Identity=32.9365079365079, Blast_Score=227, Evalue=2e-59,
Organism=Drosophila melanogaster, GI18860063, Length=227, Percent_Identity=46.6960352422907, Blast_Score=218, Evalue=1e-56,
Organism=Drosophila melanogaster, GI281361487, Length=241, Percent_Identity=45.2282157676349, Blast_Score=217, Evalue=2e-56,
Organism=Drosophila melanogaster, GI24649446, Length=232, Percent_Identity=45.6896551724138, Blast_Score=216, Evalue=6e-56,
Organism=Drosophila melanogaster, GI19920408, Length=246, Percent_Identity=43.9024390243902, Blast_Score=212, Evalue=9e-55,
Organism=Drosophila melanogaster, GI24651451, Length=266, Percent_Identity=42.8571428571429, Blast_Score=211, Evalue=1e-54,
Organism=Drosophila melanogaster, GI24652279, Length=206, Percent_Identity=49.0291262135922, Blast_Score=209, Evalue=7e-54,
Organism=Drosophila melanogaster, GI17137738, Length=300, Percent_Identity=39.6666666666667, Blast_Score=205, Evalue=1e-52,
Organism=Drosophila melanogaster, GI17738151, Length=239, Percent_Identity=43.9330543933054, Blast_Score=203, Evalue=3e-52,
Organism=Drosophila melanogaster, GI24640100, Length=265, Percent_Identity=40.377358490566, Blast_Score=202, Evalue=5e-52,
Organism=Drosophila melanogaster, GI24663015, Length=267, Percent_Identity=40.8239700374532, Blast_Score=202, Evalue=1e-51,
Organism=Drosophila melanogaster, GI24658770, Length=221, Percent_Identity=47.5113122171946, Blast_Score=190, Evalue=3e-48,
Organism=Drosophila melanogaster, GI24665814, Length=231, Percent_Identity=46.3203463203463, Blast_Score=189, Evalue=4e-48,
Organism=Drosophila melanogaster, GI28574878, Length=233, Percent_Identity=46.7811158798283, Blast_Score=189, Evalue=4e-48,
Organism=Drosophila melanogaster, GI24639391, Length=253, Percent_Identity=41.897233201581, Blast_Score=185, Evalue=8e-47,
Organism=Drosophila melanogaster, GI17864540, Length=412, Percent_Identity=33.0097087378641, Blast_Score=175, Evalue=8e-44,
Organism=Drosophila melanogaster, GI28573010, Length=407, Percent_Identity=34.1523341523341, Blast_Score=175, Evalue=1e-43,
Organism=Drosophila melanogaster, GI20129423, Length=279, Percent_Identity=36.2007168458781, Blast_Score=172, Evalue=5e-43,
Organism=Drosophila melanogaster, GI18859657, Length=238, Percent_Identity=42.8571428571429, Blast_Score=172, Evalue=6e-43,
Organism=Drosophila melanogaster, GI24644145, Length=296, Percent_Identity=35.472972972973, Blast_Score=171, Evalue=1e-42,
Organism=Drosophila melanogaster, GI281360136, Length=278, Percent_Identity=36.3309352517986, Blast_Score=163, Evalue=4e-40,
Organism=Drosophila melanogaster, GI24644411, Length=278, Percent_Identity=36.3309352517986, Blast_Score=163, Evalue=4e-40,
Organism=Drosophila melanogaster, GI281360146, Length=278, Percent_Identity=36.3309352517986, Blast_Score=163, Evalue=4e-40,
Organism=Drosophila melanogaster, GI281360138, Length=278, Percent_Identity=36.3309352517986, Blast_Score=163, Evalue=4e-40,
Organism=Drosophila melanogaster, GI281360142, Length=278, Percent_Identity=36.3309352517986, Blast_Score=163, Evalue=4e-40,
Organism=Drosophila melanogaster, GI21357333, Length=278, Percent_Identity=36.3309352517986, Blast_Score=163, Evalue=4e-40,
Organism=Drosophila melanogaster, GI281360144, Length=278, Percent_Identity=36.3309352517986, Blast_Score=163, Evalue=4e-40,
Organism=Drosophila melanogaster, GI281360140, Length=278, Percent_Identity=36.3309352517986, Blast_Score=163, Evalue=4e-40,
Organism=Drosophila melanogaster, GI24581396, Length=291, Percent_Identity=36.0824742268041, Blast_Score=158, Evalue=1e-38,
Organism=Drosophila melanogaster, GI20129529, Length=241, Percent_Identity=39.0041493775934, Blast_Score=157, Evalue=2e-38,
Organism=Drosophila melanogaster, GI28571849, Length=289, Percent_Identity=33.9100346020761, Blast_Score=140, Evalue=2e-33,
Organism=Drosophila melanogaster, GI28571847, Length=289, Percent_Identity=33.9100346020761, Blast_Score=140, Evalue=2e-33,
Organism=Drosophila melanogaster, GI45554047, Length=164, Percent_Identity=43.2926829268293, Blast_Score=135, Evalue=9e-32,
Organism=Drosophila melanogaster, GI24639486, Length=227, Percent_Identity=33.920704845815, Blast_Score=132, Evalue=7e-31,
Organism=Drosophila melanogaster, GI28573181, Length=199, Percent_Identity=28.1407035175879, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI20129417, Length=211, Percent_Identity=27.4881516587678, Blast_Score=69, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24583262, Length=211, Percent_Identity=27.4881516587678, Blast_Score=69, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009010
- InterPro:   IPR003593
- InterPro:   IPR005938
- InterPro:   IPR003959
- InterPro:   IPR003960
- InterPro:   IPR003338
- InterPro:   IPR004201
- InterPro:   IPR015415 [H]

Pfam domain/function: PF00004 AAA; PF02933 CDC48_2; PF02359 CDC48_N; PF09336 Vps4_C [H]

EC number: 3.4.24.- [C]

Molecular weight: Translated: 77910; Mature: 77779

Theoretical pI: Translated: 7.96; Mature: 7.96

Prosite motif: PS00674 AAA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure: 

>Translated Secondary Structure
MTVATREHTRTLRAAESLGKDLGRGLARMDPADMKRLGAHVGDIVTLSGKRRSAAKVMPS
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCEEEECCCCCHHHHCCCC
YPDARGRGILQIDGVTRANTGVQLDEPVKLTLAPARHAEKVVLAPLEFTPAQRDLAYIGT
CCCCCCCEEEEECCCEECCCCCCCCCCCEEEECCCCCCCEEEEECCCCCCCHHHHHHHHH
LLDGLPVVKGDRVRALLFGSRTADFRVVETTPVGAVVIHPNTLLEVAKAPEKEKVTHERA
HHCCCCCCCCCCEEEEEECCCCCCEEEEEECCCCEEEECCHHHHHHHCCCCHHHHHHHHH
RAVSYEDVGGLKRELGRIREIVELPLRYPEVFERLGIDAPKGVLLYGPPGCGKTLIARAV
HHCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCEEEECCCCCCHHHHHHHH
AHETAAAFFTITGPEIMHKFYGESEAHLRQIFDEAQRRAPAIIFVDEIDAIAPRRENVQG
HHHHHHEEEEECCHHHHHHHCCCCHHHHHHHHHHHHHCCCEEEEEECCHHCCCCCCCCCH
EVEKRVVAQLLSLMDGLAQRRHVIVLAATNIPNVLDPALRRPGRFDREIAISIPDRTARK
HHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCHHHHHHHHCCCCCCCEEEEECCCHHHHH
EILAIHSRGMPLAEDVDLDHLAAVTHGFVGADLQALCREAAMLCLRRLIPHIDFASAEIP
HHHHHHCCCCCCHHCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCC
YDELIQVQVTMADFQAALHEVGPSAIREVFVETPDVGWKDVGGLGQLKQRLIEAVEWPLR
HHHHEEEEEHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCC
YPEEFARAKVRPPKGVLLSGPPGCGKTLMAKAAAHESQVNFISVKGPALLSKFVGESERG
CCHHHHHCCCCCCCCEEECCCCCCCHHHHHHHHHCCCCCCEEEECCHHHHHHHHCCCCCH
VRETFQKARQAAPCIIFFDEIDSLVPTRSAGGMDERVTERVVSQFLAEMDGIEELTGVLV
HHHHHHHHHHCCCEEEEHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHCCEEE
LAATNRADLLDPALLRPGRFDLLVDVPLPDREARRDIFQVHLRDKPVEKDLDLGGLAARS
EEECCCCHHCCHHHCCCCCEEEEEECCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCHHCC
ESFSGADIQAVCNQAAWEAVRHVISGKGKRLVITSESLLKAIRGHKEARRP
CCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEECHHHHHHHHCCHHHCCC
>Mature Secondary Structure 
TVATREHTRTLRAAESLGKDLGRGLARMDPADMKRLGAHVGDIVTLSGKRRSAAKVMPS
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCEEEECCCCCHHHHCCCC
YPDARGRGILQIDGVTRANTGVQLDEPVKLTLAPARHAEKVVLAPLEFTPAQRDLAYIGT
CCCCCCCEEEEECCCEECCCCCCCCCCCEEEECCCCCCCEEEEECCCCCCCHHHHHHHHH
LLDGLPVVKGDRVRALLFGSRTADFRVVETTPVGAVVIHPNTLLEVAKAPEKEKVTHERA
HHCCCCCCCCCCEEEEEECCCCCCEEEEEECCCCEEEECCHHHHHHHCCCCHHHHHHHHH
RAVSYEDVGGLKRELGRIREIVELPLRYPEVFERLGIDAPKGVLLYGPPGCGKTLIARAV
HHCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCEEEECCCCCCHHHHHHHH
AHETAAAFFTITGPEIMHKFYGESEAHLRQIFDEAQRRAPAIIFVDEIDAIAPRRENVQG
HHHHHHEEEEECCHHHHHHHCCCCHHHHHHHHHHHHHCCCEEEEEECCHHCCCCCCCCCH
EVEKRVVAQLLSLMDGLAQRRHVIVLAATNIPNVLDPALRRPGRFDREIAISIPDRTARK
HHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCHHHHHHHHCCCCCCCEEEEECCCHHHHH
EILAIHSRGMPLAEDVDLDHLAAVTHGFVGADLQALCREAAMLCLRRLIPHIDFASAEIP
HHHHHHCCCCCCHHCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCC
YDELIQVQVTMADFQAALHEVGPSAIREVFVETPDVGWKDVGGLGQLKQRLIEAVEWPLR
HHHHEEEEEHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCC
YPEEFARAKVRPPKGVLLSGPPGCGKTLMAKAAAHESQVNFISVKGPALLSKFVGESERG
CCHHHHHCCCCCCCCEEECCCCCCCHHHHHHHHHCCCCCCEEEECCHHHHHHHHCCCCCH
VRETFQKARQAAPCIIFFDEIDSLVPTRSAGGMDERVTERVVSQFLAEMDGIEELTGVLV
HHHHHHHHHHCCCEEEEHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHCCEEE
LAATNRADLLDPALLRPGRFDLLVDVPLPDREARRDIFQVHLRDKPVEKDLDLGGLAARS
EEECCCCHHCCHHHCCCCCEEEEEECCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCHHCC
ESFSGADIQAVCNQAAWEAVRHVISGKGKRLVITSESLLKAIRGHKEARRP
CCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEECHHHHHHHHCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Metalloendopeptidases [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9389475 [H]