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The map label for this gene is dctB [H]

Identifier: 108758721

GI number: 108758721

Start: 1057351

End: 1058355

Strand: Reverse

Name: dctB [H]

Synonym: MXAN_0928

Alternate gene names: 108758721

Gene position: 1058355-1057351 (Counterclockwise)

Preceding gene: 108760164

Following gene: 108763798

Centisome position: 11.58

GC content: 70.95

Gene sequence:

>1005_bases
GTGATGACGCTGCGAGCGAGGGTGATGCTGATGTCGGCGGTGGCACAGCGGCGCGGAACACTGCGGCGCGCCTTCGACAC
GCTCCAGGGCCCCACCGTGAATGGCGTGCGGCTTCGCGCGCCGCGGTCCTCCACACGGGAGGCGGCGCTGCTGGAGGAGA
CGGTCCGCGAACGGACCGCGGCGCTGGAGGCGGCCAACGTCAAGCTGTCCCGCAGCCTGGAGCAGCTGCGCGCCACCCAG
GCGCAGCTGCTGTTCGCGGATCGACTGATTGCGCTGGGCCGCATCGCCGCGGGCGTGGGACACGAAATCAACAACCCGCT
GGCCTTCATCCTCAGCAACCTGGAGTACATCCACCAGGAGCTGCAGCAGAAGGAGCACCTGTCCGAGCAGGACCGGCAGG
AGGTGCTGGAGGCGCTGGCGGAGACGCGCGACGGAGCAGAGCGCATCCGCCTCATCGTCCGGGACCTGCAGACGCTGTCA
CGCGCGGAGGACGTGGGCACGGGCCCGTCGGACCTGGGCTCGGTGGTGCGCACGGCGGCGAAGATGGCCATGCACGAGCT
GCGGCACCGCGCGCGGCTGGTGGTGGAGTGTGAGGGCCTGCCGCCGGTCCAGGGCAATGGCGCGCGGCTGGGTCAGGTGT
TCCTCAACCTGCTGCTCAACGCGGCGCAGTCCATCGTCCCCGGCGAGGTGGAGAAGAACGAGGTCCACATCGTCGCCTGC
GAGTCGAAGGCCGGACGGGTGGCGGTGGAGGTGCGCGACACCGGCTGCGGCATTTCCCCGGAGCATCGCGAGCGCATCTT
CGACCCCTTCTTCACCACCAAGCCCCTGGGCGTGGGCACGGGCCTGGGGCTGGCGGTATGCCATGGCATCGTGACGTCGC
TGGGCGGCACCCTGACGGTGGAGAGCGCCCCGGTGCGGGGCAGCATCTTCCGCGTCACGTTGCCCGTGGCCGGCGCCTTC
GCCCAGGCGCCTCGCGCTTCGCAGCAAGCGGACGCGGTGGCCTGA

Upstream 100 bases:

>100_bases
TCCGTCCCTTGCCCCTGACCGCCATGACAGTGTTGACTACGCGGGTCTGTCACGACTCGGGGATTTTCCACGAACAGACA
CCACACCGCTGGAGCCGGAC

Downstream 100 bases:

>100_bases
GCGACTCCGGCGCCAGGCTCGCGTCGTACGGCGTCATCCCCTGCATCGGCGGCGCGTAGAGGTGCAGGGACACCGCCCCG
TGGCGGGACGCATTGTCGAT

Product: sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 334; Mature: 334

Protein sequence:

>334_residues
MMTLRARVMLMSAVAQRRGTLRRAFDTLQGPTVNGVRLRAPRSSTREAALLEETVRERTAALEAANVKLSRSLEQLRATQ
AQLLFADRLIALGRIAAGVGHEINNPLAFILSNLEYIHQELQQKEHLSEQDRQEVLEALAETRDGAERIRLIVRDLQTLS
RAEDVGTGPSDLGSVVRTAAKMAMHELRHRARLVVECEGLPPVQGNGARLGQVFLNLLLNAAQSIVPGEVEKNEVHIVAC
ESKAGRVAVEVRDTGCGISPEHRERIFDPFFTTKPLGVGTGLGLAVCHGIVTSLGGTLTVESAPVRGSIFRVTLPVAGAF
AQAPRASQQADAVA

Sequences:

>Translated_334_residues
MMTLRARVMLMSAVAQRRGTLRRAFDTLQGPTVNGVRLRAPRSSTREAALLEETVRERTAALEAANVKLSRSLEQLRATQ
AQLLFADRLIALGRIAAGVGHEINNPLAFILSNLEYIHQELQQKEHLSEQDRQEVLEALAETRDGAERIRLIVRDLQTLS
RAEDVGTGPSDLGSVVRTAAKMAMHELRHRARLVVECEGLPPVQGNGARLGQVFLNLLLNAAQSIVPGEVEKNEVHIVAC
ESKAGRVAVEVRDTGCGISPEHRERIFDPFFTTKPLGVGTGLGLAVCHGIVTSLGGTLTVESAPVRGSIFRVTLPVAGAF
AQAPRASQQADAVA
>Mature_334_residues
MMTLRARVMLMSAVAQRRGTLRRAFDTLQGPTVNGVRLRAPRSSTREAALLEETVRERTAALEAANVKLSRSLEQLRATQ
AQLLFADRLIALGRIAAGVGHEINNPLAFILSNLEYIHQELQQKEHLSEQDRQEVLEALAETRDGAERIRLIVRDLQTLS
RAEDVGTGPSDLGSVVRTAAKMAMHELRHRARLVVECEGLPPVQGNGARLGQVFLNLLLNAAQSIVPGEVEKNEVHIVAC
ESKAGRVAVEVRDTGCGISPEHRERIFDPFFTTKPLGVGTGLGLAVCHGIVTSLGGTLTVESAPVRGSIFRVTLPVAGAF
AQAPRASQQADAVA

Specific function: Member of the two-component regulatory system dctB/dctD involved in the transport of C4-dicarboxylates. DctB functions as a membrane-associated protein kinase that phosphorylates dctD in response to environmental signals [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1790436, Length=249, Percent_Identity=33.7349397590361, Blast_Score=116, Evalue=2e-27,
Organism=Escherichia coli, GI1788549, Length=242, Percent_Identity=30.5785123966942, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI145693157, Length=318, Percent_Identity=27.3584905660377, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI87081816, Length=126, Percent_Identity=35.7142857142857, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1786783, Length=261, Percent_Identity=27.5862068965517, Blast_Score=65, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR017055
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 36086; Mature: 36086

Theoretical pI: Translated: 8.68; Mature: 8.68

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMTLRARVMLMSAVAQRRGTLRRAFDTLQGPTVNGVRLRAPRSSTREAALLEETVRERTA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHH
ALEAANVKLSRSLEQLRATQAQLLFADRLIALGRIAAGVGHEINNPLAFILSNLEYIHQE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
LQQKEHLSEQDRQEVLEALAETRDGAERIRLIVRDLQTLSRAEDVGTGPSDLGSVVRTAA
HHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
KMAMHELRHRARLVVECEGLPPVQGNGARLGQVFLNLLLNAAQSIVPGEVEKNEVHIVAC
HHHHHHHHHHHEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEE
ESKAGRVAVEVRDTGCGISPEHRERIFDPFFTTKPLGVGTGLGLAVCHGIVTSLGGTLTV
CCCCCEEEEEEECCCCCCCHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHCCCEEEE
ESAPVRGSIFRVTLPVAGAFAQAPRASQQADAVA
ECCCCCCCEEEEEECHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MMTLRARVMLMSAVAQRRGTLRRAFDTLQGPTVNGVRLRAPRSSTREAALLEETVRERTA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHH
ALEAANVKLSRSLEQLRATQAQLLFADRLIALGRIAAGVGHEINNPLAFILSNLEYIHQE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
LQQKEHLSEQDRQEVLEALAETRDGAERIRLIVRDLQTLSRAEDVGTGPSDLGSVVRTAA
HHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
KMAMHELRHRARLVVECEGLPPVQGNGARLGQVFLNLLLNAAQSIVPGEVEKNEVHIVAC
HHHHHHHHHHHEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEE
ESKAGRVAVEVRDTGCGISPEHRERIFDPFFTTKPLGVGTGLGLAVCHGIVTSLGGTLTV
CCCCCEEEEEEECCCCCCCHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHCCCEEEE
ESAPVRGSIFRVTLPVAGAFAQAPRASQQADAVA
ECCCCCCCEEEEEECHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 2134335; 2793824; 11481431; 2551890; 2695394 [H]