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The map label for this gene is resA [H]

Identifier: 108758314

GI number: 108758314

Start: 2244015

End: 2244425

Strand: Direct

Name: resA [H]

Synonym: MXAN_1913

Alternate gene names: 108758314

Gene position: 2244015-2244425 (Clockwise)

Preceding gene: 108758004

Following gene: 108762085

Centisome position: 24.55

GC content: 67.64

Gene sequence:

>411_bases
GTGAAGCGCTATCCCGGCGGCGAGCCGTATGACCTCGCCTCGGACCGGGGCAGCGTGGTGGTGCTCGACGTGTGGGCCAC
CTGGTGCGAGCCCTGCAAGGACGCGCTTCCCTACTACCAGGACCTCGCGAACGAGTACGCAGCCCAGGGCCTGAAGGTGT
ACGCGCTCAACATCGACGAGGACCCGCGCGCCATCCCCGCCTTCCTGGCGGAGACGAAGGTGACGCTGCCCATCCTCCTG
GACCAGAACGCCCAGGTGGCCGAGCGCACCCTCAAGGTGCGGGGCATGCCCACCACGTATTTCATCGACCGCAAGGGCAT
GGTGCGCCACGTCCATGAAGGCTTCGCCGAGGAGTTCCTCGCGAAGTACCAGACGGAGCTCGAGGCGCTGCTCGCCGAGC
CCACCCCGTAG

Upstream 100 bases:

>100_bases
CGGCTGTGCGAGCGCTCCCGCCATTCCGCCTCTGGGGCCAGAGGGGCAGGGGACTTCGCAGCGCAGCGGGCTCAAGGGCT
CGCAGCCGCTGGACTTCCAG

Downstream 100 bases:

>100_bases
AGGAGAGCGTCATGTCCCAGGATTCGCCCGACAGCCTGCGCCGCACCGCCGAGGAGGGGGCTCGGCTCGCTGGCCGCATC
CTCGCGGACCGGTTCCTGGG

Product: thioredoxin family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 136; Mature: 136

Protein sequence:

>136_residues
MKRYPGGEPYDLASDRGSVVVLDVWATWCEPCKDALPYYQDLANEYAAQGLKVYALNIDEDPRAIPAFLAETKVTLPILL
DQNAQVAERTLKVRGMPTTYFIDRKGMVRHVHEGFAEEFLAKYQTELEALLAEPTP

Sequences:

>Translated_136_residues
MKRYPGGEPYDLASDRGSVVVLDVWATWCEPCKDALPYYQDLANEYAAQGLKVYALNIDEDPRAIPAFLAETKVTLPILL
DQNAQVAERTLKVRGMPTTYFIDRKGMVRHVHEGFAEEFLAKYQTELEALLAEPTP
>Mature_136_residues
MKRYPGGEPYDLASDRGSVVVLDVWATWCEPCKDALPYYQDLANEYAAQGLKVYALNIDEDPRAIPAFLAETKVTLPILL
DQNAQVAERTLKVRGMPTTYFIDRKGMVRHVHEGFAEEFLAKYQTELEALLAEPTP

Specific function: Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c; following this reduction heme can be covalent

COG id: COG0526

COG function: function code OC; Thiol-disulfide isomerase and thioredoxins

Gene ontology:

Cell location: Cell membrane; Single-pass type II membrane protein. Note=The thioredoxin-like motif is exposed on the outside of the membrane (By similarity) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000866
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00578 AhpC-TSA [H]

EC number: NA

Molecular weight: Translated: 15350; Mature: 15350

Theoretical pI: Translated: 4.54; Mature: 4.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRYPGGEPYDLASDRGSVVVLDVWATWCEPCKDALPYYQDLANEYAAQGLKVYALNIDE
CCCCCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCC
DPRAIPAFLAETKVTLPILLDQNAQVAERTLKVRGMPTTYFIDRKGMVRHVHEGFAEEFL
CCCHHHHHHHHCCCEEEEEECCCCHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHHHH
AKYQTELEALLAEPTP
HHHHHHHHHHHCCCCC
>Mature Secondary Structure
MKRYPGGEPYDLASDRGSVVVLDVWATWCEPCKDALPYYQDLANEYAAQGLKVYALNIDE
CCCCCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCC
DPRAIPAFLAETKVTLPILLDQNAQVAERTLKVRGMPTTYFIDRKGMVRHVHEGFAEEFL
CCCHHHHHHHHCCCEEEEEECCCCHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHHHH
AKYQTELEALLAEPTP
HHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12235376 [H]