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The map label for this gene is mdtA [H]

Identifier: 108758668

GI number: 108758668

Start: 4718454

End: 4719611

Strand: Reverse

Name: mdtA [H]

Synonym: MXAN_3922

Alternate gene names: 108758668

Gene position: 4719611-4718454 (Counterclockwise)

Preceding gene: 108758392

Following gene: 108758630

Centisome position: 51.64

GC content: 72.54

Gene sequence:

>1158_bases
GTGGATGCCGCGGCGCCCGACGCCGCGGCGCGAGGCGGGCGCTGGCCCTGGGTGTTCGCCGCCTTGCTCCTGGTGCTGCT
GGGGCTCGGCGTGGCGCCACGGTTGGAGCGGTCGCGCGCGTTGGATCGGCGTGAAGCGGAAGCCCGTCTGCCGCCGCTCG
TGGCCACCGCGCGCGTGACGCGGTCCGAGCCGAAGGCGGAGCTCACGTTGCCAGGGACGGTCCTTCCCAGTCAGCGCGCG
TCACTGCACGCCCGCATCAATGGCTTCGTGGGACGCATCCACGTCGACCTGGGCGACCGGGTCCGCGCGGGCCAGTTGCT
GGCGGAGCTTGAAGCGCCCGAGCTCCAGGCGGAGTGTCACCGGGCCCGGGCGCGCCTGGATGAGACGGAGCGGAACCTGG
AGCTCGCTCGCGCGTCCGCGCGGCGCGGGCAGATTCTCGCGGGAGAGGGCAACGTCAGCCACGAGGTGGCGGAGGAGGCG
CGGGCGCGGGCCAACTCCGCGGAGGCTTCGCTGAAGAGCGCGAAGGCGGAGGTGGAGCGCCTCGAAGCGTTGTACGCATT
TCGCCGCGTGGTGGCGCCGTTTGATGGTGTCATCGTGCGTCGCAACGTGGACCGGGGAGCGCTGGTCACCGCGGGCAGTG
GCAGCGGAATGACGAGCCTGTTCGAACTCGCGCAGACGCACACGCTGAAGGTCTACGTGGACGTGCCGCAGTCCCTCGCC
CATGACATCCGGCCGGGGCTCGAGGCGCGGATCTTCACGCTGGATGCGCCCGCGCGGGCGCTGCCGGGGCGCGTGGTGCG
GACCGCGGGGGTGTTGGACCCAGGGACCCGCACGCTCCTGACGGAGGTGCAGCTCGCCAACACAGAGGCGCTGTTCGCCG
GGTCATTCGTGCGCGTCCGGTTGCTCATCGAGCGCGAGGCTCCGCCCATGCTCATTCCGGCCAGCGCGCTGGCCGTGCGG
AGGGAGGGGCCCACGGTCCTCGTGGTGGGGGAGGCGAATGCCGTCCAGCAGCGCGTGGTCGTGCTGGGGCGTGACCTGGG
CGCGCATGTCGAGGTGATGGACGGATTGTCCGCGGAGGACAGGGTGGTGCTGAGCCCACCGGACACCCTGGGCGATGGGC
GCGTGGTGCGCGTCGCGGAAGGGCGTGCCGCGCGCTAG

Upstream 100 bases:

>100_bases
TTCCCGTCGTTTACAGTCTGATGCAGGCGCGGCGGGCTGTCCGCGCGGCGGCCCCTGAACTCGAGCCCTCGGTGACAGCG
TGACGGAGCAGACCCCTGGC

Downstream 100 bases:

>100_bases
TTCGCGTGGAGCTCAGCAAAATCGGATAGGGCTGCGATGTCGGTCAGCCTTGATATGCTGTGCGGACTGGAGACTTCGAT
GAAGCGTTTTCTGTGGCTGT

Product: RND family efflux transporter MFP subunit

Products: NA

Alternate protein names: Multidrug transporter mdtA [H]

Number of amino acids: Translated: 385; Mature: 385

Protein sequence:

>385_residues
MDAAAPDAAARGGRWPWVFAALLLVLLGLGVAPRLERSRALDRREAEARLPPLVATARVTRSEPKAELTLPGTVLPSQRA
SLHARINGFVGRIHVDLGDRVRAGQLLAELEAPELQAECHRARARLDETERNLELARASARRGQILAGEGNVSHEVAEEA
RARANSAEASLKSAKAEVERLEALYAFRRVVAPFDGVIVRRNVDRGALVTAGSGSGMTSLFELAQTHTLKVYVDVPQSLA
HDIRPGLEARIFTLDAPARALPGRVVRTAGVLDPGTRTLLTEVQLANTEALFAGSFVRVRLLIEREAPPMLIPASALAVR
REGPTVLVVGEANAVQQRVVVLGRDLGAHVEVMDGLSAEDRVVLSPPDTLGDGRVVRVAEGRAAR

Sequences:

>Translated_385_residues
MDAAAPDAAARGGRWPWVFAALLLVLLGLGVAPRLERSRALDRREAEARLPPLVATARVTRSEPKAELTLPGTVLPSQRA
SLHARINGFVGRIHVDLGDRVRAGQLLAELEAPELQAECHRARARLDETERNLELARASARRGQILAGEGNVSHEVAEEA
RARANSAEASLKSAKAEVERLEALYAFRRVVAPFDGVIVRRNVDRGALVTAGSGSGMTSLFELAQTHTLKVYVDVPQSLA
HDIRPGLEARIFTLDAPARALPGRVVRTAGVLDPGTRTLLTEVQLANTEALFAGSFVRVRLLIEREAPPMLIPASALAVR
REGPTVLVVGEANAVQQRVVVLGRDLGAHVEVMDGLSAEDRVVLSPPDTLGDGRVVRVAEGRAAR
>Mature_385_residues
MDAAAPDAAARGGRWPWVFAALLLVLLGLGVAPRLERSRALDRREAEARLPPLVATARVTRSEPKAELTLPGTVLPSQRA
SLHARINGFVGRIHVDLGDRVRAGQLLAELEAPELQAECHRARARLDETERNLELARASARRGQILAGEGNVSHEVAEEA
RARANSAEASLKSAKAEVERLEALYAFRRVVAPFDGVIVRRNVDRGALVTAGSGSGMTSLFELAQTHTLKVYVDVPQSLA
HDIRPGLEARIFTLDAPARALPGRVVRTAGVLDPGTRTLLTEVQLANTEALFAGSFVRVRLLIEREAPPMLIPASALAVR
REGPTVLVVGEANAVQQRVVVLGRDLGAHVEVMDGLSAEDRVVLSPPDTLGDGRVVRVAEGRAAR

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI87082036, Length=342, Percent_Identity=27.4853801169591, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI1786668, Length=344, Percent_Identity=27.3255813953488, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1789929, Length=345, Percent_Identity=26.0869565217391, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1789665, Length=342, Percent_Identity=26.6081871345029, Blast_Score=80, Evalue=3e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022824
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 41303; Mature: 41303

Theoretical pI: Translated: 10.17; Mature: 10.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDAAAPDAAARGGRWPWVFAALLLVLLGLGVAPRLERSRALDRREAEARLPPLVATARVT
CCCCCCCHHHCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHH
RSEPKAELTLPGTVLPSQRASLHARINGFVGRIHVDLGDRVRAGQLLAELEAPELQAECH
CCCCCCEEEECCCCCCCCHHHHHHEEECEEEEEEECCCCCCHHHHHHHHCCCCHHHHHHH
RARARLDETERNLELARASARRGQILAGEGNVSHEVAEEARARANSAEASLKSAKAEVER
HHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHH
LEALYAFRRVVAPFDGVIVRRNVDRGALVTAGSGSGMTSLFELAQTHTLKVYVDVPQSLA
HHHHHHHHHHHCCCCCEEEEECCCCCEEEEECCCCCHHHHHHHHHCEEEEEEEECCHHHH
HDIRPGLEARIFTLDAPARALPGRVVRTAGVLDPGTRTLLTEVQLANTEALFAGSFVRVR
HHCCCCCCEEEEEECCCCHHCCCHHHHHCCCCCCCCHHHHHHEECCCCCHHHCCCEEEEE
LLIEREAPPMLIPASALAVRREGPTVLVVGEANAVQQRVVVLGRDLGAHVEVMDGLSAED
EEEECCCCCEEECHHHHEEECCCCEEEEEECCHHHHHHHHHEECCCCCCCHHHCCCCCCC
RVVLSPPDTLGDGRVVRVAEGRAAR
EEEECCCCCCCCCCEEEECCCCCCC
>Mature Secondary Structure
MDAAAPDAAARGGRWPWVFAALLLVLLGLGVAPRLERSRALDRREAEARLPPLVATARVT
CCCCCCCHHHCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHH
RSEPKAELTLPGTVLPSQRASLHARINGFVGRIHVDLGDRVRAGQLLAELEAPELQAECH
CCCCCCEEEECCCCCCCCHHHHHHEEECEEEEEEECCCCCCHHHHHHHHCCCCHHHHHHH
RARARLDETERNLELARASARRGQILAGEGNVSHEVAEEARARANSAEASLKSAKAEVER
HHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHH
LEALYAFRRVVAPFDGVIVRRNVDRGALVTAGSGSGMTSLFELAQTHTLKVYVDVPQSLA
HHHHHHHHHHHCCCCCEEEEECCCCCEEEEECCCCCHHHHHHHHHCEEEEEEEECCHHHH
HDIRPGLEARIFTLDAPARALPGRVVRTAGVLDPGTRTLLTEVQLANTEALFAGSFVRVR
HHCCCCCCEEEEEECCCCHHCCCHHHHHCCCCCCCCHHHHHHEECCCCCHHHCCCEEEEE
LLIEREAPPMLIPASALAVRREGPTVLVVGEANAVQQRVVVLGRDLGAHVEVMDGLSAED
EEEECCCCCEEECHHHHEEECCCCEEEEEECCHHHHHHHHHEECCCCCCCHHHCCCCCCC
RVVLSPPDTLGDGRVVRVAEGRAAR
EEEECCCCCCCCCCEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA