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The map label for this gene is ppiD [H]

Identifier: 108758423

GI number: 108758423

Start: 3086791

End: 3088365

Strand: Reverse

Name: ppiD [H]

Synonym: MXAN_2644

Alternate gene names: 108758423

Gene position: 3088365-3086791 (Counterclockwise)

Preceding gene: 108757073

Following gene: 108762487

Centisome position: 33.79

GC content: 68.7

Gene sequence:

>1575_bases
GTGACGACAATGGACGGTCTGAATCCCCGGAAGGTTGCCTCGCTCCTGTTCATCATCGGCATCGCGGTGGTGTTCACGCT
CCAGTTCGGCCCGGGCAGTTCTGGCTTCGGCGCCACGGGTGGGGCGACGGCGCCCGGTTCGGTGGCCTCGGTGAACGGCA
AGGAAATCCCGCTGCGTGACTTCGCCGCGGCCTGGGCCCAGCAGATGAGCTTCCTGCGCTCGCAGGGCAGCCCGGTGCCC
GAGTCGCTCGCCCGCCAGTTCGGCATGCATAACCAGGTGCTCGACCGGTTGGTGAACACGGAGCTGCTGGCCCAGGCGGC
CGAGCGCCACGGCATCGCCGCGTCCGACGATGAGCTGCGCAAGCTCATCCACCAGAACACGGACTTCCAGAAGGATGGCC
AGTTCGACTTCGAGCGCTACCAGCAGGTGCTGCGCGACTTCTACCGGAAGTCCCCGCAGGACTTCGAGGCGGAGCTGCGC
CGGCAATTGGCGGCCCAGAAGATGATGGACGTGGTGCGCGGCAACGCGGTGGTGTCGGACGACGAGGTCCGCGCCCGCTT
CGAGAAGGAAGGCAACCAGGCGAAGGTCGTCTTCGCGCGCTTCCTGCCGGCCATGTACGCCGACAAGGTCCCCAGCCCCA
CCGCGGCGCAGCTGGCCGAGTGGAAGAAGGCGCACGAGAAGGACATCAAGGAGTACTTCGAGGCCAACCGCTTCGTGTAC
CAGCAGCCGGAGCGCATCCGTGCGCGGCAGGTGCTGGTGAAGCTGCCCCCGGAGGCCACCGCCGACCAGAAGAAGGCGGC
CCTGGAGAAGGCGCAGGCGCTGCGCAAGGAAATCGAGGGCGGCAAGGACTTCGCCCAGGTGGCGCGTGACAGCAGCGAGG
ACCCGGGCAGCAAGGCGCGCGGTGGCGACCTGGGCTGGGTGGAGCGCGGCAGCTGGGAACCGGCGCTGGCGGACGCGGCC
TTCGCGCTGAAGCAGGGCGAGGTGACGCAGCCGGTGGAGACGAAGTTCGGCGTGCACCTGGTGAAGGTGGATGAGAAGCA
GGCCGCCCAGGACAAGAAGCTCGAGGACGTCCAGGACGAGATTGCCACCACGCTCTACAAGCAGGACCGCGCCAAGCAGC
AGGCCCGCGCCGAGGCGGAGAAGGCGTTGGCCTCCGCCAAGGCGGGCCAGGACCTGAAGACGCTCTTCCCGCCGGAGAAG
GAGCAGCCCGCGCTGCTGCGCTTCGAGACGGAGACGCGCCCGGAGGCCGTGGAGACGGACAGCTTCACCGCCGAGGGTGA
GGCGGTGCCTCACCTGGGCCCCGCGCCCGAACTGGTGAAGGCGGCCTTCGCCGTCAGCGCCCCGCAGCCGCTCGACAGCG
TGTTCCCCCTGGGTGAGGGCTTCGTGGTGGCGCAGGTGGTGGAGCGCCAGAAGCCGGACGCCGAGGGCTTTGACAAGCGC
AAGGAGGAACTGCGCGCCCAGGCCCGTCAGGCCAAGCAGATTGAGCTGACGGAGTCCTTCCTCAAGGCGCTGCGTGAGCA
GGGCTCGGTGGTAACGAACACCGCCGCCATCGACTCCGTGGTGGGCACCGGGTGA

Upstream 100 bases:

>100_bases
TGGGGGGCGGTTCCTGGTCCACCACCCACCGGCCGGGCTACCAACAACACCGCGTCGCGAGTCCTTCCGCACGGCTTTTC
TCGGCGCGTTTGCCCCAGAA

Downstream 100 bases:

>100_bases
GTCCCGGCGTCCAACCGTGACGCCCCCGAGGGCCGGGCCGAGGGTACTCCCCTCCCCGGCCCTCTCTCATTGCGGGCTTC
GCGGCCAACAGCGCCGAAGC

Product: peptidylprolyl cis-trans isomerase

Products: NA

Alternate protein names: PPIase D; Rotamase D [H]

Number of amino acids: Translated: 524; Mature: 523

Protein sequence:

>524_residues
MTTMDGLNPRKVASLLFIIGIAVVFTLQFGPGSSGFGATGGATAPGSVASVNGKEIPLRDFAAAWAQQMSFLRSQGSPVP
ESLARQFGMHNQVLDRLVNTELLAQAAERHGIAASDDELRKLIHQNTDFQKDGQFDFERYQQVLRDFYRKSPQDFEAELR
RQLAAQKMMDVVRGNAVVSDDEVRARFEKEGNQAKVVFARFLPAMYADKVPSPTAAQLAEWKKAHEKDIKEYFEANRFVY
QQPERIRARQVLVKLPPEATADQKKAALEKAQALRKEIEGGKDFAQVARDSSEDPGSKARGGDLGWVERGSWEPALADAA
FALKQGEVTQPVETKFGVHLVKVDEKQAAQDKKLEDVQDEIATTLYKQDRAKQQARAEAEKALASAKAGQDLKTLFPPEK
EQPALLRFETETRPEAVETDSFTAEGEAVPHLGPAPELVKAAFAVSAPQPLDSVFPLGEGFVVAQVVERQKPDAEGFDKR
KEELRAQARQAKQIELTESFLKALREQGSVVTNTAAIDSVVGTG

Sequences:

>Translated_524_residues
MTTMDGLNPRKVASLLFIIGIAVVFTLQFGPGSSGFGATGGATAPGSVASVNGKEIPLRDFAAAWAQQMSFLRSQGSPVP
ESLARQFGMHNQVLDRLVNTELLAQAAERHGIAASDDELRKLIHQNTDFQKDGQFDFERYQQVLRDFYRKSPQDFEAELR
RQLAAQKMMDVVRGNAVVSDDEVRARFEKEGNQAKVVFARFLPAMYADKVPSPTAAQLAEWKKAHEKDIKEYFEANRFVY
QQPERIRARQVLVKLPPEATADQKKAALEKAQALRKEIEGGKDFAQVARDSSEDPGSKARGGDLGWVERGSWEPALADAA
FALKQGEVTQPVETKFGVHLVKVDEKQAAQDKKLEDVQDEIATTLYKQDRAKQQARAEAEKALASAKAGQDLKTLFPPEK
EQPALLRFETETRPEAVETDSFTAEGEAVPHLGPAPELVKAAFAVSAPQPLDSVFPLGEGFVVAQVVERQKPDAEGFDKR
KEELRAQARQAKQIELTESFLKALREQGSVVTNTAAIDSVVGTG
>Mature_523_residues
TTMDGLNPRKVASLLFIIGIAVVFTLQFGPGSSGFGATGGATAPGSVASVNGKEIPLRDFAAAWAQQMSFLRSQGSPVPE
SLARQFGMHNQVLDRLVNTELLAQAAERHGIAASDDELRKLIHQNTDFQKDGQFDFERYQQVLRDFYRKSPQDFEAELRR
QLAAQKMMDVVRGNAVVSDDEVRARFEKEGNQAKVVFARFLPAMYADKVPSPTAAQLAEWKKAHEKDIKEYFEANRFVYQ
QPERIRARQVLVKLPPEATADQKKAALEKAQALRKEIEGGKDFAQVARDSSEDPGSKARGGDLGWVERGSWEPALADAAF
ALKQGEVTQPVETKFGVHLVKVDEKQAAQDKKLEDVQDEIATTLYKQDRAKQQARAEAEKALASAKAGQDLKTLFPPEKE
QPALLRFETETRPEAVETDSFTAEGEAVPHLGPAPELVKAAFAVSAPQPLDSVFPLGEGFVVAQVVERQKPDAEGFDKRK
EELRAQARQAKQIELTESFLKALREQGSVVTNTAAIDSVVGTG

Specific function: PPIases accelerate the folding of proteins. Seems to be involved in the folding of outer membrane proteins [H]

COG id: COG0760

COG function: function code O; Parvulin-like peptidyl-prolyl isomerase

Gene ontology:

Cell location: Cell membrane; Single-pass type II membrane protein; Periplasmic side (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PpiC domain [H]

Homologues:

Organism=Escherichia coli, GI1786645, Length=400, Percent_Identity=27.25, Blast_Score=108, Evalue=8e-25,
Organism=Escherichia coli, GI1786238, Length=112, Percent_Identity=39.2857142857143, Blast_Score=76, Evalue=6e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000297
- InterPro:   IPR023058
- InterPro:   IPR008880 [H]

Pfam domain/function: PF00639 Rotamase [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 57659; Mature: 57528

Theoretical pI: Translated: 5.51; Mature: 5.51

Prosite motif: PS01096 PPIC_PPIASE_1 ; PS50198 PPIC_PPIASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHCCC
>Mature Secondary Structure 
TTMDGLNPRKVASLLFIIGIAVVFTLQFGPGSSGFGATGGATAPGSVASVNGKEIPLRD
CCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEECCCCCCCHHH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HHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]