| Definition | Myxococcus xanthus DK 1622 chromosome, complete genome. |
|---|---|
| Accession | NC_008095 |
| Length | 9,139,763 |
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The map label for this gene is cypB [H]
Identifier: 108758450
GI number: 108758450
Start: 1369030
End: 1369776
Strand: Reverse
Name: cypB [H]
Synonym: MXAN_1176
Alternate gene names: 108758450
Gene position: 1369776-1369030 (Counterclockwise)
Preceding gene: 108760207
Following gene: 108757894
Centisome position: 14.99
GC content: 67.87
Gene sequence:
>747_bases ATGCGGACCCAATTCCTGACGACTGTCCTCCTCTGCCTTACCCTCACCGCCTGCAAGGACTCCGACAAGAAGGAATCCAT GGGGGGTGGTACCCCGCCTTCCGCGACGACGCCGGCGAAGCCCACGGCGCCTTCCGCCGCCGAGGTGCCGGCCGCGGCGC CCCCCGCCGAGGCCGCCTCGGGTGAATGGACGAAGAAGGTCCAGGCGGGCCAGGACGTCTACGCCACCCTCGAAACGAAC CAGGGCGCCATCGTCGTGCGCCTCTTCTCCAAGGATGCCCCCAAGACGGTGGCCAACTTCGTGGGCCTGGCCACGGGCGA GAAGGCCTGGACGGACCCGAAGACGGGCCAGCGCGTGGAGGGCAAGCCGCTGTACGACGGCGTCATCTTCCACCGGGTGA TTCCGGGCTTCATGATTCAGGGCGGCGACCCCACGGGCACCGGCCGCGGCGACCCGGGCTACCGCTTCGAGGACGAGTTC CAGAGCGGCCGCACCTTCGACAAGAAGGGCCTGCTGGCCATGGCCAACGCCGGCCCCGGCACCAACGGCAGCCAGTTCTT CATCACCACCTCCACGCCGGACTACCTCAACAACCGTCACACCATCTTCGGTGAAGTGGTGTCGGGCTACGACGTGGTGG AGAAGATTTCCAACGTGCAGCGCGACCCGCGCGACAAGCCCCTGGAGCCGGTCGTCATCCAGAAGATCGCGATGAGCGAC CAGGCCCCGGCCGGCAGCGGGAACTGA
Upstream 100 bases:
>100_bases CAGACCTTACTGATTTTCACTCCCGGTATCTGACAGATGCCGACCGATGACCCCGTAAGCCCCTGGAATCCATTGGAAAA GGGGCTAAGGTCCGCGCGCC
Downstream 100 bases:
>100_bases CGATGGAACGCGCCCTGCGCCACGTGGCCACACGGTTGGGTGAGCTGGACTGCCACGTCATCGACGCGCTCCCCGAGGGC GCGACGCCCGAACTGGTCGT
Product: cyclophilin-type peptidylprolyl cis-trans isomerase
Products: NA
Alternate protein names: PPIase B; Cyclophilin ScCypB; Rotamase B; S-cyclophilin [H]
Number of amino acids: Translated: 248; Mature: 248
Protein sequence:
>248_residues MRTQFLTTVLLCLTLTACKDSDKKESMGGGTPPSATTPAKPTAPSAAEVPAAAPPAEAASGEWTKKVQAGQDVYATLETN QGAIVVRLFSKDAPKTVANFVGLATGEKAWTDPKTGQRVEGKPLYDGVIFHRVIPGFMIQGGDPTGTGRGDPGYRFEDEF QSGRTFDKKGLLAMANAGPGTNGSQFFITTSTPDYLNNRHTIFGEVVSGYDVVEKISNVQRDPRDKPLEPVVIQKIAMSD QAPAGSGN
Sequences:
>Translated_248_residues MRTQFLTTVLLCLTLTACKDSDKKESMGGGTPPSATTPAKPTAPSAAEVPAAAPPAEAASGEWTKKVQAGQDVYATLETN QGAIVVRLFSKDAPKTVANFVGLATGEKAWTDPKTGQRVEGKPLYDGVIFHRVIPGFMIQGGDPTGTGRGDPGYRFEDEF QSGRTFDKKGLLAMANAGPGTNGSQFFITTSTPDYLNNRHTIFGEVVSGYDVVEKISNVQRDPRDKPLEPVVIQKIAMSD QAPAGSGN >Mature_248_residues MRTQFLTTVLLCLTLTACKDSDKKESMGGGTPPSATTPAKPTAPSAAEVPAAAPPAEAASGEWTKKVQAGQDVYATLETN QGAIVVRLFSKDAPKTVANFVGLATGEKAWTDPKTGQRVEGKPLYDGVIFHRVIPGFMIQGGDPTGTGRGDPGYRFEDEF QSGRTFDKKGLLAMANAGPGTNGSQFFITTSTPDYLNNRHTIFGEVVSGYDVVEKISNVQRDPRDKPLEPVVIQKIAMSD QAPAGSGN
Specific function: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides [H]
COG id: COG0652
COG function: function code O; Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family
Gene ontology:
Cell location: Cytoplasm [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 PPIase cyclophilin-type domain [H]
Homologues:
Organism=Homo sapiens, GI7706339, Length=167, Percent_Identity=45.5089820359281, Blast_Score=136, Evalue=1e-32, Organism=Homo sapiens, GI24308049, Length=210, Percent_Identity=40.9523809523809, Blast_Score=134, Evalue=6e-32, Organism=Homo sapiens, GI64276486, Length=163, Percent_Identity=44.1717791411043, Blast_Score=131, Evalue=4e-31, Organism=Homo sapiens, GI4758950, Length=198, Percent_Identity=41.4141414141414, Blast_Score=121, Evalue=5e-28, Organism=Homo sapiens, GI19557636, Length=169, Percent_Identity=37.2781065088757, Blast_Score=117, Evalue=8e-27, Organism=Homo sapiens, GI22547212, Length=193, Percent_Identity=40.4145077720207, Blast_Score=116, Evalue=2e-26, Organism=Homo sapiens, GI7657473, Length=193, Percent_Identity=40.4145077720207, Blast_Score=116, Evalue=2e-26, Organism=Homo sapiens, GI22547215, Length=193, Percent_Identity=40.4145077720207, Blast_Score=116, Evalue=2e-26, Organism=Homo sapiens, GI4505991, Length=155, Percent_Identity=45.8064516129032, Blast_Score=115, Evalue=3e-26, Organism=Homo sapiens, GI5454154, Length=159, Percent_Identity=45.2830188679245, Blast_Score=112, Evalue=4e-25, Organism=Homo sapiens, GI4826932, Length=157, Percent_Identity=45.2229299363057, Blast_Score=111, Evalue=6e-25, Organism=Homo sapiens, GI42560244, Length=175, Percent_Identity=44.5714285714286, Blast_Score=110, Evalue=8e-25, Organism=Homo sapiens, GI10863927, Length=143, Percent_Identity=44.0559440559441, Blast_Score=105, Evalue=3e-23, Organism=Homo sapiens, GI256017253, Length=137, Percent_Identity=43.7956204379562, Blast_Score=105, Evalue=3e-23, Organism=Homo sapiens, GI221139811, Length=137, Percent_Identity=43.7956204379562, Blast_Score=105, Evalue=3e-23, Organism=Homo sapiens, GI256017251, Length=137, Percent_Identity=43.7956204379562, Blast_Score=105, Evalue=3e-23, Organism=Homo sapiens, GI6631100, Length=159, Percent_Identity=42.7672955974843, Blast_Score=104, Evalue=6e-23, Organism=Homo sapiens, GI178057341, Length=141, Percent_Identity=42.5531914893617, Blast_Score=104, Evalue=6e-23, Organism=Homo sapiens, GI5031987, Length=155, Percent_Identity=44.5161290322581, Blast_Score=104, Evalue=7e-23, Organism=Homo sapiens, GI5174637, Length=189, Percent_Identity=38.6243386243386, Blast_Score=103, Evalue=1e-22, Organism=Homo sapiens, GI169163387, Length=140, Percent_Identity=42.8571428571429, Blast_Score=101, Evalue=5e-22, Organism=Homo sapiens, GI310129267, Length=146, Percent_Identity=39.7260273972603, Blast_Score=101, Evalue=6e-22, Organism=Homo sapiens, GI310120620, Length=146, Percent_Identity=39.7260273972603, Blast_Score=101, Evalue=6e-22, Organism=Homo sapiens, GI209417936, Length=141, Percent_Identity=41.8439716312057, Blast_Score=101, Evalue=7e-22, Organism=Homo sapiens, GI30102944, Length=141, Percent_Identity=41.8439716312057, Blast_Score=101, Evalue=7e-22, Organism=Homo sapiens, GI219842199, Length=141, Percent_Identity=41.8439716312057, Blast_Score=101, Evalue=7e-22, Organism=Homo sapiens, GI45439316, Length=172, Percent_Identity=39.5348837209302, Blast_Score=101, Evalue=7e-22, Organism=Homo sapiens, GI303305009, Length=175, Percent_Identity=38.8571428571429, Blast_Score=101, Evalue=8e-22, Organism=Homo sapiens, GI169164185, Length=140, Percent_Identity=42.8571428571429, Blast_Score=101, Evalue=8e-22, Organism=Homo sapiens, GI169163623, Length=140, Percent_Identity=42.8571428571429, Blast_Score=101, Evalue=8e-22, Organism=Homo sapiens, GI310110104, Length=141, Percent_Identity=38.2978723404255, Blast_Score=99, Evalue=3e-21, Organism=Homo sapiens, GI150418007, Length=143, Percent_Identity=43.3566433566434, Blast_Score=99, Evalue=4e-21, Organism=Homo sapiens, GI310127646, Length=141, Percent_Identity=41.8439716312057, Blast_Score=94, Evalue=1e-19, Organism=Homo sapiens, GI310114371, Length=141, Percent_Identity=41.8439716312057, Blast_Score=94, Evalue=1e-19, Organism=Homo sapiens, GI310119221, Length=141, Percent_Identity=41.8439716312057, Blast_Score=94, Evalue=1e-19, Organism=Homo sapiens, GI20911035, Length=173, Percent_Identity=33.5260115606936, Blast_Score=92, Evalue=5e-19, Organism=Homo sapiens, GI310132444, Length=143, Percent_Identity=39.1608391608392, Blast_Score=88, Evalue=8e-18, Organism=Homo sapiens, GI310113152, Length=143, Percent_Identity=39.1608391608392, Blast_Score=88, Evalue=8e-18, Organism=Homo sapiens, GI169214050, Length=141, Percent_Identity=41.1347517730496, Blast_Score=85, Evalue=6e-17, Organism=Homo sapiens, GI239751853, Length=141, Percent_Identity=41.1347517730496, Blast_Score=85, Evalue=6e-17, Organism=Homo sapiens, GI113428306, Length=141, Percent_Identity=41.1347517730496, Blast_Score=85, Evalue=6e-17, Organism=Homo sapiens, GI27735045, Length=143, Percent_Identity=35.6643356643357, Blast_Score=84, Evalue=1e-16, Organism=Homo sapiens, GI310127745, Length=134, Percent_Identity=41.7910447761194, Blast_Score=82, Evalue=6e-16, Organism=Homo sapiens, GI310119290, Length=134, Percent_Identity=41.7910447761194, Blast_Score=82, Evalue=6e-16, Organism=Homo sapiens, GI310114540, Length=137, Percent_Identity=40.8759124087591, Blast_Score=82, Evalue=6e-16, Organism=Homo sapiens, GI14277126, Length=97, Percent_Identity=36.0824742268041, Blast_Score=68, Evalue=7e-12, Organism=Escherichia coli, GI1786736, Length=186, Percent_Identity=33.8709677419355, Blast_Score=81, Evalue=6e-17, Organism=Escherichia coli, GI1789763, Length=196, Percent_Identity=32.1428571428571, Blast_Score=69, Evalue=4e-13, Organism=Caenorhabditis elegans, GI17539496, Length=165, Percent_Identity=42.4242424242424, Blast_Score=128, Evalue=2e-30, Organism=Caenorhabditis elegans, GI71980594, Length=167, Percent_Identity=38.3233532934132, Blast_Score=123, Evalue=8e-29, Organism=Caenorhabditis elegans, GI17552784, Length=159, Percent_Identity=45.9119496855346, Blast_Score=122, Evalue=1e-28, Organism=Caenorhabditis elegans, GI71980590, Length=157, Percent_Identity=39.4904458598726, Blast_Score=120, Evalue=5e-28, Organism=Caenorhabditis elegans, GI17506311, Length=169, Percent_Identity=42.603550295858, Blast_Score=118, Evalue=3e-27, Organism=Caenorhabditis elegans, GI17532641, Length=195, Percent_Identity=35.8974358974359, Blast_Score=118, Evalue=3e-27, Organism=Caenorhabditis elegans, GI17551282, Length=161, Percent_Identity=43.4782608695652, Blast_Score=117, Evalue=5e-27, Organism=Caenorhabditis elegans, GI17551284, Length=161, Percent_Identity=43.4782608695652, Blast_Score=117, Evalue=6e-27, Organism=Caenorhabditis elegans, GI17552780, Length=156, Percent_Identity=48.0769230769231, Blast_Score=116, Evalue=9e-27, Organism=Caenorhabditis elegans, GI17506307, Length=168, Percent_Identity=44.6428571428571, Blast_Score=112, Evalue=2e-25, Organism=Caenorhabditis elegans, GI17566266, Length=141, Percent_Identity=48.2269503546099, Blast_Score=108, Evalue=3e-24, Organism=Caenorhabditis elegans, GI17559074, Length=158, Percent_Identity=44.3037974683544, Blast_Score=107, Evalue=5e-24, Organism=Caenorhabditis elegans, GI17532643, Length=160, Percent_Identity=41.875, Blast_Score=106, Evalue=1e-23, Organism=Caenorhabditis elegans, GI17539498, Length=156, Percent_Identity=41.6666666666667, Blast_Score=103, Evalue=1e-22, Organism=Caenorhabditis elegans, GI17565860, Length=146, Percent_Identity=43.8356164383562, Blast_Score=100, Evalue=5e-22, Organism=Caenorhabditis elegans, GI71997782, Length=138, Percent_Identity=39.1304347826087, Blast_Score=98, Evalue=4e-21, Organism=Caenorhabditis elegans, GI17552782, Length=157, Percent_Identity=41.4012738853503, Blast_Score=94, Evalue=6e-20, Organism=Caenorhabditis elegans, GI32563659, Length=176, Percent_Identity=30.1136363636364, Blast_Score=87, Evalue=8e-18, Organism=Caenorhabditis elegans, GI115533296, Length=145, Percent_Identity=35.8620689655172, Blast_Score=76, Evalue=2e-14, Organism=Saccharomyces cerevisiae, GI6321848, Length=173, Percent_Identity=46.242774566474, Blast_Score=120, Evalue=3e-28, Organism=Saccharomyces cerevisiae, GI6323562, Length=161, Percent_Identity=44.0993788819876, Blast_Score=115, Evalue=6e-27, Organism=Saccharomyces cerevisiae, GI6320510, Length=156, Percent_Identity=45.5128205128205, Blast_Score=115, Evalue=6e-27, Organism=Saccharomyces cerevisiae, GI6320359, Length=154, Percent_Identity=45.4545454545455, Blast_Score=114, Evalue=1e-26, Organism=Saccharomyces cerevisiae, GI6323246, Length=162, Percent_Identity=46.2962962962963, Blast_Score=106, Evalue=4e-24, Organism=Saccharomyces cerevisiae, GI6322492, Length=178, Percent_Identity=36.5168539325843, Blast_Score=85, Evalue=8e-18, Organism=Drosophila melanogaster, GI19922376, Length=194, Percent_Identity=37.6288659793814, Blast_Score=140, Evalue=6e-34, Organism=Drosophila melanogaster, GI17986117, Length=171, Percent_Identity=43.859649122807, Blast_Score=139, Evalue=1e-33, Organism=Drosophila melanogaster, GI20130249, Length=156, Percent_Identity=47.4358974358974, Blast_Score=117, Evalue=5e-27, Organism=Drosophila melanogaster, GI24650807, Length=162, Percent_Identity=45.0617283950617, Blast_Score=116, Evalue=1e-26, Organism=Drosophila melanogaster, GI19922912, Length=176, Percent_Identity=44.3181818181818, Blast_Score=114, Evalue=6e-26, Organism=Drosophila melanogaster, GI45549139, Length=140, Percent_Identity=50, Blast_Score=114, Evalue=6e-26, Organism=Drosophila melanogaster, GI24664125, Length=140, Percent_Identity=47.8571428571429, Blast_Score=107, Evalue=9e-24, Organism=Drosophila melanogaster, GI21357783, Length=140, Percent_Identity=47.8571428571429, Blast_Score=107, Evalue=9e-24, Organism=Drosophila melanogaster, GI24586038, Length=162, Percent_Identity=41.358024691358, Blast_Score=105, Evalue=4e-23, Organism=Drosophila melanogaster, GI17647301, Length=139, Percent_Identity=42.4460431654676, Blast_Score=102, Evalue=2e-22, Organism=Drosophila melanogaster, GI24652460, Length=165, Percent_Identity=33.3333333333333, Blast_Score=101, Evalue=4e-22, Organism=Drosophila melanogaster, GI17136360, Length=171, Percent_Identity=38.5964912280702, Blast_Score=99, Evalue=2e-21, Organism=Drosophila melanogaster, GI21357249, Length=133, Percent_Identity=38.3458646616541, Blast_Score=94, Evalue=7e-20, Organism=Drosophila melanogaster, GI24661775, Length=160, Percent_Identity=33.75, Blast_Score=74, Evalue=1e-13, Organism=Drosophila melanogaster, GI21355237, Length=160, Percent_Identity=33.75, Blast_Score=74, Evalue=1e-13, Organism=Drosophila melanogaster, GI24661771, Length=160, Percent_Identity=33.75, Blast_Score=74, Evalue=1e-13, Organism=Drosophila melanogaster, GI21355677, Length=190, Percent_Identity=29.4736842105263, Blast_Score=70, Evalue=2e-12,
Paralogues:
None
Copy number: 780 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR015891 - InterPro: IPR020892 - InterPro: IPR002130 [H]
Pfam domain/function: PF00160 Pro_isomerase [H]
EC number: =5.2.1.8 [H]
Molecular weight: Translated: 26265; Mature: 26265
Theoretical pI: Translated: 6.54; Mature: 6.54
Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS00170 CSA_PPIASE_1 ; PS50072 CSA_PPIASE_2
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.8 %Cys (Translated Protein) 2.0 %Met (Translated Protein) 2.8 %Cys+Met (Translated Protein) 0.8 %Cys (Mature Protein) 2.0 %Met (Mature Protein) 2.8 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MRTQFLTTVLLCLTLTACKDSDKKESMGGGTPPSATTPAKPTAPSAAEVPAAAPPAEAAS CCHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC GEWTKKVQAGQDVYATLETNQGAIVVRLFSKDAPKTVANFVGLATGEKAWTDPKTGQRVE CCHHHHHHCCCCEEEEEECCCCEEEEEEECCCCHHHHHHHHHCCCCCCCCCCCCCCCCCC GKPLYDGVIFHRVIPGFMIQGGDPTGTGRGDPGYRFEDEFQSGRTFDKKGLLAMANAGPG CCCCHHHHHHHHHCCCEEEECCCCCCCCCCCCCCCCCHHHHCCCCCCCCCCEEEECCCCC TNGSQFFITTSTPDYLNNRHTIFGEVVSGYDVVEKISNVQRDPRDKPLEPVVIQKIAMSD CCCCEEEEECCCHHHHCCCCEEHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCC QAPAGSGN CCCCCCCC >Mature Secondary Structure MRTQFLTTVLLCLTLTACKDSDKKESMGGGTPPSATTPAKPTAPSAAEVPAAAPPAEAAS CCHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC GEWTKKVQAGQDVYATLETNQGAIVVRLFSKDAPKTVANFVGLATGEKAWTDPKTGQRVE CCHHHHHHCCCCEEEEEECCCCEEEEEEECCCCHHHHHHHHHCCCCCCCCCCCCCCCCCC GKPLYDGVIFHRVIPGFMIQGGDPTGTGRGDPGYRFEDEFQSGRTFDKKGLLAMANAGPG CCCCHHHHHHHHHCCCEEEECCCCCCCCCCCCCCCCCHHHHCCCCCCCCCCEEEECCCCC TNGSQFFITTSTPDYLNNRHTIFGEVVSGYDVVEKISNVQRDPRDKPLEPVVIQKIAMSD CCCCEEEEECCCHHHHCCCCEEHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCC QAPAGSGN CCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 9025285 [H]