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The map label for this gene is xseA [H]

Identifier: 108758486

GI number: 108758486

Start: 5829374

End: 5830876

Strand: Reverse

Name: xseA [H]

Synonym: MXAN_4647

Alternate gene names: 108758486

Gene position: 5830876-5829374 (Counterclockwise)

Preceding gene: 108763994

Following gene: 108757657

Centisome position: 63.8

GC content: 71.92

Gene sequence:

>1503_bases
GTGGTGCTGTCGGTGGGGGAGCTGACCCGCCAGCTCAAGCAGACGCTGGAGTCGCGCTTCGCTCGCGTCATCGTGCGCGG
CGAGGTGACGGGCTTCCGCGGGCCCAACGCGCGCGGCCACTGGTACTTCTCGCTGAAGGACGCGGGCGCGGCCATCGACA
CGAAGGTGTGGGCCTCCATGGCGGCCCGCTTGCGCTTCGCGCTGCGCGACGGCATGGAGGTGATTGCCGAAGGCAGCGTG
GACCTGTACGAGCCGCAGGGCCGCTACAGCCTCATCGTTCAGCGGCTGGAGCCGGTGGGCGAGGGCGCGCTGGCGCTGGC
CTTCGAGCAGCTCAAGGAGCGGCTGGCCCAGGAGGGACTCATTGGTCCCGGGCGTGTGCGGCCCCCCAGGCCGTTGCCCT
ACCTGCCTCGGCGGATTGGCGTGGTGACGAGCCGGACCGGCGCGGCGCTCCAGGACTTCCTGCGCGTGCTGCATTCGCGC
AACCCGCGGCAGAGCGTCCTGGTGGCGGATGCGCGCGTGCAGGGCGAAGGCTCCGCCGTGGAGGTGGCTCGCGCCATCGA
GCGGCTGGCTCGCACGGACGTGGACGTCATCGTGGTGACGCGCGGTGGTGGCTCGGTGGAGGACCTCTGGACCTTCAACG
AGGAGCGGGTGGCGCGCGCCATCTTCGCCTCGCCGGTGCCGGTGGTGTCCGCCATTGGCCACGAAATCGACTTCACCATC
TCCGACTTCGTGGCGGACCTGCGCGCGCCCACGCCCAGCGCCGCGGCGGAGCGCCTGGCGCCGGTGCTGGCCGACCTGGA
GCTGACGCTGGCCACGCAGGCGGGCCGTCTGCGGCGTGCCATGGAGCGCCGGGTGTTGGAGCTGCGCGAGGAGCAAGGGC
AGCTCGCGTCGCGGCTGGAGGACCCTCGGCGGGCCATCAACCACCAGCGGCTGCACCTGTCCGAGCAGGTGGAGTCGATG
ATGCGCGTGCTGCGGCCAGCCGTGCGGGGGCACCGCGAGGAGCTGCGGTCGCTGACCGAAAGGCTGCAGCGGGCGCGTCC
CCAGGCACGGCTGGGGGAGCAGCGGGCGCACCTGTTGAAGCTGGCCATGCGGCTGTCGGAGGCGGTGCGCGCAGGTGTGG
CGACGCGGCACGGGGCGCTGGCGACGGCACGGCTGGGGCTCGAGAGGGCGTCACCGGCGGCCCAGGTGTCCCGTGAGCGC
GCCCGGCTGGCCGCGCACCGGGCGCGGCTGCTGGCGCTCCAGCAAGGGGCCCTGGCGGATGCACAGAAGCGTTTCCAGCG
TCTGGAGGGACGTCTGGATGCCATGAGTCCGTTGAAGGTGATGTCCCGCGGTTATTCGGTGGTGTTCCGACAGCGCGATG
GCGCGGTGGTCCGCACTGGCGCGGATGTCCAGGTGGGAGAGCGCCTGGGGCTGAAGCTCGCGTCGAACGGGGCGAAGTCG
CTCGGGGGATGTGAAGAAATCGAAGCCACCGTCACGGCGGTGAAAGGGCCGGTGGACTGCTGA

Upstream 100 bases:

>100_bases
GGCGCCGCCGAAGCCTCCTCCGCCTCCGGTGGACGAGGACGGCACCTCGCTGCTGGGTCCGATGGAGGGCGCGCCGCCTC
CGCCGCCCAAGCCCGAGCGC

Downstream 100 bases:

>100_bases
CGGGCCACCCTCTAGAGTCCCGCGCCCCATGCGGGGAGGTGGATGGAAGTGGCGAAGTCGGACAAGGCGCCCAAGGCGGA
CAAGGTAGCGGAGGCCGAGG

Product: exodeoxyribonuclease VII large subunit

Products: NA

Alternate protein names: Exodeoxyribonuclease VII large subunit; Exonuclease VII large subunit [H]

Number of amino acids: Translated: 500; Mature: 500

Protein sequence:

>500_residues
MVLSVGELTRQLKQTLESRFARVIVRGEVTGFRGPNARGHWYFSLKDAGAAIDTKVWASMAARLRFALRDGMEVIAEGSV
DLYEPQGRYSLIVQRLEPVGEGALALAFEQLKERLAQEGLIGPGRVRPPRPLPYLPRRIGVVTSRTGAALQDFLRVLHSR
NPRQSVLVADARVQGEGSAVEVARAIERLARTDVDVIVVTRGGGSVEDLWTFNEERVARAIFASPVPVVSAIGHEIDFTI
SDFVADLRAPTPSAAAERLAPVLADLELTLATQAGRLRRAMERRVLELREEQGQLASRLEDPRRAINHQRLHLSEQVESM
MRVLRPAVRGHREELRSLTERLQRARPQARLGEQRAHLLKLAMRLSEAVRAGVATRHGALATARLGLERASPAAQVSRER
ARLAAHRARLLALQQGALADAQKRFQRLEGRLDAMSPLKVMSRGYSVVFRQRDGAVVRTGADVQVGERLGLKLASNGAKS
LGGCEEIEATVTAVKGPVDC

Sequences:

>Translated_500_residues
MVLSVGELTRQLKQTLESRFARVIVRGEVTGFRGPNARGHWYFSLKDAGAAIDTKVWASMAARLRFALRDGMEVIAEGSV
DLYEPQGRYSLIVQRLEPVGEGALALAFEQLKERLAQEGLIGPGRVRPPRPLPYLPRRIGVVTSRTGAALQDFLRVLHSR
NPRQSVLVADARVQGEGSAVEVARAIERLARTDVDVIVVTRGGGSVEDLWTFNEERVARAIFASPVPVVSAIGHEIDFTI
SDFVADLRAPTPSAAAERLAPVLADLELTLATQAGRLRRAMERRVLELREEQGQLASRLEDPRRAINHQRLHLSEQVESM
MRVLRPAVRGHREELRSLTERLQRARPQARLGEQRAHLLKLAMRLSEAVRAGVATRHGALATARLGLERASPAAQVSRER
ARLAAHRARLLALQQGALADAQKRFQRLEGRLDAMSPLKVMSRGYSVVFRQRDGAVVRTGADVQVGERLGLKLASNGAKS
LGGCEEIEATVTAVKGPVDC
>Mature_500_residues
MVLSVGELTRQLKQTLESRFARVIVRGEVTGFRGPNARGHWYFSLKDAGAAIDTKVWASMAARLRFALRDGMEVIAEGSV
DLYEPQGRYSLIVQRLEPVGEGALALAFEQLKERLAQEGLIGPGRVRPPRPLPYLPRRIGVVTSRTGAALQDFLRVLHSR
NPRQSVLVADARVQGEGSAVEVARAIERLARTDVDVIVVTRGGGSVEDLWTFNEERVARAIFASPVPVVSAIGHEIDFTI
SDFVADLRAPTPSAAAERLAPVLADLELTLATQAGRLRRAMERRVLELREEQGQLASRLEDPRRAINHQRLHLSEQVESM
MRVLRPAVRGHREELRSLTERLQRARPQARLGEQRAHLLKLAMRLSEAVRAGVATRHGALATARLGLERASPAAQVSRER
ARLAAHRARLLALQQGALADAQKRFQRLEGRLDAMSPLKVMSRGYSVVFRQRDGAVVRTGADVQVGERLGLKLASNGAKS
LGGCEEIEATVTAVKGPVDC

Specific function: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides [H]

COG id: COG1570

COG function: function code L; Exonuclease VII, large subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xseA family [H]

Homologues:

Organism=Escherichia coli, GI1788856, Length=481, Percent_Identity=36.3825363825364, Blast_Score=274, Evalue=1e-74,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003753
- InterPro:   IPR020579
- InterPro:   IPR004365 [H]

Pfam domain/function: PF02601 Exonuc_VII_L; PF01336 tRNA_anti [H]

EC number: =3.1.11.6 [H]

Molecular weight: Translated: 54940; Mature: 54940

Theoretical pI: Translated: 11.35; Mature: 11.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVLSVGELTRQLKQTLESRFARVIVRGEVTGFRGPNARGHWYFSLKDAGAAIDTKVWASM
CCCCHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHH
AARLRFALRDGMEVIAEGSVDLYEPQGRYSLIVQRLEPVGEGALALAFEQLKERLAQEGL
HHHHHHHHHHCHHHHHCCCCEEECCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCC
IGPGRVRPPRPLPYLPRRIGVVTSRTGAALQDFLRVLHSRNPRQSVLVADARVQGEGSAV
CCCCCCCCCCCCCCCCHHHCCEECCCCHHHHHHHHHHHCCCCCHHEEEEECEECCCCHHH
EVARAIERLARTDVDVIVVTRGGGSVEDLWTFNEERVARAIFASPVPVVSAIGHEIDFTI
HHHHHHHHHHHCCCCEEEEECCCCCHHHHHCCCHHHHHHHHHCCCCHHHHHCCCCCCCCH
SDFVADLRAPTPSAAAERLAPVLADLELTLATQAGRLRRAMERRVLELREEQGQLASRLE
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
DPRRAINHQRLHLSEQVESMMRVLRPAVRGHREELRSLTERLQRARPQARLGEQRAHLLK
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
LAMRLSEAVRAGVATRHGALATARLGLERASPAAQVSRERARLAAHRARLLALQQGALAD
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHH
AQKRFQRLEGRLDAMSPLKVMSRGYSVVFRQRDGAVVRTGADVQVGERLGLKLASNGAKS
HHHHHHHHHHHHCCCCHHHHHHCCCEEEEEECCCCEEECCCCCCHHHHHCCCHHCCCCCC
LGGCEEIEATVTAVKGPVDC
CCCHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MVLSVGELTRQLKQTLESRFARVIVRGEVTGFRGPNARGHWYFSLKDAGAAIDTKVWASM
CCCCHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHH
AARLRFALRDGMEVIAEGSVDLYEPQGRYSLIVQRLEPVGEGALALAFEQLKERLAQEGL
HHHHHHHHHHCHHHHHCCCCEEECCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCC
IGPGRVRPPRPLPYLPRRIGVVTSRTGAALQDFLRVLHSRNPRQSVLVADARVQGEGSAV
CCCCCCCCCCCCCCCCHHHCCEECCCCHHHHHHHHHHHCCCCCHHEEEEECEECCCCHHH
EVARAIERLARTDVDVIVVTRGGGSVEDLWTFNEERVARAIFASPVPVVSAIGHEIDFTI
HHHHHHHHHHHCCCCEEEEECCCCCHHHHHCCCHHHHHHHHHCCCCHHHHHCCCCCCCCH
SDFVADLRAPTPSAAAERLAPVLADLELTLATQAGRLRRAMERRVLELREEQGQLASRLE
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
DPRRAINHQRLHLSEQVESMMRVLRPAVRGHREELRSLTERLQRARPQARLGEQRAHLLK
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
LAMRLSEAVRAGVATRHGALATARLGLERASPAAQVSRERARLAAHRARLLALQQGALAD
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHH
AQKRFQRLEGRLDAMSPLKVMSRGYSVVFRQRDGAVVRTGADVQVGERLGLKLASNGAKS
HHHHHHHHHHHHCCCCHHHHHHCCCEEEEEECCCCEEECCCCCCHHHHHCCCHHCCCCCC
LGGCEEIEATVTAVKGPVDC
CCCHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA