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The map label for this gene is plsC [H]

Identifier: 108758660

GI number: 108758660

Start: 1097342

End: 1098067

Strand: Direct

Name: plsC [H]

Synonym: MXAN_0955

Alternate gene names: 108758660

Gene position: 1097342-1098067 (Clockwise)

Preceding gene: 108759992

Following gene: 108762615

Centisome position: 12.01

GC content: 67.22

Gene sequence:

>726_bases
ATGAAGTACGCCGTCACGCTCTGGTTCTGGGTCGTCTTCCTGCTCACCGCCCCGGTGCTGTTCACCCTGGGCGCGCTGCT
GCTCATCGTCACGTACCCGTTCGACCGGGACCGGCGGCTCTTGCACTCATTGGTCTGTCGTTGGTGCTATGGCCTGTGGC
TGCACGCGTCCCCAGGCTGGCGCACGCGAATCGAAGGCCGTGAGCTCATTCCGCCCGGGCCCTGTGTGATGGTGGTCAAC
CACCAGTCCGCGGCGGACATCCTCGCCGTCATGGGCCTGTTCCGTCCCTACAAGTTCGTGGCGAAGGCGTCGCTGTTCTC
GCTGCCCCTGGTGGGGTGGATGATGACGCTGCTGGCCTACGTGCCCATTGTCCGGGGCTCGTCCACCGCCATGAACCAGC
TCCTGGATCCGTGCCGGCGCTGGCTTCGTCGTGGCATGCCGGTGCTCATCTTCCCGGAGGGGACGTACTCCAAGGGCGGG
CAGTTGCTGCCCTTCAAGCGGGGCGCCTTCCAGCTCGCGCTGGAGGAGCATGTGCCGGTGGTGCCCGTGGTGGTGGAGGG
CACGCCAGGGCTGCTGGATGGAGACGGCCCCTGGATGAGTCCCACCGCCTCCATCCGCGTGCGCGTGCTTCCCGCGCTGC
CGCCCGAGTCCTTCAGTCCGGACTCACAGGCGTTGGCCACGCAGGTTCGCGCGCTGTTCGAGCAGACGTTGGCGAAGACG
GGCTGA

Upstream 100 bases:

>100_bases
GGCCGGTCGGCTGGATGGGAGGGGCGCGGCCGTGGGAGTGCGGGGCCGTCAGGAGGGGAGCGTGGGATGGGCCCGAAGGT
GGTATGCCTGGGGCCTCGCC

Downstream 100 bases:

>100_bases
GTGCCCCCGCGCTCGCGCCTGGCCACGGTCAAGCCCACCCTGGTGCAAATAATGGGGGGCTGAAACACTGACACAATCCA
ATACAGGATGGGTGAGTCCT

Product: putative 1-acyl-sn-glycerol-3-phosphate acyltransferase

Products: NA

Alternate protein names: 1-AGP acyltransferase; 1-AGPAT; Lysophosphatidic acid acyltransferase; LPAAT; Phosphatidic acid synthase; PA synthase [H]

Number of amino acids: Translated: 241; Mature: 241

Protein sequence:

>241_residues
MKYAVTLWFWVVFLLTAPVLFTLGALLLIVTYPFDRDRRLLHSLVCRWCYGLWLHASPGWRTRIEGRELIPPGPCVMVVN
HQSAADILAVMGLFRPYKFVAKASLFSLPLVGWMMTLLAYVPIVRGSSTAMNQLLDPCRRWLRRGMPVLIFPEGTYSKGG
QLLPFKRGAFQLALEEHVPVVPVVVEGTPGLLDGDGPWMSPTASIRVRVLPALPPESFSPDSQALATQVRALFEQTLAKT
G

Sequences:

>Translated_241_residues
MKYAVTLWFWVVFLLTAPVLFTLGALLLIVTYPFDRDRRLLHSLVCRWCYGLWLHASPGWRTRIEGRELIPPGPCVMVVN
HQSAADILAVMGLFRPYKFVAKASLFSLPLVGWMMTLLAYVPIVRGSSTAMNQLLDPCRRWLRRGMPVLIFPEGTYSKGG
QLLPFKRGAFQLALEEHVPVVPVVVEGTPGLLDGDGPWMSPTASIRVRVLPALPPESFSPDSQALATQVRALFEQTLAKT
G
>Mature_241_residues
MKYAVTLWFWVVFLLTAPVLFTLGALLLIVTYPFDRDRRLLHSLVCRWCYGLWLHASPGWRTRIEGRELIPPGPCVMVVN
HQSAADILAVMGLFRPYKFVAKASLFSLPLVGWMMTLLAYVPIVRGSSTAMNQLLDPCRRWLRRGMPVLIFPEGTYSKGG
QLLPFKRGAFQLALEEHVPVVPVVVEGTPGLLDGDGPWMSPTASIRVRVLPALPPESFSPDSQALATQVRALFEQTLAKT
G

Specific function: Converts lysophosphatidic acid (LPA) into phosphatidic acid by incorporating an acyl moiety at the 2 position. This enzyme can utilize either acyl-CoA or acyl-ACP as the fatty acyl donor [H]

COG id: COG0204

COG function: function code I; 1-acyl-sn-glycerol-3-phosphate acyltransferase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI6041665, Length=156, Percent_Identity=38.4615384615385, Blast_Score=93, Evalue=2e-19,
Organism=Homo sapiens, GI5453718, Length=177, Percent_Identity=35.0282485875706, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI15100175, Length=177, Percent_Identity=35.0282485875706, Blast_Score=84, Evalue=2e-16,
Organism=Escherichia coli, GI1789395, Length=170, Percent_Identity=29.4117647058824, Blast_Score=77, Evalue=7e-16,
Organism=Caenorhabditis elegans, GI17564032, Length=200, Percent_Identity=27.5, Blast_Score=83, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6320151, Length=188, Percent_Identity=32.4468085106383, Blast_Score=86, Evalue=6e-18,
Organism=Drosophila melanogaster, GI24641614, Length=202, Percent_Identity=30.1980198019802, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24641612, Length=202, Percent_Identity=30.1980198019802, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI281364648, Length=229, Percent_Identity=27.5109170305677, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24582856, Length=229, Percent_Identity=27.5109170305677, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24582854, Length=229, Percent_Identity=27.5109170305677, Blast_Score=74, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002123
- InterPro:   IPR004552 [H]

Pfam domain/function: PF01553 Acyltransferase [H]

EC number: =2.3.1.51 [H]

Molecular weight: Translated: 26857; Mature: 26857

Theoretical pI: Translated: 9.93; Mature: 9.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKYAVTLWFWVVFLLTAPVLFTLGALLLIVTYPFDRDRRLLHSLVCRWCYGLWLHASPGW
CCEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHEEECCCCC
RTRIEGRELIPPGPCVMVVNHQSAADILAVMGLFRPYKFVAKASLFSLPLVGWMMTLLAY
CEECCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VPIVRGSSTAMNQLLDPCRRWLRRGMPVLIFPEGTYSKGGQLLPFKRGAFQLALEEHVPV
HHHHCCCHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCEECCCCCCHHEEEHHCCCCE
VPVVVEGTPGLLDGDGPWMSPTASIRVRVLPALPPESFSPDSQALATQVRALFEQTLAKT
EEEEECCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHCC
G
C
>Mature Secondary Structure
MKYAVTLWFWVVFLLTAPVLFTLGALLLIVTYPFDRDRRLLHSLVCRWCYGLWLHASPGW
CCEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHEEECCCCC
RTRIEGRELIPPGPCVMVVNHQSAADILAVMGLFRPYKFVAKASLFSLPLVGWMMTLLAY
CEECCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VPIVRGSSTAMNQLLDPCRRWLRRGMPVLIFPEGTYSKGGQLLPFKRGAFQLALEEHVPV
HHHHCCCHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCEECCCCCCHHEEEHHCCCCE
VPVVVEGTPGLLDGDGPWMSPTASIRVRVLPALPPESFSPDSQALATQVRALFEQTLAKT
EEEEECCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHCC
G
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1557036; 9278503 [H]